Publications by authors named "Behzad Javaheri"

33Publications

Long-term bisphosphonate treatment coupled with ovariectomy in mice provokes deleterious effects on femoral neck fracture pattern and modifies tibial shape.

Authors:
Samuel Monzem Rafael Y Ballester Behzad Javaheri Blandine Poulet Dábila A Sônego Andrew A Pitsillides Roberto L Souza

Bone Jt Open 2020 Sep 1;1(9):512-519. Epub 2020 Sep 1.

Veterinary College, Federal University of Mato Grosso, Cuiaba, Mato Grosso, Brazil.

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September 2020

Loss of Adenylyl Cyclase 6 in Leptin Receptor-Expressing Stromal Cells Attenuates Loading-Induced Endosteal Bone Formation.

Authors:
Mathieu Riffault Gillian P Johnson Madeline M Owen Behzad Javaheri Andrew A Pitsillides David A Hoey

JBMR Plus 2020 Nov 14;4(11):e10408. Epub 2020 Oct 14.

Trinity Centre for Biomedical Engineering Trinity Biomedical Sciences Institute, Trinity College Dublin Dublin Ireland.

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November 2020

Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis.

Authors:
Lorenzo Ramos-Mucci Behzad Javaheri Rob van 't Hof George Bou-Gharios Andrew A Pitsillides Eithne Comerford Blandine Poulet

Arthritis Res Ther 2020 07 16;22(1):171. Epub 2020 Jul 16.

Institute of Lifecourse and Medical Sciences, University of Liverpool, 6 West Derby street, L7 8TX, Liverpool, UK.

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July 2020

Lasting organ-level bone mechanoadaptation is unrelated to local strain.

Authors:
Behzad Javaheri Hajar Razi Stephanie Gohin Sebastian Wylie Yu-Mei Chang Phil Salmon Peter D Lee Andrew A Pitsillides

Sci Adv 2020 03 6;6(10):eaax8301. Epub 2020 Mar 6.

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, Royal College Street, London NW1 0TU, UK.

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March 2020

Applied mechanical loading to mouse hindlimb acutely increases skeletal perfusion and chronically enhanced vascular porosity.

Authors:
Stephanie Gohin Behzad Javaheri Mark Hopkinson Andrew Anthony Pitsillides Timothy R Arnett Chantal Chenu

J Appl Physiol (1985) 2020 04 12;128(4):838-846. Epub 2020 Mar 12.

Department of Comparative Biomedical Sciences, Royal Veterinary College, London, United Kingdom.

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April 2020

Correction to: Aging and Mechanoadaptive Responsiveness of Bone.

Authors:
Behzad Javaheri Andrew A Pitsillides

Curr Osteoporos Rep 2020 Jan 6. Epub 2020 Jan 6.

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.

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January 2020

In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography.

Authors:
Kamel Madi Katherine A Staines Brian K Bay Behzad Javaheri Hua Geng Andrew J Bodey Sarah Cartmell Andrew A Pitsillides Peter D Lee

Nat Biomed Eng 2020 03 25;4(3):343-354. Epub 2019 Nov 25.

Research Complex at Harwell, RAL, Didcot, UK.

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March 2020

Aging and Mechanoadaptive Responsiveness of Bone.

Authors:
Behzad Javaheri Andrew A Pitsillides

Curr Osteoporos Rep 2019 12;17(6):560-569

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.

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December 2019

Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis.

Authors:
Katherine A Staines Ekele Ikpegbu Anna E Törnqvist Scott Dillon Behzad Javaheri Anish K Amin Dylan N Clements David J Buttle Andrew A Pitsillides Colin Farquharson

BMC Musculoskelet Disord 2019 Jul 27;20(1):344. Epub 2019 Jul 27.

Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian, UK.

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July 2019

Regulation of the Bone Vascular Network is Sexually Dimorphic.

Authors:
Alice Goring Aikta Sharma Behzad Javaheri Rosanna Cg Smith Janos M Kanczler Alan Boyde Eric Hesse Sumeet Mahajan Bjorn R Olsen Andrew A Pitsillides Philipp Schneider Richard Oc Oreffo Claire E Clarkin

J Bone Miner Res 2019 11 9;34(11):2117-2132. Epub 2019 Oct 9.

School of Biological Sciences, University of Southampton, Southampton, UK.

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November 2019

In Vivo Models of Mechanical Loading.

Authors:
Behzad Javaheri Nathalie Bravenboer Astrid D Bakker Albert van der Veen Roberto Lopes de Souza Leanne Saxon Andrew A Pitsillides

Methods Mol Biol 2019 ;1914:369-390

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, London, UK.

