Publications by authors named "Ben Kinnersley"

43Publications

Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study.

Br J Cancer 2020 Oct 6. Epub 2020 Oct 6.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://dx.doi.org/10.1038/s41416-020-01083-1DOI Listing
October 2020

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.

Nat Commun 2020 07 3;11(1):3353. Epub 2020 Jul 3.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.

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http://dx.doi.org/10.1038/s41467-020-16483-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335068PMC
July 2020

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.

Authors:
Amand F Schmidt Michael V Holmes David Preiss Daniel I Swerdlow Spiros Denaxas Ghazaleh Fatemifar Rupert Faraway Chris Finan Dennis Valentine Zammy Fairhurst-Hunter Fernando Pires Hartwig Bernardo Lessa Horta Elina Hypponen Christine Power Max Moldovan Erik van Iperen Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Christina M Lill Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert A Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Tine Jess Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty Kirchner H Lester Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Rodney Scott Peter Schofield Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen D O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Tom Meade Ingrid E Christophersen Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Ronan Roussel Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Jemma C Hopewell Sudha Seshadri Caroline Dale Rui Providencia E Costa Paul M Ridker Daniel I Chasman Alex P Reiner Marylyn D Ritchie Leslie A Lange Alex J Cornish Sara E Dobbins Kari Hemminki Ben Kinnersley Marc Sanson Karim Labreche Matthias Simon Melissa Bondy Philip Law Helen Speedy James Allan Ni Li Molly Went Niels Weinhold Gareth Morgan Pieter Sonneveld Björn Nilsson Hartmut Goldschmidt Amit Sud Andreas Engert Markus Hansson Harry Hemingway Folkert W Asselbergs Riyaz S Patel Brendan J Keating Naveed Sattar Richard Houlston Juan P Casas Aroon D Hingorani

BMC Cardiovasc Disord 2019 10 29;19(1):240. Epub 2019 Oct 29.

Institute of Cardiovascular Science, University College London, 222 Euston Road, London, NW1 2DA, UK.

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http://dx.doi.org/10.1186/s12872-019-1187-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820948PMC
October 2019

Leveraging Human Genetics to Guide Cancer Drug Development.

JCO Clin Cancer Inform 2018 12;2:1-11

All authors: The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1200/CCI.18.00077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874034PMC
December 2018

Capture Hi-C Library Generation and Analysis to Detect Chromatin Interactions.

Curr Protoc Hum Genet 2018 Jul 6:e63. Epub 2018 Jul 6.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1002/cphg.63DOI Listing
July 2018

Genome-Wide Association Studies in Glioma.

Cancer Epidemiol Biomarkers Prev 2018 04 30;27(4):418-428. Epub 2018 Jan 30.

Department of Medicine, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-1080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931394PMC
April 2018

Genome-wide association studies of cancer: current insights and future perspectives.

Nat Rev Cancer 2017 11 13;17(11):692-704. Epub 2017 Oct 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research.

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http://dx.doi.org/10.1038/nrc.2017.82DOI Listing
November 2017

Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

Nat Genet 2017 03;49(4):651

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http://dx.doi.org/10.1038/ng0417-651aDOI Listing
March 2017

Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.

Gastroenterology 2017 01 3;152(1):75-77.e4. Epub 2016 Oct 3.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; Division of Pathology, The Institute of Cancer Research, London, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.09.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860724PMC
January 2017

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

Authors:
Timothy H T Cheng Deborah Thompson Jodie Painter Tracy O'Mara Maggie Gorman Lynn Martin Claire Palles Angela Jones Daniel D Buchanan Aung Ko Win John Hopper Mark Jenkins Noralane M Lindor Polly A Newcomb Steve Gallinger David Conti Fred Schumacher Graham Casey Graham G Giles Paul Pharoah Julian Peto Angela Cox Anthony Swerdlow Fergus Couch Julie M Cunningham Ellen L Goode Stacey J Winham Diether Lambrechts Peter Fasching Barbara Burwinkel Hermann Brenner Hiltrud Brauch Jenny Chang-Claude Helga B Salvesen Vessela Kristensen Hatef Darabi Jingmei Li Tao Liu Annika Lindblom Per Hall Magdalena Echeverry de Polanco Monica Sans Angel Carracedo Sergi Castellvi-Bel Augusto Rojas-Martinez Samuel Aguiar Jnr Manuel R Teixeira Alison M Dunning Joe Dennis Geoffrey Otton Tony Proietto Elizabeth Holliday John Attia Katie Ashton Rodney J Scott Mark McEvoy Sean C Dowdy Brooke L Fridley Henrica M J Werner Jone Trovik Tormund S Njolstad Emma Tham Miriam Mints Ingo Runnebaum Peter Hillemanns Thilo Dörk Frederic Amant Stefanie Schrauwen Alexander Hein Matthias W Beckmann Arif Ekici Kamila Czene Alfons Meindl Manjeet K Bolla Kyriaki Michailidou Jonathan P Tyrer Qin Wang Shahana Ahmed Catherine S Healey Mitul Shah Daniela Annibali Jeroen Depreeuw Nada A Al-Tassan Rebecca Harris Brian F Meyer Nicola Whiffin Fay J Hosking Ben Kinnersley Susan M Farrington Maria Timofeeva Albert Tenesa Harry Campbell Robert W Haile Shirley Hodgson Luis Carvajal-Carmona Jeremy P Cheadle Douglas Easton Malcolm Dunlop Richard Houlston Amanda Spurdle Ian Tomlinson

Sci Rep 2015 12 1;5:17369. Epub 2015 Dec 1.

Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/srep17369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664893PMC
December 2015

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

Nat Genet 2014 Jul 1;46(7):736-41. Epub 2014 Jun 1.

1] Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA. [2] [3].

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http://dx.doi.org/10.1038/ng.3002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074058PMC
July 2014

Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.

J Natl Cancer Inst 2014 Apr 26;106(5). Epub 2014 Apr 26.

Affiliations of authors: Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK (BK, RSH); Department of Medicine I, University Hospital Dresden, Dresden, Germany (SB); Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain (SCB); Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council (MRC) Human Genetics Unit, Edinburgh, UK (MGD, SMF); German Cancer Research Center, Heidelberg, Germany (AF, KH); Department of Internal Medicine I, Hospital Schleswig-Holstein, Kiel, Germany (JH); Leeds Cancer Research UK Centre, Section of Epidemiology and Biostatistics, Leeds Institute of Cancer Studies and Pathology, St James's University Hospital, Leeds, UK (EN, DTB); Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK (CP, IT); Department of Genetics, Portugese Oncology Institute, Porto, Portugal (MP, MRT); Galician Public Foundation of Genomic Medicine, Centro de Investigación Biomédica en Rad de Enfermedades Rares, Genomics Medicine Group, Hospital Clínico, Santiago de Compostela, University of Santiago de Compostela, Galicia, Spain (CRP); Department of General and Thoraci Surgery, University Hospital Schleswig-Holstein, Kiel, Germany (CS); University of Gronigen, University Medical Centre Gronigen, Department of Genetics, Gronigen, The Netherlands (HW, RMWH); Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands (RMWH); Leiden Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands (TW).

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http://dx.doi.org/10.1093/jnci/dju086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677263PMC
April 2014