Publications by authors named "Ben Van Calster"

100Publications

Methodological Issues in the Development of a Prediction Tool for First-Trimester Outcomes.

J Ultrasound Med 2020 Oct 24. Epub 2020 Oct 24.

Center for Biostatistics, Division of Population Health, Health Services Research, and Primary Care, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jum.15543DOI Listing
October 2020

Demystifying AI in healthcare.

BMJ 2020 09 9;370:m3505. Epub 2020 Sep 9.

Department of Development and Regeneration, KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.m3505DOI Listing
September 2020

ROC curves for clinical prediction models part 1. ROC plots showed no added value above the AUC when evaluating the performance of clinical prediction models.

J Clin Epidemiol 2020 Oct 23;126:207-216. Epub 2020 Jul 23.

Department of Biomedical Data Sciences, Leiden University Medical Centre (LUMC), Leiden, the Netherlands; KU Leuven, Department of Development and Regeneration, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2020.01.028DOI Listing
October 2020

ROC curves for clinical prediction models part 3. The ROC plot: a picture that needs a 1000 words.

J Clin Epidemiol 2020 Oct 18;126:220-223. Epub 2020 Jun 18.

Department of Biomedical Data Sciences, Leiden University Medical Centre (LUMC), Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2020.05.037DOI Listing
October 2020

Regression shrinkage methods for clinical prediction models do not guarantee improved performance: Simulation study.

Stat Methods Med Res 2020 11 13;29(11):3166-3178. Epub 2020 May 13.

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0962280220921415DOI Listing
November 2020

Redefining significance and reproducibility for medical research: A plea for higher P-value thresholds for diagnostic and prognostic models.

Eur J Clin Invest 2020 May 9;50(5):e13229. Epub 2020 May 9.

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/eci.13229DOI Listing
May 2020

Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury.

J Clin Epidemiol 2020 Jun 20;122:95-107. Epub 2020 Mar 20.

Departments of Public Health, Erasmus MC - University Medical Centre Rotterdam, Rotterdam, the Netherlands; Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2020.03.005DOI Listing
June 2020

Posttraumatic stress, anxiety and depression following miscarriage and ectopic pregnancy: a multicenter, prospective, cohort study.

Am J Obstet Gynecol 2020 04 13;222(4):367.e1-367.e22. Epub 2019 Dec 13.

Tommy's National Centre for Miscarriage Research, Queen Charlottes and Chelsea Hospital, Imperial College, London, UK; KU Leuven, Department of Development and Regeneration, Leuven, Belgium; Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2019.10.102DOI Listing
April 2020

Calibration: the Achilles heel of predictive analytics.

BMC Med 2019 12 16;17(1):230. Epub 2019 Dec 16.

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12916-019-1466-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912996PMC
December 2019

Changing predictor measurement procedures affected the performance of prediction models in clinical examples.

J Clin Epidemiol 2020 03 9;119:7-18. Epub 2019 Nov 9.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands; Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2019.11.001DOI Listing
March 2020

Three myths about risk thresholds for prediction models.

BMC Med 2019 10 25;17(1):192. Epub 2019 Oct 25.

KU Leuven Department of Development and Regeneration, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12916-019-1425-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814132PMC
October 2019

A simple, step-by-step guide to interpreting decision curve analysis.

Diagn Progn Res 2019 4;3:18. Epub 2019 Oct 4.

3Department of Biomedical Data Sciences, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s41512-019-0064-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777022PMC
October 2019

Statistics versus machine learning: definitions are interesting (but understanding, methodology, and reporting are more important).

J Clin Epidemiol 2019 12 16;116:137-138. Epub 2019 Aug 16.

Centre for Statistics in Medicine, Botnar Research Centre, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2019.08.002DOI Listing
December 2019

Predictive analytics in health care: how can we know it works?

J Am Med Inform Assoc 2019 12;26(12):1651-1654

Centre for Statistics in Medicine, Nuffield, Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jamia/ocz130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857503PMC
December 2019

Machine Learning in Medicine.

