Bengt Sennblad

Bengt Sennblad

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Bengt Sennblad

Bengt Sennblad

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GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

Authors:
Nora Franceschini Claudia Giambartolomei Paul S de Vries Chris Finan Joshua C Bis Rachael P Huntley Ruth C Lovering Salman M Tajuddin Thomas W Winkler Misa Graff Maryam Kavousi Caroline Dale Albert V Smith Edith Hofer Elisabeth M van Leeuwen Ilja M Nolte Lingyi Lu Markus Scholz Muralidharan Sargurupremraj Niina Pitkänen Oscar Franzén Peter K Joshi Raymond Noordam Riccardo E Marioni Shih-Jen Hwang Solomon K Musani Ulf Schminke Walter Palmas Aaron Isaacs Adolfo Correa Alan B Zonderman Albert Hofman Alexander Teumer Amanda J Cox André G Uitterlinden Andrew Wong Andries J Smit Anne B Newman Annie Britton Arno Ruusalepp Bengt Sennblad Bo Hedblad Bogdan Pasaniuc Brenda W Penninx Carl D Langefeld Christina L Wassel Christophe Tzourio Cristiano Fava Damiano Baldassarre Daniel H O'Leary Daniel Teupser Diana Kuh Elena Tremoli Elmo Mannarino Enzo Grossi Eric Boerwinkle Eric E Schadt Erik Ingelsson Fabrizio Veglia Fernando Rivadeneira Frank Beutner Ganesh Chauhan Gerardo Heiss Harold Snieder Harry Campbell Henry Völzke Hugh S Markus Ian J Deary J Wouter Jukema Jacqueline de Graaf Jacqueline Price Janne Pott Jemma C Hopewell Jingjing Liang Joachim Thiery Jorgen Engmann Karl Gertow Kenneth Rice Kent D Taylor Klodian Dhana Lambertus A L M Kiemeney Lars Lind Laura M Raffield Lenore J Launer Lesca M Holdt Marcus Dörr Martin Dichgans Matthew Traylor Matthias Sitzer Meena Kumari Mika Kivimaki Mike A Nalls Olle Melander Olli Raitakari Oscar H Franco Oscar L Rueda-Ochoa Panos Roussos Peter H Whincup Philippe Amouyel Philippe Giral Pramod Anugu Quenna Wong Rainer Malik Rainer Rauramaa Ralph Burkhardt Rebecca Hardy Reinhold Schmidt Renée de Mutsert Richard W Morris Rona J Strawbridge S Goya Wannamethee Sara Hägg Sonia Shah Stela McLachlan Stella Trompet Sudha Seshadri Sudhir Kurl Susan R Heckbert Susan Ring Tamara B Harris Terho Lehtimäki Tessel E Galesloot Tina Shah Ulf de Faire Vincent Plagnol Wayne D Rosamond Wendy Post Xiaofeng Zhu Xiaoling Zhang Xiuqing Guo Yasaman Saba Abbas Dehghan Adrie Seldenrijk Alanna C Morrison Anders Hamsten Bruce M Psaty Cornelia M van Duijn Deborah A Lawlor Dennis O Mook-Kanamori Donald W Bowden Helena Schmidt James F Wilson James G Wilson Jerome I Rotter Joanna M Wardlaw John Deanfield Julian Halcox Leo-Pekka Lyytikäinen Markus Loeffler Michele K Evans Stéphanie Debette Steve E Humphries Uwe Völker Vilmundur Gudnason Aroon D Hingorani Johan L M Björkegren Juan P Casas Christopher J O'Donnell

Nat Commun 2018 12 3;9(1):5141. Epub 2018 Dec 3.

Intramural Administration Management Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-07340-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277418PMC
December 2018

H19 Induces Abdominal Aortic Aneurysm Development and Progression.

Circulation 2018 Oct;138(15):1551-1568

Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar (D.Y.L., A. Busch, J.P., S.L., H.-H.E., L.M.), Technical University Munich, and German Center for Cardiovascular Research (DZHK), partner site Munich, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.032184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193867PMC
October 2018

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.

Authors:
Robert A Scott Laura J Scott Reedik Mägi Letizia Marullo Kyle J Gaulton Marika Kaakinen Natalia Pervjakova Tune H Pers Andrew D Johnson John D Eicher Anne U Jackson Teresa Ferreira Yeji Lee Clement Ma Valgerdur Steinthorsdottir Gudmar Thorleifsson Lu Qi Natalie R Van Zuydam Anubha Mahajan Han Chen Peter Almgren Ben F Voight Harald Grallert Martina Müller-Nurasyid Janina S Ried Nigel W Rayner Neil Robertson Lennart C Karssen Elisabeth M van Leeuwen Sara M Willems Christian Fuchsberger Phoenix Kwan Tanya M Teslovich Pritam Chanda Man Li Yingchang Lu Christian Dina Dorothee Thuillier Loic Yengo Longda Jiang Thomas Sparso Hans A Kestler Himanshu Chheda Lewin Eisele Stefan Gustafsson Mattias Frånberg Rona J Strawbridge Rafn Benediktsson Astradur B Hreidarsson Augustine Kong Gunnar Sigurðsson Nicola D Kerrison Jian'an Luan Liming Liang Thomas Meitinger Michael Roden Barbara Thorand Tõnu Esko Evelin Mihailov Caroline Fox Ching-Ti Liu Denis Rybin Bo Isomaa Valeriya Lyssenko Tiinamaija Tuomi David J Couper James S Pankow Niels Grarup Christian T Have Marit E Jørgensen Torben Jørgensen Allan Linneberg Marilyn C Cornelis Rob M van Dam David J Hunter Peter Kraft Qi Sun Sarah Edkins Katharine R Owen John R B Perry Andrew R Wood Eleftheria Zeggini Juan Tajes-Fernandes Goncalo R Abecasis Lori L Bonnycastle Peter S Chines Heather M Stringham Heikki A Koistinen Leena Kinnunen Bengt Sennblad Thomas W Mühleisen Markus M Nöthen Sonali Pechlivanis Damiano Baldassarre Karl Gertow Steve E Humphries Elena Tremoli Norman Klopp Julia Meyer Gerald Steinbach Roman Wennauer Johan G Eriksson Satu Mӓnnistö Leena Peltonen Emmi Tikkanen Guillaume Charpentier Elodie Eury Stéphane Lobbens Bruna Gigante Karin Leander Olga McLeod Erwin P Bottinger Omri Gottesman Douglas Ruderfer Matthias Blüher Peter Kovacs Anke Tonjes Nisa M Maruthur Chiara Scapoli Raimund Erbel Karl-Heinz Jöckel Susanne Moebus Ulf de Faire Anders Hamsten Michael Stumvoll Panagiotis Deloukas Peter J Donnelly Timothy M Frayling Andrew T Hattersley Samuli Ripatti Veikko Salomaa Nancy L Pedersen Bernhard O Boehm Richard N Bergman Francis S Collins Karen L Mohlke Jaakko Tuomilehto Torben Hansen Oluf Pedersen Inês Barroso Lars Lannfelt Erik Ingelsson Lars Lind Cecilia M Lindgren Stephane Cauchi Philippe Froguel Ruth J F Loos Beverley Balkau Heiner Boeing Paul W Franks Aurelio Barricarte Gurrea Domenico Palli Yvonne T van der Schouw David Altshuler Leif C Groop Claudia Langenberg Nicholas J Wareham Eric Sijbrands Cornelia M van Duijn Jose C Florez James B Meigs Eric Boerwinkle Christian Gieger Konstantin Strauch Andres Metspalu Andrew D Morris Colin N A Palmer Frank B Hu Unnur Thorsteinsdottir Kari Stefansson Josée Dupuis Andrew P Morris Michael Boehnke Mark I McCarthy Inga Prokopenko

Diabetes 2017 11 31;66(11):2888-2902. Epub 2017 May 31.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db16-1253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652602PMC
November 2017

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

Authors:
Eleanor Wheeler Aaron Leong Ching-Ti Liu Marie-France Hivert Rona J Strawbridge Clara Podmore Man Li Jie Yao Xueling Sim Jaeyoung Hong Audrey Y Chu Weihua Zhang Xu Wang Peng Chen Nisa M Maruthur Bianca C Porneala Stephen J Sharp Yucheng Jia Edmond K Kabagambe Li-Ching Chang Wei-Min Chen Cathy E Elks Daniel S Evans Qiao Fan Franco Giulianini Min Jin Go Jouke-Jan Hottenga Yao Hu Anne U Jackson Stavroula Kanoni Young Jin Kim Marcus E Kleber Claes Ladenvall Cecile Lecoeur Sing-Hui Lim Yingchang Lu Anubha Mahajan Carola Marzi Mike A Nalls Pau Navarro Ilja M Nolte Lynda M Rose Denis V Rybin Serena Sanna Yuan Shi Daniel O Stram Fumihiko Takeuchi Shu Pei Tan Peter J van der Most Jana V Van Vliet-Ostaptchouk Andrew Wong Loic Yengo Wanting Zhao Anuj Goel Maria Teresa Martinez Larrad Dörte Radke Perttu Salo Toshiko Tanaka Erik P A van Iperen Goncalo Abecasis Saima Afaq Behrooz Z Alizadeh Alain G Bertoni Amelie Bonnefond Yvonne Böttcher Erwin P Bottinger Harry Campbell Olga D Carlson Chien-Hsiun Chen Yoon Shin Cho W Timothy Garvey Christian Gieger Mark O Goodarzi Harald Grallert Anders Hamsten Catharina A Hartman Christian Herder Chao Agnes Hsiung Jie Huang Michiya Igase Masato Isono Tomohiro Katsuya Chiea-Chuen Khor Wieland Kiess Katsuhiko Kohara Peter Kovacs Juyoung Lee Wen-Jane Lee Benjamin Lehne Huaixing Li Jianjun Liu Stephane Lobbens Jian'an Luan Valeriya Lyssenko Thomas Meitinger Tetsuro Miki Iva Miljkovic Sanghoon Moon Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Ramaiah Nagaraja Matthias Nauck James S Pankow Ozren Polasek Inga Prokopenko Paula S Ramos Laura Rasmussen-Torvik Wolfgang Rathmann Stephen S Rich Neil R Robertson Michael Roden Ronan Roussel Igor Rudan Robert A Scott William R Scott Bengt Sennblad David S Siscovick Konstantin Strauch Liang Sun Morris Swertz Salman M Tajuddin Kent D Taylor Yik-Ying Teo Yih Chung Tham Anke Tönjes Nicholas J Wareham Gonneke Willemsen Tom Wilsgaard Aroon D Hingorani Josephine Egan Luigi Ferrucci G Kees Hovingh Antti Jula Mika Kivimaki Meena Kumari Inger Njølstad Colin N A Palmer Manuel Serrano Ríos Michael Stumvoll Hugh Watkins Tin Aung Matthias Blüher Michael Boehnke Dorret I Boomsma Stefan R Bornstein John C Chambers Daniel I Chasman Yii-Der Ida Chen Yduan-Tsong Chen Ching-Yu Cheng Francesco Cucca Eco J C de Geus Panos Deloukas Michele K Evans Myriam Fornage Yechiel Friedlander Philippe Froguel Leif Groop Myron D Gross Tamara B Harris Caroline Hayward Chew-Kiat Heng Erik Ingelsson Norihiro Kato Bong-Jo Kim Woon-Puay Koh Jaspal S Kooner Antje Körner Diana Kuh Johanna Kuusisto Markku Laakso Xu Lin Yongmei Liu Ruth J F Loos Patrik K E Magnusson Winfried März Mark I McCarthy Albertine J Oldehinkel Ken K Ong Nancy L Pedersen Mark A Pereira Annette Peters Paul M Ridker Charumathi Sabanayagam Michele Sale Danish Saleheen Juha Saltevo Peter Eh Schwarz Wayne H H Sheu Harold Snieder Timothy D Spector Yasuharu Tabara Jaakko Tuomilehto Rob M van Dam James G Wilson James F Wilson Bruce H R Wolffenbuttel Tien Yin Wong Jer-Yuarn Wu Jian-Min Yuan Alan B Zonderman Nicole Soranzo Xiuqing Guo David J Roberts Jose C Florez Robert Sladek Josée Dupuis Andrew P Morris E-Shyong Tai Elizabeth Selvin Jerome I Rotter Claudia Langenberg Inês Barroso James B Meigs

PLoS Med 2017 Sep 12;14(9):e1002383. Epub 2017 Sep 12.

Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595282PMC
September 2017

Fast and general tests of genetic interaction for genome-wide association studies.

PLoS Comput Biol 2017 Jun 6;13(6):e1005556. Epub 2017 Jun 6.

