Beatriz Apellaniz

Beatriz Apellaniz

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Beatriz Apellaniz

Beatriz Apellaniz

Publications by authors named "Beatriz Apellaniz"

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18Publications

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Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions.

Nat Commun 2019 01 8;10(1):78. Epub 2019 Jan 8.

Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080, Bilbao, Spain.

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http://dx.doi.org/10.1038/s41467-018-07962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325134PMC
January 2019

Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds.

Biochim Biophys Acta Biomembr 2018 Jun 23;1860(6):1259-1271. Epub 2018 Feb 23.

Biofisika Institute (CSIC, UPV/EHU), Biochemistry and Molecular Biology Department, University of the Basque Country (UPV/EHU), PO Box 644, 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2018.02.019DOI Listing
June 2018

The Use of Liposomes to Shape Epitope Structure and Modulate Immunogenic Responses of Peptide Vaccines Against HIV MPER.

Adv Protein Chem Struct Biol 2015 18;99:15-54. Epub 2015 Apr 18.

Biophysics Unit (CSIC, UPV/EHU), University of the Basque Country (UPV/EHU), Bilbao, Spain; Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/bs.apcsb.2015.03.002DOI Listing
December 2017

Effects of HIV-1 gp41-Derived Virucidal Peptides on Virus-like Lipid Membranes.

Biophys J 2017 Sep 7;113(6):1301-1310. Epub 2017 Aug 7.

Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.06.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607204PMC
September 2017

Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.

Sci Rep 2016 12 1;6:38177. Epub 2016 Dec 1.

Biophysics Unit (CSIC, UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1038/srep38177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131266PMC
December 2016

The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region.

J Biol Chem 2015 May 18;290(21):12999-3015. Epub 2015 Mar 18.

From the Biophysics Unit (Consejo Superior de Investigaciones Científicas, UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), P. O. Box 644, 48080 Bilbao, Spain,

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http://dx.doi.org/10.1074/jbc.M115.644351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505554PMC
May 2015

Fusion-competent state induced by a C-terminal HIV-1 fusion peptide in cholesterol-rich membranes.

Biochim Biophys Acta 2015 Apr 21;1848(4):1014-22. Epub 2015 Jan 21.

Biophysics Unit (CSIC, UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2015.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331211PMC
April 2015

The three lives of viral fusion peptides.

Chem Phys Lipids 2014 Jul 2;181:40-55. Epub 2014 Apr 2.

Biophysics Unit (CSIC-UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2014.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061400PMC
July 2014

Mechanism of membrane perturbation by the HIV-1 gp41 membrane-proximal external region and its modulation by cholesterol.

Biochim Biophys Acta 2012 Nov 9;1818(11):2521-8. Epub 2012 Jun 9.

BCPS Department, Illinois Institute of Technology, Chicago, IL 60616, USA.

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http://dx.doi.org/10.1016/j.bbamem.2012.06.002DOI Listing
November 2012

Membrane-proximal external HIV-1 gp41 motif adapted for destabilizing the highly rigid viral envelope.

Biophys J 2011 Nov 15;101(10):2426-35. Epub 2011 Nov 15.

Biophysics Unit (CSIC-UPV/EHU) and Department of Biochemistry and Molecular Biology, University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/j.bpj.2011.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218338PMC
November 2011

A new paradigm in molecular recognition? Specific antibody binding to membrane-inserted HIV-1 epitopes.

J Mol Recognit 2011 Jul-Aug;24(4):642-6

Biophysics Unit (CSIC-UPV/EHU) and Biochemistry Department, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1002/jmr.1092DOI Listing
September 2011

Destabilization exerted by peptides derived from the membrane-proximal external region of HIV-1 gp41 in lipid vesicles supporting fluid phase coexistence.

Biochim Biophys Acta 2011 Jul 18;1808(7):1797-805. Epub 2011 Feb 18.

Departamento de Bioquímica, Universidad del País Vasco, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/j.bbamem.2011.02.005DOI Listing
July 2011

All-or-none versus graded: single-vesicle analysis reveals lipid composition effects on membrane permeabilization.

Biophys J 2010 Dec;99(11):3619-28

Unidad de Biofísica, Consejo Superior de Investigaciones Científicas/University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/j.bpj.2010.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998612PMC
December 2010

Confocal microscopy of giant vesicles supports the absence of HIV-1 neutralizing 2F5 antibody reactivity to plasma membrane phospholipids.

FEBS Lett 2010 Apr 17;584(8):1591-6. Epub 2010 Mar 17.

Biophysics Unit (CSIC-UPV/EHU), Biochemistry and Molecular Biology Department, University of the Basque Country, Bilbao, Spain.

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http://doi.wiley.com/10.1016/j.febslet.2010.03.021
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http://dx.doi.org/10.1016/j.febslet.2010.03.021DOI Listing
April 2010

Distinct mechanisms of lipid bilayer perturbation induced by peptides derived from the membrane-proximal external region of HIV-1 gp41.

Biochemistry 2009 Jun;48(23):5320-31

Unidad de Biofisica (CSIC-UPV/EHU) and Departamento de Bioquimica, Universidad del Pais Vasco, Aptdo. 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1021/bi900504tDOI Listing
June 2009