Publications by authors named "Ben van Ommen"

100Publications

Current and Future Nutritional Strategies to Modulate Inflammatory Dynamics in Metabolic Disorders.

Front Nutr 2019 26;6:129. Epub 2019 Aug 26.

Department of Microbiology and Systems Biology, Netherlands Organisation for Applied Scientific Research (TNO), Zeist, Netherlands.

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http://dx.doi.org/10.3389/fnut.2019.00129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718105PMC
August 2019

Environmental Forces that Shape Early Development: What We Know and Still Need to Know.

Curr Dev Nutr 2018 Aug 22;2(8):nzx002. Epub 2017 Nov 22.

Department of Human Nutrition, Ohio State University, Columbus, OH.

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http://dx.doi.org/10.3945/cdn.117.001826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111237PMC
August 2018

Postprandial endotoxemia may influence the development of type 2 diabetes mellitus: From the CORDIOPREV study.

Clin Nutr 2019 04 11;38(2):529-538. Epub 2018 Apr 11.

Lipids and Atherosclerosis Unit, GC9 Nutrigenomics, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2018.03.016DOI Listing
April 2019

Determinants of postprandial plasma bile acid kinetics in human volunteers.

Am J Physiol Gastrointest Liver Physiol 2017 Oct 29;313(4):G300-G312. Epub 2017 Jun 29.

Nutrition and Food Sciences, Technische Universität München, Freising-Weihenstephan, Germany.

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http://dx.doi.org/10.1152/ajpgi.00157.2017DOI Listing
October 2017

Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation.

Nutr Rev 2017 05;75(5):307-326

P. Pérez-Martínez, J. Delgado-Lista, A. García-Ríos, F. Pérez-Jiménez, and J. López-Miranda are with the Lipid and Atherosclerosis Unit, IMIBIC/Reina Sofia University Hospital/University of Cordoba, Cordoba, Spain. P. Pérez-Martínez, M. Bullo, M.I. Covas, J. Delgado-Lista, A. Díaz-López, R. Estruch, M. Fitó, A. García-Ríos, G. Mena-Sánchez, A. Muñoz-Garach, F. Pérez-Jiménez, J. Salas-Salvadó, F.J. Tinahones, R. de la Torre, E. Ros, and J. López-Miranda are with the CIBER Fisiopatologia Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. D.P. Mikhailidis is with the Department of Clinical Biochemistry, Royal Free Hospital Campus, University College London Medical School, University College London, London, United Kingdom. V.G. Athyros and N. Katsiki are with the Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece. M. Bullo, A. Díaz-López, G. Mena-Sánchez, and J. Salas-Salvadó are with the Human Nutrition Unit, Biochemistry Biotechnology Department, Faculty of Medicine and Health Sciences, Hospital Universitari de Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, Reus, Spain. P. Couture and B. Lamarche are with the Institute on Nutrition and Functional Foods, Laval University, Quebec, Canada. M.I. Covas, M. Fitó, and H. Schröder are with the Cardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute, Barcelona, Spain. M.I. Covas is with the NUPROAS (Nutritional Project Assessment) Handesbolag, Nacka?, Sweden. L. de Koning is with the the Department of Pathology and Department of Laboratory Medicine, Pediatrics, and Community Health Sciences, University of Calgary, Alberta, Canada. C.A. Drevon is with the Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. R. Estruch is with the Department of Internal Medicine, Hospital Clínic, Institut d'Investigacions Biomédiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain. K. Esposito, D. Giugliano, and M. Ida Maiorino are with the Division of Endocrinology and Metabolic Diseases, Second University of Naples Diabetes Unit, Second University of Naples, Naples, Italy. M. Garaulet is with the Chronobiology Laboratory, Department of Physiology, University of Murcia and Research Biomedical Institute of Murcia, Murcia, Spain. G. Kolovou is with the 1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. A. Muñoz-Garach and F.J. Tinahones are with the Servicio de Endocrinologia y Nutricion, Hospital Clinico Virgen de la Victoria, Malaga, Spain. D. Nikolic and M. Rizzo are with the Biomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy. J.M. Ordovás is with the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University School of Medicine, Boston, Massachusetts, United States. J.M. Ordovás is with the Department of Epidemiology, National Center of Cardiovascular Investigations, Madrid, Spain; and the Madrid Institute of Advanced Studies-Food, Madrid, Spain. H. Schröder is with the CIBER de Epidemiologia y Salud Pública, Madrid, Spain. R. de la Torre is with the Human Pharmacology and Clinical Neurosciences Research Group, Hospital del Mar Research Institute, Barcelona, Spain. B. van Ommen and S. Wopereis are with the Toegepast Natuurwetenschappelijk Onderzoek, Zeist, The Netherlands. E. Ros is with the Lipid Clinic, Endocrinology and Nutrition Service, Institut d'Investigacions Biomédiques August Pi i Sunyer, Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.1093/nutrit/nux014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914407PMC
May 2017

A dysregulation of glucose metabolism control is associated with carotid atherosclerosis in patients with coronary heart disease (CORDIOPREV-DIAB study).