Cardiovascular Medicine Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1371/journal.pcbi.1005556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478145PMC
June 2017

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

Authors:
Anne E Justice Thomas W Winkler Mary F Feitosa Misa Graff Virginia A Fisher Kristin Young Llilda Barata Xuan Deng Jacek Czajkowski David Hadley Julius S Ngwa Tarunveer S Ahluwalia Audrey Y Chu Nancy L Heard-Costa Elise Lim Jeremiah Perez John D Eicher Zoltán Kutalik Luting Xue Anubha Mahajan Frida Renström Joseph Wu Qibin Qi Shafqat Ahmad Tamuno Alfred Najaf Amin Lawrence F Bielak Amelie Bonnefond Jennifer Bragg Gemma Cadby Martina Chittani Scott Coggeshall Tanguy Corre Nese Direk Joel Eriksson Krista Fischer Mathias Gorski Marie Neergaard Harder Momoko Horikoshi Tao Huang Jennifer E Huffman Anne U Jackson Johanne Marie Justesen Stavroula Kanoni Leena Kinnunen Marcus E Kleber Pirjo Komulainen Meena Kumari Unhee Lim Jian'an Luan Leo-Pekka Lyytikäinen Massimo Mangino Ani Manichaikul Jonathan Marten Rita P S Middelberg Martina Müller-Nurasyid Pau Navarro Louis Pérusse Natalia Pervjakova Cinzia Sarti Albert Vernon Smith Jennifer A Smith Alena Stančáková Rona J Strawbridge Heather M Stringham Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Peter J van der Most Jana V Van Vliet-Ostaptchouk Sailaja L Vedantam Niek Verweij Jacqueline M Vink Veronique Vitart Ying Wu Loic Yengo Weihua Zhang Jing Hua Zhao Martina E Zimmermann Niha Zubair Gonçalo R Abecasis Linda S Adair Saima Afaq Uzma Afzal Stephan J L Bakker Traci M Bartz John Beilby Richard N Bergman Sven Bergmann Reiner Biffar John Blangero Eric Boerwinkle Lori L Bonnycastle Erwin Bottinger Daniele Braga Brendan M Buckley Steve Buyske Harry Campbell John C Chambers Francis S Collins Joanne E Curran Gert J de Borst Anton J M de Craen Eco J C de Geus George Dedoussis Graciela E Delgado Hester M den Ruijter Gudny Eiriksdottir Anna L Eriksson Tõnu Esko Jessica D Faul Ian Ford Terrence Forrester Karl Gertow Bruna Gigante Nicola Glorioso Jian Gong Harald Grallert Tanja B Grammer Niels Grarup Saskia Haitjema Göran Hallmans Anders Hamsten Torben Hansen Tamara B Harris Catharina A Hartman Maija Hassinen Nicholas D Hastie Andrew C Heath Dena Hernandez Lucia Hindorff Lynne J Hocking Mette Hollensted Oddgeir L Holmen Georg Homuth Jouke Jan Hottenga Jie Huang Joseph Hung Nina Hutri-Kähönen Erik Ingelsson Alan L James John-Olov Jansson Marjo-Riitta Jarvelin Min A Jhun Marit E Jørgensen Markus Juonala Mika Kähönen Magnus Karlsson Heikki A Koistinen Ivana Kolcic Genovefa Kolovou Charles Kooperberg Bernhard K Krämer Johanna Kuusisto Kirsti Kvaløy Timo A Lakka Claudia Langenberg Lenore J Launer Karin Leander Nanette R Lee Lars Lind Cecilia M Lindgren Allan Linneberg Stephane Lobbens Marie Loh Mattias Lorentzon Robert Luben Gitta Lubke Anja Ludolph-Donislawski Sara Lupoli Pamela A F Madden Reija Männikkö Pedro Marques-Vidal Nicholas G Martin Colin A McKenzie Barbara McKnight Dan Mellström Cristina Menni Grant W Montgomery Aw Bill Musk Narisu Narisu Matthias Nauck Ilja M Nolte Albertine J Oldehinkel Matthias Olden Ken K Ong Sandosh Padmanabhan Patricia A Peyser Charlotta Pisinger David J Porteous Olli T Raitakari Tuomo Rankinen D C Rao Laura J Rasmussen-Torvik Rajesh Rawal Treva Rice Paul M Ridker Lynda M Rose Stephanie A Bien Igor Rudan Serena Sanna Mark A Sarzynski Naveed Sattar Kai Savonen David Schlessinger Salome Scholtens Claudia Schurmann Robert A Scott Bengt Sennblad Marten A Siemelink Günther Silbernagel P Eline Slagboom Harold Snieder Jan A Staessen David J Stott Morris A Swertz Amy J Swift Kent D Taylor Bamidele O Tayo Barbara Thorand Dorothee Thuillier Jaakko Tuomilehto Andre G Uitterlinden Liesbeth Vandenput Marie-Claude Vohl Henry Völzke Judith M Vonk Gérard Waeber Melanie Waldenberger R G J Westendorp Sarah Wild Gonneke Willemsen Bruce H R Wolffenbuttel Andrew Wong Alan F Wright Wei Zhao M Carola Zillikens Damiano Baldassarre Beverley Balkau Stefania Bandinelli Carsten A Böger Dorret I Boomsma Claude Bouchard Marcel Bruinenberg Daniel I Chasman Yii-DerIda Chen Peter S Chines Richard S Cooper Francesco Cucca Daniele Cusi Ulf de Faire Luigi Ferrucci Paul W Franks Philippe Froguel Penny Gordon-Larsen Hans-Jörgen Grabe Vilmundur Gudnason Christopher A Haiman Caroline Hayward Kristian Hveem Andrew D Johnson J Wouter Jukema Sharon L R Kardia Mika Kivimaki Jaspal S Kooner Diana Kuh Markku Laakso Terho Lehtimäki Loic Le Marchand Winfried März Mark I McCarthy Andres Metspalu Andrew P Morris Claes Ohlsson Lyle J Palmer Gerard Pasterkamp Oluf Pedersen Annette Peters Ulrike Peters Ozren Polasek Bruce M Psaty Lu Qi Rainer Rauramaa Blair H Smith Thorkild I A Sørensen Konstantin Strauch Henning Tiemeier Elena Tremoli Pim van der Harst Henrik Vestergaard Peter Vollenweider Nicholas J Wareham David R Weir John B Whitfield James F Wilson Jessica Tyrrell Timothy M Frayling Inês Barroso Michael Boehnke Panagiotis Deloukas Caroline S Fox Joel N Hirschhorn David J Hunter Tim D Spector David P Strachan Cornelia M van Duijn Iris M Heid Karen L Mohlke Jonathan Marchini Ruth J F Loos Tuomas O Kilpeläinen Ching-Ti Liu Ingrid B Borecki Kari E North L Adrienne Cupples

Nat Commun 2017 04 26;8:14977. Epub 2017 Apr 26.

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1038/ncomms14977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414044PMC
April 2017

Analysis with the exome array identifies multiple new independent variants in lipid loci.

Hum Mol Genet 2016 09 27;25(18):4094-4106. Epub 2016 Jul 27.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK

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http://dx.doi.org/10.1093/hmg/ddw227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291227PMC
September 2016

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Authors:
Thomas W Winkler Anne E Justice Mariaelisa Graff Llilda Barata Mary F Feitosa Su Chu Jacek Czajkowski Tõnu Esko Tove Fall Tuomas O Kilpeläinen Yingchang Lu Reedik Mägi Evelin Mihailov Tune H Pers Sina Rüeger Alexander Teumer Georg B Ehret Teresa Ferreira Nancy L Heard-Costa Juha Karjalainen Vasiliki Lagou Anubha Mahajan Michael D Neinast Inga Prokopenko Jeannette Simino Tanya M Teslovich Rick Jansen Harm-Jan Westra Charles C White Devin Absher Tarunveer S Ahluwalia Shafqat Ahmad Eva Albrecht Alexessander Couto Alves Jennifer L Bragg-Gresham Anton J M de Craen Joshua C Bis Amélie Bonnefond Gabrielle Boucher Gemma Cadby Yu-Ching Cheng Charleston W K Chiang Graciela Delgado Ayse Demirkan Nicole Dueker Niina Eklund Gudny Eiriksdottir Joel Eriksson Bjarke Feenstra Krista Fischer Francesca Frau Tessel E Galesloot Frank Geller Anuj Goel Mathias Gorski Tanja B Grammer Stefan Gustafsson Saskia Haitjema Jouke-Jan Hottenga Jennifer E Huffman Anne U Jackson Kevin B Jacobs Åsa Johansson Marika Kaakinen Marcus E Kleber Jari Lahti Irene Mateo Leach Benjamin Lehne Youfang Liu Ken Sin Lo Mattias Lorentzon Jian'an Luan Pamela A F Madden Massimo Mangino Barbara McKnight Carolina Medina-Gomez Keri L Monda May E Montasser Gabriele Müller Martina Müller-Nurasyid Ilja M Nolte Kalliope Panoutsopoulou Laura Pascoe Lavinia Paternoster Nigel W Rayner Frida Renström Federica Rizzi Lynda M Rose Kathy A Ryan Perttu Salo Serena Sanna Hubert Scharnagl Jianxin Shi Albert Vernon Smith Lorraine Southam Alena Stančáková Valgerdur Steinthorsdottir Rona J Strawbridge Yun Ju Sung Ioanna Tachmazidou Toshiko Tanaka Gudmar Thorleifsson Stella Trompet Natalia Pervjakova Jonathan P Tyrer Liesbeth Vandenput Sander W van der Laan Nathalie van der Velde Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Efthymia Vlachopoulou Lindsay L Waite Sophie R Wang Zhaoming Wang Sarah H Wild Christina Willenborg James F Wilson Andrew Wong Jian Yang Loïc Yengo Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Ehm A Andersson Stephan J L Bakker Damiano Baldassarre Karina Banasik Matteo Barcella Cristina Barlassina Claire Bellis Paola Benaglio John Blangero Matthias Blüher Fabrice Bonnet Lori L Bonnycastle Heather A Boyd Marcel Bruinenberg Aron S Buchman Harry Campbell Yii-Der Ida Chen Peter S Chines Simone Claudi-Boehm John Cole Francis S Collins Eco J C de Geus Lisette C P G M de Groot Maria Dimitriou Jubao Duan Stefan Enroth Elodie Eury Aliki-Eleni Farmaki Nita G Forouhi Nele Friedrich Pablo V Gejman Bruna Gigante Nicola Glorioso Alan S Go Omri Gottesman Jürgen Gräßler Harald Grallert Niels Grarup Yu-Mei Gu Linda Broer Annelies C Ham Torben Hansen Tamara B Harris Catharina A Hartman Maija Hassinen Nicholas Hastie Andrew T Hattersley Andrew C Heath Anjali K Henders Dena Hernandez Hans Hillege Oddgeir Holmen Kees G Hovingh Jennie Hui Lise L Husemoen Nina Hutri-Kähönen Pirro G Hysi Thomas Illig Philip L De Jager Shapour Jalilzadeh Torben Jørgensen J Wouter Jukema Markus Juonala Stavroula Kanoni Maria Karaleftheri Kay Tee Khaw Leena Kinnunen Steven J Kittner Wolfgang Koenig Ivana Kolcic Peter Kovacs Nikolaj T Krarup Wolfgang Kratzer Janine Krüger Diana Kuh Meena Kumari Theodosios Kyriakou Claudia Langenberg Lars Lannfelt Chiara Lanzani Vaneet Lotay Lenore J Launer Karin Leander Jaana Lindström Allan Linneberg Yan-Ping Liu Stéphane Lobbens Robert Luben Valeriya Lyssenko Satu Männistö Patrik K Magnusson Wendy L McArdle Cristina Menni Sigrun Merger Lili Milani Grant W Montgomery Andrew P Morris Narisu Narisu Mari Nelis Ken K Ong Aarno Palotie Louis Pérusse Irene Pichler Maria G Pilia Anneli Pouta Myriam Rheinberger Rasmus Ribel-Madsen Marcus Richards Kenneth M Rice Treva K Rice Carlo Rivolta Veikko Salomaa Alan R Sanders Mark A Sarzynski Salome Scholtens Robert A Scott William R Scott Sylvain Sebert Sebanti Sengupta Bengt Sennblad Thomas Seufferlein Angela Silveira P Eline Slagboom Jan H Smit Thomas H Sparsø Kathleen Stirrups Ronald P Stolk Heather M Stringham Morris A Swertz Amy J Swift Ann-Christine Syvänen Sian-Tsung Tan Barbara Thorand Anke Tönjes Angelo Tremblay Emmanouil Tsafantakis Peter J van der Most Uwe Völker Marie-Claude Vohl Judith M Vonk Melanie Waldenberger Ryan W Walker Roman Wennauer Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Alan F Wright M Carola Zillikens Suzanne C van Dijk Natasja M van Schoor Folkert W Asselbergs Paul I W de Bakker Jacques S Beckmann John Beilby David A Bennett Richard N Bergman Sven Bergmann Carsten A Böger Bernhard O Boehm Eric Boerwinkle Dorret I Boomsma Stefan R Bornstein Erwin P Bottinger Claude Bouchard John C Chambers Stephen J Chanock Daniel I Chasman Francesco Cucca Daniele Cusi George Dedoussis Jeanette Erdmann Johan G Eriksson Denis A Evans Ulf de Faire Martin Farrall Luigi Ferrucci Ian Ford Lude Franke Paul W Franks Philippe Froguel Ron T Gansevoort Christian Gieger Henrik Grönberg Vilmundur Gudnason Ulf Gyllensten Per Hall Anders Hamsten Pim van der Harst Caroline Hayward Markku Heliövaara Christian Hengstenberg Andrew A Hicks Aroon Hingorani Albert Hofman Frank Hu Heikki V Huikuri Kristian Hveem Alan L James Joanne M Jordan Antti Jula Mika Kähönen Eero Kajantie Sekar Kathiresan Lambertus A L M Kiemeney Mika Kivimaki Paul B Knekt Heikki A Koistinen Jaspal S Kooner Seppo Koskinen Johanna Kuusisto Winfried Maerz Nicholas G Martin Markku Laakso Timo A Lakka Terho Lehtimäki Guillaume Lettre Douglas F Levinson Lars Lind Marja-Liisa Lokki Pekka Mäntyselkä Mads Melbye Andres Metspalu Braxton D Mitchell Frans L Moll Jeffrey C Murray Arthur W Musk Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Ben A Oostra Lyle J Palmer James S Pankow Gerard Pasterkamp Nancy L Pedersen Oluf Pedersen Brenda W Penninx Markus Perola Annette Peters Ozren Polašek Peter P Pramstaller Bruce M Psaty Lu Qi Thomas Quertermous Olli T Raitakari Tuomo Rankinen Rainer Rauramaa Paul M Ridker John D Rioux Fernando Rivadeneira Jerome I Rotter Igor Rudan Hester M den Ruijter Juha Saltevo Naveed Sattar Heribert Schunkert Peter E H Schwarz Alan R Shuldiner Juha Sinisalo Harold Snieder Thorkild I A Sørensen Tim D Spector Jan A Staessen Bandinelli Stefania Unnur Thorsteinsdottir Michael Stumvoll Jean-Claude Tardif Elena Tremoli Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa André L M Verbeek Sita H Vermeulen Jorma S Viikari Veronique Vitart Henry Völzke Peter Vollenweider Gérard Waeber Mark Walker Henri Wallaschofski Nicholas J Wareham Hugh Watkins Eleftheria Zeggini Aravinda Chakravarti Deborah J Clegg L Adrienne Cupples Penny Gordon-Larsen Cashell E Jaquish D C Rao Goncalo R Abecasis Themistocles L Assimes Inês Barroso Sonja I Berndt Michael Boehnke Panos Deloukas Caroline S Fox Leif C Groop David J Hunter Erik Ingelsson Robert C Kaplan Mark I McCarthy Karen L Mohlke Jeffrey R O'Connell David Schlessinger David P Strachan Kari Stefansson Cornelia M van Duijn Joel N Hirschhorn Cecilia M Lindgren Iris M Heid Kari E North Ingrid B Borecki Zoltán Kutalik Ruth J F Loos

