Publications by authors named "Benedicte Jordan"

98Publications

Acetate: Friend or foe against breast tumour growth in the context of obesity?

J Cell Mol Med 2020 Oct 26. Epub 2020 Oct 26.

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute, UCLouvain, Brussels, Belgium.

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http://dx.doi.org/10.1111/jcmm.16034DOI Listing
October 2020

Obesity and triple-negative-breast-cancer: Is apelin a new key target?

J Cell Mol Med 2020 Jul 17. Epub 2020 Jul 17.

Metabolism & Nutrition Research Group, Louvain Drug Research Institute, WELBIO (Walloon Excellence in Life sciences and BIOtechnology), UCLouvain, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1111/jcmm.15639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520321PMC
July 2020

Metabolic imaging using hyperpolarized C-pyruvate to assess sensitivity to the B-Raf inhibitor vemurafenib in melanoma cells and xenografts.

J Cell Mol Med 2020 01 13;24(2):1934-1944. Epub 2019 Dec 13.

Biomedical Magnetic Resonance (REMA) Group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain (UCLouvain), Brussels, Belgium.

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http://dx.doi.org/10.1111/jcmm.14890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991684PMC
January 2020

Combined endogenous MR biomarkers to assess changes in tumor oxygenation induced by an allosteric effector of hemoglobin.

NMR Biomed 2020 02 25;33(2):e4181. Epub 2019 Nov 25.

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/nbm.4181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003919PMC
February 2020

Impact of myo-inositol trispyrophosphate (ITPP) on tumour oxygenation and response to irradiation in rodent tumour models.

J Cell Mol Med 2019 03 21;23(3):1908-1916. Epub 2018 Dec 21.

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.

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http://doi.wiley.com/10.1111/jcmm.14092
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http://dx.doi.org/10.1111/jcmm.14092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378184PMC
March 2019

Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer.

Nat Rev Gastroenterol Hepatol 2018 11;15(11):671-682

Université catholique de Louvain, Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Brussels, Belgium.

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http://dx.doi.org/10.1038/s41575-018-0025-6DOI Listing
November 2018

Imaging markers of response to combined BRAF and MEK inhibition in BRAF mutated vemurafenib-sensitive and resistant melanomas.

Oncotarget 2018 Mar 30;9(24):16832-16846. Epub 2018 Mar 30.

Université Catholique de Louvain, Louvain Drug Research Institute, Biomedical Magnetic Resonance Group, Brussels, Belgium.

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http://dx.doi.org/10.18632/oncotarget.24709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908289PMC
March 2018

Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects.

Nat Commun 2018 03 23;9(1):1208. Epub 2018 Mar 23.

Pole of Pharmacology and Therapeutics (FATH), Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, 53 Avenue Mounier B1.53.09, Brussels, B-1200, Belgium.

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http://dx.doi.org/10.1038/s41467-018-03525-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865202PMC
March 2018

Biomarkers of tumour redox status in response to modulations of glutathione and thioredoxin antioxidant pathways.

Free Radic Res 2018 Feb 31;52(2):256-266. Epub 2018 Jan 31.

a Louvain Drug Research Institute, Biomedical Magnetic Resonance Group, Université Catholique de Louvain (UCL) , Brussels , Belgium.

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http://dx.doi.org/10.1080/10715762.2018.1427236DOI Listing
February 2018

Adipose Tissue Metabolism and Cancer Progression: Novel Insights from Gut Microbiota?

Curr Pathobiol Rep 2017 24;5(4):315-322. Epub 2017 Oct 24.

Louvain Drug Research Institute, WELBIO (Walloon Excellence in Life Sciences and BIOtechnology), Metabolism and Nutrition Research group, Université Catholique de Louvain, Av. E. Mounier, 73 box B1.73.11, 1200 Brussels, Belgium.

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http://dx.doi.org/10.1007/s40139-017-0154-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684272PMC
October 2017

Combined endogenous MR biomarkers to predict basal tumor oxygenation and response to hyperoxic challenge.