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June 2019

Using Cell and Organ Culture Models to Analyze Responses of Bone Cells to Mechanical Stimulation.

Authors:
Soraia P Caetano-Silva Astrid Novicky Behzad Javaheri Simon C F Rawlinson Andrew A Pitsillides

Methods Mol Biol 2019 ;1914:99-128

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, London, UK.

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June 2019

Sost Haploinsufficiency Provokes Peracute Lethal Cardiac Tamponade without Rescuing the Osteopenia in a Mouse Model of Excess Glucocorticoids.

Authors:
Behzad Javaheri Eleanor Herbert Mark Hopkinson Ahmed Al-Jazzar Andrew A Pitsillides

Am J Pathol 2019 04 19;189(4):753-761. Epub 2019 Jan 19.

Department of Comparative Biomedical Sciences, The Royal Veterinary College, London, United Kingdom. Electronic address:

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April 2019

Targeted Inhibition of Aggrecanases Prevents Articular Cartilage Degradation and Augments Bone Mass in the STR/Ort Mouse Model of Spontaneous Osteoarthritis.

Authors:
Ioannis Kanakis Ke Liu Blandine Poulet Behzad Javaheri Rob J van 't Hof Andrew A Pitsillides George Bou-Gharios

Arthritis Rheumatol 2019 04 14;71(4):571-582. Epub 2019 Feb 14.

University of Liverpool, Liverpool, UK.

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April 2019

Studying Osteoarthritis Pathogenesis in Mice.

Authors:
Andrew Blease Patricia Das Neves Borges Marcia Curtinha Behzad Javaheri Isabell S von Loga Ida Parisi Jadwiga Zarebska Andrew Pitsillides Tonia L Vincent Paul K Potter

Curr Protoc Mouse Biol 2018 Dec 21;8(4):e50. Epub 2018 Sep 21.

Disease Model Discovery, Mammalian Genetics Unit, MRC Harwell Institute, Oxfordshire, United Kingdom.

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December 2018

Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response.

Authors:
Behzad Javaheri Alessandra Carriero Maria Wood Roberto De Souza Peter D Lee Sandra Shefelbine Andrew A Pitsillides

Sci Rep 2018 04 27;8(1):6636. Epub 2018 Apr 27.

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.

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April 2018

The Chondro-Osseous Continuum: Is It Possible to Unlock the Potential Assigned Within?

Authors:
Behzad Javaheri Soraia P Caetano-Silva Ioannis Kanakis George Bou-Gharios Andrew A Pitsillides

Front Bioeng Biotechnol 2018 21;6:28. Epub 2018 Mar 21.

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, London, United Kingdom.

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March 2018

A Computed Microtomography Method for Understanding Epiphyseal Growth Plate Fusion.

Authors:
Katherine A Staines Kamel Madi Behzad Javaheri Peter D Lee Andrew A Pitsillides

Front Mater 2018 Jan;4:48

Comparative Biomedical Sciences, Royal Veterinary College, London, United Kingdom.

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January 2018

Deficiency does not Alter Bone's Lacunar or Vascular Porosity in Mice.

Authors:
Henry Mosey Juan A Núñez Alice Goring Claire E Clarkin Katherine A Staines Peter D Lee Andrew A Pitsillides Behzad Javaheri

Front Mater 2017 Sep;4:27

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, London, United Kingdom.

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September 2017

Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis.

Authors:
Behzad Javaheri Blandine Poulet Ahmed Aljazzar Roberto de Souza Miriam Piles Mark Hopkinson Elaine Shervill Andrea Pollard Boris Chan Yu-Mei Chang Isabel R Orriss Peter D Lee Andrew A Pitsillides

Bone 2017 Oct 1;103:308-317. Epub 2017 Aug 1.

Skeletal Biology Group, Comparative Biomedical Sciences, The Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.

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October 2017

A distinctive patchy osteomalacia characterises Phospho1-deficient mice.

Authors:
Alan Boyde Katherine A Staines Behzad Javaheri Jose Luis Millan Andrew A Pitsillides Colin Farquharson

J Anat 2017 Aug;231(2):298-308

Roslin Institute and R(D)SVS, The University of Edinburgh, Midlothian, UK.

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August 2017

Corrigendum: Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes.

Authors:
Rosemary F L Suswillo Behzad Javaheri Simon C F Rawlinson Gary P Dowthwaite Lance E Lanyon Andrew A Pitsillides

Cell Biochem Funct 2017 06;35(4):244

Comparative Biomedical Sciences, Royal Veterinary College, London, UK.

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June 2017

Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation.

