Ben A Bahr

Ben A Bahr

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Ben A Bahr

Ben A Bahr

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Early Synaptic Alterations and Selective Adhesion Signaling in Hippocampal Dendritic Zones Following Organophosphate Exposure.

Sci Rep 2019 Apr 25;9(1):6532. Epub 2019 Apr 25.

Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, North Carolina, USA.

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http://dx.doi.org/10.1038/s41598-019-42934-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484076PMC
April 2019

Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases.

Curr Opin Neurobiol 2018 02 10;48:52-58. Epub 2017 Oct 10.

Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.conb.2017.09.005DOI Listing
February 2018

Aβ42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways.

PLoS One 2017 10;12(8):e0182895. Epub 2017 Aug 10.

Biotechnology Research and Training Center, William C. Friday Laboratory, University of North Carolina-Pembroke, Pembroke, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182895PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552263PMC
October 2017

Paraoxon: An Anticholinesterase That Triggers an Excitotoxic Cascade of Oxidative Stress, Adhesion Responses, and Synaptic Compromise.

Eur Sci J 2017 Oct;13:29-37

Biotechnology Research and Training Center, William C. Friday Laboratory, University of North Carolina - Pembroke, Pembroke, North Carolina, USA.

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http://dx.doi.org/10.19044/esj.2017.c1p4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966299PMC
October 2017

Inhibitor of Endocannabinoid Deactivation Protects Against In Vitro and In Vivo Neurotoxic Effects of Paraoxon.

J Mol Neurosci 2017 Sep 12;63(1):115-122. Epub 2017 Aug 12.

Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC, 28372-1510, USA.

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http://dx.doi.org/10.1007/s12031-017-0963-4DOI Listing
September 2017

Military blast-induced synaptic changes with distinct vulnerability may explain behavioral alterations in the absence of obvious brain damage.

J Nat Sci 2017 Jul;3(7)

William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina - Pembroke, Pembroke, North Carolina, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562167PMC
July 2017

Blast waves from detonated military explosive reduce GluR1 and synaptophysin levels in hippocampal slice cultures.

Exp Neurol 2016 Dec 5;286:107-115. Epub 2016 Oct 5.

Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2016.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767515PMC
December 2016

Abnormal response of distal Schwann cells to denervation in a mouse model of motor neuron disease.

Exp Neurol 2016 Apr 4;278:116-26. Epub 2016 Feb 4.

Department of Physiology, Emory University, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2016.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788963PMC
April 2016

A single pathway targets several health challenges of the elderly.

Authors:
Ben A Bahr

Rejuvenation Res 2014 Aug;17(4):382-4

Biotechnology Research and Training Center, William C. Friday Laboratory, University of North Carolina-Pembroke , Pembroke, North Carolina.

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http://dx.doi.org/10.1089/rej.2014.1585DOI Listing
August 2014

Slice Culture Method for Studying Migration of Neuronal Progenitor Cells Derived from Human Embryonic Stem Cells (hESC).

Curr Protoc Stem Cell Biol 2014 May 16;29:1H.7.1-14. Epub 2014 May 16.

Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut.

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http://dx.doi.org/10.1002/9780470151808.sc01h07s29DOI Listing
May 2014

Nonpeptidic lysosomal modulators derived from z-phe-ala-diazomethylketone for treating protein accumulation diseases.

ACS Med Chem Lett 2012 Nov 9;3(11):920-4. Epub 2012 Sep 9.

Department of Pharmaceutical Sciences, University of Connecticut , Storrs, Connecticut 06269, United States ; Synaptic Dynamics Inc. , Farmington, Connecticut 06032, United States.

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http://dx.doi.org/10.1021/ml300197hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025860PMC
November 2012

Positive lysosomal modulation as a unique strategy to treat age-related protein accumulation diseases.

Rejuvenation Res 2012 Apr;15(2):189-97

William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina Pembroke, Pembroke, North Carolina 28372-1510, USA.

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http://dx.doi.org/10.1089/rej.2011.1282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332372PMC
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404883PMC
http://dx.doi.org/10.4161/auto.19496DOI Listing
April 2012

Z-Phe-Ala-diazomethylketone (PADK) disrupts and remodels early oligomer states of the Alzheimer disease Aβ42 protein.

J Biol Chem 2012 Feb 17;287(9):6084-8. Epub 2012 Jan 17.

Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106-9510, USA.

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February 2012

Cleavage of the vesicular glutamate transporters under excitotoxic conditions.

