Ben Readhead

Ben Readhead

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Ben Readhead

Ben Readhead

Publications by authors named "Ben Readhead"

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Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.

Nat Commun 2019 Aug 23;10(1):3834. Epub 2019 Aug 23.

Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41467-019-11874-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707297PMC
August 2019

Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans.

BMC Genet 2019 Jul 2;20(1):52. Epub 2019 Jul 2.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1186/s12863-019-0758-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604157PMC
July 2019

Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy.

Circ Genom Precis Med 2019 Jun 6;12(6):e002390. Epub 2019 May 6.

Department of Genetics and Genomic Sciences (I.F., B.R., L.A., S.K., J.T.D., C.G., J.L.M.B., I.P.), Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1161/CIRCGEN.118.002390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601350PMC
June 2019

Critical period plasticity-related transcriptional aberrations in schizophrenia and bipolar disorder.

Schizophr Res 2019 May 12;207:12-21. Epub 2018 Nov 12.

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964183062
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http://dx.doi.org/10.1016/j.schres.2018.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591017PMC
May 2019

PI3K inhibitors protect against glucocorticoid-induced skin atrophy.

EBioMedicine 2019 Mar 5;41:526-537. Epub 2019 Feb 5.

Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.01.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441871PMC
March 2019

Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.

Neuron 2018 07 21;99(1):64-82.e7. Epub 2018 Jun 21.

Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ 85287-5001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551233PMC
July 2018

Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain.

Neuroscience 2018 02 28;371:455-468. Epub 2017 Dec 28.

Raymond G. Perelman Center for Cellular & Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03064522173092
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http://dx.doi.org/10.1016/j.neuroscience.2017.12.033DOI Listing
February 2018

Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions.

PLoS Genet 2018 01 24;14(1):e1007169. Epub 2018 Jan 24.

Department of Neurology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798844PMC
January 2018

Systems Medicine Approaches to Improving Understanding, Treatment, and Clinical Management of Neuroendocrine Prostate Cancer.

Curr Pharm Des 2016 ;22(34):5234-5248

Department of Genetics and Genomic Sciences Mount Sinai Health System, New York, NY, USA.

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http://dx.doi.org/10.2174/1381612822666160513145924DOI Listing
December 2017

Necroptosis activation in Alzheimer's disease.

Nat Neurosci 2017 Sep 24;20(9):1236-1246. Epub 2017 Jul 24.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1038/nn.4608DOI Listing
September 2017

Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine.

JACC Basic Transl Sci 2017 Jun 26;2(3):311-327. Epub 2017 Jun 26.

Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York.

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http://dx.doi.org/10.1016/j.jacbts.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034501PMC
June 2017

Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease.

PLoS Genet 2016 07 8;12(7):e1006137. Epub 2016 Jul 8.

Icahn Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938493PMC
July 2016

In silico methods for drug repurposing and pharmacology.

Wiley Interdiscip Rev Syst Biol Med 2016 05 15;8(3):186-210. Epub 2016 Apr 15.

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, New York, NY, USA.

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http://dx.doi.org/10.1002/wsbm.1337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845762PMC
May 2016

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach.

Lancet Psychiatry 2016 Apr 23;3(4):350-7. Epub 2016 Feb 23.

Division of Psychiatric Genomics, Department of Psychiatry, New York, NY, USA; Institute for Genomics and Multiscale Biology, New York, NY, USA; Department of Genetics and Genomic Sciences, New York, NY, USA; Friedman Brain Institute, New York, NY, USA.

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http://dx.doi.org/10.1016/S2215-0366(15)00553-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982509PMC
April 2016

Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease.

Cell Syst 2016 03 3;2(3):196-208. Epub 2016 Mar 3.

Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Physiology, Institute of Biomedicine and Translation Medicine, University of Tartu, 51014 Tartu, Estonia; Clinical Gene Networks AB, 114 44 Stockholm, Sweden; Department of Genetics & Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Cardiovascular Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855300PMC
March 2016

Computational and experimental advances in drug repositioning for accelerated therapeutic stratification.

Curr Top Med Chem 2015 ;15(1):5-20

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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https://www.researchgate.net/profile/Shameer_Khader/publicat
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http://dx.doi.org/10.2174/1568026615666150112103510DOI Listing
September 2015

Integrative network modeling approaches to personalized cancer medicine.

Per Med 2015 Jun;12(3):245-257

Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute for Genomics & Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.2217/pme.14.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806849PMC
June 2015

Automated detection of off-label drug use.

PLoS One 2014 19;9(2):e89324. Epub 2014 Feb 19.

Center for Biomedical Informatics Research, Stanford University, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089324PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929699PMC
October 2014

Translational Bioinformatics Approaches to Drug Development.

Adv Wound Care (New Rochelle) 2013 Nov;2(9):470-489

Center for Biomedical Informatics, Icahn School of Medicine at Mount Sinai , New York, New York. ; Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai , New York, New York. ; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai , New York, New York.

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http://dx.doi.org/10.1089/wound.2012.0422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817001PMC
November 2013