PLoS Genet 2016 06 29;12(6):e1006166. Epub 2016 Jun 29.

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http://dx.doi.org/10.1371/journal.pgen.1006166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927064PMC
June 2016

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.

Authors:
Paul S de Vries Daniel I Chasman Maria Sabater-Lleal Ming-Huei Chen Jennifer E Huffman Maristella Steri Weihong Tang Alexander Teumer Riccardo E Marioni Vera Grossmann Jouke J Hottenga Stella Trompet Martina Müller-Nurasyid Jing Hua Zhao Jennifer A Brody Marcus E Kleber Xiuqing Guo Jie Jin Wang Paul L Auer John R Attia Lisa R Yanek Tarunveer S Ahluwalia Jari Lahti Cristina Venturini Toshiko Tanaka Lawrence F Bielak Peter K Joshi Ares Rocanin-Arjo Ivana Kolcic Pau Navarro Lynda M Rose Christopher Oldmeadow Helene Riess Johanna Mazur Saonli Basu Anuj Goel Qiong Yang Mohsen Ghanbari Gonneke Willemsen Ann Rumley Edoardo Fiorillo Anton J M de Craen Anne Grotevendt Robert Scott Kent D Taylor Graciela E Delgado Jie Yao Annette Kifley Charles Kooperberg Rehan Qayyum Lorna M Lopez Tina L Berentzen Katri Räikkönen Massimo Mangino Stefania Bandinelli Patricia A Peyser Sarah Wild David-Alexandre Trégouët Alan F Wright Jonathan Marten Tatijana Zemunik Alanna C Morrison Bengt Sennblad Geoffrey Tofler Moniek P M de Maat Eco J C de Geus Gordon D Lowe Magdalena Zoledziewska Naveed Sattar Harald Binder Uwe Völker Melanie Waldenberger Kay-Tee Khaw Barbara Mcknight Jie Huang Nancy S Jenny Elizabeth G Holliday Lihong Qi Mark G Mcevoy Diane M Becker John M Starr Antti-Pekka Sarin Pirro G Hysi Dena G Hernandez Min A Jhun Harry Campbell Anders Hamsten Fernando Rivadeneira Wendy L Mcardle P Eline Slagboom Tanja Zeller Wolfgang Koenig Bruce M Psaty Talin Haritunians Jingmin Liu Aarno Palotie André G Uitterlinden David J Stott Albert Hofman Oscar H Franco Ozren Polasek Igor Rudan Pierre-Emmanuel Morange James F Wilson Sharon L R Kardia Luigi Ferrucci Tim D Spector Johan G Eriksson Torben Hansen Ian J Deary Lewis C Becker Rodney J Scott Paul Mitchell Winfried März Nick J Wareham Annette Peters Andreas Greinacher Philipp S Wild J Wouter Jukema Dorret I Boomsma Caroline Hayward Francesco Cucca Russell Tracy Hugh Watkins Alex P Reiner Aaron R Folsom Paul M Ridker Christopher J O'Donnell Nicholas L Smith David P Strachan Abbas Dehghan

Hum Mol Genet 2016 Jan 10;25(2):358-70. Epub 2015 Nov 10.

Department of Epidemiology,

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http://dx.doi.org/10.1093/hmg/ddv454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715256PMC
January 2016

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Authors:
Kyle J Gaulton Teresa Ferreira Yeji Lee Anne Raimondo Reedik Mägi Michael E Reschen Anubha Mahajan Adam Locke N William Rayner Neil Robertson Robert A Scott Inga Prokopenko Laura J Scott Todd Green Thomas Sparso Dorothee Thuillier Loic Yengo Harald Grallert Simone Wahl Mattias Frånberg Rona J Strawbridge Hans Kestler Himanshu Chheda Lewin Eisele Stefan Gustafsson Valgerdur Steinthorsdottir Gudmar Thorleifsson Lu Qi Lennart C Karssen Elisabeth M van Leeuwen Sara M Willems Man Li Han Chen Christian Fuchsberger Phoenix Kwan Clement Ma Michael Linderman Yingchang Lu Soren K Thomsen Jana K Rundle Nicola L Beer Martijn van de Bunt Anil Chalisey Hyun Min Kang Benjamin F Voight Gonçalo R Abecasis Peter Almgren Damiano Baldassarre Beverley Balkau Rafn Benediktsson Matthias Blüher Heiner Boeing Lori L Bonnycastle Erwin P Bottinger Noël P Burtt Jason Carey Guillaume Charpentier Peter S Chines Marilyn C Cornelis David J Couper Andrew T Crenshaw Rob M van Dam Alex S F Doney Mozhgan Dorkhan Sarah Edkins Johan G Eriksson Tonu Esko Elodie Eury João Fadista Jason Flannick Pierre Fontanillas Caroline Fox Paul W Franks Karl Gertow Christian Gieger Bruna Gigante Omri Gottesman George B Grant Niels Grarup Christopher J Groves Maija Hassinen Christian T Have Christian Herder Oddgeir L Holmen Astradur B Hreidarsson Steve E Humphries David J Hunter Anne U Jackson Anna Jonsson Marit E Jørgensen Torben Jørgensen Wen-Hong L Kao Nicola D Kerrison Leena Kinnunen Norman Klopp Augustine Kong Peter Kovacs Peter Kraft Jasmina Kravic Cordelia Langford Karin Leander Liming Liang Peter Lichtner Cecilia M Lindgren Eero Lindholm Allan Linneberg Ching-Ti Liu Stéphane Lobbens Jian'an Luan Valeriya Lyssenko Satu Männistö Olga McLeod Julia Meyer Evelin Mihailov Ghazala Mirza Thomas W Mühleisen Martina Müller-Nurasyid Carmen Navarro Markus M Nöthen Nikolay N Oskolkov Katharine R Owen Domenico Palli Sonali Pechlivanis Leena Peltonen John R B Perry Carl G P Platou Michael Roden Douglas Ruderfer Denis Rybin Yvonne T van der Schouw Bengt Sennblad Gunnar Sigurðsson Alena Stančáková Gerald Steinbach Petter Storm Konstantin Strauch Heather M Stringham Qi Sun Barbara Thorand Emmi Tikkanen Anke Tonjes Joseph Trakalo Elena Tremoli Tiinamaija Tuomi Roman Wennauer Steven Wiltshire Andrew R Wood Eleftheria Zeggini Ian Dunham Ewan Birney Lorenzo Pasquali Jorge Ferrer Ruth J F Loos Josée Dupuis Jose C Florez Eric Boerwinkle James S Pankow Cornelia van Duijn Eric Sijbrands James B Meigs Frank B Hu Unnur Thorsteinsdottir Kari Stefansson Timo A Lakka Rainer Rauramaa Michael Stumvoll Nancy L Pedersen Lars Lind Sirkka M Keinanen-Kiukaanniemi Eeva Korpi-Hyövälti Timo E Saaristo Juha Saltevo Johanna Kuusisto Markku Laakso Andres Metspalu Raimund Erbel Karl-Heinz Jöcke Susanne Moebus Samuli Ripatti Veikko Salomaa Erik Ingelsson Bernhard O Boehm Richard N Bergman Francis S Collins Karen L Mohlke Heikki Koistinen Jaakko Tuomilehto Kristian Hveem Inger Njølstad Panagiotis Deloukas Peter J Donnelly Timothy M Frayling Andrew T Hattersley Ulf de Faire Anders Hamsten Thomas Illig Annette Peters Stephane Cauchi Rob Sladek Philippe Froguel Torben Hansen Oluf Pedersen Andrew D Morris Collin N A Palmer Sekar Kathiresan Olle Melander Peter M Nilsson Leif C Groop Inês Barroso Claudia Langenberg Nicholas J Wareham Christopher A O'Callaghan Anna L Gloyn David Altshuler Michael Boehnke Tanya M Teslovich Mark I McCarthy Andrew P Morris

Nat Genet 2015 Dec 9;47(12):1415-25. Epub 2015 Nov 9.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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December 2015

Integrating Sequence Evolution into Probabilistic Orthology Analysis.

Syst Biol 2015 Nov 30;64(6):969-82. Epub 2015 Jun 30.

School of Computer Science and Communication, Science for Life Laboratory, Swedish e-Science Research Center (SeRC), KTH Royal Institute of Technology, Stockholm, Sweden;