NMR Biomed 2017 Dec 11;30(12). Epub 2017 Oct 11.

Université catholique de Louvain, Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Brussels, Belgium.

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http://dx.doi.org/10.1002/nbm.3836DOI Listing
December 2017

Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies.

Oncotarget 2017 Jun;8(24):38876-38885

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université Catholique de Louvain (UCL), Brussels, Belgium.

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http://dx.doi.org/10.18632/oncotarget.17103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503579PMC
June 2017

O MRS assesses the effect of mild hypothermia on oxygen consumption rate in tumors.

NMR Biomed 2017 Aug 21;30(8). Epub 2017 Apr 21.

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain (UCL), Belgium.

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http://doi.wiley.com/10.1002/nbm.3726
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http://dx.doi.org/10.1002/nbm.3726DOI Listing
August 2017

Assessing Tumor Oxygenation for Predicting Outcome in Radiation Oncology: A Review of Studies Correlating Tumor Hypoxic Status and Outcome in the Preclinical and Clinical Settings.

Front Oncol 2017 25;7:10. Epub 2017 Jan 25.

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique de Louvain , Brussels , Belgium.

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http://dx.doi.org/10.3389/fonc.2017.00010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263142PMC
January 2017

Manipulation of tumor oxygenation and radiosensitivity through modification of cell respiration. A critical review of approaches and imaging biomarkers for therapeutic guidance.

Biochim Biophys Acta Bioenerg 2017 Aug 12;1858(8):700-711. Epub 2017 Jan 12.

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Avenue Mounier 73.08, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.bbabio.2017.01.002DOI Listing
August 2017

Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo.

Neoplasia 2016 Dec 24;18(12):742-752. Epub 2016 Nov 24.

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2016.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126136PMC
December 2016

Monitoring Tumor Response to Carbogen Breathing by Oxygen-Sensitive Magnetic Resonance Parameters to Predict the Outcome of Radiation Therapy: A Preclinical Study.

Int J Radiat Oncol Biol Phys 2016 09 7;96(1):149-60. Epub 2016 May 7.

Université Catholique de Louvain, Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2016.04.029DOI Listing
September 2016

DW-MRI and (18) F-FLT PET for early assessment of response to radiation therapy associated with hypoxia-driven interventions. Preclinical studies using manipulation of oxygenation and/or dose escalation.

Contrast Media Mol Imaging 2016 Mar-Apr;11(2):115-21. Epub 2015 Oct 7.

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/cmmi.1670DOI Listing
December 2016

Direct Evidence of the Link Between Energetic Metabolism and Proliferation Capacity of Cancer Cells In Vitro.

Adv Exp Med Biol 2016 ;876:209-214

Biomedical Magnetic Resonance Research Group, Université catholique de Louvain (UCL), Avenue Mounier 73 (B1.73.08), 1200, Brussels, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-3023-4_26DOI Listing
May 2016

A Fast Hydrogen Sulfide-Releasing Donor Increases the Tumor Response to Radiotherapy.

Mol Cancer Ther 2016 Jan 18;15(1):154-61. Epub 2015 Dec 18.

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0691-TDOI Listing
January 2016

Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.

Int J Cancer 2016 Apr 9;138(8):2043-9. Epub 2015 Dec 9.

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique De Louvain (UCL), Avenue Mounier, 73 Box B1.73.08, Brussels, Belgium.

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http://dx.doi.org/10.1002/ijc.29932DOI Listing
April 2016

Mapping of global R1 and R2* values versus lipids R1 values as potential markers of hypoxia in human glial tumors: A feasibility study.

Magn Reson Imaging 2016 Feb 30;34(2):105-13. Epub 2015 Oct 30.

Department of Radiology, Cliniques Universitaires UCL-Saint-Luc, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mri.2015.10.021DOI Listing
February 2016

The increase in tumor oxygenation under carbogen breathing induces a decrease in the uptake of [(18)F]-fluoro-deoxy-glucose.

Radiother Oncol 2015 Sep 14;116(3):400-3. Epub 2015 May 14.