N Engl J Med 2019 06;380(26):2588

Maastricht University, Maastricht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1906060DOI Listing
June 2019

Regarding A Nomogram to Predict Osteoradionecrosis in Oral Cancer After Marginal Mandibulectomy and Radiotherapy.

Laryngoscope 2019 10 31;129(10):E343. Epub 2019 May 31.

KU Leuven, Department of Development and Regeneration, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/lary.28089DOI Listing
October 2019

Artificial Intelligence Algorithms for Medical Prediction Should Be Nonproprietary and Readily Available.

JAMA Intern Med 2019 05;179(5):731

Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamainternmed.2019.0597DOI Listing
May 2019

A systematic review shows no performance benefit of machine learning over logistic regression for clinical prediction models.

J Clin Epidemiol 2019 06 11;110:12-22. Epub 2019 Feb 11.

Department of Development & Regeneration, KU Leuven, Herestraat 49 box 805, Leuven, 3000 Belgium; Department of Biomedical Data Sciences, Leiden University Medical Centre, Albinusdreef 2, Leiden, 2333 ZA The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2019.02.004DOI Listing
June 2019

Sample size considerations and predictive performance of multinomial logistic prediction models.

Stat Med 2019 04 6;38(9):1601-1619. Epub 2019 Jan 6.

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.8063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590172PMC
April 2019

Reporting and Interpreting Decision Curve Analysis: A Guide for Investigators.

Eur Urol 2018 12 19;74(6):796-804. Epub 2018 Sep 19.

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands; Department of Public Health, Erasmus MC, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2018.08.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261531PMC
December 2018

An ordinal prediction model of the diagnosis of non-obstructive coronary artery and multi-vessel disease in the CARDIIGAN cohort.

Int J Cardiol 2018 Sep 24;267:8-12. Epub 2018 May 24.

Department of Biomedical Data Sciences, Leiden University Medical Centre, The Netherlands; Department of Development and Regeneration, KU, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01675273183220
Publisher Site
http://dx.doi.org/10.1016/j.ijcard.2018.05.092DOI Listing
September 2018

Machine Learning Compared With Pathologist Assessment.

JAMA 2018 04;319(16):1725-1726

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2018.1466DOI Listing
April 2018

Are the current guidelines for surgical delay in hip fractures too rigid? A single center assessment of mortality and economics.

Injury 2018 Jun 27;49(6):1169-1175. Epub 2018 Mar 27.

KU Leuven - University of Leuven, Department of Development and Regeneration, B-3000 Leuven, Belgium; University Hospitals Leuven, Department of Trauma Surgery, B-3000 Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.injury.2018.03.032DOI Listing
June 2018

Consequences of relying on statistical significance: Some illustrations.

Eur J Clin Invest 2018 May 28;48(5):e12912. Epub 2018 Feb 28.

Institute for Media Studies, KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/eci.12912DOI Listing
May 2018

Oncological management and obstetric and neonatal outcomes for women diagnosed with cancer during pregnancy: a 20-year international cohort study of 1170 patients.

Lancet Oncol 2018 03 26;19(3):337-346. Epub 2018 Jan 26.

Department of Oncology, KU Leuven, Leuven, Belgium; Division of Gynaecologic Oncology, University Hospitals Leuven, Leuven, Belgium; Center for Gynaecologic Oncology Amsterdam, Antoni van Leeuwenhoek-Netherlands Cancer Institute, Amsterdam, Netherlands; Centre for Gynaecologic Oncology Amsterdam, Academical Medical Center, Amsterdam, Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(18)30059-7DOI Listing
March 2018

Poor performance of clinical prediction models: the harm of commonly applied methods.

J Clin Epidemiol 2018 06 24;98:133-143. Epub 2017 Nov 24.

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands; Department of Development and Regeneration, KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2017.11.013DOI Listing
June 2018

Erratum to: Methods for evaluating medical tests and biomarkers.

