Publications by authors named "Beisha Tang"

100Publications

Association of arsenic exposure and cognitive impairment: A population-based cross-sectional study in China.

Neurotoxicology 2020 Nov 26. Epub 2020 Nov 26.

National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China; Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2020.11.009DOI Listing
November 2020

Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.

Eur J Neurosci 2020 Nov 23. Epub 2020 Nov 23.

Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China.

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http://dx.doi.org/10.1111/ejn.15058DOI Listing
November 2020

Age is an important independent modifier of SCA3 phenotype severity.

Neurosci Lett 2020 Nov 19:135510. Epub 2020 Nov 19.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Diseases, Central South University, Changsha, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, China; Laboratory of Medical Genetics, Central South University, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2020.135510DOI Listing
November 2020

Author Correction: Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form.

Nat Commun 2020 Nov 19;11(1):5989. Epub 2020 Nov 19.

Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, 510632, Guangzhou, China.

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http://dx.doi.org/10.1038/s41467-020-19873-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677395PMC
November 2020

Rare variant analysis of essential tremor-associated genes in early-onset Parkinson's disease.

Ann Clin Transl Neurol 2020 Nov 13. Epub 2020 Nov 13.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.

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http://dx.doi.org/10.1002/acn3.51248DOI Listing
November 2020

Olfactory Dysfunction and Its Relationship With Clinical Features of Parkinson's Disease.

Front Neurol 2020 16;11:526615. Epub 2020 Oct 16.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fneur.2020.526615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596377PMC
October 2020

No relationship between SRY variants and risk of Parkinson's disease in Chinese population.

Neurobiol Aging 2020 Sep 16. Epub 2020 Sep 16.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China; Centre for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.09.013DOI Listing
September 2020

Preliminary Findings on Proline-Rich Protein 14 as a Diagnostic Biomarker for Parkinson's Disease.

Neuromolecular Med 2020 Oct 1. Epub 2020 Oct 1.

Department of Orthopedics, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, 410011, Hunan, China.

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http://dx.doi.org/10.1007/s12017-020-08617-zDOI Listing
October 2020

Identification of GGC repeat expansion in the gene in amyotrophic lateral sclerosis.

Neurology 2020 Sep 28. Epub 2020 Sep 28.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China

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http://dx.doi.org/10.1212/WNL.0000000000010945DOI Listing
September 2020

Homozygosity mapping and next generation sequencing for the genetic diagnosis of hereditary ataxia and spastic paraplegia in consanguineous families.

Parkinsonism Relat Disord 2020 Sep 14;80:65-72. Epub 2020 Sep 14.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Central South University, Changsha, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2020.09.013DOI Listing
September 2020

Association of rare variants in neurodegenerative genes with familial Alzheimer's disease.

Ann Clin Transl Neurol 2020 10 17;7(10):1985-1995. Epub 2020 Sep 17.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.1002/acn3.51197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545599PMC
October 2020

MR Imaging of SCA3/MJD.

Front Neurosci 2020 4;14:749. Epub 2020 Aug 4.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fnins.2020.00749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417615PMC
August 2020

Association of serum neurofilament light (sNfL) and disease severity in patients with spinocerebellar ataxia type 3.

Neurology 2020 Aug 14. Epub 2020 Aug 14.

From the Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, USA.Institute of Chemical Biology and Nanomedicine (ICBN), Hunan University, Changsha, Hunan, P. R. China.Health Management Center, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.Department of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.School of Computer Science and Engineering, Central South University, Changsha, Hunan, P. R. China.Department of Neurology, University of Bonn, Bonn, Germany.German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.Laboratory of Medical Genetics, Central South University, Changsha, Hunan, P. R. China.National Clinical Research Center for Geriatric Diseases, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, P. R. China.

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http://dx.doi.org/10.1212/WNL.0000000000010671DOI Listing
August 2020

No genetic evidence for the involvement of GGC repeat expansions of the NOTCH2NLC gene in Chinese patients with multiple system atrophy.

