Benedicte Dubois

Benedicte Dubois

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Benedicte Dubois

Benedicte Dubois

Publications by authors named "Benedicte Dubois"

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Leveraging human genetics to inform intervention strategies for multiple sclerosis.

Neurology 2019 Apr 20;92(16):735-736. Epub 2019 Mar 20.

From the Department of Neurosciences (A.G., B.D.), Laboratory for Neuroimmunology, KU Leuven; Leuven Brain Institute (A.G., B.D.); and Department of Neurology (B.D.), University Hospitals Leuven, Belgium.

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http://dx.doi.org/10.1212/WNL.0000000000007298DOI Listing
April 2019

Genetic basis for relapse rate in multiple sclerosis: Association with LRP2 genetic variation.

Mult Scler 2018 11 5;24(13):1773-1775. Epub 2018 Jan 5.

Department of Neurosciences, Laboratory for Neuroimmunology, KU Leuven, Leuven, Belgium; Department of Neurology, University Hospitals Leuven, Leuven, Belgium.

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http://journals.sagepub.com/doi/10.1177/1352458517749894
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http://dx.doi.org/10.1177/1352458517749894DOI Listing
November 2018

LncRNAs expression profile in peripheral blood mononuclear cells from multiple sclerosis patients.

J Neuroimmunol 2018 11 27;324:129-135. Epub 2018 Aug 27.

University of Milan, Dino Ferrari Center, Milan, Italy; Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2018.08.008DOI Listing
November 2018

Immunologic profiles of multiple sclerosis treatments reveal shared early B cell alterations.

Neurol Neuroimmunol Neuroinflamm 2016 Aug 10;3(4):e240. Epub 2016 May 10.

Department of Immunology and Microbiology (J.D., D.F., J.E.G.-P., D.D.-A., A.T.L.N., A.L.), Laboratory for Neuroimmunology, Department of Neurosciences (I.P., I.S., K.H., B. Dubois, A.G.), Laboratory for Neurobiology, Department of Neurosciences (L.D.M.), Laboratory for Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine (B. Decallonne), and Department of Neurology, University Hospitals Leuven (I.S., J.T., B. Dubois), KU Leuven-University of Leuven; and Center for the Biology of Disease (J.D., D.F., J.E.G.-P., D.D.-A., A.T.L.N., A.L.), VIB (L.D.M.), Leuven, Belgium.

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http://dx.doi.org/10.1212/NXI.0000000000000240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872020PMC
August 2016

Burden of risk variants correlates with phenotype of multiple sclerosis.

Mult Scler 2015 Nov 6;21(13):1670-80. Epub 2015 May 6.

Laboratory for Neuroimmunology, Department of Neurosciences, Experimental Neurology, KU Leuven - University of Leuven, Belgium

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http://dx.doi.org/10.1177/1352458514568174DOI Listing
November 2015

Characteristic callosal involvement in Susac's syndrome.

Acta Neurol Belg 2015 Sep 5;115(3):395-6. Epub 2014 Aug 5.

Department of Neurology, University Hospitals Leuven, Herestraat 49, 3000, Louvain, Belgium,

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http://dx.doi.org/10.1007/s13760-014-0337-4DOI Listing
September 2015

HLA-E restricted CD8+ T cell subsets are phenotypically altered in multiple sclerosis patients.

Mult Scler 2014 06 21;20(7):790-801. Epub 2013 Oct 21.

Biomedical Research Institute, Hasselt University, Belgium

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http://dx.doi.org/10.1177/1352458513509703DOI Listing
June 2014

Frequency of C9orf72 repeat expansions in amyotrophic lateral sclerosis: a Belgian cohort study.

Neurobiol Aging 2013 Dec 17;34(12):2890.e7-2890.e12. Epub 2013 Jul 17.

Department of Neurology, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.06.009DOI Listing
December 2013

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

Rare MEFV variants are not associated with risk to develop multiple sclerosis and severity of disease.