Authors:
Gowri Gopalakrishna Miranda Langendam Rob Scholten Patrick Bossuyt Mariska Leeflang Anna Noel-Storr James Thomas Iain Marshall Byron Wallace Penny Whiting Clare Davenport Mariska Leeflang Gowri GopalaKrishna Isabel de Salis Sue Mallett Robert Wolff Penny Whiting Richard Riley Marie Westwood Jos Kleinen Gary Collins Hans Reitsma Karel Moons Antonia Zapf Annika Hoyer Katharina Kramer Oliver Kuss J Ensor J J Deeks E C Martin R D Riley Gerta Rücker Susanne Steinhauser Martin Schumacher Richard Riley Joie Ensor Kym Snell Brian Willis Thomas Debray Karel Moons Jon Deeks Gary Collins Lavinia Ferrante di Ruffano Brian Willis Clare Davenport Sue Mallett Sian Taylor-Phillips Chris Hyde Jon Deeks Sue Mallett Stuart A Taylor Gauraang Batnagar Sian Taylor-Phillips Lavinia Ferrante Di Ruffano Farah Seedat Aileen Clarke Jon Deeks Sarah Byron Frances Nixon Rebecca Albrow Thomas Walker Carla Deakin Chris Hyde Zhivko Zhelev Harriet Hunt Lavinia Ferrante di Ruffano Yaling Yang Lucy Abel James Buchanan Thomas Fanshawe Bethany Shinkins Laure Wynants Jan Verbakel Sabine Van Huffel Dirk Timmerman Ben Van Calster Mariska Leeflang Aeliko Zwinderman Patrick Bossuyt Jason Oke Jack O'Sullivan Rafael Perera Brian Nicholson Hannah L Bromley Tracy E Roberts Adele Francis Denniis Petrie G Bruce Mann Kinga Malottki Holly Smith Jon Deeks Lucinda Billingham Alice Sitch Sue Mallett Jon Deeks Oke Gerke Mie Holm-Vilstrup Eivind Antonsen Segtnan Ulrich Halekoh Poul Flemming Høilund-Carlsen Bernard G Francq Jon Deeks Alice Sitch Jac Dinnes Julie Parkes Walter Gregory Jenny Hewison Doug Altman William Rosenberg Peter Selby Julien Asselineau Paul Perez Aïssatou Paye Emilie Bessede Cécile Proust-Lima Christiana Naaktgeboren Joris de Groot Anne Rutjes Patrick Bossuyt Johannes Reitsma Karel Moons Gary Collins Emmanuel Ogundimu Jonathan Cook Yannick Le Manach Doug Altman Laure Wynants Yvonne Vergouwe Sabine Van Huffel Dirk Timmerman Ben Van Calster Romin Pajouheshnia Rolf Groenwold Karen Moons Johannes Reitsma Linda Peelen Ben Van Calster Daan Nieboer Yvonne Vergouwe Bavo De Cock Micael J Pencina Ewout W Steyerberg Jennifer Cooper Sian Taylor-Phillips Nick Parsons Chris Stinton Steve Smith Andy Dickens Rachel Jordan Alexandra Enocson David Fitzmaurice Alice Sitch Peymane Adab Bernard G Francq Charles Boachie Gaj Vidmar Karoline Freeman Martin Connock Sian Taylor-Phillips Rachel Court Aileen Clarke Joris de Groot Christiana Naaktgeboren Hans Reitsma Carl Moons Jessica Harris Andrew Mumford Zoe Plummer Kurtis Lee Barnaby Reeves Chris Rogers Veerle Verheyden Gianni D Angelini Gavin J Murphy Jeremy Huddy Melody Ni Katherine Good Graham Cooke Patrick Bossuyt George Hanna Jie Ma Doug Altman Gary Collins K G M Carl Moons Joris A H de Groot Sue Mallett Doug G Altman Johannes B Reitsma Gary S Collins Karel G M Moons Douglas G Altman Johannes B Reitsma Gary S Collins Adina Najwa Kamarudin Ruwanthi Kolamunnage-Dona Trevor Cox Melody Ni Jeremy Huddy Simone Borsci George Hanna Teresa Pérez M Carmen Pardo Angel Candela-Toha Alfonso Muriel Javier Zamora Sabina Sanghera Syed Mohiuddin Richard Martin Jenny Donovan Joanna Coast Mikyung Kelly Seo John Cairns Elizabeth Mitchell Alison Smith Judy Wright Peter Hall Michael Messenger Nicola Calder Nyantara Wickramasekera Karen Vinall-Collier Andrew Lewington Romin Pajouheshnia Johanna Damen Rolf Groenwold Karel Moons Linda Peelen Michael Messenger David Cairns Alison Smith Michelle Hutchinson Judy Wright Peter Hall Nicola Calder Cathie Sturgeon Liz Mitchel Rebecca Kift Sofia Christakoudi