Biomedical Magnetic Resonance Research Group, Université catholique de Louvain (UCL), Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2015.04.023DOI Listing
September 2015

Tetrahydro Iso-Alpha Acids and Hexahydro Iso-Alpha Acids from Hops Inhibit Proliferation of Human Hepatocarcinoma Cell Lines and Reduce Diethylnitrosamine Induced Liver Tumor Formation in Rats.

Nutr Cancer 2015 5;67(5):748-60. Epub 2015 May 5.

a Institut de Recherche Expérimentale et Clinique, Pôle Hépato-gastroentérologie, Université catholique de Louvain , Brussels , Belgium and Department of Gastroenterology, Cliniques Universitaires St. Luc , Brussels , Belgium.

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http://dx.doi.org/10.1080/01635581.2015.1032429DOI Listing
May 2016

Monitoring Combretastatin A4-induced tumor hypoxia and hemodynamic changes using endogenous MR contrast and DCE-MRI.

Magn Reson Med 2016 Feb 12;75(2):866-72. Epub 2015 Mar 12.

Université Catholique de Louvain, Louvain Drug Research Institute, Biomedical Magnetic Resonance Group, Avenue Mounier 73, B1.73.08, Brussels, Belgium.

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http://dx.doi.org/10.1002/mrm.25642DOI Listing
February 2016

Induction of post-menstrual regeneration by ovarian steroid withdrawal in the functionalis of xenografted human endometrium.

Hum Reprod 2015 May 6;30(5):1156-68. Epub 2015 Mar 6.

Cell Biology Unit, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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http://dx.doi.org/10.1093/humrep/dev043DOI Listing
May 2015

Predictive value of (18)F-FAZA PET imaging for guiding the association of radiotherapy with nimorazole: a preclinical study.

Radiother Oncol 2015 Feb 20;114(2):189-94. Epub 2015 Jan 20.

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2014.12.015DOI Listing
February 2015

In vivo visualization and ex vivo quantification of murine breast cancer cells in the mouse brain using MRI cell tracking and electron paramagnetic resonance.

NMR Biomed 2015 Mar 22;28(3):367-75. Epub 2015 Jan 22.

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/nbm.3259DOI Listing
March 2015

Potential role of hypoxia imaging using (18)F-FAZA PET to guide hypoxia-driven interventions (carbogen breathing or dose escalation) in radiation therapy.

Radiother Oncol 2014 Nov 27;113(2):204-9. Epub 2014 Nov 27.

Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2014.09.016DOI Listing
November 2014

Qualification of a noninvasive magnetic resonance imaging biomarker to assess tumor oxygenation.

Clin Cancer Res 2014 Nov 10;20(21):5403-11. Epub 2014 Sep 10.

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3434DOI Listing
November 2014

Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence.

Contrast Media Mol Imaging 2014 Mar-Apr;9(2):143-53

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/cmmi.1553DOI Listing
October 2014

Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI.

Cancer Res 2014 Feb 27;74(3):686-94. Epub 2013 Nov 27.

Authors' Affiliations: Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium; and Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461058PMC
February 2014

Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.

Cancer Res 2014 Jan 12;74(1):24-30. Epub 2013 Nov 12.

Authors' Affiliations: Laboratory of Myeloid Cell Immunology, VIB; Laboratory of Cellular and Molecular Immunology; Cell Differentiation Unit, Diabetes Research Centre, Vrije Universiteit Brussel; Biomedical Magnetic Resonance Unit, U.C. Louvain, Brussels; Laboratory of Molecular Oncology and Angiogenesis; Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB; and Experimental Medicine and Endocrinology, Department of Experimental Medicine, K.U. Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1196DOI Listing
January 2014

Optimization of tumor radiotherapy with modulators of cell metabolism: toward clinical applications.

Semin Radiat Oncol 2013 Oct;23(4):262-72

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain (UCL) Medical School, Brussels, Belgium; Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL) Medical School, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.semradonc.2013.05.008DOI Listing
October 2013

Application of MOBILE (mapping of oxygen by imaging lipids relaxation enhancement) to study variations in tumor oxygenation.

