Beatrice Knudsen

Beatrice Knudsen

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Beatrice Knudsen

Publications by authors named "Beatrice Knudsen"

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Centrosome loss results in an unstable genome and malignant prostate tumors.

Oncogene 2019 Sep 2. Epub 2019 Sep 2.

Department of Cellular and Molecular Medicine, University of Arizona Cancer Center, University of Arizona, Tucson, AZ, 85724, USA.

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http://dx.doi.org/10.1038/s41388-019-0995-zDOI Listing
September 2019

Procurement and Storage of Pleural and Peritoneal Fluids for Biobanking.

Methods Mol Biol 2019 ;1897:125-133

Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-8935-5_13DOI Listing
June 2019

A Multi-scale U-Net for Semantic Segmentation of Histological Images from Radical Prostatectomies.

AMIA Annu Symp Proc 2017 16;2017:1140-1148. Epub 2018 Apr 16.

Department of Bioengineering, University of California, Los Angeles, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977596PMC
April 2019

Effect of Preanalytic Variables on an Automated PTEN Immunohistochemistry Assay for Prostate Cancer.

Arch Pathol Lab Med 2019 03 8;143(3):338-348. Epub 2018 Oct 8.

From the Departments of Pathology (Drs Guedes, Morais, Fedor, Hicks, Gurel, De Marzo, and Lotan), Oncology (Drs Trock, De Marzo, and Lotan), and Urology (Drs Trock and De Marzo), Johns Hopkins University School of Medicine, Baltimore, Maryland; the Department of Pathology, New York University School of Medicine, New York, New York (Drs Melamed and Lee); the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (Drs Gopalan and Fine); the Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California (Dr Knudsen); the Department of Pathology, University of Washington, Seattle (Dr True); and Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York (Dr Scher).

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http://dx.doi.org/10.5858/arpa.2018-0068-OADOI Listing
March 2019

A method of quantifying centrosomes at the single-cell level in human normal and cancer tissue.

Mol Biol Cell 2019 03 30;30(7):811-819. Epub 2019 Jan 30.

Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724.

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https://www.molbiolcell.org/doi/10.1091/mbc.E18-10-0651
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http://dx.doi.org/10.1091/mbc.E18-10-0651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589791PMC
March 2019

Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential.

Cancer Res 2018 11 28;78(21):6086-6097. Epub 2018 Aug 28.

Division of Cancer Biology and Therapeutics, Department of Surgery and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0608DOI Listing
November 2018

An EM-based semi-supervised deep learning approach for semantic segmentation of histopathological images from radical prostatectomies.

Comput Med Imaging Graph 2018 11 3;69:125-133. Epub 2018 Sep 3.

Department of Bioengineering, University of California, Los Angeles, CA, USA; Computational Integrated Diagnostics, Departments of Radiological Sciences and Pathology and Laboratory Medicine, University of California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.compmedimag.2018.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173982PMC
November 2018

Novel Regulation of Integrin Trafficking by Rab11-FIP5 in Aggressive Prostate Cancer.

Mol Cancer Res 2018 08 14;16(8):1319-1331. Epub 2018 May 14.

The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369592PMC
August 2018

A Non-integrating Lentiviral Approach Overcomes Cas9-Induced Immune Rejection to Establish an Immunocompetent Metastatic Renal Cancer Model.

Mol Ther Methods Clin Dev 2018 Jun 23;9:203-210. Epub 2018 Feb 23.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.omtm.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948229PMC
June 2018

Characterization of Laminin Binding Integrin Internalization in Prostate Cancer Cells.

J Cell Biochem 2017 05 5;118(5):1038-1049. Epub 2017 Jan 5.

The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724.

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http://dx.doi.org/10.1002/jcb.25673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553695PMC
May 2017

A basal cell defect promotes budding of prostatic intraepithelial neoplasia.

J Cell Sci 2017 01 8;130(1):104-110. Epub 2016 Sep 8.

Department of Cellular and Molecular Medicine, College of Medicine, University of Arizona Cancer Center, Tucson, AZ 85724, USA

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http://dx.doi.org/10.1242/jcs.188177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394777PMC
January 2017

Impact of treatment on progression to castration-resistance, metastases, and death in men with localized high-grade prostate cancer.

Cancer Med 2017 01 20;6(1):163-172. Epub 2016 Dec 20.

Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, California.

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http://dx.doi.org/10.1002/cam4.981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269571PMC
January 2017

The Cohesive Metastasis Phenotype in Human Prostate Cancer.