Atherosclerosis 2016 10 16;253:178-185. Epub 2016 Jul 16.

Lipids and Atherosclerosis Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Spain; CIBER Fisiopatologia Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.07.903DOI Listing
October 2016

Metabolomic biomarkers for personalised glucose lowering drugs treatment in type 2 diabetes.

Metabolomics 2016 6;12:27. Epub 2016 Jan 6.

Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Str. 6.131, PO Box 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s11306-015-0930-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703625PMC
January 2016

Next-Generation Biomarkers of Health.

Nestle Nutr Inst Workshop Ser 2016 14;84:25-33. Epub 2016 Jan 14.

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http://dx.doi.org/10.1159/000436949DOI Listing
October 2016

Quantifying phenotypic flexibility as the response to a high-fat challenge test in different states of metabolic health.

FASEB J 2015 Nov 21;29(11):4600-13. Epub 2015 Jul 21.

Microbiology Systems and Biology Group, Netherlands Organisation for Applied Scientific Research (TNO), Zeist, The Netherlands

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http://dx.doi.org/10.1096/fj.14-269852DOI Listing
November 2015

Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations.

J Pharmacokinet Pharmacodyn 2014 Aug 9;41(4):351-62. Epub 2014 Aug 9.

The Netherlands Organization for Applied Scientific Research (TNO), Utrechtseweg 48, P.O. Box 360, 3700 AJ, Zeist, The Netherlands.

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http://dx.doi.org/10.1007/s10928-014-9369-xDOI Listing
August 2014

Lipoprotein metabolism indicators improve cardiovascular risk prediction.

PLoS One 2014 25;9(3):e92840. Epub 2014 Mar 25.

The Nutrition and Genomics Laboratory, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092840PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965475PMC
December 2014

The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: a systems biology approach.

Mech Ageing Dev 2014 Mar-Apr;136-137:138-47. Epub 2014 Jan 23.

TNO, Microbiology and Systems Biology Group, Utrechtseweg 48, 3704 HE Zeist, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2014.01.004DOI Listing
December 2014

Looking back into the future: 30 years of metabolomics at TNO.

Mass Spectrom Rev 2013 Sep-Oct;32(5):399-415. Epub 2013 Apr 29.

TNO, PO Box 360, 6700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1002/mas.21370DOI Listing
March 2014

A physiologically based in silico kinetic model predicting plasma cholesterol concentrations in humans.

J Lipid Res 2012 Dec 29;53(12):2734-46. Epub 2012 Sep 29.

The Netherlands Organization for Applied Scientific Research, 3700 AJ Zeist, The Netherlands.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M031930
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http://dx.doi.org/10.1194/jlr.M031930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494263PMC
December 2012

Public health perspective: from personalized medicine to personal health.

Per Med 2012 Mar;9(2):115-119

Institute for Public Health Genomics, Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.2217/pme.12.16DOI Listing
March 2012

Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice.

Physiol Genomics 2012 Mar 10;44(5):293-304. Epub 2012 Jan 10.

TNO, Research Group Microbiology and Systems Biology, P.O. Box 360, 3700 AJ Zeist, the Netherlands.

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http://dx.doi.org/10.1152/physiolgenomics.00072.2011DOI Listing
March 2012

Diagnostic markers based on a computational model of lipoprotein metabolism.

J Clin Bioinforma 2011 Oct 26;1(1):29. Epub 2011 Oct 26.

TNO Quality of Life, Business Unit Biosciences, Zeist and Leiden, the Netherlands.

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http://jclinbioinformatics.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/2043-9113-1-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305892PMC
October 2011

A dietary mixture containing fish oil, resveratrol, lycopene, catechins, and vitamins E and C reduces atherosclerosis in transgenic mice.

J Nutr 2011 May 16;141(5):863-9. Epub 2011 Mar 16.