Adv Exp Med Biol 2013 ;789:281-288

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute, Université Catholique de Louvain, Av.Mounier 73.40, Brussels, 1200, Belgium.

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http://dx.doi.org/10.1007/978-1-4614-7411-1_38DOI Listing
May 2014

Tumor reoxygenation following administration of the EGFR inhibitor, gefitinib, in experimental tumors.

Adv Exp Med Biol 2013 ;789:265-271

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université catholique de Louvain, Av.Mounier 73.40, 1200, Brussels, Belgium.

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http://dx.doi.org/10.1007/978-1-4614-7411-1_36DOI Listing
May 2014

Hypoxia is not required for human endometrial breakdown or repair in a xenograft model of menstruation.

FASEB J 2013 Sep 31;27(9):3711-9. Epub 2013 May 31.

Cell Biology Unit, de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1096/fj.13-232074DOI Listing
September 2013

Potentiation of radiotherapy by a localized antiangiogenic gene therapy.

Radiother Oncol 2013 May 23;107(2):252-8. Epub 2013 Apr 23.

Université Catholique de Louvain, Louvain Drug Research Institute, Pharmaceutics and Drug Delivery, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2013.03.018DOI Listing
May 2013

Multimodal imaging of tumor response to sorafenib combined with radiation therapy: comparison between diffusion-weighted MRI, choline spectroscopy and 18F-FLT PET imaging.

Contrast Media Mol Imaging 2013 May-Jun;8(3):274-80

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique de Louvain, Belgium, Avenue Mounier 73, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1002/cmmi.1525DOI Listing
November 2013

Improvement of subcutaneous bioartificial pancreas vascularization and function by coencapsulation of pig islets and mesenchymal stem cells in primates.

Cell Transplant 2014 4;23(11):1349-64. Epub 2013 Feb 4.

Université Catholique de Louvain, Secteur des Sciences de la Santé, Institute of Clinical and Experimental Research, Pôle de Chirurgie Expérimentale et Transplantation, Brussels, Belgium.

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http://dx.doi.org/10.3727/096368913X663550DOI Listing
June 2015

Influence of cell detachment on the respiration rate of tumor and endothelial cells.

PLoS One 2013 30;8(1):e53324. Epub 2013 Jan 30.

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain (UCL), Brussels, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053324PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559693PMC
September 2013

Hypoxia imaging with the nitroimidazole 18F-FAZA PET tracer: a comparison with OxyLite, EPR oximetry and 19F-MRI relaxometry.

Radiother Oncol 2012 Oct 6;105(1):29-35. Epub 2012 Jun 6.

Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2012.04.011DOI Listing
October 2012

Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy.

Front Pharmacol 2012 21;3:94. Epub 2012 May 21.

Nuclear Magnetic Resonance Research Group, Louvain Drug Research Institute, Université catholique de Louvain Medical School Brussels, Belgium.

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http://dx.doi.org/10.3389/fphar.2012.00094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357106PMC
October 2012

Hexafluorobenzene in comparison with perfluoro-15-crown-5-ether for repeated monitoring of oxygenation using 19F MRI in a mouse model.

Magn Reson Med 2013 Jan 22;69(1):248-54. Epub 2012 Mar 22.

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/mrm.24245DOI Listing
January 2013

Arsenic trioxide treatment decreases the oxygen consumption rate of tumor cells and radiosensitizes solid tumors.

Cancer Res 2012 Jan 2;72(2):482-90. Epub 2011 Dec 2.

Biomedical Magnetic Resonance Group, Louvain Research Institute, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1755DOI Listing
January 2012

In vivo mapping of tumor oxygen consumption using (19)F MRI relaxometry.

NMR Biomed 2011 Jun 3;24(5):458-63. Epub 2010 Oct 3.

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/nbm.1604DOI Listing
June 2011

Surrogate MR markers of response to chemo- or radiotherapy in association with co-treatments: a retrospective analysis of multi-modal studies.