Mult Scler 2013 Aug 16;19(9):1132-6. Epub 2013 Jan 16.

Department of Neurosciences, Laboratory for Neuroimmunology, Section of Experimental Neurology, KU Leuven, Belgium.

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http://dx.doi.org/10.1177/1352458512472749DOI Listing
August 2013

Progress in multiple sclerosis genetics.

Curr Genomics 2012 Dec;13(8):646-63

Laboratory for Neuroimmunology, Section of Experimental Neurology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.2174/138920212803759695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492804PMC
December 2012

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

TNFRSF1A coding variants in multiple sclerosis.

J Neuroimmunol 2011 Jun 11;235(1-2):110-2. Epub 2011 May 11.

Laboratory for Neuroimmunology, Section of Experimental Neurology, Katholieke Universiteit Leuven, Herestraat 49 Bus 1022, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.jneuroim.2011.04.005DOI Listing
June 2011

Autologous and allogeneic hematopoietic stem cell transplantation for Multiple Sclerosis: perspective on mechanisms of action.

J Neuroimmunol 2008 Jul 9;197(2):89-98. Epub 2008 Jun 9.

Laboratory of Experimental Transplantation, University of Leuven, Belgium.

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http://dx.doi.org/10.1016/j.jneuroim.2008.04.030DOI Listing
July 2008

Allogeneic bone marrow transplantation in models of experimental autoimmune encephalomyelitis: evidence for a graft-versus-autoimmunity effect.

Biol Blood Marrow Transplant 2007 Jun 23;13(6):627-37. Epub 2007 Apr 23.

Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.bbmt.2007.03.001DOI Listing
June 2007

Clinical characteristics and long term prognosis in early onset multiple sclerosis.

J Neurol 2006 Jun 6;253(6):720-3. Epub 2006 Mar 6.

University Hospital Gasthuisberg, Department of Neurology, Herestraat 49, 3000 Leuven, Belgium.

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http://link.springer.com/10.1007/s00415-006-0095-1
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http://dx.doi.org/10.1007/s00415-006-0095-1DOI Listing
June 2006

Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression.

J Neurosci Res 2006 Jun;83(8):1432-46

Biomedisch Onderzoeksinstituut and Transnationale Universiteit Limburg, School of Life Sciences, Hasselt University, Diepenbeek, Belgium.

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http://dx.doi.org/10.1002/jnr.20852DOI Listing
June 2006

CD24 Ala/Val polymorphism and multiple sclerosis.

J Neuroimmunol 2006 Jun 2;175(1-2):200-2. Epub 2006 May 2.

Department of Clinical Neurosciences, Neurology Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S016557280600088
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http://dx.doi.org/10.1016/j.jneuroim.2006.03.009DOI Listing
June 2006

Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease.

N Engl J Med 2005 Jul 9;353(4):362-8. Epub 2005 Jun 9.

Division of Gastroenterology, University of Leuven Hospitals, Leuven, Belgium.

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http://dx.doi.org/10.1056/NEJMoa051586DOI Listing
July 2005

New candidate loci for multiple sclerosis susceptibility revealed by a whole genome association screen in a Belgian population.

J Neuroimmunol 2003 Oct;143(1-2):65-9

Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.jneuroim.2003.08.013DOI Listing
October 2003

Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9).

Crit Rev Biochem Mol Biol 2002 Dec;37(6):375-536

Rega Institute for Medical Research, University of Leuven, Belgium.

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http://dx.doi.org/10.1080/10409230290771546DOI Listing
December 2002

Gelatinase B deficiency protects against endotoxin shock.

Eur J Immunol 2002 Aug;32(8):2163-71

Rega Institute, Laboratory of Molecular Immunology, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/1521-4141(200208)32:8<2163::AID-IMMU2163>3.0.CO;2-QDOI Listing
August 2002