The Netherlands Organization for Applied Scientific Research (TNO), Biosciences, 3704 HE, Zeist, The Netherlands.

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http://dx.doi.org/10.3945/jn.110.133751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077889PMC
May 2011

A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse.

Biochim Biophys Acta 2011 May 12;1811(5):333-42. Epub 2011 Feb 12.

The Netherlands Organization for Applied Scientific Research (TNO), Utrechtseweg 48, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1016/j.bbalip.2011.02.002DOI Listing
May 2011

Connecting the Human Variome Project to nutrigenomics.

Genes Nutr 2010 Dec 15;5(4):275-283. Epub 2010 Oct 15.

Genomic Disorders Research Centre, Level 2, Alan Gilbert Building, 161 Barry Street, Melbourne, VIC 3053 Australia.

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http://dx.doi.org/10.1007/s12263-010-0186-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989367PMC
December 2010

Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes.

Biochim Biophys Acta 2010 Jun 20;1801(6):646-54. Epub 2010 Feb 20.

The Netherlands Organization for Applied Scientific Research (TNO) Quality of Life, Utrechtseweg 48, PO Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1016/j.bbalip.2010.02.009DOI Listing
June 2010

Developing computational model-based diagnostics to analyse clinical chemistry data.

Brief Bioinform 2010 Jul 7;11(4):403-16. Epub 2010 Jan 7.

U TNO Quality of Life Research Institute and at Leiden Amsterdam Centre for Drug Research at Leiden University.

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http://dx.doi.org/10.1093/bib/bbp071DOI Listing
July 2010

Filling gaps in PPAR-alpha signaling through comparative nutrigenomics analysis.

BMC Genomics 2009 Dec 11;10:596. Epub 2009 Dec 11.

Department of Pharmacology, University of Firenze, Firenze, Italy.

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http://dx.doi.org/10.1186/1471-2164-10-596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801700PMC
December 2009

Challenging homeostasis to define biomarkers for nutrition related health.

Mol Nutr Food Res 2009 Jul;53(7):795-804

RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen, The Netherlands.

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http://dx.doi.org/10.1002/mnfr.200800390DOI Listing
July 2009

Owner controlled data exchange in nutrigenomic collaborations: the NuGO information network.

Genes Nutr 2009 Jun 30;4(2):113-22. Epub 2009 Apr 30.

Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany,

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http://dx.doi.org/10.1007/s12263-009-0123-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690731PMC
June 2009

Effect of body fat distribution on the transcription response to dietary fat interventions.

Genes Nutr 2009 Jun 30;4(2):143-9. Epub 2009 Apr 30.

TNO Quality of Life, Business Unit Biosciences, P.O. Box 360, 3700 AJ, Zeist, The Netherlands,

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http://dx.doi.org/10.1007/s12263-009-0122-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690730PMC
June 2009

Improving the analysis of designed studies by combining statistical modelling with study design information.

BMC Bioinformatics 2009 Feb 7;10:52. Epub 2009 Feb 7.

Dutch nutrigenomics consortium of the Top Institute Food and Nutrition (TIFN), Wageningen, The Netherlands.

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http://dx.doi.org/10.1186/1471-2105-10-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657790PMC
February 2009

Personalized nutrition from a health perspective: luxury or necessity?

Authors:
Ben van Ommen

Genes Nutr 2007 Oct;2(1):3-4

TNO Quality of Life, European Nutrigenomics Organization, Utrecht, The Netherlands,

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http://genesandnutrition.biomedcentral.com/articles/10.1007/
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http://dx.doi.org/10.1007/s12263-007-0018-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474937PMC
October 2007

The challenges for molecular nutrition research 3: comparative nutrigenomics research as a basis for entering the systems level.

Genes Nutr 2008 Dec 1;3(3-4):101-6. Epub 2008 Oct 1.

Molecular Nutrition Unit, Nutrition and Food Research Center, Technische Universität München, Freising, Germany,

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http://link.springer.com/10.1007/s12263-008-0089-y
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http://dx.doi.org/10.1007/s12263-008-0089-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593016PMC
December 2008

The challenges for molecular nutrition research 4: the "nutritional systems biology level".

Genes Nutr 2008 Dec 30;3(3-4):107-13. Epub 2008 Sep 30.

Department of Biosciences, TNO-Quality of Life, Zeist, The Netherlands,

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http://dx.doi.org/10.1007/s12263-008-0090-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593015PMC
December 2008

A network biology model of micronutrient related health.