Neurobiol Aging 2020 Jul 15. Epub 2020 Jul 15.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China; Laboratory of Medical Genetics, Central South University, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.07.008DOI Listing
July 2020

Progress in -Associated Parkinson's Disease Animal Models.

Front Neurosci 2020 15;14:674. Epub 2020 Jul 15.

Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.3389/fnins.2020.00674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381130PMC
July 2020

Loss of Hap1 selectively promotes striatal degeneration in Huntington disease mice.

Proc Natl Acad Sci U S A 2020 08 3;117(33):20265-20273. Epub 2020 Aug 3.

Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, Guangzhou 510632, China

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http://dx.doi.org/10.1073/pnas.2002283117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443904PMC
August 2020

Rare, pathogenic variants in LRP10 are associated with amyotrophic lateral sclerosis in patients from mainland China.

Neurobiol Aging 2020 Jun 25. Epub 2020 Jun 25.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China; National Clinical Research Center for Geriatric Diseases, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, P. R. China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, P. R. China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.06.013DOI Listing
June 2020

Generation of an induced pluripotent stem cell line (GIBHi004-A) from a Parkinson's disease patient with mutant DJ-1/PARK7 (p.L10P).

Stem Cell Res 2020 07 27;46:101845. Epub 2020 May 27.

Laboratory of Integrative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou 510530, China; Guangzhou Medical University, Guangzhou 511436, China. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2020.101845DOI Listing
July 2020

PINK1 phosphorylates Drp1 to regulate mitophagy-independent mitochondrial dynamics.

EMBO Rep 2020 Aug 2;21(8):e48686. Epub 2020 Jun 2.

Key Laboratory of Molecular Precision Medicine of Hunan Province and Center for Medical Genetics, Institute of Molecular Precision Medicine, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.15252/embr.201948686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403662PMC
August 2020

Propagation of Pathological α-Synuclein from the Urogenital Tract to the Brain Initiates MSA-like Syndrome.

iScience 2020 Jun 15;23(6):101166. Epub 2020 May 15.

Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Institute of Parkinson and Movement Disorder, Zhengzhou University, Zhengzhou, Henan 450052, China. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.101166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260590PMC
June 2020

Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form.

Nat Commun 2020 05 22;11(1):2582. Epub 2020 May 22.

Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, 510632, Guangzhou, China.

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http://dx.doi.org/10.1038/s41467-020-16318-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244548PMC
May 2020

Genetic analysis of N6-methyladenosine modification genes in Parkinson's disease.

Neurobiol Aging 2020 09 8;93:143.e9-143.e13. Epub 2020 Apr 8.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders (Xiangya), Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.03.018DOI Listing
September 2020

Generation of induced pluripotent stem cell line (CSUXHi002-A) from a patient with spinocerebellar ataxia type 1.

Stem Cell Res 2020 05 21;45:101816. Epub 2020 Apr 21.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Diseases, Central South University, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, China; Xinjiang Medical University, Urumchi, Xinjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2020.101816DOI Listing
May 2020

Bruceine D elevates Nrf2 activation to restrain Parkinson's disease in mice through suppressing oxidative stress and inflammatory response.

Biochem Biophys Res Commun 2020 06 19;526(4):1013-1020. Epub 2020 Apr 19.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, 410078, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.03.097DOI Listing
June 2020

Corrigendum to "Profiling of mitochondrial genomes in SCA3/MJD patients from mainland China" [Gene 738 (2020) 144487].

Gene 2020 May 31;740:144607. Epub 2020 Mar 31.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Diseases, Central South University, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, China; Xinjiang Medical University, Urumchi, Xinjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2020.144607DOI Listing
May 2020

[Expert consensus on the management strategy of patients with hereditary ataxia during prevention and control of novel coronavirus pneumonia epidemic].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 Apr;37(4):359-366

Department of Neurology, Hunan Provincial Key Laboratory for Neurodegenerative Disorders, National Clinical Medical Research Center for Geriatric Diseases, Xiangya Hospital, Central South University, Changsha, Hunan 410083, China.

