Publications by authors named "Beisi Xu"

41Publications

A predictive signature for oxaliplatin and 5-fluorouracil based chemotherapy in locally advanced gastric cancer.

Transl Oncol 2021 Jan 20;14(1):100901. Epub 2020 Oct 20.

Department of Surgical Oncology, Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address:

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January 2021

UTX/KDM6A suppresses AP-1 and a gliogenesis program during neural differentiation of human pluripotent stem cells.

Epigenetics Chromatin 2020 09 25;13(1):38. Epub 2020 Sep 25.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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September 2020

Ybx1 fine-tunes PRC2 activities to control embryonic brain development.

Nat Commun 2020 08 13;11(1):4060. Epub 2020 Aug 13.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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August 2020

An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.

Cancer Res 2020 04 16;80(7):1524-1537. Epub 2020 Jan 16.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.

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April 2020

Muscle-derived Dpp regulates feeding initiation via endocrine modulation of brain dopamine biosynthesis.

Genes Dev 2020 01 12;34(1-2):37-52. Epub 2019 Dec 12.

Division of Developmental Biology, Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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January 2020

Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease.

Cell Immunol 2019 12 25;346:103996. Epub 2019 Oct 25.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA. Electronic address:

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December 2019

Nucleome Dynamics during Retinal Development.

Neuron 2019 11 4;104(3):512-528.e11. Epub 2019 Sep 4.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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November 2019

Acute depletion of CTCF directly affects MYC regulation through loss of enhancer-promoter looping.

Nucleic Acids Res 2019 07;47(13):6699-6713

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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July 2019

Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1.

Nat Neurosci 2019 03 4;22(3):362-373. Epub 2019 Feb 4.

Department of Developmental Neurobiology and Division of Developmental Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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March 2019

The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number.

Dev Cell 2018 12 25;47(5):576-591.e8. Epub 2018 Oct 25.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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December 2018

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Cancer Cell 2018 09 23;34(3):411-426.e19. Epub 2018 Aug 23.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 323, Memphis, TN 38105-3678, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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September 2018

Mouse medulloblastoma driven by CRISPR activation of cellular Myc.

Sci Rep 2018 06 7;8(1):8733. Epub 2018 Jun 7.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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June 2018

Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures.

Cell Rep 2018 03;22(10):2601-2614

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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March 2018

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis.

Neuron 2017 May;94(3):550-568.e10

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA. Electronic address:

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May 2017

Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression.

Mol Immunol 2016 09 3;77:97-102. Epub 2016 Aug 3.

Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA. Electronic address:

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September 2016

Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.

Development 2015 Dec;142(23):4092-106

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA

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December 2015

The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling.

Genes Dev 2015 Dec 19;29(23):2475-89. Epub 2015 Nov 19.

Department of Developmental Neurobiology, Division of Developmental Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA;

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December 2015

Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.

Cell Stem Cell 2015 Jul;17(1):101-15

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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July 2015

Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells.

Genome Biol 2015 Jun 2;16:115. Epub 2015 Jun 2.

Department of Environmental Health Sciences, Laboratory of Human Environmental Epigenomes, Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe Street, Room E7816, Baltimore, MD, 21205, USA.

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June 2015

Epigenetic dysregulation by nickel through repressive chromatin domain disruption.

Proc Natl Acad Sci U S A 2014 Oct 22;111(40):14631-6. Epub 2014 Sep 22.

Department of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987;

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October 2014

A structural-based strategy for recognition of transcription factor binding sites.

PLoS One 2013 8;8(1):e52460. Epub 2013 Jan 8.

Laboratory of Molecular Modeling and Design, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian, Liaoning, China.

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August 2013

Fast and accurate computation schemes for evaluating vibrational entropy of proteins.

J Comput Chem 2011 Nov 27;32(15):3188-93. Epub 2011 Aug 27.

State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian, China.

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November 2011

Insight into mechanism of small molecule inhibitors of the MDM2-p53 interaction: molecular dynamics simulation and free energy analysis.

J Mol Graph Model 2011 Sep 13;30:46-53. Epub 2011 Jun 13.

Laboratory of Molecular Modeling and Design, State Kay Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Science, 116011 China.

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September 2011

An all-atom knowledge-based energy function for protein-DNA threading, docking decoy discrimination, and prediction of transcription-factor binding profiles.

Proteins 2009 Aug;76(3):718-30

Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, China.

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August 2009

Thermodynamic behaviors of polyampholytes at low temperatures.

J Chem Phys 2004 Oct;121(15):7494-500

Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.

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October 2004