Manohursingh Rungall Paula Mobillo Rosa Montero Tjir-Li Tsui Sui Phin Kon Beatriz Tucker Steven Sacks Chris Farmer Terry Strom Paramit Chowdhury Irene Rebollo-Mesa Maria Hernandez-Fuentes Johanna A A G Damen Thomas P A Debray Pauline Heus Lotty Hooft Karel G M Moons Romin Pajouheshnia Johannes B Reitsma Rob J P M Scholten Johanna A A G Damen Lotty Hooft Ewoud Schuit Thomas P A Debray Gary S Collins Ioanna Tzoulaki Camille M Lassale George C M Siontis Virginia Chiocchia Corran Roberts Michael Maia Schlüssel Stephen Gerry James A Black Pauline Heus Yvonne T van der Schouw Linda M Peelen Karel G M Moons Johanna A A G Damen Thomas P A Debray Pauline Heus Lotty Hooft Karel G M Moons Romin Pajouheshnia Johannes B Reitsma Rob J P M Scholten Jie Ma Doug Altman Gary Collins Graeme Spence David McCartney Ann van den Bruel Daniel Lasserson Gail Hayward Werner Vach Antoinette de Jong Coreline Burggraaff Otto Hoekstra Josée Zijlstra Henrica de Vet Harriet Hunt Chris Hyde Sara Graziadio Joy Allen Louise Johnston Rachel O'Leary Michael Power Joy Allen Sara Graziadio Louise Johnson Rachel O'Leary Michael Power Ray Waters John Simpson Louise Johnston Joy Allen Sara Graziadio Rachel O'Leary Ray Waters Michael Power Sue Mallett Thomas R Fanshawe Peter Phillips Andrew Plumb Emma Helbren Steve Halligan Stuart A Taylor Alastair Gale Sue Mallett Peggy Sekula Douglas G Altman Willi Sauerbrei Sue Mallett Thomas R Fanshawe Julia R Forman Susan J Dutton Yemisi Takwoingi Elizabeth M Hensor Thomas E Nichols Bethany Shinkins Yaling Yang Lucy Abel Lavinia Ferrante Di Ruffano Thomas Fanshawe Emmanuelle Kempf Raphael Porcher Jennifer de Beyer Karel Moons Douglas Altman Hans Reitsma Sally Hopewell Willi Sauerbrei Gary Collins John Dennis Beverley Shields Angus Jones William Henley Ewan Pearson Andrew Hattersley Pauline Heus Johanna A A G Damen Romin Pajouheshnia Rob J P M Scholten Johannes B Reitsma Gary S Collins Douglas G Altman Karel G M Moons Lotty Hooft Beverley Shields John Dennis Angus Jones William Henley Ewan Pearson Andrew Hattersley Fueloep Scheibler Anne Rummer Sibylle Sturtz Robert Großelfinger Katie Banister Craig Ramsay Augusto Azuara-Blanco Jonathan Cook Charles Boachie Jennifer Burr Manjula Kumarasamy Rupert Bourne Ijeoma Uchegbu Simone Borsci Jennifer Murphy George Hanna Ijeoma Uchegbu Alex Carter Jen Murphy Melody Ni Joachim Marti Julie Eatock Ijeoma Uchegbu Julie Robotham Maria Dudareva Mark Gilchrist Alison Holmes Ijeoma Uchegbu Simone Borsci Phillip Monaghan Sarah Lord Andrew StJohn Sverre Sandberg Christa Cobbaert Lieselotte Lennartz Wilma Verhagen-Kamerbeek Christoph Ebert Patrick Bossuyt Andrea Horvath Kevin Jenniskens Christiana Naaktgeboren Johannes Reitsma Karel Moons Joris de Groot Chris Hyde Jaime Peters Bogdan Grigore Jaime Peters Chris Hyde Chris Hyde Obi Ukoumunne Jaime Peters Zhivko Zhelev Brooke Levis Andrea Benedetti Alexander W Levis John P A Ioannidis Ian Shrier Pim Cuijpers Simon Gilbody Lorie A Kloda Dean McMillan Scott B Patten Russell J Steele Roy C Ziegelstein Charles H Bombardier Flavia de Lima Osório Jesse R Fann Dwenda Gjerdingen Femke Lamers Manote Lotrakul Sonia R Loureiro Bernd Löwe Juwita Shaaban Lesley Stafford Henk C P M van Weert Mary A Whooley Linda S Williams Karin A Wittkampf Albert S Yeung Brett D Thombs Jaime Peters Chris Cooper James Buchanan Tom Nieto Claire Smith Olga Tucker Janine Dretzke Andrew Beggs Nirmala Rai Clare Davenport Sue Bayliss Simon Stevens Kym Snell Sue Mallet Jon Deeks Sudha Sundar Emma Hall Nuria Porta David Lorente Estelles Johann de Bono