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2020.04.001DOI Listing
April 2020

Allele-specific genome targeting in the development of precision medicine.

Theranostics 2020 10;10(7):3118-3137. Epub 2020 Feb 10.

National Clinical Research Center for Geriatric Disorders, Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.

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http://dx.doi.org/10.7150/thno.43298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053192PMC
February 2020

Myeleterosis in an ALPS5 patient with primary immune dysregulation syndrome.

CNS Neurosci Ther 2020 07 17;26(7):773-775. Epub 2020 Mar 17.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.1111/cns.13301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298977PMC
July 2020

Corrigendum to "PRRT2 frameshift mutation reduces its mRNA stability resulting loss of function in paroxysmal kinesigenic dyskinesia".

Biochem Biophys Res Commun 2020 May 10;525(3):821. Epub 2020 Mar 10.

Department of Neurology & Key Laboratory of Hunan Province in Neurodegenerative Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.02.159DOI Listing
May 2020

Corrigendum: Gene-Related Cerebellar Neurodegeneration in SCA3/MJD: A Case-Controlled Imaging-Genetic Study.

Front Neurol 2020;11:30. Epub 2020 Feb 7.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fneur.2020.00030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019006PMC
February 2020

Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17.

Nat Commun 2020 02 27;11(1):1101. Epub 2020 Feb 27.

Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, Guangzhou, China.

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http://dx.doi.org/10.1038/s41467-020-14931-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046734PMC
February 2020

Profiling of mitochondrial genomes in SCA3/MJD patients from mainland China.

Gene 2020 May 19;738:144487. Epub 2020 Feb 19.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Diseases, Central South University, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, China; Xinjiang Medical University, Urumchi, Xinjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2020.144487DOI Listing
May 2020

Identification of expanded repeats in NOTCH2NLC in neurodegenerative dementias.

Neurobiol Aging 2020 05 24;89:142.e1-142.e7. Epub 2020 Jan 24.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Central South University, Changsha, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.01.010DOI Listing
May 2020

Corrigendum to "Generation of an induced pluripotent stem cell line (XHCSUi001-A) from urine cells of a patient with spinocerebellar ataxia type 3" [Stem Cell Research Vol 40 (2019) 101555].

Stem Cell Res 2020 03 30;43:101715. Epub 2020 Jan 30.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Diseases, Central South University, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, China; Xinjiang Medical University, Urumchi, Xinjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2020.101715DOI Listing
March 2020

The UFM1 cascade times mitosis entry associated with microcephaly.

FASEB J 2020 01 29;34(1):1319-1330. Epub 2019 Nov 29.

Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.

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http://dx.doi.org/10.1096/fj.201901751RDOI Listing
January 2020

PRRT2 frameshift mutation reduces its mRNA stability resulting loss of function in paroxysmal kinesigenic dyskinesia.

Biochem Biophys Res Commun 2020 02 27;522(3):553-559. Epub 2019 Nov 27.

Key Laboratory of Hunan Province in Neurodegenerative Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China; Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981028PMC
February 2020

Clinical findings of autosomal-dominant striatal degeneration and PDE8B mutation screening in parkinsonism and related disorders.

Parkinsonism Relat Disord 2019 12 5;69:94-98. Epub 2019 Nov 5.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, PR China; National Clinical Research Center for Geriatric Diseases, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, PR China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, 410008, PR China; Center for Medical Genetics, School of Life Sciences, Central South University, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.11.002DOI Listing
December 2019

Mutation analysis of GLT8D1 and ARPP21 genes in amyotrophic lateral sclerosis patients from mainland China.

Neurobiol Aging 2020 01 25;85:156.e1-156.e4. Epub 2019 Sep 25.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China; National Clinical Research Center for Geriatric Diseases, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, People's Republic of China; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.09.013DOI Listing
January 2020

Gene4Denovo: an integrated database and analytic platform for de novo mutations in humans.