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November 2015

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Authors:
Thomas W Winkler Anne E Justice Mariaelisa Graff Llilda Barata Mary F Feitosa Su Chu Jacek Czajkowski Tõnu Esko Tove Fall Tuomas O Kilpeläinen Yingchang Lu Reedik Mägi Evelin Mihailov Tune H Pers Sina Rüeger Alexander Teumer Georg B Ehret Teresa Ferreira Nancy L Heard-Costa Juha Karjalainen Vasiliki Lagou Anubha Mahajan Michael D Neinast Inga Prokopenko Jeannette Simino Tanya M Teslovich Rick Jansen Harm-Jan Westra Charles C White Devin Absher Tarunveer S Ahluwalia Shafqat Ahmad Eva Albrecht Alexessander Couto Alves Jennifer L Bragg-Gresham Anton J M de Craen Joshua C Bis Amélie Bonnefond Gabrielle Boucher Gemma Cadby Yu-Ching Cheng Charleston W K Chiang Graciela Delgado Ayse Demirkan Nicole Dueker Niina Eklund Gudny Eiriksdottir Joel Eriksson Bjarke Feenstra Krista Fischer Francesca Frau Tessel E Galesloot Frank Geller Anuj Goel Mathias Gorski Tanja B Grammer Stefan Gustafsson Saskia Haitjema Jouke-Jan Hottenga Jennifer E Huffman Anne U Jackson Kevin B Jacobs Åsa Johansson Marika Kaakinen Marcus E Kleber Jari Lahti Irene Mateo Leach Benjamin Lehne Youfang Liu Ken Sin Lo Mattias Lorentzon Jian'an Luan Pamela A F Madden Massimo Mangino Barbara McKnight Carolina Medina-Gomez Keri L Monda May E Montasser Gabriele Müller Martina Müller-Nurasyid Ilja M Nolte Kalliope Panoutsopoulou Laura Pascoe Lavinia Paternoster Nigel W Rayner Frida Renström Federica Rizzi Lynda M Rose Kathy A Ryan Perttu Salo Serena Sanna Hubert Scharnagl Jianxin Shi Albert Vernon Smith Lorraine Southam Alena Stančáková Valgerdur Steinthorsdottir Rona J Strawbridge Yun Ju Sung Ioanna Tachmazidou Toshiko Tanaka Gudmar Thorleifsson Stella Trompet Natalia Pervjakova Jonathan P Tyrer Liesbeth Vandenput Sander W van der Laan Nathalie van der Velde Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Efthymia Vlachopoulou Lindsay L Waite Sophie R Wang Zhaoming Wang Sarah H Wild Christina Willenborg James F Wilson Andrew Wong Jian Yang Loïc Yengo Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Ehm A Andersson Stephan J L Bakker Damiano Baldassarre Karina Banasik Matteo Barcella Cristina Barlassina Claire Bellis Paola Benaglio John Blangero Matthias Blüher Fabrice Bonnet Lori L Bonnycastle Heather A Boyd Marcel Bruinenberg Aron S Buchman Harry Campbell Yii-Der Ida Chen Peter S Chines Simone Claudi-Boehm John Cole Francis S Collins Eco J C de Geus Lisette C P G M de Groot Maria Dimitriou Jubao Duan Stefan Enroth Elodie Eury Aliki-Eleni Farmaki Nita G Forouhi Nele Friedrich Pablo V Gejman Bruna Gigante Nicola Glorioso Alan S Go Omri Gottesman Jürgen Gräßler Harald Grallert Niels Grarup Yu-Mei Gu Linda Broer Annelies C Ham Torben Hansen Tamara B Harris Catharina A Hartman Maija Hassinen Nicholas Hastie Andrew T Hattersley Andrew C Heath Anjali K Henders Dena Hernandez Hans Hillege Oddgeir Holmen Kees G Hovingh Jennie Hui Lise L Husemoen Nina Hutri-Kähönen Pirro G Hysi Thomas Illig Philip L De Jager Shapour Jalilzadeh Torben Jørgensen J Wouter Jukema Markus Juonala Stavroula Kanoni Maria Karaleftheri Kay Tee Khaw Leena Kinnunen Steven J Kittner Wolfgang Koenig Ivana Kolcic Peter Kovacs Nikolaj T Krarup Wolfgang Kratzer Janine Krüger Diana Kuh Meena Kumari Theodosios Kyriakou Claudia Langenberg Lars Lannfelt Chiara Lanzani Vaneet Lotay Lenore J Launer Karin Leander Jaana Lindström Allan Linneberg Yan-Ping Liu Stéphane Lobbens Robert Luben Valeriya Lyssenko Satu Männistö Patrik K Magnusson Wendy L McArdle Cristina Menni Sigrun Merger Lili Milani Grant W Montgomery Andrew P Morris Narisu Narisu Mari Nelis Ken K Ong Aarno Palotie Louis Pérusse Irene Pichler Maria G Pilia Anneli Pouta Myriam Rheinberger Rasmus Ribel-Madsen Marcus Richards Kenneth M Rice Treva K Rice Carlo Rivolta Veikko Salomaa Alan R Sanders Mark A Sarzynski Salome Scholtens Robert A Scott William R Scott Sylvain Sebert Sebanti Sengupta Bengt Sennblad Thomas Seufferlein Angela Silveira P Eline Slagboom Jan H Smit Thomas H Sparsø Kathleen Stirrups Ronald P Stolk Heather M Stringham Morris A Swertz Amy J Swift Ann-Christine Syvänen Sian-Tsung Tan Barbara Thorand Anke Tönjes Angelo Tremblay Emmanouil Tsafantakis Peter J van der Most Uwe Völker Marie-Claude Vohl Judith M Vonk Melanie Waldenberger Ryan W Walker Roman Wennauer Elisabeth Widén Gonneke Willemsen Tom Wilsgaard Alan F Wright M Carola Zillikens Suzanne C van Dijk Natasja M van Schoor Folkert W Asselbergs Paul I W de Bakker Jacques S Beckmann John Beilby David A Bennett Richard N Bergman Sven Bergmann Carsten A Böger Bernhard O Boehm Eric Boerwinkle Dorret I Boomsma Stefan R Bornstein Erwin P Bottinger Claude Bouchard John C Chambers Stephen J Chanock Daniel I Chasman Francesco Cucca Daniele Cusi George Dedoussis Jeanette Erdmann Johan G Eriksson Denis A Evans Ulf de Faire Martin Farrall Luigi Ferrucci Ian Ford Lude Franke Paul W Franks Philippe Froguel Ron T Gansevoort Christian Gieger Henrik Grönberg Vilmundur Gudnason Ulf Gyllensten Per Hall Anders Hamsten Pim van der Harst Caroline Hayward Markku Heliövaara Christian Hengstenberg Andrew A Hicks Aroon Hingorani Albert Hofman Frank Hu Heikki V Huikuri Kristian Hveem Alan L James Joanne M Jordan Antti Jula Mika Kähönen Eero Kajantie Sekar Kathiresan Lambertus A L M Kiemeney Mika Kivimaki Paul B Knekt Heikki A Koistinen Jaspal S Kooner Seppo Koskinen Johanna Kuusisto Winfried Maerz Nicholas G Martin Markku Laakso Timo A Lakka Terho Lehtimäki Guillaume Lettre Douglas F Levinson Lars Lind Marja-Liisa Lokki Pekka Mäntyselkä Mads Melbye Andres Metspalu Braxton D Mitchell Frans L Moll Jeffrey C Murray Arthur W Musk Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Ben A Oostra Lyle J Palmer James S Pankow Gerard Pasterkamp Nancy L Pedersen Oluf Pedersen Brenda W Penninx Markus Perola Annette Peters Ozren Polašek Peter P Pramstaller Bruce M Psaty Lu Qi Thomas Quertermous Olli T Raitakari Tuomo Rankinen Rainer Rauramaa Paul M Ridker John D Rioux Fernando Rivadeneira Jerome I Rotter Igor Rudan Hester M den Ruijter Juha Saltevo Naveed Sattar Heribert Schunkert Peter E H Schwarz Alan R Shuldiner Juha Sinisalo Harold Snieder Thorkild I A Sørensen Tim D Spector Jan A Staessen Bandinelli Stefania Unnur Thorsteinsdottir Michael Stumvoll Jean-Claude Tardif Elena Tremoli Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa André L M Verbeek Sita H Vermeulen Jorma S Viikari Veronique Vitart Henry Völzke Peter Vollenweider Gérard Waeber Mark Walker Henri Wallaschofski Nicholas J Wareham Hugh Watkins Eleftheria Zeggini Aravinda Chakravarti Deborah J Clegg L Adrienne Cupples Penny Gordon-Larsen Cashell E Jaquish D C Rao Goncalo R Abecasis Themistocles L Assimes Inês Barroso Sonja I Berndt Michael Boehnke Panos Deloukas Caroline S Fox Leif C Groop David J Hunter Erik Ingelsson Robert C Kaplan Mark I McCarthy Karen L Mohlke Jeffrey R O'Connell David Schlessinger David P Strachan Kari Stefansson Cornelia M van Duijn Joel N Hirschhorn Cecilia M Lindgren Iris M Heid Kari E North Ingrid B Borecki Zoltán Kutalik Ruth J F Loos

PLoS Genet 2015 Oct 1;11(10):e1005378. Epub 2015 Oct 1.

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591371PMC
October 2015

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.

Authors:
Jens Baumert Jie Huang Barbara McKnight Maria Sabater-Lleal Maristella Steri Audrey Y Chu Stella Trompet Lorna M Lopez Myriam Fornage Alexander Teumer Weihong Tang Alicja R Rudnicka Anders Mälarstig Jouke-Jan Hottenga Maryam Kavousi Jari Lahti Toshiko Tanaka Caroline Hayward Jennifer E Huffman Pierre-Emmanuel Morange Lynda M Rose Saonli Basu Ann Rumley David J Stott Brendan M Buckley Anton J M de Craen Serena Sanna Marco Masala Reiner Biffar Georg Homuth Angela Silveira Bengt Sennblad Anuj Goel Hugh Watkins Martina Müller-Nurasyid Regina Rückerl Kent Taylor Ming-Huei Chen Eco J C de Geus Albert Hofman Jacqueline C M Witteman Moniek P M de Maat Aarno Palotie Gail Davies David S Siscovick Ivana Kolcic Sarah H Wild Jaejoon Song Wendy L McArdle Ian Ford Naveed Sattar David Schlessinger Anne Grotevendt Maria Grazia Franzosi Thomas Illig Melanie Waldenberger Thomas Lumley Geoffrey H Tofler Gonneke Willemsen André G Uitterlinden Fernando Rivadeneira Katri Räikkönen Daniel I Chasman Aaron R Folsom Gordon D Lowe Rudi G J Westendorp P Eline Slagboom Francesco Cucca Henri Wallaschofski Rona J Strawbridge Udo Seedorf Wolfgang Koenig Joshua C Bis Kenneth J Mukamal Jenny van Dongen Elisabeth Widen Oscar H Franco John M Starr Kiang Liu Luigi Ferrucci Ozren Polasek James F Wilson Tiphaine Oudot-Mellakh Harry Campbell Pau Navarro Stefania Bandinelli Johan Eriksson Dorret I Boomsma Abbas Dehghan Robert Clarke Anders Hamsten Eric Boerwinkle J Wouter Jukema Silvia Naitza Paul M Ridker Henry Völzke Ian J Deary Alexander P Reiner David-Alexandre Trégouët Christopher J O'Donnell David P Strachan Annette Peters Nicholas L Smith

PLoS One 2014 31;9(12):e111156. Epub 2014 Dec 31.

Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, Finland; Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America; Seattle Epidemiologic Research & Information Center, Veterans Affairs Office of Research & Development, Seattle, Washington, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281156PMC
September 2015

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF.

Blood 2015 Sep 23;126(11):e19-29. Epub 2015 Jun 23.

Department of Epidemiology, and Group Health Research Institute, Group Health Cooperative, Seattle, WA; Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development, Seattle, WA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566813PMC
September 2015

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests.

PLoS Genet 2015 Sep 24;11(9):e1005502. Epub 2015 Sep 24.

Atherosclerosis Research Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden; Science for Life Laboratory, Stockholm, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581725PMC
September 2015

Directional dominance on stature and cognition in diverse human populations.