Neurobiol Dis 2011 Dec 26;44(3):292-303. Epub 2011 Jul 26.

Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.nbd.2011.07.010DOI Listing
December 2011

Submicromolar Aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner.

Biochim Biophys Acta 2011 Dec 25;1812(12):1664-74. Epub 2011 Sep 25.

University of North Carolina, Pembroke, NC, USA.

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http://dx.doi.org/10.1016/j.bbadis.2011.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226336PMC
December 2011

A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity.

J Mol Neurosci 2011 Mar 11;43(3):493-502. Epub 2010 Nov 11.

Biotechnology Research and Training Center, University of North Carolina Pembroke, 115 Livermore Drive, Pembroke, NC 28372-1510, USA.

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http://dx.doi.org/10.1007/s12031-010-9472-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124033PMC
March 2011

Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia.

Brain Behav Immun 2010 Jul 24;24(5):822-30. Epub 2009 Sep 24.

Center for Brain Repair and Rehabilitation, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.bbi.2009.09.013DOI Listing
July 2010

Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality.

Life Sci 2010 Apr 13;86(15-16):615-23. Epub 2009 Jun 13.

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, Connecticut, USA.

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http://dx.doi.org/10.1016/j.lfs.2009.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848893PMC
April 2010

Lysosomal modulatory drugs for a broad strategy against protein accumulation disorders.

Authors:
Ben A Bahr

Curr Alzheimer Res 2009 Oct;6(5):438-45

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, USA.

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October 2009

Human neural precursor cells continue to proliferate and exhibit low cell death after transplantation to the injured rat spinal cord.

Brain Res 2009 Jun 17;1278:15-26. Epub 2009 Apr 17.

Division of Neurodegeneration, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Geriatric Clinic Res. Lab., Novum level 5, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.brainres.2009.04.012DOI Listing
June 2009

Ampakine CX516 ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation.

Exp Neurol 2008 Nov 18;214(1):55-61. Epub 2008 Jul 18.

Department of Pharmacal Sciences, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA.

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http://dx.doi.org/10.1016/j.expneurol.2008.07.010DOI Listing
November 2008

Gephyrin interacts with the glutamate receptor interacting protein 1 isoforms at GABAergic synapses.

J Neurochem 2008 Jun;105(6):2300-14

Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269-3156, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05311.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891215PMC
June 2008

Protein kinase C is a common component of CGRP receptor desensitization induced by distinct agonists.

Eur J Pharmacol 2008 Jun 13;587(1-3):8-15. Epub 2008 Mar 13.

Bristol-Myers Squibb Co., 5 Research Parkway, Wallingford, CT 06492, USA.

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June 2008

Calpain activation is involved in early caspase-independent neurodegeneration in the hippocampus following status epilepticus.

J Neurochem 2008 May 10;105(3):666-76. Epub 2007 Dec 10.

Center for Neuroscience and Cell Biology, Department of Zoology, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1111/j.1471-4159.2007.05181.xDOI Listing
May 2008

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.