Nucleic Acids Res 2020 01;48(D1):D913-D926

National Clinical Research Centre for Geriatric Disorders, Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1093/nar/gkz923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145562PMC
January 2020

Gene-Related Cerebellar Neurodegeneration in SCA3/MJD: A Case-Controlled Imaging-Genetic Study.

Front Neurol 2019 24;10:1025. Epub 2019 Sep 24.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fneur.2019.01025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768953PMC
September 2019

Generation of an induced pluripotent stem cell line (XHCSUi001-A) from urine cells of a patient with spinocerebellar ataxia type 3.

Stem Cell Res 2019 10 27;40:101555. Epub 2019 Aug 27.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Diseases, Central South University, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, China; Xinjiang Medical University, Urumchi, Xinjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101555DOI Listing
October 2019

Genetic and clinical analyses of spinocerebellar ataxia type 8 in mainland China.

J Neurol 2019 Dec 30;266(12):2979-2986. Epub 2019 Aug 30.

Department of Neurology, Xiangya Hospital, Central South University, 87 Xiangya Rd, Changsha, Hunan, People's Republic of China.

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http://dx.doi.org/10.1007/s00415-019-09519-2DOI Listing
December 2019

Factors Associated With Dyskinesia in Parkinson's Disease in Mainland China.

Front Neurol 2019 15;10:477. Epub 2019 May 15.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fneur.2019.00477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536088PMC
May 2019

Identification of a potential exosomal biomarker in spinocerebellar ataxia Type 3/Machado-Joseph disease.

Epigenomics 2019 07 30;11(9):1037-1056. Epub 2019 May 30.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China.

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http://dx.doi.org/10.2217/epi-2019-0081DOI Listing
July 2019

Long Noncoding RNA Analyses for Osteoporosis Risk in Caucasian Women.

Calcif Tissue Int 2019 08 9;105(2):183-192. Epub 2019 May 9.

Center of Genomics and Bioinformatics, Tulane University, New Orleans, LA, 70112, USA.

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http://dx.doi.org/10.1007/s00223-019-00555-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712977PMC
August 2019

A novel WARS mutation (p.Asp314Gly) identified in a Chinese distal hereditary motor neuropathy family.

Clin Genet 2019 08 27;96(2):176-182. Epub 2019 May 27.

Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.1111/cge.13563DOI Listing
August 2019

Association of HIF1A and Parkinson's disease in a Han Chinese population demonstrated by molecular inversion probe analysis.

Neurol Sci 2019 Sep 25;40(9):1927-1931. Epub 2019 Apr 25.

Department of Neurology, Xiangya Hospital, Central South University, 87# Xiangya Road, Changsha, 410008, Hunan, China.

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http://dx.doi.org/10.1007/s10072-019-03905-4DOI Listing
September 2019

Genetic analysis of DNA methylation and hydroxymethylation genes in Parkinson's disease.

Neurobiol Aging 2019 12 11;84:242.e13-242.e16. Epub 2019 Mar 11.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Changsha, Hunan, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.02.025DOI Listing
December 2019

MicroRNAs in Alzheimer's Disease.

Front Genet 2019 1;10:153. Epub 2019 Mar 1.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fgene.2019.00153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405631PMC
March 2019

The Effects of rs894278 on Resting-State Brain Activity in Parkinson's Disease.

Front Neurosci 2019 4;13:47. Epub 2019 Feb 4.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fnins.2019.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369188PMC
February 2019

A Comprehensive Analysis of Population Differences in Variant Distribution in Parkinson's Disease.

Front Aging Neurosci 2019 30;11:13. Epub 2019 Jan 30.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fnagi.2019.00013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363667PMC
January 2019

MicroRNA-26a/Death-Associated Protein Kinase 1 Signaling Induces Synucleinopathy and Dopaminergic Neuron Degeneration in Parkinson's Disease.

Biol Psychiatry 2019 05 19;85(9):769-781. Epub 2018 Dec 19.

Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Institute of Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China; National Research Center for Geriatric Diseases, Xiangya Hospital, and Center for Medical Genetics, School of Life Science, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.12.008DOI Listing
May 2019

Direct and selective lineage conversion of human fibroblasts to dopaminergic precursors.

Neurosci Lett 2019 04 18;699:16-23. Epub 2019 Jan 18.

Department of Pharmacology & Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, 68198, United States; Center for Translational Neurodegeneration and Regenerative Therapy, Shanghai Tenth People's Hospital affiliated to Tongji University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2019.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443443PMC
April 2019

Gastrointestinal Dysfunctions Are Associated with Variants in Parkinson's Disease.

Parkinsons Dis 2018 5;2018:5908359. Epub 2018 Dec 5.

National Clinical Research Center for Geriatric Disorders, Changsha, Hunan 410078, China.

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http://dx.doi.org/10.1155/2018/5908359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304865PMC
December 2018

Genetic Impact on Clinical Features in Parkinson's Disease: A Study on -rs11931074.

Parkinsons Dis 2018 3;2018:2754541. Epub 2018 Dec 3.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.

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http://dx.doi.org/10.1155/2018/2754541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304873PMC
December 2018

Systematically analyzing rare variants of autosomal-dominant genes for sporadic Parkinson's disease in a Chinese cohort.

Neurobiol Aging 2019 04 20;76:215.e1-215.e7. Epub 2018 Nov 20.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China; National Clinical Research Center for Geriatric Medicine, Changsha, Hunan, P.R. China; Key of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, P.R. China; Parkinson's Disease Center of Beijing Institute for Brain Disorders, Beijing, P.R. China; Collaborative Innovation Center for Brain Science, Shanghai, P.R. China; Collaborative Innovation Center for Genetics and Development, Shanghai, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.11.012DOI Listing
April 2019

Polymorphisms in DNA methylation-related genes are linked to the phenotype of Machado-Joseph disease.

Neurobiol Aging 2019 03 16;75:225.e1-225.e8. Epub 2018 Nov 16.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China; State Key Laboratory of Medical Genetics, Central South University, Changsha, Hunan, P.R. China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, P.R. China; Xinjiang Medical University, Xinjiang, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.11.002DOI Listing
March 2019

Rare variants in patients with frontotemporal dementia and amyotrophic lateral sclerosis in a Chinese cohort.

Transl Neurodegener 2018 4;7:31. Epub 2018 Dec 4.

1Department of Neurology, Xiangya Hospital, Central South University, 87 Xiangya Rd, Changsha, 410008 China.

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http://dx.doi.org/10.1186/s40035-018-0136-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278101PMC
December 2018

Conditional Haploinsufficiency of β-Catenin Aggravates Neuronal Damage in a Paraquat-Based Mouse Model of Parkinson Disease.

Mol Neurobiol 2019 Jul 6;56(7):5157-5166. Epub 2018 Dec 6.

Department of Pathology, Case Western Reserve University, 2103 Cornell Road, Cleveland, OH, 44106, USA.

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http://dx.doi.org/10.1007/s12035-018-1431-zDOI Listing
July 2019

The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease.

Brain Pathol 2019 07 28;29(4):530-543. Epub 2019 Jan 28.

Department of Pathology, Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1111/bpa.12691DOI Listing
July 2019

Standardized Operational Protocol for Human Brain Banking in China.

Neurosci Bull 2019 Apr 8;35(2):270-276. Epub 2018 Nov 8.

Department of Human Anatomy, Histology and Embryology, Institute of Basic Medical Sciences, Neuroscience Center, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 10005, China.

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http://link.springer.com/10.1007/s12264-018-0306-7
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http://dx.doi.org/10.1007/s12264-018-0306-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426885PMC
April 2019

A Comprehensive Analysis of the Association Between Polymorphisms and the Risk of Parkinson's Disease.

Front Mol Neurosci 2018 25;11:391. Epub 2018 Oct 25.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fnmol.2018.00391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209653PMC
October 2018

Recent Advances in Biomarkers for Parkinson's Disease.