Authors:
Peter K Joshi Tonu Esko Hannele Mattsson Niina Eklund Ilaria Gandin Teresa Nutile Anne U Jackson Claudia Schurmann Albert V Smith Weihua Zhang Yukinori Okada Alena Stančáková Jessica D Faul Wei Zhao Traci M Bartz Maria Pina Concas Nora Franceschini Stefan Enroth Veronique Vitart Stella Trompet Xiuqing Guo Daniel I Chasman Jeffery R O'Connel Tanguy Corre Suraj S Nongmaithem Yuning Chen Massimo Mangino Daniela Ruggiero Michela Traglia Aliki-Eleni Farmaki Tim Kacprowski Andrew Bjonnes Ashley van der Spek Ying Wu Anil K Giri Lisa R Yanek Lihua Wang Edith Hofer Cornelius A Rietveld Olga McLeod Marilyn C Cornelis Cristian Pattaro Niek Verweij Clemens Baumbach Abdel Abdellaoui Helen R Warren Dragana Vuckovic Hao Mei Claude Bouchard John R B Perry Stefania Cappellani Saira S Mirza Miles C Benton Ulrich Broeckel Sarah E Medland Penelope A Lind Giovanni Malerba Alexander Drong Loic Yengo Lawrence F Bielak Degui Zhi Peter J van der Most Daniel Shriner Reedik Mägi Gibran Hemani Tugce Karaderi Zhaoming Wang Tian Liu Ilja Demuth Jing Hua Zhao Weihua Meng Lazaros Lataniotis Sander W van der Laan Jonathan P Bradfield Andrew R Wood Amelie Bonnefond Tarunveer S Ahluwalia Leanne M Hall Erika Salvi Seyhan Yazar Lisbeth Carstensen Hugoline G de Haan Mark Abney Uzma Afzal Matthew A Allison Najaf Amin Folkert W Asselbergs Stephan J L Bakker R Graham Barr Sebastian E Baumeister Daniel J Benjamin Sven Bergmann Eric Boerwinkle Erwin P Bottinger Archie Campbell Aravinda Chakravarti Yingleong Chan Stephen J Chanock Constance Chen Y-D Ida Chen Francis S Collins John Connell Adolfo Correa L Adrienne Cupples George Davey Smith Gail Davies Marcus Dörr Georg Ehret Stephen B Ellis Bjarke Feenstra Mary F Feitosa Ian Ford Caroline S Fox Timothy M Frayling Nele Friedrich Frank Geller Generation Scotland Irina Gillham-Nasenya Omri Gottesman Misa Graff Francine Grodstein Charles Gu Chris Haley Christopher J Hammond Sarah E Harris Tamara B Harris Nicholas D Hastie Nancy L Heard-Costa Kauko Heikkilä Lynne J Hocking Georg Homuth Jouke-Jan Hottenga Jinyan Huang Jennifer E Huffman Pirro G Hysi M Arfan Ikram Erik Ingelsson Anni Joensuu Åsa Johansson Pekka Jousilahti J Wouter Jukema Mika Kähönen Yoichiro Kamatani Stavroula Kanoni Shona M Kerr Nazir M Khan Philipp Koellinger Heikki A Koistinen Manraj K Kooner Michiaki Kubo Johanna Kuusisto Jari Lahti Lenore J Launer Rodney A Lea Benjamin Lehne Terho Lehtimäki David C M Liewald Lars Lind Marie Loh Marja-Liisa Lokki Stephanie J London Stephanie J Loomis Anu Loukola Yingchang Lu Thomas Lumley Annamari Lundqvist Satu Männistö Pedro Marques-Vidal Corrado Masciullo Angela Matchan Rasika A Mathias Koichi Matsuda James B Meigs Christa Meisinger Thomas Meitinger Cristina Menni Frank D Mentch Evelin Mihailov Lili Milani May E Montasser Grant W Montgomery Alanna Morrison Richard H Myers Rajiv Nadukuru Pau Navarro Mari Nelis Markku S Nieminen Ilja M Nolte George T O'Connor Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas James S Pankow Inga Patarcic Francesca Pavani Patricia A Peyser Kirsi Pietilainen Neil Poulter Inga Prokopenko Sarju Ralhan Paul Redmond Stephen S Rich Harri Rissanen Antonietta Robino Lynda M Rose Richard Rose Cinzia Sala Babatunde Salako Veikko Salomaa Antti-Pekka Sarin Richa Saxena Helena Schmidt Laura J Scott William R Scott Bengt Sennblad Sudha Seshadri Peter Sever Smeeta Shrestha Blair H Smith Jennifer A Smith Nicole Soranzo Nona Sotoodehnia Lorraine Southam Alice V Stanton Maria G Stathopoulou Konstantin Strauch Rona J Strawbridge Matthew J Suderman Nikhil Tandon Sian-Tsun Tang Kent D Taylor Bamidele O Tayo Anna Maria Töglhofer Maciej Tomaszewski Natalia Tšernikova Jaakko Tuomilehto Andre G Uitterlinden Dhananjay Vaidya Astrid van Hylckama Vlieg Jessica van Setten Tuula Vasankari Sailaja Vedantam Efthymia Vlachopoulou Diego Vozzi Eero Vuoksimaa Melanie Waldenberger Erin B Ware William Wentworth-Shields John B Whitfield Sarah Wild Gonneke Willemsen Chittaranjan S Yajnik Jie Yao Gianluigi Zaza Xiaofeng Zhu The BioBank Japan Project Rany M Salem Mads Melbye Hans Bisgaard Nilesh J Samani Daniele Cusi David A Mackey Richard S Cooper Philippe Froguel Gerard Pasterkamp Struan F A Grant Hakon Hakonarson Luigi Ferrucci Robert A Scott Andrew D Morris Colin N A Palmer George Dedoussis Panos Deloukas Lars Bertram Ulman Lindenberger Sonja I Berndt Cecilia M Lindgren Nicholas J Timpson Anke Tönjes Patricia B Munroe Thorkild I A Sørensen Charles N Rotimi Donna K Arnett Albertine J Oldehinkel Sharon L R Kardia Beverley Balkau Giovanni Gambaro Andrew P Morris Johan G Eriksson Margie J Wright Nicholas G Martin Steven C Hunt John M Starr Ian J Deary Lyn R Griffiths Henning Tiemeier Nicola Pirastu Jaakko Kaprio Nicholas J Wareham Louis Pérusse James G Wilson Giorgia Girotto Mark J Caulfield Olli Raitakari Dorret I Boomsma Christian Gieger Pim van der Harst Andrew A Hicks Peter Kraft Juha Sinisalo Paul Knekt Magnus Johannesson Patrik K E Magnusson Anders Hamsten Reinhold Schmidt Ingrid B Borecki Erkki Vartiainen Diane M Becker Dwaipayan Bharadwaj Karen L Mohlke Michael Boehnke Cornelia M van Duijn Dharambir K Sanghera Alexander Teumer Eleftheria Zeggini Andres Metspalu Paolo Gasparini Sheila Ulivi Carole Ober Daniela Toniolo Igor Rudan David J Porteous Marina Ciullo Tim D Spector Caroline Hayward Josée Dupuis Ruth J F Loos Alan F Wright Giriraj R Chandak Peter Vollenweider Alan Shuldiner Paul M Ridker Jerome I Rotter Naveed Sattar Ulf Gyllensten Kari E North Mario Pirastu Bruce M Psaty David R Weir Markku Laakso Vilmundur Gudnason Atsushi Takahashi John C Chambers Jaspal S Kooner David P Strachan Harry Campbell Joel N Hirschhorn Markus Perola Ozren Polašek James F Wilson

Nature 2015 Jul 1;523(7561):459-462. Epub 2015 Jul 1.

Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516141PMC
July 2015

New genetic loci link adipose and insulin biology to body fat distribution.

Authors:
Dmitry Shungin Thomas W Winkler Damien C Croteau-Chonka Teresa Ferreira Adam E Locke Reedik Mägi Rona J Strawbridge Tune H Pers Krista Fischer Anne E Justice Tsegaselassie Workalemahu Joseph M W Wu Martin L Buchkovich Nancy L Heard-Costa Tamara S Roman Alexander W Drong Ci Song Stefan Gustafsson Felix R Day Tonu Esko Tove Fall Zoltán Kutalik Jian'an Luan Joshua C Randall André Scherag Sailaja Vedantam Andrew R Wood Jin Chen Rudolf Fehrmann Juha Karjalainen Bratati Kahali Ching-Ti Liu Ellen M Schmidt Devin Absher Najaf Amin Denise Anderson Marian Beekman Jennifer L Bragg-Gresham Steven Buyske Ayse Demirkan Georg B Ehret Mary F Feitosa Anuj Goel Anne U Jackson Toby Johnson Marcus E Kleber Kati Kristiansson Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Cameron D Palmer Dorota Pasko Sonali Pechlivanis Marjolein J Peters Inga Prokopenko Alena Stančáková Yun Ju Sung Toshiko Tanaka Alexander Teumer Jana V Van Vliet-Ostaptchouk Loïc Yengo Weihua Zhang Eva Albrecht Johan Ärnlöv Gillian M Arscott Stefania Bandinelli Amy Barrett Claire Bellis Amanda J Bennett Christian Berne Matthias Blüher Stefan Böhringer Fabrice Bonnet Yvonne Böttcher Marcel Bruinenberg Delia B Carba Ida H Caspersen Robert Clarke E Warwick Daw Joris Deelen Ewa Deelman Graciela Delgado Alex Sf Doney Niina Eklund Michael R Erdos Karol Estrada Elodie Eury Nele Friedrich Melissa E Garcia Vilmantas Giedraitis Bruna Gigante Alan S Go Alain Golay Harald Grallert Tanja B Grammer Jürgen Gräßler Jagvir Grewal Christopher J Groves Toomas Haller Goran Hallmans Catharina A Hartman Maija Hassinen Caroline Hayward Kauko Heikkilä Karl-Heinz Herzig Quinta Helmer Hans L Hillege Oddgeir Holmen Steven C Hunt Aaron Isaacs Till Ittermann Alan L James Ingegerd Johansson Thorhildur Juliusdottir Ioanna-Panagiota Kalafati Leena Kinnunen Wolfgang Koenig Ishminder K Kooner Wolfgang Kratzer Claudia Lamina Karin Leander Nanette R Lee Peter Lichtner Lars Lind Jaana Lindström Stéphane Lobbens Mattias Lorentzon François Mach Patrik Ke Magnusson Anubha Mahajan Wendy L McArdle Cristina Menni Sigrun Merger Evelin Mihailov Lili Milani Rebecca Mills Alireza Moayyeri Keri L Monda Simon P Mooijaart Thomas W Mühleisen Antonella Mulas Gabriele Müller Martina Müller-Nurasyid Ramaiah Nagaraja Michael A Nalls Narisu Narisu Nicola Glorioso Ilja M Nolte Matthias Olden Nigel W Rayner Frida Renstrom Janina S Ried Neil R Robertson Lynda M Rose Serena Sanna Hubert Scharnagl Salome Scholtens Bengt Sennblad Thomas Seufferlein Colleen M Sitlani Albert Vernon Smith Kathleen Stirrups Heather M Stringham Johan Sundström Morris A Swertz Amy J Swift Ann-Christine Syvänen Bamidele O Tayo Barbara Thorand Gudmar Thorleifsson Andreas Tomaschitz Chiara Troffa Floor Va van Oort Niek Verweij Judith M Vonk Lindsay L Waite Roman Wennauer Tom Wilsgaard Mary K Wojczynski Andrew Wong Qunyuan Zhang Jing Hua Zhao Eoin P Brennan Murim Choi Per Eriksson Lasse Folkersen Anders Franco-Cereceda Ali G Gharavi Åsa K Hedman Marie-France Hivert Jinyan Huang Stavroula Kanoni Fredrik Karpe Sarah Keildson Krzysztof Kiryluk Liming Liang Richard P Lifton Baoshan Ma Amy J McKnight Ruth McPherson Andres Metspalu Josine L Min Miriam F Moffatt Grant W Montgomery Joanne M Murabito George Nicholson Dale R Nyholt Christian Olsson John Rb Perry Eva Reinmaa Rany M Salem Niina Sandholm Eric E Schadt Robert A Scott Lisette Stolk Edgar E Vallejo Harm-Jan Westra Krina T Zondervan Philippe Amouyel Dominique Arveiler Stephan Jl Bakker John Beilby Richard N Bergman John Blangero Morris J Brown Michel Burnier Harry Campbell Aravinda Chakravarti Peter S Chines Simone Claudi-Boehm Francis S Collins Dana C Crawford John Danesh Ulf de Faire Eco Jc de Geus Marcus Dörr Raimund Erbel Johan G Eriksson Martin Farrall Ele Ferrannini Jean Ferrières Nita G Forouhi Terrence Forrester Oscar H Franco Ron T Gansevoort Christian Gieger Vilmundur Gudnason Christopher A Haiman Tamara B Harris Andrew T Hattersley Markku Heliövaara Andrew A Hicks Aroon D Hingorani Wolfgang Hoffmann Albert Hofman Georg Homuth Steve E Humphries Elina Hyppönen Thomas Illig Marjo-Riitta Jarvelin Berit Johansen Pekka Jousilahti Antti M Jula Jaakko Kaprio Frank Kee Sirkka M Keinanen-Kiukaanniemi Jaspal S Kooner Charles Kooperberg Peter Kovacs Aldi T Kraja Meena Kumari Kari Kuulasmaa Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Valeriya Lyssenko Satu Männistö André Marette Tara C Matise Colin A McKenzie Barbara McKnight Arthur W Musk Stefan Möhlenkamp Andrew D Morris Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Lyle J Palmer Brenda W Penninx Annette Peters Peter P Pramstaller Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Paul M Ridker Marylyn D Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Peter Eh Schwarz Alan R Shuldiner Jan A Staessen Valgerdur Steinthorsdottir Ronald P Stolk Konstantin Strauch Anke Tönjes Angelo Tremblay Elena Tremoli Marie-Claude Vohl Uwe Völker Peter Vollenweider James F Wilson Jacqueline C Witteman Linda S Adair Murielle Bochud Bernhard O Boehm Stefan R Bornstein Claude Bouchard Stéphane Cauchi Mark J Caulfield John C Chambers Daniel I Chasman Richard S Cooper George Dedoussis Luigi Ferrucci Philippe Froguel Hans-Jörgen Grabe Anders Hamsten Jennie Hui Kristian Hveem Karl-Heinz Jöckel Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Winfried März Patricia B Munroe Inger Njølstad Ben A Oostra Colin Na Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Chris Power Thomas Quertermous Rainer Rauramaa Fernando Rivadeneira Timo E Saaristo Danish Saleheen Juha Sinisalo P Eline Slagboom Harold Snieder Tim D Spector Kari Stefansson Michael Stumvoll Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Giovanni Veronesi Mark Walker Nicholas J Wareham Hugh Watkins H-Erich Wichmann Goncalo R Abecasis Themistocles L Assimes Sonja I Berndt Michael Boehnke Ingrid B Borecki Panos Deloukas Lude Franke Timothy M Frayling Leif C Groop David J Hunter Robert C Kaplan Jeffrey R O'Connell Lu Qi David Schlessinger David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Cristen J Willer Peter M Visscher Jian Yang Joel N Hirschhorn M Carola Zillikens Mark I McCarthy Elizabeth K Speliotes Kari E North Caroline S Fox Inês Barroso Paul W Franks Erik Ingelsson Iris M Heid Ruth Jf Loos L Adrienne Cupples Andrew P Morris Cecilia M Lindgren Karen L Mohlke

Nature 2015 Feb;518(7538):187-196

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

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February 2015

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Authors:
Daniel I Swerdlow David Preiss Karoline B Kuchenbaecker Michael V Holmes Jorgen E L Engmann Tina Shah Reecha Sofat Stefan Stender Paul C D Johnson Robert A Scott Maarten Leusink Niek Verweij Stephen J Sharp Yiran Guo Claudia Giambartolomei Christina Chung Anne Peasey Antoinette Amuzu KaWah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos Yun R Li Gordon Lowe John Gallacher Marlene C W Stewart Ioanna Tzoulaki Sarah G Buxbaum Daphne L van der A Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Urszula Stepaniak Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Fabrizio Veglia Ian Ford J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Pim A de Jong Ale Algra Wilko Spiering Anke H Maitland-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Charles B Eaton Jennifer G Robinson David Duggan John Kjekshus John R Downs Antonio M Gotto Anthony C Keech Roberto Marchioli Gianni Tognoni Peter S Sever Neil R Poulter David D Waters Terje R Pedersen Pierre Amarenco Haruo Nakamura John J V McMurray James D Lewsey Daniel I Chasman Paul M Ridker Aldo P Maggioni Luigi Tavazzi Kausik K Ray Sreenivasa Rao Kondapally Seshasai JoAnn E Manson Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Pamela J Schreiner Myriam Fornage David S Siscovick Mary Cushman Meena Kumari Nick J Wareham W M Monique Verschuren Susan Redline Sanjay R Patel John C Whittaker Anders Hamsten Joseph A Delaney Caroline Dale Tom R Gaunt Andrew Wong Diana Kuh Rebecca Hardy Sekar Kathiresan Berta A Castillo Pim van der Harst Eric J Brunner Anne Tybjaerg-Hansen Michael G Marmot Ronald M Krauss Michael Tsai Josef Coresh Ronald C Hoogeveen Bruce M Psaty Leslie A Lange Hakon Hakonarson Frank Dudbridge Steve E Humphries Philippa J Talmud Mika Kivimäki Nicholas J Timpson Claudia Langenberg Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Alex P Reiner Brendan J Keating Aroon D Hingorani Naveed Sattar

Lancet 2015 Jan 24;385(9965):351-61. Epub 2014 Sep 24.