Authors:
Daniel J Klionsky Hagai Abeliovich Patrizia Agostinis Devendra K Agrawal Gjumrakch Aliev David S Askew Misuzu Baba Eric H Baehrecke Ben A Bahr Andrea Ballabio Bruce A Bamber Diane C Bassham Ettore Bergamini Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Dale E Bredesen Jeffrey L Brodsky John H Brumell Ulf T Brunk Wilfried Bursch Nadine Camougrand Eduardo Cebollero Francesco Cecconi Yingyu Chen Lih-Shen Chin Augustine Choi Charleen T Chu Jongkyeong Chung Peter G H Clarke Robert S B Clark Steven G Clarke Corinne Clavé John L Cleveland Patrice Codogno María I Colombo Ana Coto-Montes James M Cregg Ana Maria Cuervo Jayanta Debnath Francesca Demarchi Patrick B Dennis Phillip A Dennis Vojo Deretic Rodney J Devenish Federica Di Sano J Fred Dice Marian Difiglia Savithramma Dinesh-Kumar Clark W Distelhorst Mojgan Djavaheri-Mergny Frank C Dorsey Wulf Dröge Michel Dron William A Dunn Michael Duszenko N Tony Eissa Zvulun Elazar Audrey Esclatine Eeva-Liisa Eskelinen László Fésüs Kim D Finley José M Fuentes Juan Fueyo Kozo Fujisaki Brigitte Galliot Fen-Biao Gao David A Gewirtz Spencer B Gibson Antje Gohla Alfred L Goldberg Ramon Gonzalez Cristina González-Estévez Sharon Gorski Roberta A Gottlieb Dieter Häussinger You-Wen He Kim Heidenreich Joseph A Hill Maria Høyer-Hansen Xun Hu Wei-Pang Huang Akiko Iwasaki Marja Jäättelä William T Jackson Xuejun Jiang Shengkan Jin Terje Johansen Jae U Jung Motoni Kadowaki Chanhee Kang Ameeta Kelekar David H Kessel Jan A K W Kiel Hong Pyo Kim Adi Kimchi Timothy J Kinsella Kirill Kiselyov Katsuhiko Kitamoto Erwin Knecht Masaaki Komatsu Eiki Kominami Seiji Kondo Attila L Kovács Guido Kroemer Chia-Yi Kuan Rakesh Kumar Mondira Kundu Jacques Landry Marianne Laporte Weidong Le Huan-Yao Lei Michael J Lenardo Beth Levine Andrew Lieberman Kah-Leong Lim Fu-Cheng Lin Willisa Liou Leroy F Liu Gabriel Lopez-Berestein Carlos López-Otín Bo Lu Kay F Macleod Walter Malorni Wim Martinet Ken Matsuoka Josef Mautner Alfred J Meijer Alicia Meléndez Paul Michels Giovanni Miotto Wilhelm P Mistiaen Noboru Mizushima Baharia Mograbi Iryna Monastyrska Michael N Moore Paula I Moreira Yuji Moriyasu Tomasz Motyl Christian Münz Leon O Murphy Naweed I Naqvi Thomas P Neufeld Ichizo Nishino Ralph A Nixon Takeshi Noda Bernd Nürnberg Michinaga Ogawa Nancy L Oleinick Laura J Olsen Bulent Ozpolat Shoshana Paglin Glen E Palmer Issidora Papassideri Miles Parkes David H Perlmutter George Perry Mauro Piacentini Ronit Pinkas-Kramarski Mark Prescott Tassula Proikas-Cezanne Nina Raben Abdelhaq Rami Fulvio Reggiori Bärbel Rohrer David C Rubinsztein Kevin M Ryan Junichi Sadoshima Hiroshi Sakagami Yasuyoshi Sakai Marco Sandri Chihiro Sasakawa Miklós Sass Claudio Schneider Per O Seglen Oleksandr Seleverstov Jeffrey Settleman John J Shacka Irving M Shapiro Andrei Sibirny Elaine C M Silva-Zacarin Hans-Uwe Simon Cristiano Simone Anne Simonsen Mark A Smith Katharina Spanel-Borowski Vickram Srinivas Meredith Steeves Harald Stenmark Per E Stromhaug Carlos S Subauste Seiichiro Sugimoto David Sulzer Toshihiko Suzuki Michele S Swanson Ira Tabas Fumihiko Takeshita Nicholas J Talbot Zsolt Tallóczy Keiji Tanaka Kozo Tanaka Isei Tanida Graham S Taylor J Paul Taylor Alexei Terman Gianluca Tettamanti Craig B Thompson Michael Thumm Aviva M Tolkovsky Sharon A Tooze Ray Truant Lesya V Tumanovska Yasuo Uchiyama Takashi Ueno Néstor L Uzcátegui Ida van der Klei Eva C Vaquero Tibor Vellai Michael W Vogel Hong-Gang Wang Paul Webster John W Wiley Zhijun Xi Gutian Xiao Joachim Yahalom Jin-Ming Yang George Yap Xiao-Ming Yin Tamotsu Yoshimori Li Yu Zhenyu Yue Michisuke Yuzaki Olga Zabirnyk Xiaoxiang Zheng Xiongwei Zhu Russell L Deter

Autophagy 2008 Feb 21;4(2):151-75. Epub 2007 Nov 21.

Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109-2216, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654259PMC
http://dx.doi.org/10.4161/auto.5338DOI Listing
February 2008

Gephyrin alterations due to protein accumulation stress are reduced by the lysosomal modulator Z-Phe-Ala-diazomethylketone.

J Mol Neurosci 2008 Feb 18;34(2):131-9. Epub 2007 Sep 18.

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1007/s12031-007-9009-7DOI Listing
February 2008

Desensitization and re-sensitization of CGRP receptor function in human neuroblastoma SK-N-MC cells.

Eur J Pharmacol 2007 Dec 17;577(1-3):7-16. Epub 2007 Aug 17.