Front Aging Neurosci 2018 11;10:305. Epub 2018 Oct 11.

National Clinical Research Center for Geriatric Disorders, Changsha, China.

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http://dx.doi.org/10.3389/fnagi.2018.00305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193101PMC
October 2018

A Meta-Analysis of -Related Clinical Symptoms in Parkinson's Disease.

Parkinsons Dis 2018 27;2018:3136415. Epub 2018 Sep 27.

National Clinical Research Center for Geriatric Disorders, Changsha, Hunan 410078, China.

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http://dx.doi.org/10.1155/2018/3136415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180987PMC
September 2018

Familial amyloid polyneuropathy with chronic paroxysmal dry cough in Mainland China: A Chinese family with a proven heterozygous missense mutation c.349G>T in the transthyretin gene.

J Clin Neurosci 2019 Feb 22;60:164-166. Epub 2018 Oct 22.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Central South University, Changsha, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, China; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183142
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http://dx.doi.org/10.1016/j.jocn.2018.10.040DOI Listing
February 2019

Genetic modifiers of age-at-onset in polyglutamine diseases.

Ageing Res Rev 2018 Dec 21;48:99-108. Epub 2018 Oct 21.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, PR China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, 410078, PR China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, 410008, PR China; Xinjiang Medical University, Xinjiang, 830011, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15681637183006
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http://dx.doi.org/10.1016/j.arr.2018.10.004DOI Listing
December 2018

Clinical Heterogeneity Among Variants in Parkinson's Disease: A Meta-Analysis.

Front Aging Neurosci 2018 19;10:283. Epub 2018 Sep 19.

National Clinical Research Center for Geriatric Disorders, Changsha, China.

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http://dx.doi.org/10.3389/fnagi.2018.00283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156433PMC
September 2018

Roles of Post-translational Modifications in Spinocerebellar Ataxias.

Front Cell Neurosci 2018 19;12:290. Epub 2018 Sep 19.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

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https://www.frontiersin.org/article/10.3389/fncel.2018.00290
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http://dx.doi.org/10.3389/fncel.2018.00290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156280PMC
September 2018

Two cases of CLIPPERS with increased number of perivascular CD20-positive B lymphocytes.

Brain 2018 10;141(10):e75

Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1093/brain/awy234DOI Listing
October 2018

Novel Epigenetic Techniques Provided by the CRISPR/Cas9 System.

Stem Cells Int 2018 8;2018:7834175. Epub 2018 Jul 8.

Department of Geriatric Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.

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https://www.hindawi.com/journals/sci/2018/7834175/
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http://dx.doi.org/10.1155/2018/7834175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079388PMC
July 2018

Clinical characteristics of PD patients with LRRK2 G2385R and R1628P variants.

Neurosci Lett 2018 10 16;685:185-189. Epub 2018 Aug 16.

Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; National Clinical Research Center for Geriatric Disorders, Changsha, Hunan 410078, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan 410008, China. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2018.08.015DOI Listing
October 2018

Cerebellar lncRNA Expression Profile Analysis of SCA3/MJD Mice.

Int J Genomics 2018 25;2018:5383517. Epub 2018 Jun 25.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.

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http://dx.doi.org/10.1155/2018/5383517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036799PMC
June 2018

Investigation on modulation of DNA repair pathways in Chinese MJD patients.

Neurobiol Aging 2018 11 28;71:267.e5-267.e6. Epub 2018 Jun 28.

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China; Laboratory of Medical Genetics, Central South University, Changsha, Hunan, P. R. China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan, P. R. China; Xinjiang Medical University, Xinjiang, P. R. China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183022
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.06.024DOI Listing
November 2018

A novel AIFM1 mutation in a Chinese family with X-linked Charcot-Marie-Tooth disease type 4.

Neuromuscul Disord 2018 08 26;28(8):652-659. Epub 2018 May 26.

Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2018.05.008DOI Listing
August 2018