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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January 2015

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.

Authors:
Jennifer Wessel Audrey Y Chu Sara M Willems Shuai Wang Hanieh Yaghootkar Jennifer A Brody Marco Dauriz Marie-France Hivert Sridharan Raghavan Leonard Lipovich Bertha Hidalgo Keolu Fox Jennifer E Huffman Ping An Yingchang Lu Laura J Rasmussen-Torvik Niels Grarup Margaret G Ehm Li Li Abigail S Baldridge Alena Stančáková Ravinder Abrol Céline Besse Anne Boland Jette Bork-Jensen Myriam Fornage Daniel F Freitag Melissa E Garcia Xiuqing Guo Kazuo Hara Aaron Isaacs Johanna Jakobsdottir Leslie A Lange Jill C Layton Man Li Jing Hua Zhao Karina Meidtner Alanna C Morrison Mike A Nalls Marjolein J Peters Maria Sabater-Lleal Claudia Schurmann Angela Silveira Albert V Smith Lorraine Southam Marcus H Stoiber Rona J Strawbridge Kent D Taylor Tibor V Varga Kristine H Allin Najaf Amin Jennifer L Aponte Tin Aung Caterina Barbieri Nathan A Bihlmeyer Michael Boehnke Cristina Bombieri Donald W Bowden Sean M Burns Yuning Chen Yii-DerI Chen Ching-Yu Cheng Adolfo Correa Jacek Czajkowski Abbas Dehghan Georg B Ehret Gudny Eiriksdottir Stefan A Escher Aliki-Eleni Farmaki Mattias Frånberg Giovanni Gambaro Franco Giulianini William A Goddard Anuj Goel Omri Gottesman Megan L Grove Stefan Gustafsson Yang Hai Göran Hallmans Jiyoung Heo Per Hoffmann Mohammad K Ikram Richard A Jensen Marit E Jørgensen Torben Jørgensen Maria Karaleftheri Chiea C Khor Andrea Kirkpatrick Aldi T Kraja Johanna Kuusisto Ethan M Lange I T Lee Wen-Jane Lee Aaron Leong Jiemin Liao Chunyu Liu Yongmei Liu Cecilia M Lindgren Allan Linneberg Giovanni Malerba Vasiliki Mamakou Eirini Marouli Nisa M Maruthur Angela Matchan Roberta McKean-Cowdin Olga McLeod Ginger A Metcalf Karen L Mohlke Donna M Muzny Ioanna Ntalla Nicholette D Palmer Dorota Pasko Andreas Peter Nigel W Rayner Frida Renström Ken Rice Cinzia F Sala Bengt Sennblad Ioannis Serafetinidis Jennifer A Smith Nicole Soranzo Elizabeth K Speliotes Eli A Stahl Kathleen Stirrups Nikos Tentolouris Anastasia Thanopoulou Mina Torres Michela Traglia Emmanouil Tsafantakis Sundas Javad Lisa R Yanek Eleni Zengini Diane M Becker Joshua C Bis James B Brown L Adrienne Cupples Torben Hansen Erik Ingelsson Andrew J Karter Carlos Lorenzo Rasika A Mathias Jill M Norris Gina M Peloso Wayne H-H Sheu Daniela Toniolo Dhananjay Vaidya Rohit Varma Lynne E Wagenknecht Heiner Boeing Erwin P Bottinger George Dedoussis Panos Deloukas Ele Ferrannini Oscar H Franco Paul W Franks Richard A Gibbs Vilmundur Gudnason Anders Hamsten Tamara B Harris Andrew T Hattersley Caroline Hayward Albert Hofman Jan-Håkan Jansson Claudia Langenberg Lenore J Launer Daniel Levy Ben A Oostra Christopher J O'Donnell Stephen O'Rahilly Sandosh Padmanabhan James S Pankow Ozren Polasek Michael A Province Stephen S Rich Paul M Ridker Igor Rudan Matthias B Schulze Blair H Smith André G Uitterlinden Mark Walker Hugh Watkins Tien Y Wong Eleftheria Zeggini Markku Laakso Ingrid B Borecki Daniel I Chasman Oluf Pedersen Bruce M Psaty E Shyong Tai Cornelia M van Duijn Nicholas J Wareham Dawn M Waterworth Eric Boerwinkle W H Linda Kao Jose C Florez Ruth J F Loos James G Wilson Timothy M Frayling David S Siscovick Josée Dupuis Jerome I Rotter James B Meigs Robert A Scott Mark O Goodarzi

Nat Commun 2015 Jan 29;6:5897. Epub 2015 Jan 29.

1] Department of Medicine and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA [2] Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

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January 2015

A Bayesian method for analyzing lateral gene transfer.

Syst Biol 2014 May 20;63(3):409-20. Epub 2014 Feb 20.

Science for Life Laboratory, Tomtebodavägen 23A, 17165 Solna, Sweden, Department of Numerical Analysis and Computer Science, Stockholm University, Sweden, McGill Centre for Bioinformatics, 4th floor, Bellini Building, Life Sciences Complex, 3649 Promenade Sir William Osler, Montreal, Quebec, Canada, H3G 0B1, UMR CNRS 5558 - LBBE, "Biométrie et Biologie évolutive", UCB Lyon 1 - Bât. Grégor Mendel, 43 bd du 11 novembre 1918, 69622 VILLEURBANNE cedex, Department of Mechanics, Osquars Backe 18, KTH, SE-100 44 Stockholm, Sweden, Karolinska University Hospital, CMM L8:03, Solna, SE-171 76 Stockholm, Sweden and The School of Computer Science and Communication, Lindstedtsvägen 3, 5, KTH CSC, SE-100 44 Stockholm, Sweden.

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May 2014

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Authors:
Anubha Mahajan Min Jin Go Weihua Zhang Jennifer E Below Kyle J Gaulton Teresa Ferreira Momoko Horikoshi Andrew D Johnson Maggie C Y Ng Inga Prokopenko Danish Saleheen Xu Wang Eleftheria Zeggini Goncalo R Abecasis Linda S Adair Peter Almgren Mustafa Atalay Tin Aung Damiano Baldassarre Beverley Balkau Yuqian Bao Anthony H Barnett Ines Barroso Abdul Basit Latonya F Been John Beilby Graeme I Bell Rafn Benediktsson Richard N Bergman Bernhard O Boehm Eric Boerwinkle Lori L Bonnycastle Noël Burtt Qiuyin Cai Harry Campbell Jason Carey Stephane Cauchi Mark Caulfield Juliana C N Chan Li-Ching Chang Tien-Jyun Chang Yi-Cheng Chang Guillaume Charpentier Chien-Hsiun Chen Han Chen Yuan-Tsong Chen Kee-Seng Chia Manickam Chidambaram Peter S Chines Nam H Cho Young Min Cho Lee-Ming Chuang Francis S Collins Marylin C Cornelis David J Couper Andrew T Crenshaw Rob M van Dam John Danesh Debashish Das Ulf de Faire George Dedoussis Panos Deloukas Antigone S Dimas Christian Dina Alex S Doney Peter J Donnelly Mozhgan Dorkhan Cornelia van Duijn Josée Dupuis Sarah Edkins Paul Elliott Valur Emilsson Raimund Erbel Johan G Eriksson Jorge Escobedo Tonu Esko Elodie Eury Jose C Florez Pierre Fontanillas Nita G Forouhi Tom Forsen Caroline Fox Ross M Fraser Timothy M Frayling Philippe Froguel Philippe Frossard Yutang Gao Karl Gertow Christian Gieger Bruna Gigante Harald Grallert George B Grant Leif C Grrop Chrisropher J Groves Elin Grundberg Candace Guiducci Anders Hamsten Bok-Ghee Han Kazuo Hara Neelam Hassanali Andrew T Hattersley Caroline Hayward Asa K Hedman Christian Herder Albert Hofman Oddgeir L Holmen Kees Hovingh Astradur B Hreidarsson Cheng Hu Frank B Hu Jennie Hui Steve E Humphries Sarah E Hunt David J Hunter Kristian Hveem Zafar I Hydrie Hiroshi Ikegami Thomas Illig Erik Ingelsson Muhammed Islam Bo Isomaa Anne U Jackson Tazeen Jafar Alan James Weiping Jia Karl-Heinz Jöckel Anna Jonsson Jeremy B M Jowett Takashi Kadowaki Hyun Min Kang Stavroula Kanoni Wen Hong L Kao Sekar Kathiresan Norihiro Kato Prasad Katulanda Kirkka M Keinanen-Kiukaanniemi Ann M Kelly Hassan Khan Kay-Tee Khaw Chiea-Chuen Khor Hyung-Lae Kim Sangsoo Kim Young Jin Kim Leena Kinnunen Norman Klopp Augustine Kong Eeva Korpi-Hyövälti Sudhir Kowlessur Peter Kraft Jasmina Kravic Malene M Kristensen S Krithika Ashish Kumar Jesus Kumate Johanna Kuusisto Soo Heon Kwak Markku Laakso Vasiliki Lagou Timo A Lakka Claudia Langenberg Cordelia Langford Robert Lawrence Karin Leander Jen-Mai Lee Nanette R Lee Man Li Xinzhong Li Yun Li Junbin Liang Samuel Liju Wei-Yen Lim Lars Lind Cecilia M Lindgren Eero Lindholm Ching-Ti Liu Jian Jun Liu Stéphane Lobbens Jirong Long Ruth J F Loos Wei Lu Jian'an Luan Valeriya Lyssenko Ronald C W Ma Shiro Maeda Reedik Mägi Satu Männisto David R Matthews James B Meigs Olle Melander Andres Metspalu Julia Meyer Ghazala Mirza Evelin Mihailov Susanne Moebus Viswanathan Mohan Karen L Mohlke Andrew D Morris Thomas W Mühleisen Martina Müller-Nurasyid Bill Musk Jiro Nakamura Eitaro Nakashima Pau Navarro Peng-Keat Ng Alexandra C Nica Peter M Nilsson Inger Njølstad Markus M Nöthen Keizo Ohnaka Twee Hee Ong Katharine R Owen Colin N A Palmer James S Pankow Kyong Soo Park Melissa Parkin Sonali Pechlivanis Nancy L Pedersen Leena Peltonen John R B Perry Annette Peters Janini M Pinidiyapathirage Carl G Platou Simon Potter Jackie F Price Lu Qi Venkatesan Radha Loukianos Rallidis Asif Rasheed Wolfgang Rathman Rainer Rauramaa Soumya Raychaudhuri N William Rayner Simon D Rees Emil Rehnberg Samuli Ripatti Neil Robertson Michael Roden Elizabeth J Rossin Igor Rudan Denis Rybin Timo E Saaristo Veikko Salomaa Juha Saltevo Maria Samuel Dharambir K Sanghera Jouko Saramies James Scott Laura J Scott Robert A Scott Ayellet V Segrè Joban Sehmi Bengt Sennblad Nabi Shah Sonia Shah A Samad Shera Xiao Ou Shu Alan R Shuldiner Gunnar Sigurđsson Eric Sijbrands Angela Silveira Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Wing Yee So Alena Stančáková Kari Stefansson Gerald Steinbach Valgerdur Steinthorsdottir Kathleen Stirrups Rona J Strawbridge Heather M Stringham Qi Sun Chen Suo Ann-Christine Syvänen Ryoichi Takayanagi Fumihiko Takeuchi Wan Ting Tay Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Joseph Trakalo Elena Tremoli Mieke D Trip Fuu Jen Tsai Tiinamaija Tuomi Jaakko Tuomilehto Andre G Uitterlinden Adan Valladares-Salgado Sailaja Vedantam Fabrizio Veglia Benjamin F Voight Congrong Wang Nicholas J Wareham Roman Wennauer Ananda R Wickremasinghe Tom Wilsgaard James F Wilson Steven Wiltshire Wendy Winckler Tien Yin Wong Andrew R Wood Jer-Yuarn Wu Ying Wu Ken Yamamoto Toshimasa Yamauchi Mingyu Yang Loic Yengo Mitsuhiro Yokota Robin Young Delilah Zabaneh Fan Zhang Rong Zhang Wei Zheng Paul Z Zimmet David Altshuler Donald W Bowden Yoon Shin Cho Nancy J Cox Miguel Cruz Craig L Hanis Jaspal Kooner Jong-Young Lee Mark Seielstad Yik Ying Teo Michael Boehnke Esteban J Parra Jonh C Chambers E Shyong Tai Mark I McCarthy Andrew P Morris

Nat Genet 2014 Mar 9;46(3):234-44. Epub 2014 Feb 9.