Diagn Progn Res 2017 30;1:11. Epub 2017 Mar 30.

278The Institute of Cancer Research, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s41512-017-0011-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460744PMC
March 2017

Nonparametric estimation and inference for polytomous discrimination index.

Stat Methods Med Res 2018 10 9;27(10):3092-3103. Epub 2017 Feb 9.

7 University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0962280217692830DOI Listing
October 2018

Validation and updating of risk models based on multinomial logistic regression.

Diagn Progn Res 2017 8;1. Epub 2017 Feb 8.

2Department of Public Health, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s41512-016-0002-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457140PMC
February 2017

Decision Curves, Calibration, and Subgroups.

J Clin Oncol 2017 02 14;35(4):472-473. Epub 2016 Nov 14.

Andrew J. Vickers, Memorial Sloan Kettering Cancer Center, New York, NY; Ben Van Calster, Katholieke Universiteit Leuven, Leuven, Belgium; and Ewout Steyerberg, Erasmus Medical Center, Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.69.1576DOI Listing
February 2017

Explaining Support Vector Machines: A Color Based Nomogram.

PLoS One 2016 10;11(10):e0164568. Epub 2016 Oct 10.

Department of Applied Mathematics, Liverpool John Moores University, Liverpool, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164568PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056733PMC
April 2017

An evidence-based laparoscopic simulation curriculum shortens the clinical learning curve and reduces surgical adverse events.

Adv Med Educ Pract 2016 30;7:357-70. Epub 2016 Jun 30.

Centre for Surgical Technologies, KU Leuven, Leuven, Belgium; Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/AMEP.S102000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962760PMC
August 2016

Intellectual development of childhood ALL patients: a multicenter longitudinal study.

Psychooncology 2017 04 20;26(4):508-514. Epub 2016 Jun 20.

University Hospitals Leuven, Department of Pediatric Hematology and Oncology, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pon.4186DOI Listing
April 2017

Morcellation and risk of malignancy in presumed ovarian fibromas/fibrothecomas.