Br J Nutr 2008 Jun;99 Suppl 3:S72-80

TNO Quality of Life, PO box 360, 4700 AJ Zeist, The Netherlands.

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http://www.journals.cambridge.org/abstract_S0007114508006922
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http://dx.doi.org/10.1017/S0007114508006922DOI Listing
June 2008

Personalised nutrition: status and perspectives.

Br J Nutr 2007 Jul 23;98(1):26-31. Epub 2007 Mar 23.

German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, Nuthetal, Germany.

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http://dx.doi.org/10.1017/S0007114507685195DOI Listing
July 2007

The introduction of toxicogenomics; potential new markers of hepatotoxicity.

Cancer Biomark 2005 ;1(1):41-57

TNO Nutrition and Food Research, Zeist, The Netherlands.

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http://dx.doi.org/10.3233/cbm-2005-1106DOI Listing
February 2007

High-protein and high-carbohydrate breakfasts differentially change the transcriptome of human blood cells.

Am J Clin Nutr 2006 Nov;84(5):1233-41

TNO Quality of Life, Zeist, Netherlands, and Wageningen University, Wageningen, The Netherlands.

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https://academic.oup.com/ajcn/article/84/5/1233/4649109
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http://dx.doi.org/10.1093/ajcn/84.5.1233DOI Listing
November 2006

Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach.

Drug Metab Dispos 2006 Dec 8;34(12):2083-90. Epub 2006 Sep 8.

Business Unit Biosciences, TNO Quality of Life (Netherlands Organization for Applied Scientific Research), Physiological Genomics, Zeist, The Netherlands.

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http://dx.doi.org/10.1124/dmd.106.011262DOI Listing
December 2006

Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation.

Anal Chem 2006 Jan;78(2):567-74

Business Unit Analytical Sciences and Business Unit Physiological Sciences, TNO Quality of Life, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

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http://pubs.acs.org/doi/abs/10.1021/ac051495j
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http://dx.doi.org/10.1021/ac051495jDOI Listing
January 2006

The case for strategic international alliances to harness nutritional genomics for public and personal health.

Br J Nutr 2005 Nov;94(5):623-32

Center of Excellence in Nutritional Genomics, University of California, Davis, CA 95616, USA.

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http://repositorio.uchile.cl/bitstream/handle/2250/123828/Ka
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http://dx.doi.org/10.1079/bjn20051585DOI Listing
November 2005

Nutrigenomics: the impact of biomics technology on nutrition research.

Ann Nutr Metab 2005 Nov-Dec;49(6):355-65. Epub 2005 Sep 21.

Centre de Recherche Nestlé, Département de Nutrition, Lausanne, Switzerland.

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http://dx.doi.org/10.1159/000088315DOI Listing
January 2006

Metabolomics in human nutrition: opportunities and challenges.

Am J Clin Nutr 2005 Sep;82(3):497-503

Nutrition Unit, Department of Clinical Medicine, Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1093/ajcn.82.3.497DOI Listing
September 2005

Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals.

Toxicol Appl Pharmacol 2005 Sep;207(2 Suppl):179-88

Physiological Sciences Department, TNO Quality of Life, Zeist, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S0041008X0500328
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http://dx.doi.org/10.1016/j.taap.2005.01.050DOI Listing
September 2005

Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2.

Cancer Lett 2006 Jul 29;238(2):248-59. Epub 2005 Aug 29.

Physiological Sciences Department, TNO Quality of Life, Zeist, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S030438350500663
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http://dx.doi.org/10.1016/j.canlet.2005.07.007DOI Listing
July 2006

Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis.

Toxicol Pathol 2005 ;33(4):425-33

TNO Nutrition and Food Research, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1080/01926230590958146DOI Listing
September 2005

Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure.

Mutat Res 2005 Aug;575(1-2):85-101

TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ Zeist, The Netherlands.

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http://dx.doi.org/10.1016/j.mrfmmm.2005.02.003DOI Listing
August 2005

Nutrigenomics in efficacy and safety evaluation of food components.

World Rev Nutr Diet 2004 ;93:134-52

TNO Nutrition and Food Research, Zeist, The Netherlands.

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http://dx.doi.org/10.1159/000081256DOI Listing
December 2004

Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells.

J Carcinog 2004 May 12;3(1). Epub 2004 May 12.

Wageningen University, Division of Toxicology, Tuinlaan 5, 6703 HE Wageningen, the Netherlands.

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http://dx.doi.org/10.1186/1477-3163-3-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC421747PMC
May 2004