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March 2014

Serum 25-hydroxyvitamin D concentration in subclinical carotid atherosclerosis.

Arterioscler Thromb Vasc Biol 2013 Nov 26;33(11):2633-8. Epub 2013 Sep 26.

From the Department of Molecular Medicine and Surgery (A.D., S.G, C.-G.Ö., J.Ö., A.H.), Atherosclerosis Research Unit, Department of Medicine Solna (A.D., O.P., A.S., K.G., B.S., R.J.S., M.L.), Division of Cardiovascular Epidemiology, Institute of Environmental Medicine (K.L., B.G., U.d.F.), Karolinska Institutet, Stockholm, Sweden; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano & Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.B., F.V., E.T.); Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland (J.K.); Foundation for Research in Health, Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland (R.R.); Department of Medicine, University Medical Center Groningen, Groningen, The Netherlands (A.J.S.); Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy (E.M.); Assistance Publique-Hopitaux de Paris, Service Endocrinologie-Metabolisme, Groupe Hôpitalier Pitie-Salpetriere, Unités de Prévention Cardiovasculaire, Paris, France (P.G.); and Centre for Cardiovascular Genetics, University College London, London, United Kingdom (S.E.H.).

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November 2013

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Authors:
Maria Sabater-Lleal Jie Huang Daniel Chasman Silvia Naitza Abbas Dehghan Andrew D Johnson Alexander Teumer Alex P Reiner Lasse Folkersen Saonli Basu Alicja R Rudnicka Stella Trompet Anders Mälarstig Jens Baumert Joshua C Bis Xiuqing Guo Jouke J Hottenga So-Youn Shin Lorna M Lopez Jari Lahti Toshiko Tanaka Lisa R Yanek Tiphaine Oudot-Mellakh James F Wilson Pau Navarro Jennifer E Huffman Tatijana Zemunik Susan Redline Reena Mehra Drazen Pulanic Igor Rudan Alan F Wright Ivana Kolcic Ozren Polasek Sarah H Wild Harry Campbell J David Curb Robert Wallace Simin Liu Charles B Eaton Diane M Becker Lewis C Becker Stefania Bandinelli Katri Räikkönen Elisabeth Widen Aarno Palotie Myriam Fornage David Green Myron Gross Gail Davies Sarah E Harris David C Liewald John M Starr Frances M K Williams Peter J Grant Timothy D Spector Rona J Strawbridge Angela Silveira Bengt Sennblad Fernando Rivadeneira Andre G Uitterlinden Oscar H Franco Albert Hofman Jenny van Dongen Gonneke Willemsen Dorret I Boomsma Jie Yao Nancy Swords Jenny Talin Haritunians Barbara McKnight Thomas Lumley Kent D Taylor Jerome I Rotter Bruce M Psaty Annette Peters Christian Gieger Thomas Illig Anne Grotevendt Georg Homuth Henry Völzke Thomas Kocher Anuj Goel Maria Grazia Franzosi Udo Seedorf Robert Clarke Maristella Steri Kirill V Tarasov Serena Sanna David Schlessinger David J Stott Naveed Sattar Brendan M Buckley Ann Rumley Gordon D Lowe Wendy L McArdle Ming-Huei Chen Geoffrey H Tofler Jaejoon Song Eric Boerwinkle Aaron R Folsom Lynda M Rose Anders Franco-Cereceda Martina Teichert M Arfan Ikram Thomas H Mosley Steve Bevan Martin Dichgans Peter M Rothwell Cathie L M Sudlow Jemma C Hopewell John C Chambers Danish Saleheen Jaspal S Kooner John Danesh Christopher P Nelson Jeanette Erdmann Muredach P Reilly Sekar Kathiresan Heribert Schunkert Pierre-Emmanuel Morange Luigi Ferrucci Johan G Eriksson David Jacobs Ian J Deary Nicole Soranzo Jacqueline C M Witteman Eco J C de Geus Russell P Tracy Caroline Hayward Wolfgang Koenig Francesco Cucca J Wouter Jukema Per Eriksson Sudha Seshadri Hugh S Markus Hugh Watkins Nilesh J Samani Henri Wallaschofski Nicholas L Smith David Tregouet Paul M Ridker Weihong Tang David P Strachan Anders Hamsten Christopher J O'Donnell

Circulation 2013 Sep 22;128(12):1310-24. Epub 2013 Aug 22.

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September 2013

GenPhyloData: realistic simulation of gene family evolution.

BMC Bioinformatics 2013 Jun 27;14:209. Epub 2013 Jun 27.

Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden.

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June 2013

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Blood 2012 Dec 18;120(24):4873-81. Epub 2012 Sep 18.

National Heart, Lung, and Blood Institute (NHBLI) Framingham Heart Study, Framingham, MA 01702, USA.

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December 2012

DLRS: gene tree evolution in light of a species tree.

Bioinformatics 2012 Nov 14;28(22):2994-5. Epub 2012 Sep 14.

Science for Life Laboratory, Stockholm University, SE-17121, Solna, Sweden.

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November 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

Authors:
Andrew P Morris Benjamin F Voight Tanya M Teslovich Teresa Ferreira Ayellet V Segrè Valgerdur Steinthorsdottir Rona J Strawbridge Hassan Khan Harald Grallert Anubha Mahajan Inga Prokopenko Hyun Min Kang Christian Dina Tonu Esko Ross M Fraser Stavroula Kanoni Ashish Kumar Vasiliki Lagou Claudia Langenberg Jian'an Luan Cecilia M Lindgren Martina Müller-Nurasyid Sonali Pechlivanis N William Rayner Laura J Scott Steven Wiltshire Loic Yengo Leena Kinnunen Elizabeth J Rossin Soumya Raychaudhuri Andrew D Johnson Antigone S Dimas Ruth J F Loos Sailaja Vedantam Han Chen Jose C Florez Caroline Fox Ching-Ti Liu Denis Rybin David J Couper Wen Hong L Kao Man Li Marilyn C Cornelis Peter Kraft Qi Sun Rob M van Dam Heather M Stringham Peter S Chines Krista Fischer Pierre Fontanillas Oddgeir L Holmen Sarah E Hunt Anne U Jackson Augustine Kong Robert Lawrence Julia Meyer John R B Perry Carl G P Platou Simon Potter Emil Rehnberg Neil Robertson Suthesh Sivapalaratnam Alena Stančáková Kathleen Stirrups Gudmar Thorleifsson Emmi Tikkanen Andrew R Wood Peter Almgren Mustafa Atalay Rafn Benediktsson Lori L Bonnycastle Noël Burtt Jason Carey Guillaume Charpentier Andrew T Crenshaw Alex S F Doney Mozhgan Dorkhan Sarah Edkins Valur Emilsson Elodie Eury Tom Forsen Karl Gertow Bruna Gigante George B Grant Christopher J Groves Candace Guiducci Christian Herder Astradur B Hreidarsson Jennie Hui Alan James Anna Jonsson Wolfgang Rathmann Norman Klopp Jasmina Kravic Kaarel Krjutškov Cordelia Langford Karin Leander Eero Lindholm Stéphane Lobbens Satu Männistö Ghazala Mirza Thomas W Mühleisen Bill Musk Melissa Parkin Loukianos Rallidis Jouko Saramies Bengt Sennblad Sonia Shah Gunnar Sigurðsson Angela Silveira Gerald Steinbach Barbara Thorand Joseph Trakalo Fabrizio Veglia Roman Wennauer Wendy Winckler Delilah Zabaneh Harry Campbell Cornelia van Duijn Andre G Uitterlinden Albert Hofman Eric Sijbrands Goncalo R Abecasis Katharine R Owen Eleftheria Zeggini Mieke D Trip Nita G Forouhi Ann-Christine Syvänen Johan G Eriksson Leena Peltonen Markus M Nöthen Beverley Balkau Colin N A Palmer Valeriya Lyssenko Tiinamaija Tuomi Bo Isomaa David J Hunter Lu Qi Alan R Shuldiner Michael Roden Ines Barroso Tom Wilsgaard John Beilby Kees Hovingh Jackie F Price James F Wilson Rainer Rauramaa Timo A Lakka Lars Lind George Dedoussis Inger Njølstad Nancy L Pedersen Kay-Tee Khaw Nicholas J Wareham Sirkka M Keinanen-Kiukaanniemi Timo E Saaristo Eeva Korpi-Hyövälti Juha Saltevo Markku Laakso Johanna Kuusisto Andres Metspalu Francis S Collins Karen L Mohlke Richard N Bergman Jaakko Tuomilehto Bernhard O Boehm Christian Gieger Kristian Hveem Stephane Cauchi Philippe Froguel Damiano Baldassarre Elena Tremoli Steve E Humphries Danish Saleheen John Danesh Erik Ingelsson Samuli Ripatti Veikko Salomaa Raimund Erbel Karl-Heinz Jöckel Susanne Moebus Annette Peters Thomas Illig Ulf de Faire Anders Hamsten Andrew D Morris Peter J Donnelly Timothy M Frayling Andrew T Hattersley Eric Boerwinkle Olle Melander Sekar Kathiresan Peter M Nilsson Panos Deloukas Unnur Thorsteinsdottir Leif C Groop Kari Stefansson Frank Hu James S Pankow Josée Dupuis James B Meigs David Altshuler Michael Boehnke Mark I McCarthy

Nat Genet 2012 Sep 12;44(9):981-90. Epub 2012 Aug 12.

Wellcome Trust Centre for Human Genetics, University of Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442244PMC
September 2012

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

Authors:
Robert A Scott Vasiliki Lagou Ryan P Welch Eleanor Wheeler May E Montasser Jian'an Luan Reedik Mägi Rona J Strawbridge Emil Rehnberg Stefan Gustafsson Stavroula Kanoni Laura J Rasmussen-Torvik Loïc Yengo Cecile Lecoeur Dmitry Shungin Serena Sanna Carlo Sidore Paul C D Johnson J Wouter Jukema Toby Johnson Anubha Mahajan Niek Verweij Gudmar Thorleifsson Jouke-Jan Hottenga Sonia Shah Albert V Smith Bengt Sennblad Christian Gieger Perttu Salo Markus Perola Nicholas J Timpson David M Evans Beate St Pourcain Ying Wu Jeanette S Andrews Jennie Hui Lawrence F Bielak Wei Zhao Momoko Horikoshi Pau Navarro Aaron Isaacs Jeffrey R O'Connell Kathleen Stirrups Veronique Vitart Caroline Hayward Tõnu Esko Evelin Mihailov Ross M Fraser Tove Fall Benjamin F Voight Soumya Raychaudhuri Han Chen Cecilia M Lindgren Andrew P Morris Nigel W Rayner Neil Robertson Denis Rybin Ching-Ti Liu Jacques S Beckmann Sara M Willems Peter S Chines Anne U Jackson Hyun Min Kang Heather M Stringham Kijoung Song Toshiko Tanaka John F Peden Anuj Goel Andrew A Hicks Ping An Martina Müller-Nurasyid Anders Franco-Cereceda Lasse Folkersen Letizia Marullo Hanneke Jansen Albertine J Oldehinkel Marcel Bruinenberg James S Pankow Kari E North Nita G Forouhi Ruth J F Loos Sarah Edkins Tibor V Varga Göran Hallmans Heikki Oksa Mulas Antonella Ramaiah Nagaraja Stella Trompet Ian Ford Stephan J L Bakker Augustine Kong Meena Kumari Bruna Gigante Christian Herder Patricia B Munroe Mark Caulfield Jula Antti Massimo Mangino Kerrin Small Iva Miljkovic Yongmei Liu Mustafa Atalay Wieland Kiess Alan L James Fernando Rivadeneira Andre G Uitterlinden Colin N A Palmer Alex S F Doney Gonneke Willemsen Johannes H Smit Susan Campbell Ozren Polasek Lori L Bonnycastle Serge Hercberg Maria Dimitriou Jennifer L Bolton Gerard R Fowkes Peter Kovacs Jaana Lindström Tatijana Zemunik Stefania Bandinelli Sarah H Wild Hanneke V Basart Wolfgang Rathmann Harald Grallert Winfried Maerz Marcus E Kleber Bernhard O Boehm Annette Peters Peter P Pramstaller Michael A Province Ingrid B Borecki Nicholas D Hastie Igor Rudan Harry Campbell Hugh Watkins Martin Farrall Michael Stumvoll Luigi Ferrucci Dawn M Waterworth Richard N Bergman Francis S Collins Jaakko Tuomilehto Richard M Watanabe Eco J C de Geus Brenda W Penninx Albert Hofman Ben A Oostra Bruce M Psaty Peter Vollenweider James F Wilson Alan F Wright G Kees Hovingh Andres Metspalu Matti Uusitupa Patrik K E Magnusson Kirsten O Kyvik Jaakko Kaprio Jackie F Price George V Dedoussis Panos Deloukas Pierre Meneton Lars Lind Michael Boehnke Alan R Shuldiner Cornelia M van Duijn Andrew D Morris Anke Toenjes Patricia A Peyser John P Beilby Antje Körner Johanna Kuusisto Markku Laakso Stefan R Bornstein Peter E H Schwarz Timo A Lakka Rainer Rauramaa Linda S Adair George Davey Smith Tim D Spector Thomas Illig Ulf de Faire Anders Hamsten Vilmundur Gudnason Mika Kivimaki Aroon Hingorani Sirkka M Keinanen-Kiukaanniemi Timo E Saaristo Dorret I Boomsma Kari Stefansson Pim van der Harst Josée Dupuis Nancy L Pedersen Naveed Sattar Tamara B Harris Francesco Cucca Samuli Ripatti Veikko Salomaa Karen L Mohlke Beverley Balkau Philippe Froguel Anneli Pouta Marjo-Riitta Jarvelin Nicholas J Wareham Nabila Bouatia-Naji Mark I McCarthy Paul W Franks James B Meigs Tanya M Teslovich Jose C Florez Claudia Langenberg Erik Ingelsson Inga Prokopenko Inês Barroso