Lancet Oncol 2016 Mar 2;17(3):273-274. Epub 2016 Mar 2.

Department of Development and Regeneration and Department of Oncology, KU Leuven, Leuven, Belgium; Department of Gynaecology and Obstetrics and Leuven Cancer Institute, University Hospitals KU Leuven, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(16)00022-XDOI Listing
March 2016

Net benefit approaches to the evaluation of prediction models, molecular markers, and diagnostic tests.

BMJ 2016 Jan 25;352:i6. Epub 2016 Jan 25.

Department of Public Health, Erasmus MC, 's-Gravendijkwal, Rotterdam, Netherlands.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724785PMC
http://dx.doi.org/10.1136/bmj.i6DOI Listing
January 2016

A calibration hierarchy for risk models was defined: from utopia to empirical data.

J Clin Epidemiol 2016 06 6;74:167-76. Epub 2016 Jan 6.

Department of Public Health, Erasmus MC, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2015.12.005DOI Listing
June 2016

Authors' reply to Fountain and colleagues.

BMJ 2015 Nov 4;351:h5852. Epub 2015 Nov 4.

Department of Development and Regeneration, KU Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.h5852DOI Listing
November 2015

Risk Prediction for Individuals.

JAMA 2015 Nov;314(17):1875

Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2015.12215DOI Listing
November 2015

Defining safe criteria to diagnose miscarriage: prospective observational multicentre study.

BMJ 2015 Sep 23;351:h4579. Epub 2015 Sep 23.

Queen Charlotte's and Chelsea Hospital, Imperial College, London W12 0HS, UK Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium Department of Development and Regeneration, KU Leuven, Belgium

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580727PMC
http://dx.doi.org/10.1136/bmj.h4579DOI Listing
September 2015

Visualizing Risk Prediction Models.

PLoS One 2015 15;10(7):e0132614. Epub 2015 Jul 15.

KU Leuven, Department of Development and Regeneration, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132614PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503430PMC
April 2016

Improving patient prostate cancer risk assessment: Moving from static, globally-applied to dynamic, practice-specific risk calculators.

J Biomed Inform 2015 Aug 16;56:87-93. Epub 2015 May 16.

TU München, Department of Mathematics, Munich, Germany; HelmholtzZentrum München, Institute of Computational Biology, Munich, Germany; University of Texas Health Science Center at San Antonio, Department of Urology, San Antonio, TX, USA; University of Texas Health Science Center at San Antonio, Department of Epidemiology and Biostatistics, San Antonio, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbi.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532612PMC
August 2015

Authors' reply to Candido-dos-Reis.

BMJ 2014 Nov 18;349:g6691. Epub 2014 Nov 18.

Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.g6691DOI Listing
November 2014

Calibration of risk prediction models: impact on decision-analytic performance.

Med Decis Making 2015 02 25;35(2):162-9. Epub 2014 Aug 25.

Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY (AJV).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0272989X14547233DOI Listing
February 2015

Graphical assessment of incremental value of novel markers in prediction models: From statistical to decision analytical perspectives.

Biom J 2015 Jul 18;57(4):556-70. Epub 2014 Jul 18.

Department of Biostatistics and Bioinformatics, Duke Clinical Research Institute, Duke University, Durham, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201300260DOI Listing
July 2015

Net reclassification improvement and integrated discrimination improvement require calibrated models: relevance from a marker and model perspective.

Stat Med 2014 Aug;33(19):3415-8

Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Cardiology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.6133DOI Listing
August 2014

Prognostic value of serum HE4 levels and risk of ovarian malignancy algorithm scores at the time of ovarian cancer diagnosis.