Authors:
Katherine A Staines Behzad Javaheri Peter Hohenstein Robert Fleming Ekele Ikpegbu Erin Unger Mark Hopkinson David J Buttle Andrew A Pitsillides Colin Farquharson

J Cell Physiol 2017 Nov 14;232(11):3006-3019. Epub 2017 Jun 14.

Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian, UK.

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November 2017

Altered Bone Mechanics, Architecture and Composition in the Skeleton of TIMP-3-Deficient Mice.

Authors:
Brendyn Miller Lyudmila Spevak Lyudmila Lukashova Behzad Javaheri Andrew A Pitsillides Adele Boskey George Bou-Gharios Alessandra Carriero

Calcif Tissue Int 2017 06 24;100(6):631-640. Epub 2017 Feb 24.

Department of Biomedical Engineering, Florida Institute of Technology, Melbourne, FL, USA.

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June 2017

Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling.

Authors:
Daniel C Berwick Behzad Javaheri Andrea Wetzel Mark Hopkinson Jonathon Nixon-Abell Simone Grannò Andrew A Pitsillides Kirsten Harvey

Mol Neurodegener 2017 01 19;12(1). Epub 2017 Jan 19.

Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.

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January 2017

Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes.

Authors:
Rosemary F L Suswillo Behzad Javaheri Simon C F Rawlinson Gary P Dowthwaite Lance E Lanyon Andrew A Pitsillides

Cell Biochem Funct 2017 Jan;35(1):56-65

Comparative Biomedical Sciences, Royal Veterinary College, London, UK.

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January 2017

Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues.

Authors:
Ahmed Al-Jazzar Behzad Javaheri Matt Prideaux Alan Boyde Cheryl L Scudamore Chahrazad Cherifi Eric Hay Mark Hopkinson Michael Boyd Martine Cohen-Solal Colin Farquharson Andrew A Pitsillides

Int J Mol Sci 2016 Dec 26;18(1). Epub 2016 Dec 26.

Skeletal Biology Group, Comparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London NW1 0TU, UK.

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December 2016

Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo.

Authors:
Behzad Javaheri Mark Hopkinson Blandine Poulet Andrea S Pollard Sandra J Shefelbine Yu-Mei Chang Philippa Francis-West George Bou-Gharios Andrew A Pitsillides

PLoS One 2016 12;11(8):e0159657. Epub 2016 Aug 12.

Department of Comparative Biomedical Sciences, The Royal Veterinary College, London, United Kingdom.

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July 2017

Preclinical models for in vitro mechanical loading of bone-derived cells.

Authors:
Robin Michael Delaine-Smith Behzad Javaheri Jennifer Helen Edwards Marisol Vazquez Robin Mark Howard Rumney

Bonekey Rep 2015 19;4:728. Epub 2015 Aug 19.

Academic Unit of Bone Biology, Department of Human Metabolism, University of Sheffield Medical School , Sheffield, UK.

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September 2015

Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading.

Authors:
Behzad Javaheri Amber Rath Stern Nuria Lara Mark Dallas Hong Zhao Ying Liu Lynda F Bonewald Mark L Johnson

J Bone Miner Res 2014 Mar;29(3):705-15

The Royal Veterinary College, London, UK.

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March 2014

Lrp5 is not required for the proliferative response of osteoblasts to strain but regulates proliferation and apoptosis in a cell autonomous manner.

Authors:
Behzad Javaheri Andrew Sunters Gul Zaman Rosemary F L Suswillo Leanne K Saxon Lance E Lanyon Joanna S Price

PLoS One 2012 2;7(5):e35726. Epub 2012 May 2.

Department of Oral Biology, UMKC School of Dentistry, Kansas City, Missouri, United States of America.

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September 2012

Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent.

Authors:
Gul Zaman Andrew Sunters Gabriel L Galea Behzad Javaheri Leanne K Saxon Alaa Moustafa Victoria J Armstrong Joanna S Price Lance E Lanyon

J Biol Chem 2012 Feb 2;287(6):3946-62. Epub 2011 Nov 2.

Department of Veterinary Basic Sciences, Royal Veterinary College, London, NW1 0TU, United Kingdom.

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February 2012

The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading.

Authors:
Alaa Moustafa Toshihiro Sugiyama Leanne K Saxon Gul Zaman Andrew Sunters Victoria J Armstrong Behzad Javaheri Lance E Lanyon Joanna S Price

Bone 2009 May 14;44(5):930-5. Epub 2009 Jan 14.

Department of Veterinary Basic Sciences, The Royal Veterinary College, University of London, London, UK.

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May 2009