Ben Loos

Ben Loos

UNVERIFIED PROFILE

Are you Ben Loos?   Register this Author

Register author
Ben Loos

Ben Loos

Publications by authors named "Ben Loos"

Are you Ben Loos?   Register this Author

35Publications

401Reads

27Profile Views

Measuring autophagosome flux.

Autophagy 2018 20;14(6):1060-1071. Epub 2018 Jul 20.

c Department of Physiological Sciences, Faculty of Natural Sciences , University of Stellenbosch , Stellenbosch , South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2018.1469590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103398PMC
October 2019

The good, the bad and the autophagosome: exploring unanswered questions of autophagy-dependent cell death.

Cell Death Differ 2019 Mar 18;26(4):640-652. Epub 2019 Jan 18.

Department of Physiological Sciences, University of Stellenbosch, Stellenbosch, 7600, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-018-0267-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460391PMC
March 2019

Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation.

Sci Rep 2019 Mar 18;9(1):4782. Epub 2019 Mar 18.

Division of Medical Physiology, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-41108-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423017PMC
March 2019

Wild-type and mutant (G2019S) leucine-rich repeat kinase 2 (LRRK2) associate with subunits of the translocase of outer mitochondrial membrane (TOM) complex.

Exp Cell Res 2019 Feb 28;375(2):72-79. Epub 2018 Dec 28.

Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2018.12.022DOI Listing
February 2019

Improved region of interest selection and colocalization analysis in three-dimensional fluorescence microscopy samples using virtual reality.

PLoS One 2018 29;13(8):e0201965. Epub 2018 Aug 29.

Department of Electrical and Electronic Engineering, Stellenbosch University, Stellenbosch, Western Cape, South Africa.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201965PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114514PMC
January 2019

The palladacycle complex AJ-5 induces apoptotic cell death while reducing autophagic flux in rhabdomyosarcoma cells.

Cell Death Discov 2019 28;5:60. Epub 2019 Jan 28.

1Division of Cell Biology, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41420-019-0139-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349869PMC
January 2019

New Insights Into Autophagy Dysfunction Related to Amyloid Beta Toxicity and Neuropathology in Alzheimer's Disease.

Int Rev Cell Mol Biol 2018 6;336:321-361. Epub 2017 Sep 6.

Faculty of Science, University of Stellenbosch, Stellenbosch, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.ircmb.2017.07.002DOI Listing
December 2018

Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?

Toxicol Appl Pharmacol 2018 11 30;358:86-101. Epub 2018 Jun 30.

Department of Physiological Sciences, Stellenbosch University, Stellenbosch 7600, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2018.06.031DOI Listing
November 2018

The Precision Control of Autophagic Flux and Vesicle Dynamics-A Micropattern Approach.

Cells 2018 Aug 3;7(8). Epub 2018 Aug 3.

Department of Physiological Sciences, Stellenbosch University, Stellenbosch 7602, South Africa.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2073-4409/7/8/94
Publisher Site
http://dx.doi.org/10.3390/cells7080094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116198PMC
August 2018

Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics.

Sci Rep 2018 07 9;8(1):10348. Epub 2018 Jul 9.

Department of Physiological Sciences, Faculty of Science, University of Stellenbosch, Stellenbosch, 7600, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-28590-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037778PMC
July 2018

Nutrient excess and autophagic deficiency: explaining metabolic diseases in obesity.

Metabolism 2018 05 28;82:14-21. Epub 2017 Dec 28.

Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.metabol.2017.12.007DOI Listing
May 2018

Autophagy is essential for the maintenance of amino acids and ATP levels during acute amino acid starvation in MDAMB231 cells.

Cell Biochem Funct 2018 Mar 5;36(2):65-79. Epub 2018 Feb 5.

Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Stellenbosch, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbf.3318DOI Listing
March 2018

Doxorubicin resistance in breast cancer: A novel role for the human protein AHNAK.

Biochem Pharmacol 2018 02 5;148:174-183. Epub 2018 Jan 5.

Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Stellenbosch 7600, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2018.01.012DOI Listing
February 2018

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization.

Biochem Pharmacol 2018 01 2;147:170-182. Epub 2017 Dec 2.

Department of Physiological Sciences, Faculty of Science, University of Stellenbosch, Stellenbosch 7600, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2017.11.021DOI Listing
January 2018

Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging.

Prog Neurobiol 2017 Sep 11;156:90-106. Epub 2017 May 11.

School of Biological Sciences, Nanyang Technological University, SBS-03n-05,60 Nanyang Drive, Singapore 637551, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pneurobio.2017.05.001DOI Listing
September 2017

Autophagic flux control in neurodegeneration: Progress and precision targeting-Where do we stand?