Int J Gynecol Cancer 2014 Sep;24(7):1173-80

Departments of *Department of Development and Regeneration, KU Leuven, Leuven, Belgium; †Department of Obstetrics and Gynecology, and ‡Leuven Cancer Institute, University Hospital KU Leuven, Leuven, Belgium; §Department of Electrical Engineering (ESAT) and ∥iMinds Future Health Department, KU Leuven, Leuven, Belgium; ¶Department of Obstetrics and Gynecology, Maastricht UMC+, #GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands; and **Department of Surgery and Cancer, Queen Charlotte's & Chelsea Hospital, Imperial College, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IGC.0000000000000181DOI Listing
September 2014

Integrating pretreatment diffusion weighted MRI into a multivariable prognostic model for head and neck squamous cell carcinoma.

Radiother Oncol 2014 Mar 11;110(3):429-34. Epub 2014 Mar 11.

Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2014.01.004DOI Listing
March 2014

Risk prediction with machine learning and regression methods.

Biom J 2014 Jul 25;56(4):601-6. Epub 2014 Feb 25.

Department of Public Health, Erasmus MC, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201300297DOI Listing
July 2014

Assessing calibration of multinomial risk prediction models.

Stat Med 2014 Jul 18;33(15):2585-96. Epub 2014 Feb 18.

KU Leuven Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing, and Data Analytics, Leuven, Belgium; KU Leuven iMinds Future Health Department, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.6114DOI Listing
July 2014

Sensitivity and specificity can change in opposite directions when new predictive markers are added to risk models.

Med Decis Making 2014 05 30;34(4):513-22. Epub 2013 Dec 30.

Department of Biostatistics, Boston University, Boston, MA (BVC, RBD, MJP)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0272989X13513654DOI Listing
May 2014

Presurgical diagnosis of adnexal tumours using mathematical models and scoring systems: a systematic review and meta-analysis.

Hum Reprod Update 2014 May-Jun;20(3):449-62. Epub 2013 Dec 9.

Department of Development and Regeneration, KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/humupd/dmt059DOI Listing
September 2014

Reply to D. Crivellari et al.

J Clin Oncol 2014 Jan 2;32(3):255-6. Epub 2013 Dec 2.

Multidisciplinary Breast Centre, Leuven Cancer Institute, University Hospitals Leuven; Katholieke Universiteit Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2013.53.1012DOI Listing
January 2014

Prognostic impact of baseline serum C-reactive protein in patients with metastatic renal cell carcinoma (RCC) treated with sunitinib.

BJU Int 2014 Jul 15;114(1):81-9. Epub 2014 Jan 15.

Department of General Medical Oncology and Laboratory for Experimental Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium; Inserm U674 Génomique fonctionnelle des tumeurs solides, Université Paris-5 René Descartes, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bju.12494DOI Listing
July 2014

Screening for data clustering in multicenter studies: the residual intraclass correlation.

BMC Med Res Methodol 2013 Oct 23;13:128. Epub 2013 Oct 23.

KU Leuven Department of Development and Regeneration, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2288-13-128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819732PMC
October 2013

A pictorial essay on fetal rabbit anatomy using micro-ultrasound and magnetic resonance imaging.

Prenat Diagn 2014 Jan 22;34(1):84-9. Epub 2013 Nov 22.

Organ systems cluster, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; Center for Surgical Technologies, KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pd.4259DOI Listing
January 2014

Simple dichotomous updating methods improved the validity of polytomous prediction models.

J Clin Epidemiol 2013 Oct 9;66(10):1158-65. Epub 2013 Jul 9.

Department of Electrical Engineering ESAT-SCD, KU Leuven-University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2013.04.014DOI Listing
October 2013

Triple negative breast cancer: clinical characteristics in the different histological subtypes.

Breast 2013 Oct 15;22(5):761-6. Epub 2013 Feb 15.

Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.breast.2013.01.009DOI Listing
October 2013

[Discriminative ability, reclassification and net benefit: the predictive value of biomarkers].

Ned Tijdschr Geneeskd 2012 ;156(41):A5029

Erasmus MC, afd. Maatschappelijke Gezondheidszorg, Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
December 2012

Assessing the discriminative ability of risk models for more than two outcome categories.