Contrast Media Mol Imaging 2010 Nov-Dec;5(6):323-32

Laboratory of Biomedical Magnetic Resonance, Louvain Drug Research Institute, Université Catholique de Louvain, Avenue Mounier 73, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1002/cmmi.397DOI Listing
March 2011

Captopril and S-nitrosocaptopril as potent radiosensitizers: Comparative study and underlying mechanisms.

Cancer Lett 2010 Jul 9;293(2):213-9. Epub 2010 Feb 9.

Biomedical Magnetic Resonance Unit, Louvain Drug Research Institute, Université Catholique de Louvain, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.canlet.2010.01.016DOI Listing
July 2010

In vivo selection of biocompatible alginates for islet encapsulation and subcutaneous transplantation.

Tissue Eng Part A 2010 May;16(5):1503-13

Laboratory of Experimental Surgery, Université Catholique de Louvain, Faculté de Médecine, Brussels, Belgium.

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http://dx.doi.org/10.1089/ten.TEA.2009.0286DOI Listing
May 2010

Decrease in tumor cell oxygen consumption after treatment with vandetanib (ZACTIMA; ZD6474) and its effect on response to radiotherapy.

Radiat Res 2009 Nov;172(5):584-91

Biomedical Magnetic Resonance Unit, Louvain Drug Research Institute, Université Catholique de Louvain, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1667/RR1744.1DOI Listing
November 2009

Comparison of methods for measuring oxygen consumption in tumor cells in vitro.

Anal Biochem 2010 Jan 18;396(2):250-6. Epub 2009 Sep 18.

Laboratory of Biomedical Magnetic Resonance, Louvain Drug Research Institute, Université catholique de Louvain, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.ab.2009.09.029DOI Listing
January 2010

A New EPR oximetry protocol to estimate the tissue oxygen consumption in vivo.

Radiat Res 2009 Aug;172(2):220-5

Laboratory of Biomedical Magnetic Resonance, Université catholique de Louvain, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1667/RR1448.1DOI Listing
August 2009

Use of Xanthinol Nicotinate as a co-treatment for radio- and chemo-therapy in experimental tumors.

Int J Cancer 2010 Jan;126(2):583-8

Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/ijc.24724DOI Listing
January 2010

Enhanced expression of the high affinity glutamate transporter GLT-1 in C6 glioma cells delays tumour progression in rat.

Exp Neurol 2009 Jul 15;218(1):56-63. Epub 2009 Apr 15.

Laboratory of Experimental Pharmacology, Université catholique de Louvain, 54.10, Av. Hippocrate 54, 1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.expneurol.2009.04.004DOI Listing
July 2009

Nitric oxide delivery to cancer: why and how?

Eur J Cancer 2009 May 17;45(8):1352-69. Epub 2009 Jan 17.

Unit of Pharmacology and Therapeutics, Université catholique de Louvain (UCL), Avenue E. Mounier 52, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.ejca.2008.12.018DOI Listing
May 2009

Rapid monitoring of oxygenation by 19F magnetic resonance imaging: Simultaneous comparison with fluorescence quenching.

Magn Reson Med 2009 Mar;61(3):634-8

Laboratory of Biomedical Magnetic Resonance, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/mrm.21594DOI Listing
March 2009

Electron paramagnetic resonance as a tool to evaluate human ovarian tissue reoxygenation after xenografting.

Fertil Steril 2009 Jul 9;92(1):374-81. Epub 2008 Aug 9.

Department of Gynecology, Faculty of Medicine, Université catholique de Louvain, Louvain, Cliniques Universitaires St. Luc, Avenue Hippocrate 10, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.fertnstert.2008.05.012DOI Listing
July 2009

Thyroid status is a key modulator of tumor oxygenation: implication for radiation therapy.

Radiat Res 2007 Oct;168(4):428-32

Laboratory of Biomedical Magnetic Resonance, Université Catholique de Louvain, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1667/RR0931.1DOI Listing
October 2007

Irradiation promotes Akt-targeting therapeutic gene delivery to the tumor vasculature.

Int J Radiat Oncol Biol Phys 2007 Mar 2;67(4):1155-62. Epub 2007 Feb 2.