Biochim Biophys Acta 2016 12 24;1866(2):221-231. Epub 2016 Sep 24.

The University of Arizona Cancer Center, 1515 N. Campbell Ave., Tucson, AZ, 85724, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2016.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534328PMC
December 2016

Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome.

Cancer Res 2016 09 14;76(17):4948-58. Epub 2016 Jun 14.

Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047668PMC
http://dx.doi.org/10.1158/0008-5472.CAN-16-0902DOI Listing
September 2016

A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells.

Biochem Biophys Res Commun 2016 07 18;475(3):295-300. Epub 2016 May 18.

Departments of Biomedical Sciences and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Materials and Process Simulation Center, California Institute of Technology, Pasadena, CA, USA; GIRx Metabolics Inc., Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.04.149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918516PMC
July 2016

Application of a Clinical Whole-Transcriptome Assay for Staging and Prognosis of Prostate Cancer Diagnosed in Needle Core Biopsy Specimens.

J Mol Diagn 2016 05 3;18(3):395-406. Epub 2016 Mar 3.

Department of Urology, University of California San Francisco, San Francisco, California; Department of Anatomic Pathology, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1016/j.jmoldx.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851733PMC
May 2016

Rapid 3-D delineation of cell nuclei for high-content screening platforms.

Comput Biol Med 2016 Feb 25;69:328-38. Epub 2015 Apr 25.

Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.compbiomed.2015.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440328PMC
February 2016

Machine learning approaches to analyze histological images of tissues from radical prostatectomies.

Comput Med Imaging Graph 2015 Dec 20;46 Pt 2:197-208. Epub 2015 Aug 20.

Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048, USA; Department of Biomedical Sciences Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062020PMC
http://dx.doi.org/10.1016/j.compmedimag.2015.08.002DOI Listing
December 2015

Hypoxia after transarterial chemoembolization may trigger a progenitor cell phenotype in hepatocellular carcinoma.

Histopathology 2015 Oct 20;67(4):442-50. Epub 2015 Apr 20.

Departments of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/his.12623DOI Listing
October 2015

Docetaxel-induced polyploidization may underlie chemoresistance and disease relapse.

Cancer Lett 2015 Oct 13;367(2):89-92. Epub 2015 Jul 13.

Department of Biology, Georgia State University, Atlanta, GA 30303, USA; Institute of Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813805PMC
October 2015

Trading in your spindles for blebs: the amoeboid tumor cell phenotype in prostate cancer.

Asian J Androl 2014 Jul-Aug;16(4):530-5

Division of Cancer Biology and Therapeutics, Departments of Surgery, Medicine and Biomedical Sciences, and The Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA; Urological Diseases Research Center, Boston Children's Hospital; Department of Surgery, Harvard Medical School, Boston, MA and Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.4103/1008-682X.122877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104075PMC
August 2015

Regulation of microtubule dynamics by DIAPH3 influences amoeboid tumor cell mechanics and sensitivity to taxanes.

Sci Rep 2015 Jul 16;5:12136. Epub 2015 Jul 16.

1] Division of Cancer Biology and Therapeutics, Departments of Surgery and Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048 [2] Urological Diseases Research Center, Boston Children's Hospital, Boston, MA 02115 [3] Department of Surgery, Harvard Medical School, Boston, MA 02115.

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http://dx.doi.org/10.1038/srep12136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503992PMC
July 2015

Computerized delineation of nuclei in liquid-based pap smears stained with immunohistochemical biomarkers.

Cytometry B Clin Cytom 2015 Mar 3;88(2):110-9. Epub 2014 Oct 3.

Bioimage Informatics Laboratory, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California.

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http://dx.doi.org/10.1002/cyto.b.21193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188512PMC
March 2015

Active surveillance for prostate cancer: the role of the pathologist.