Eur J Epidemiol 2012 Oct 7;27(10):761-70. Epub 2012 Oct 7.

Department of Development and Regeneration, KU Leuven, University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-012-9733-3DOI Listing
October 2012

Key findings from the International Ovarian Tumor Analysis (IOTA) study: an approach to the optimal ultrasound based characterisation of adnexal pathology.

Australas J Ultrasound Med 2012 Aug 31;15(3):82-86. Epub 2015 Dec 31.

Department of Obstetrics and GynaecologyUniversity Hospital LeuvenLeuvenBelgium; Academic Department of Development and RegenerationKULeuvenBelgium.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/j.2205-0140.2012.tb00011.x
Publisher Site
http://dx.doi.org/10.1002/j.2205-0140.2012.tb00011.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025098PMC
August 2012

Extending the c-statistic to nominal polytomous outcomes: the Polytomous Discrimination Index.

Stat Med 2012 Oct 26;31(23):2610-26. Epub 2012 Jun 26.

Department of Reproduction, Development, and Regeneration, KU Leuven - University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.5321DOI Listing
October 2012

Discrimination ability of prediction models for ordinal outcomes: relationships between existing measures and a new measure.

Biom J 2012 Sep 19;54(5):674-85. Epub 2012 Jun 19.

Department of Development, and Regeneration, KU Leuven--University of Leuven, Herestraat 49 box 7003, B-3000 Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201200026DOI Listing
September 2012

Pelvic exenterations for gynecological malignancies: a study of 36 cases.

Int J Gynecol Cancer 2012 Jun;22(5):889-96

Division of Gynaecological Oncology, Department of Obstetrics and Gynaecology, and Leuven Cancer Institute, University Hospitals of Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IGC.0b013e31824eb8cdDOI Listing
June 2012

Characterizing ovarian pathology: refining the performance of ultrasonography.

Int J Gynecol Cancer 2012 May;22 Suppl 1:S9-11

Department of Gynecology and Obstetrics, University Hospital KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IGC.0b013e318251c9dfDOI Listing
May 2012

Histology obtained by needle biopsy gives additional information on the prognosis of hepatocellular carcinoma.

Hepatol Res 2012 Oct 30;42(10):990-8. Epub 2012 Apr 30.

Departments of Hepatology Pathology Radiology Biostatistics Cell, Leuvens KankerinstituutDepartments of Abdominal Surgery Abdominal Transplant Surgery, University Hospital Leuven Department of Electrical Engineering (ESAT), Catholic University Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1872-034X.2012.01010.xDOI Listing
October 2012

Evaluating a new marker for risk prediction using the test tradeoff: an update.

Int J Biostat 2012 Mar 22;8(1). Epub 2012 Mar 22.

National Cancer Institute, Bethesda, NIH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/1557-4679.1395DOI Listing
March 2012

The independent effect of tumor size in predicting ovarian malignancy.

Eur J Obstet Gynecol Reprod Biol 2012 Jun 20;162(2):237-8. Epub 2012 Mar 20.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejogrb.2012.02.023DOI Listing
June 2012

Role of neoadjuvant chemotherapy in the management of stage IIIC-IV ovarian cancer: survey results from the members of the European Society of Gynecological Oncology.

Int J Gynecol Cancer 2012 Mar;22(3):407-16

Leuven Cancer Institute, Division of Gynaecological Oncology, Department of Obstetrics and Gynaecology, University Leuven, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IGC.0b013e31823ea1d8DOI Listing
March 2012

Subjective assessment by ultrasound is superior to the risk of malignancy index (RMI) or the risk of ovarian malignancy algorithm (ROMA) in discriminating benign from malignant adnexal masses.

Eur J Cancer 2012 Jul 5;48(11):1649-56. Epub 2012 Jan 5.

Department of Obstetrics and Gynaecology, Leuven Cancer Institute, Universitaire Ziekenhuizen Leuven, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2011.12.003DOI Listing
July 2012