Bristol-Myers Squibb Co., 5 Research Parkway, Wallingford, CT 06492, United States.

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http://dx.doi.org/10.1016/j.ejphar.2007.08.014DOI Listing
December 2007

Death effector activation in the subventricular zone subsequent to perinatal hypoxia/ischemia.

J Neurochem 2007 Nov 17;103(3):1121-31. Epub 2007 Aug 17.

Molecular Medicine Graduate Program, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04820.xDOI Listing
November 2007

Memory impairments and hippocampal modifications in adult rats with neonatal isolation stress experience.

Neurobiol Learn Mem 2007 Sep 31;88(2):167-76. Epub 2007 May 31.

Menninger Department of Psychiatry, Baylor College of Medicine and the Michael E. DeBakey VA Medical Center, Research Service Line (151), 2002 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.nlm.2007.03.011DOI Listing
September 2007

Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage.

J Pharmacol Exp Ther 2007 Sep 1;322(3):1059-66. Epub 2007 Jun 1.

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269-3092, USA.

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http://dx.doi.org/10.1124/jpet.107.120147DOI Listing
September 2007

Early necrosis and apoptosis of Schwann cells transplanted into the injured rat spinal cord.

Eur J Neurosci 2007 Sep;26(6):1433-45

The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2007.05771.xDOI Listing
September 2007

Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS.

Anal Chem 2007 Aug 29;79(15):5582-93. Epub 2007 Jun 29.

Center for Drug Discovery, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1021/ac0624086DOI Listing
August 2007

Amyloid beta-peptide Abeta(1-42) but not Abeta(1-40) attenuates synaptic AMPA receptor function.

Synapse 2007 Jun;61(6):367-74

Department of Pharmacal Sciences, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA.

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http://dx.doi.org/10.1002/syn.20386DOI Listing
June 2007

Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers.

Eur J Pharmacol 2007 May 8;562(1-2):20-7. Epub 2007 Feb 8.

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, CT 06269-3092, USA.

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http://dx.doi.org/10.1016/j.ejphar.2007.01.053DOI Listing
May 2007

Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases.

Autophagy 2006 Jul-Sep;2(3):234-7. Epub 2006 Jul 22.

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, Connecticut 06269-3092, USA.

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http://dx.doi.org/10.4161/auto.2729DOI Listing
February 2007

Excitotoxic protection by polyanionic polysaccharide: evidence of a cell survival pathway involving AMPA receptor-MAPK Interactions.

J Neurosci Res 2007 Feb;85(2):294-302

Cognetix, Inc., Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1002/jnr.21117DOI Listing
February 2007

Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons.

Eur J Pharmacol 2007 Feb 22;557(2-3):106-14. Epub 2006 Nov 22.

Department of Physiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.

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http://dx.doi.org/10.1016/j.ejphar.2006.11.032DOI Listing
February 2007

3-Nitropropionic acid toxicity in hippocampus: protection through N-methyl-D-aspartate receptor antagonism.

Hippocampus 2006 ;16(10):834-42

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, USA.

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http://dx.doi.org/10.1002/hipo.20214DOI Listing
December 2006

Modulatory effects of dextran sulfate and fucoidan on binding and channel properties of AMPA receptors isolated from rat brain.

Synapse 2006 Nov;60(6):456-64

Department of Pharmacal Sciences, Harrison School of Pharmacy, Auburn University, Alabama 36849, USA.

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http://dx.doi.org/10.1002/syn.20319DOI Listing
November 2006

Cannabinoid drugs and enhancement of endocannabinoid responses: strategies for a wide array of disease states.

Curr Mol Med 2006 Sep;6(6):677-84

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269-3092, USA.

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September 2006

Oxidative stress and lysosomes: CNS-related consequences and implications for lysosomal enhancement strategies and induction of autophagy.

Antioxid Redox Signal 2006 Jan-Feb;8(1-2):185-96

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-3092, USA.

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http://dx.doi.org/10.1089/ars.2006.8.185DOI Listing
May 2006

Targeting the endocannabinoid system in treating brain disorders.

Expert Opin Investig Drugs 2006 Apr;15(4):351-65

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.

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http://dx.doi.org/10.1517/13543784.15.4.351DOI Listing
April 2006

Cellular responses to protein accumulation involve autophagy and lysosomal enzyme activation.

Rejuvenation Res 2005 ;8(4):227-37

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, 06269, USA.

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http://dx.doi.org/10.1089/rej.2005.8.227DOI Listing
January 2006

Dual modulation of endocannabinoid transport and fatty acid amide hydrolase protects against excitotoxicity.