Nat Genet 2012 Sep 12;44(9):991-1005. Epub 2012 Aug 12.

Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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September 2012

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

Authors:
Alisa K Manning Marie-France Hivert Robert A Scott Jonna L Grimsby Nabila Bouatia-Naji Han Chen Denis Rybin Ching-Ti Liu Lawrence F Bielak Inga Prokopenko Najaf Amin Daniel Barnes Gemma Cadby Jouke-Jan Hottenga Erik Ingelsson Anne U Jackson Toby Johnson Stavroula Kanoni Claes Ladenvall Vasiliki Lagou Jari Lahti Cecile Lecoeur Yongmei Liu Maria Teresa Martinez-Larrad May E Montasser Pau Navarro John R B Perry Laura J Rasmussen-Torvik Perttu Salo Naveed Sattar Dmitry Shungin Rona J Strawbridge Toshiko Tanaka Cornelia M van Duijn Ping An Mariza de Andrade Jeanette S Andrews Thor Aspelund Mustafa Atalay Yurii Aulchenko Beverley Balkau Stefania Bandinelli Jacques S Beckmann John P Beilby Claire Bellis Richard N Bergman John Blangero Mladen Boban Michael Boehnke Eric Boerwinkle Lori L Bonnycastle Dorret I Boomsma Ingrid B Borecki Yvonne Böttcher Claude Bouchard Eric Brunner Danijela Budimir Harry Campbell Olga Carlson Peter S Chines Robert Clarke Francis S Collins Arturo Corbatón-Anchuelo David Couper Ulf de Faire George V Dedoussis Panos Deloukas Maria Dimitriou Josephine M Egan Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Elodie Eury Luigi Ferrucci Ian Ford Nita G Forouhi Caroline S Fox Maria Grazia Franzosi Paul W Franks Timothy M Frayling Philippe Froguel Pilar Galan Eco de Geus Bruna Gigante Nicole L Glazer Anuj Goel Leif Groop Vilmundur Gudnason Göran Hallmans Anders Hamsten Ola Hansson Tamara B Harris Caroline Hayward Simon Heath Serge Hercberg Andrew A Hicks Aroon Hingorani Albert Hofman Jennie Hui Joseph Hung Marjo-Riitta Jarvelin Min A Jhun Paul C D Johnson J Wouter Jukema Antti Jula W H Kao Jaakko Kaprio Sharon L R Kardia Sirkka Keinanen-Kiukaanniemi Mika Kivimaki Ivana Kolcic Peter Kovacs Meena Kumari Johanna Kuusisto Kirsten Ohm Kyvik Markku Laakso Timo Lakka Lars Lannfelt G Mark Lathrop Lenore J Launer Karin Leander Guo Li Lars Lind Jaana Lindstrom Stéphane Lobbens Ruth J F Loos Jian'an Luan Valeriya Lyssenko Reedik Mägi Patrik K E Magnusson Michael Marmot Pierre Meneton Karen L Mohlke Vincent Mooser Mario A Morken Iva Miljkovic Narisu Narisu Jeff O'Connell Ken K Ong Ben A Oostra Lyle J Palmer Aarno Palotie James S Pankow John F Peden Nancy L Pedersen Marina Pehlic Leena Peltonen Brenda Penninx Marijana Pericic Markus Perola Louis Perusse Patricia A Peyser Ozren Polasek Peter P Pramstaller Michael A Province Katri Räikkönen Rainer Rauramaa Emil Rehnberg Ken Rice Jerome I Rotter Igor Rudan Aimo Ruokonen Timo Saaristo Maria Sabater-Lleal Veikko Salomaa David B Savage Richa Saxena Peter Schwarz Udo Seedorf Bengt Sennblad Manuel Serrano-Rios Alan R Shuldiner Eric J G Sijbrands David S Siscovick Johannes H Smit Kerrin S Small Nicholas L Smith Albert Vernon Smith Alena Stančáková Kathleen Stirrups Michael Stumvoll Yan V Sun Amy J Swift Anke Tönjes Jaakko Tuomilehto Stella Trompet Andre G Uitterlinden Matti Uusitupa Max Vikström Veronique Vitart Marie-Claude Vohl Benjamin F Voight Peter Vollenweider Gerard Waeber Dawn M Waterworth Hugh Watkins Eleanor Wheeler Elisabeth Widen Sarah H Wild Sara M Willems Gonneke Willemsen James F Wilson Jacqueline C M Witteman Alan F Wright Hanieh Yaghootkar Diana Zelenika Tatijana Zemunik Lina Zgaga Nicholas J Wareham Mark I McCarthy Ines Barroso Richard M Watanabe Jose C Florez Josée Dupuis James B Meigs Claudia Langenberg

Nat Genet 2012 May 13;44(6):659-69. Epub 2012 May 13.

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.

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May 2012

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Authors:
Daniel I Swerdlow Michael V Holmes Karoline B Kuchenbaecker Jorgen E L Engmann Tina Shah Reecha Sofat Yiran Guo Christina Chung Anne Peasey Roman Pfister Simon P Mooijaart Helen A Ireland Maarten Leusink Claudia Langenberg Ka Wah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos John Hardy Michael A Nalls Yun Rose Li Gordon Lowe Marlene Stewart Suzette J Bielinski Julian Peto Nicholas J Timpson John Gallacher Malcolm Dunlop Richard Houlston Ian Tomlinson Ioanna Tzoulaki Jian'an Luan Jolanda M A Boer Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Luigi Ferrucci Stefania Bandenelli Toshiko Tanaka James F Meschia Andrew Singleton Gerjan Navis Irene Mateo Leach Stephan J L Bakker Ron T Gansevoort Ian Ford Stephen E Epstein Mary Susan Burnett Joe M Devaney J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Yolanda van der Graaf Pim A de Jong Anke-Hilse Mailand-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Jeffrey W Stephens Charles B Eaton Jennifer G Robinson JoAnn E Manson F Gerry Fowkes Timonthy M Frayling Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Susan Redline Leslie A Lange Meena Kumari Nick J Wareham W M Monique Verschuren Emelia J Benjamin John C Whittaker Anders Hamsten Frank Dudbridge J A Chris Delaney Andrew Wong Diana Kuh Rebecca Hardy Berta Almoguera Castillo John J Connolly Pim van der Harst Eric J Brunner Michael G Marmot Christina L Wassel Steve E Humphries Philippa J Talmud Mika Kivimaki Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Hakon Hakonarson Alex P Reiner Brendan J Keating Naveed Sattar Aroon D Hingorani Juan Pablo Casas

Lancet 2012 Mar 14;379(9822):1214-24. Epub 2012 Mar 14.

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March 2012

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Authors:
Rona J Strawbridge Josée Dupuis Inga Prokopenko Adam Barker Emma Ahlqvist Denis Rybin John R Petrie Mary E Travers Nabila Bouatia-Naji Antigone S Dimas Alexandra Nica Eleanor Wheeler Han Chen Benjamin F Voight Jalal Taneera Stavroula Kanoni John F Peden Fabiola Turrini Stefan Gustafsson Carina Zabena Peter Almgren David J P Barker Daniel Barnes Elaine M Dennison Johan G Eriksson Per Eriksson Elodie Eury Lasse Folkersen Caroline S Fox Timothy M Frayling Anuj Goel Harvest F Gu Momoko Horikoshi Bo Isomaa Anne U Jackson Karen A Jameson Eero Kajantie Julie Kerr-Conte Teemu Kuulasmaa Johanna Kuusisto Ruth J F Loos Jian'an Luan Konstantinos Makrilakis Alisa K Manning María Teresa Martínez-Larrad Narisu Narisu Maria Nastase Mannila John Ohrvik Clive Osmond Laura Pascoe Felicity Payne Avan A Sayer Bengt Sennblad Angela Silveira Alena Stancáková Kathy Stirrups Amy J Swift Ann-Christine Syvänen Tiinamaija Tuomi Ferdinand M van 't Hooft Mark Walker Michael N Weedon Weijia Xie Björn Zethelius Halit Ongen Anders Mälarstig Jemma C Hopewell Danish Saleheen John Chambers Sarah Parish John Danesh Jaspal Kooner Claes-Göran Ostenson Lars Lind Cyrus C Cooper Manuel Serrano-Ríos Ele Ferrannini Tom J Forsen Robert Clarke Maria Grazia Franzosi Udo Seedorf Hugh Watkins Philippe Froguel Paul Johnson Panos Deloukas Francis S Collins Markku Laakso Emmanouil T Dermitzakis Michael Boehnke Mark I McCarthy Nicholas J Wareham Leif Groop François Pattou Anna L Gloyn George V Dedoussis Valeriya Lyssenko James B Meigs Inês Barroso Richard M Watanabe Erik Ingelsson Claudia Langenberg Anders Hamsten Jose C Florez

Diabetes 2011 Oct 26;60(10):2624-34. Epub 2011 Aug 26.

Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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October 2011

Evaluation of Bayesian models of substitution rate evolution--parental guidance versus mutual independence.

Syst Biol 2011 May 8;60(3):329-42. Epub 2011 Mar 8.

Department of Mathematics, Uppsala University, Box 480, SE-751 06 Uppsala, Sweden.

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May 2011

Probabilistic orthology analysis.

Syst Biol 2009 Aug 18;58(4):411-24. Epub 2009 Aug 18.

Stockholm Bioinformatics Center, Department of Biochemistry, Stockholm University, AlbaNova, 106 91 Stockholm, Sweden.

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August 2009

Simultaneous Bayesian gene tree reconstruction and reconciliation analysis.

Proc Natl Acad Sci U S A 2009 Apr 19;106(14):5714-9. Epub 2009 Mar 19.

School for Computer Science and Communication, Royal Institute of Technology, SE-10044 Stockholm, Sweden.

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April 2009

Birth-death prior on phylogeny and speed dating.

BMC Evol Biol 2008 Mar 4;8:77. Epub 2008 Mar 4.

Stockholm Bioinformatics Centre, Albanova, Stockholm University, SE-10691 Stockholm, Sweden.

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March 2008

primetv: a viewer for reconciled trees.

BMC Bioinformatics 2007 May 7;8:148. Epub 2007 May 7.

Stockholm Bioinformatics Center and Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.

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May 2007

Complex HTR2C linkage disequilibrium and promoter associations with body mass index and serum leptin.

Hum Genet 2005 Oct 14;117(6):545-57. Epub 2005 Jul 14.

Center for Genomics and Bioinformatics, Karolinska Institutet, Berzelius Väg 35, 17177 Stockholm, Sweden.

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October 2005

Bayesian gene/species tree reconciliation and orthology analysis using MCMC.

Bioinformatics 2003 ;19 Suppl 1:i7-15

SBC and Center for Genomics and Bioinforamtics, Karolinska Instituet, SE-171 77, Stockholm, Sweden.

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October 2004

Classification of apocynaceae s.l. according to a new approach combining Linnaean and phylogenetic taxonomy.

Syst Biol 2002 Jun;51(3):389-409

Department of Systematic Botany, Evolutionary Biology Center (EBC), Uppsala University, Norbyv. 18D, SE-752 36 Uppsala, Sweden.

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June 2002