Prog Neurobiol 2017 06 3;153:64-85. Epub 2017 Apr 3.

Department of Physiological Sciences, Faculty of Natural Sciences, University of Stellenbosch, Stellenbosch 7600, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pneurobio.2017.03.006DOI Listing
June 2017

Curcumin Rescues a PINK1 Knock Down SH-SY5Y Cellular Model of Parkinson's Disease from Mitochondrial Dysfunction and Cell Death.

Mol Neurobiol 2017 05 22;54(4):2752-2762. Epub 2016 Mar 22.

Division of Molecular Biology & Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-016-9843-0DOI Listing
May 2017

Virtual reality assisted microscopy data visualization and colocalization analysis.

BMC Bioinformatics 2017 Feb 15;18(Suppl 2):64. Epub 2017 Feb 15.

Stellenbosch University, Stellenbosch, 7600, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-016-1446-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333173PMC
February 2017

Filamin C: a novel component of the KCNE2 interactome during hypoxia.

Cardiovasc J Afr 2016 Jan-Feb;27(1):4-11

DST/NRF Centre of Excellence in Biomedical Tuberculosis Research, SA MRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5830/CVJA-2015-049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816932PMC
December 2016

Autophagy--A free meal in sickness-associated anorexia.

Autophagy 2016 ;12(4):727-34

b Department of Physiological Sciences , Faculty of Natural Sciences, Stellenbosch University , Stellenbosch , South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2016.1147672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836003PMC
December 2016

Autophagy and the invisible line between life and death.

Eur J Cell Biol 2016 Dec 26;95(12):598-610. Epub 2016 Oct 26.

Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Cape Town, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejcb.2016.10.005DOI Listing
December 2016

Melatonin: a protective role against doxorubicin-induced cardiotoxicity.

Future Oncol 2015 ;11(14):2003-6

Department of Physiological Sciences, Stellenbosch University, Stellenbosch, 7600, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon.15.48DOI Listing
May 2016

Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson's Disease Patients.

Parkinsons Dis 2016 8;2016:1819209. Epub 2016 Mar 8.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/1819209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807059PMC
April 2016

Defining and measuring autophagosome flux—concept and reality.

Autophagy 2014 ;10(11):2087-96

a Department of Physiological Sciences, Faculty of Science ; University of Stellenbosch ; Stellenbosch , South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/15548627.2014.973338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502790PMC
September 2015

Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1.

Eur J Neurosci 2015 May 11;41(9):1113-25. Epub 2015 Mar 11.

Division of Molecular Biology & Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 19063, Cape Town, 7505, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ejn.12872DOI Listing
May 2015

Ascribing novel functions to the sarcomeric protein, myosin binding protein H (MyBPH) in cardiac sarcomere contraction.

Exp Cell Res 2015 Feb 18;331(2):338-51. Epub 2014 Nov 18.

DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, MRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 19063, Francie van Zijl Drive, Tygerberg 7505, South Africa. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00144827140049
Publisher Site
http://dx.doi.org/10.1016/j.yexcr.2014.11.006DOI Listing
February 2015

Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin.

J Pineal Res 2014 Nov 18;57(4):367-80. Epub 2014 Oct 18.

Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jpi.12176DOI Listing
November 2014

Neurodegenerative disorders: dysregulation of a carefully maintained balance?

Exp Gerontol 2014 Oct 9;58:279-91. Epub 2014 Sep 9.

Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Cape Town, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2014.09.003DOI Listing
October 2014

Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutations.

Biochem Biophys Res Commun 2014 May 8;447(2):334-40. Epub 2014 Apr 8.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2014.03.151DOI Listing
May 2014

The variability of autophagy and cell death susceptibility: Unanswered questions.

Autophagy 2013 Sep 10;9(9):1270-85. Epub 2013 Jul 10.

Department of Physiological Sciences; Faculty of Natural Sciences; University of Stellenbosch; Stellenbosch, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/auto.25560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026026PMC
September 2013

Lactobacillus equigenerosi strain Le1 invades equine epithelial cells.

Appl Environ Microbiol 2012 Jun 13;78(12):4248-55. Epub 2012 Apr 13.

Department of Microbiology, University of Stellenbosch, Stellenbosch, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AEM.00552-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370564PMC
June 2012

Use of a profluorophore for visualization of the rupture of capsules in self-healing coatings.

Macromol Rapid Commun 2010 Apr 29;31(7):625-8. Epub 2009 Dec 29.

Department of Chemistry and Polymer Science, Stellenbosch University Private Bag X1, Matieland 7602, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/marc.200900728DOI Listing
April 2010