Unit of Pharmacology and Therapeutics, Université Catholique de Louvain Medical School, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2006.11.031DOI Listing
March 2007

Glucocorticoids modulate tumor radiation response through a decrease in tumor oxygen consumption.

Clin Cancer Res 2007 Jan;13(2 Pt 1):630-5

Laboratories of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0802DOI Listing
January 2007

Preclinical safety and antitumor efficacy of insulin combined with irradiation.

Radiother Oncol 2006 Oct 15;81(1):112-7. Epub 2006 Sep 15.

Laboratory of Biomedical Magnetic Resonance, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2006.08.023DOI Listing
October 2006

Complex relationship between changes in oxygenation status and changes in R*2: the case of insulin and NS-398, two inhibitors of oxygen consumption.

Magn Reson Med 2006 Sep;56(3):637-43

Laboratory of Biomedical Magnetic Resonance, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/mrm.20963DOI Listing
September 2006

Metabolite changes in HT-29 xenograft tumors following HIF-1alpha inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo.

NMR Biomed 2005 Nov;18(7):430-9

Department of Biochemistry and Molecular Biophysics, Arizona Cancer Center, Tucson, AZ 85724, USA.

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http://dx.doi.org/10.1002/nbm.977DOI Listing
November 2005

Tumor radiosensitization by antiinflammatory drugs: evidence for a new mechanism involving the oxygen effect.

Cancer Res 2005 Sep;65(17):7911-6

Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1288DOI Listing
September 2005

Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment.

Clin Cancer Res 2005 Jan;11(2 Pt 1):743-50

Laboratories of Biomedical Magnetic Resonance, Université Catholique de Louvain, Avenue E. Mounier 73-40, B-1200 Brussels, Belgium.

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January 2005

Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia?

Phys Med Biol 2004 Aug;49(15):3389-411

Laboratory of Biomedical Magnetic Resonance, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1088/0031-9155/49/15/006DOI Listing
August 2004

Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applications.

NMR Biomed 2004 Aug;17(5):240-62

Biomedical Magnetic Resonance Unit and Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Brussels, Belgium.

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http://doi.wiley.com/10.1002/nbm.900
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http://dx.doi.org/10.1002/nbm.900DOI Listing
August 2004

Contribution of oxygenation to BOLD contrast in exercising muscle.

Magn Reson Med 2004 Aug;52(2):391-6

Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/mrm.20155DOI Listing
August 2004

Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment.

Cancer Res 2004 May;64(9):3209-14

University of Louvain Medical School, Unit of Pharmacology and Therapeutics (FATH 5349), Brussels, Belgium.

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http://dx.doi.org/10.1158/0008-5472.can-03-1291DOI Listing
May 2004

Nitric oxide as a radiosensitizer: evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption.

Int J Cancer 2004 May;109(5):768-73

Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Avenue Mounier 73.40, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1002/ijc.20046DOI Listing
May 2004

Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses.

Int J Radiat Oncol Biol Phys 2003 Mar;55(4):1066-73

Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1016/s0360-3016(02)04505-4DOI Listing
March 2003

Potentiation of radiation-induced regrowth delay by isosorbide dinitrate in FSaII murine tumors.

Int J Cancer 2003 Jan;103(1):138-41

Laboratory of Medicinal Chemistry and Radiopharmacy, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1002/ijc.10786DOI Listing
January 2003

Modulation of the tumor vasculature functionality by ionizing radiation accounts for tumor radiosensitization and promotes gene delivery.

FASEB J 2002 Dec 18;16(14):1979-81. Epub 2002 Oct 18.

University of Louvain Medical School, Pharmacology and Therapeutics Unit (FATH 5349), B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1096/fj.02-0487fjeDOI Listing
December 2002

Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption.

Cancer Res 2002 Jun;62(12):3555-61

Laboratory of Medicinal Chemistry and Radiopharmacy, Laboratory of Biomedical Magnetic Resonance, Université Catholique de Louvain, B-1200 Brussels, Belgium.

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June 2002