J Neurosci 2005 Aug;25(34):7813-20

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2347-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725251PMC
August 2005

Single channel recordings from synaptosomal AMPA receptors.

Cell Biochem Biophys 2005 ;42(1):75-85

Department of Pharmacal Sciences, 401 Walker Building, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA.

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http://dx.doi.org/10.1385/CBB:42:1:075DOI Listing
June 2005

The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide.

J Neurochem 2005 Jun;93(5):1280-92

Institute of Molecular and Cell Biology (IMCB), Singapore.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03122.xDOI Listing
June 2005

Proteolysis of NR2B by calpain in the hippocampus of epileptic rats.

Neuroreport 2005 Mar;16(4):393-6

Center for Neuroscience and Cell Biology, Department of Zoology, Faculty of Medicine, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1097/00001756-200503150-00017DOI Listing
March 2005

Blocking cannabinoid activation of FAK and ERK1/2 compromises synaptic integrity in hippocampus.

Eur J Pharmacol 2005 Jan 7;508(1-3):47-56. Epub 2005 Jan 7.

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269-2092, USA.

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http://dx.doi.org/10.1016/j.ejphar.2004.12.009DOI Listing
January 2005

Early calpain-mediated proteolysis following AMPA receptor activation compromises neuronal survival in cultured hippocampal neurons.

J Neurochem 2004 Dec;91(6):1322-31

Center for Neuroscience and Cell Biology, Department of Zoology, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02811.xDOI Listing
December 2004

Biphasic NF-kappaB activation in the excitotoxic hippocampus.

Acta Neuropathol 2004 Sep 8;108(3):173-82. Epub 2004 May 8.

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, CT 06269-2092, USA.

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http://dx.doi.org/10.1007/s00401-004-0876-5DOI Listing
September 2004

Repeated contact with subtoxic soman leads to synaptic vulnerability in hippocampus.

J Neurosci Res 2004 Sep;77(5):739-46

Department of Pharmaceutical Sciences, Center for Drug Discovery, University of Connecticut, Storrs, Connecticut 06269, USA.

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http://dx.doi.org/10.1002/jnr.20209DOI Listing
September 2004

Sulfate- and size-dependent polysaccharide modulation of AMPA receptor properties.

J Neurosci Res 2004 Feb;75(3):408-16

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, USA.

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http://doi.wiley.com/10.1002/jnr.10871
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http://dx.doi.org/10.1002/jnr.10871DOI Listing
February 2004

Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival.

Neurobiol Dis 2003 Dec;14(3):513-23

Section of Restorative Neurology, Wallenberg Neuroscience Center, BMC A11, SE-221 84 Lund, Sweden.

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December 2003

Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease?

J Neuropathol Exp Neurol 2003 May;62(5):451-63

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Stors, Connecticut, USA.

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http://dx.doi.org/10.1093/jnen/62.5.451DOI Listing
May 2003

Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptors elicits neuroprotection after trimethyltin exposure in hippocampus.

Toxicol Appl Pharmacol 2002 Dec;185(2):111-8

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, Connecticut 06269-2092, USA.

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http://dx.doi.org/10.1006/taap.2002.9534DOI Listing
December 2002

The neuropathogenic contributions of lysosomal dysfunction.

J Neurochem 2002 Nov;83(3):481-9

Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269-2092, USA.

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http://dx.doi.org/10.1046/j.1471-4159.2002.01192.xDOI Listing
November 2002

Intracellular deposition, microtubule destabilization, and transport failure: an "early" pathogenic cascade leading to synaptic decline.

J Neuropathol Exp Neurol 2002 Jul;61(7):640-50

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs 06269-2092, USA.

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http://dx.doi.org/10.1093/jnen/61.7.640DOI Listing
July 2002

Survival signaling and selective neuroprotection through glutamatergic transmission.

Exp Neurol 2002 Mar;174(1):37-47

Department of Pharmaceutical Sciences and the Neurosciences Program, Center for Drug Discovery, University of Connecticut, Storrs, Connecticut, USA.

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http://dx.doi.org/10.1006/exnr.2001.7852DOI Listing
March 2002

Peptidyl alpha-keto amide inhibitor of calpain blocks excitotoxic damage without affecting signal transduction events.

J Neurosci Res 2002 Mar;67(6):787-94

Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, Connecticut 06269-2092, USA.

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http://dx.doi.org/10.1002/jnr.10163DOI Listing
March 2002