Pathology 2015 Jan;47(1):1-3

1Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand 2Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA 3Department of Oncology and Pathology, Karolinska University Hospital, Solna, Stockholm, Sweden 4Aquesta Pathology and University of Queensland, Brisbane, Qld, Australia 5Trillium Health Partners, Mississauga and McMaster University, Hamilton, ON, Canada 6Department of Pathology, Yale University School of Medicine, New Haven, CT, USA 7Institute for Precision Medicine and the Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell, University and New York-Presbyterian Hospital, New York, NY, USA 8Department of Pathology, Urology and Oncology, Johns Hopkins School of Medicine, Baltimore, MA, USA 9Department of Urology, University of Washington, Seattle, WA, USA 10Department of Surgery, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand 11Division of Urology, Sunnybrook Health Sciences, Centre, University of Toronto, Toronto, ON, Canada 12Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA 13Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 14Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA 15Section of Pathological Anatomy, Department of Biomedical Sciences and Public Health, Polytechnic University of the Marche Region (Ancona), Ancona, Italy 16University Health Network, University of Toronto, Toronto, Ontario, Canada 17Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, OH, USA 18Department of Cellular Pathology, The Royal London Hospital, London, UK 19Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA 20Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA 2

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http://dx.doi.org/10.1097/PAT.0000000000000186DOI Listing
January 2015

Effects of tissue decalcification on the quantification of breast cancer biomarkers by digital image analysis.

Diagn Pathol 2014 Nov 25;9:213. Epub 2014 Nov 25.

Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1186/s13000-014-0213-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252006PMC
November 2014

Detection of live circulating tumor cells by a class of near-infrared heptamethine carbocyanine dyes in patients with localized and metastatic prostate cancer.

PLoS One 2014 14;9(2):e88967. Epub 2014 Feb 14.

Uro-Oncolgy Research Laboratories, Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angles, California, United States of America ; Urologic Oncology Program, Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angles, California, United States of America ; Division of Hematology Oncology-Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088967PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925210PMC
October 2014

The critical role of the pathologist in determining eligibility for active surveillance as a management option in patients with prostate cancer: consensus statement with recommendations supported by the College of American Pathologists, International Society of Urological Pathology, Association of Directors of Anatomic and Surgical Pathology, the New Zealand Society of Pathologists, and the Prostate Cancer Foundation.

Arch Pathol Lab Med 2014 Oct 5;138(10):1387-405. Epub 2014 Aug 5.

From the Departments of Pathology and Laboratory Medicine (Drs Amin and Knudsen), Radiation Oncology (Dr Sandler), Urology (Dr Holden), and Biomedical Sciences (Dr Knudsen), Cedars-Sinai Medical Center, Los Angeles, California; the Departments of Urology (Drs Lin and Gore) and Pathology (Dr True), University of Washington, Seattle; Trillium Health Partners, Mississauga, Ontario, Canada, and McMaster University, Hamilton, Ontario, Canada (Dr Srigley); Aquesta Pathology, Toowong, Queensland, Australia, and the University of Queensland, Brisbane (Dr Samaratunga); the Department of Oncology and Pathology, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden (Dr Egevad); the Institute for Precision Medicine and the Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, Ithaca, New York, and New York-Presbyterian Hospital, New York (Dr Rubin); the Departments of Surgery (Dr Nacey) and Pathology and Molecular Medicine (Dr Delahunt), Wellington School of Medicine and Health Sciences, University of Otago, Newtown, Wellington, New Zealand; the James Buchanan Brady Urological Institute (Dr Carter) and the Departments of Pathology (Dr Epstein), Urology (Dr Epstein), and Oncology (Dr Epstein), Johns Hopkins School of Medicine, Baltimore, Maryland; Division of Urology, the Sunnybrook Health Sciences Centre (Dr Klotz) and the University Health Network (Dr Evans), University of Toronto, Toronto, Ontario, Canada; the Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston (Dr Zietman); the Section of Pathological Anatomy, Department of Biomedical Sciences and Public Health, Polytechnic University of the Marche Region, Ancona, Italy (Dr Montironi); the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut (Dr Humphrey); the Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, Ohio (Dr McKenney); the Department of Cell

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http://dx.doi.org/10.5858/arpa.2014-0219-SADOI Listing
October 2014

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Sonja I Berndt David V Conti Fredrick Schumacher Ying Han Sara Benlloch Dennis J Hazelett Zhaoming Wang Ed Saunders Daniel Leongamornlert Sara Lindstrom Sara Jugurnauth-Little Tokhir Dadaev Malgorzata Tymrakiewicz Daniel O Stram Kristin Rand Peggy Wan Alex Stram Xin Sheng Loreall C Pooler Karen Park Lucy Xia Jonathan Tyrer Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Merideth Yeager Laurie Burdette Charles C Chung Amy Hutchinson Kai Yu Chee Goh Mahbubl Ahmed Koveela Govindasami Michelle Guy Teuvo L J Tammela Anssi Auvinen Tiina Wahlfors Johanna Schleutker Tapio Visakorpi Katri A Leinonen Jianfeng Xu Markus Aly Jenny Donovan Ruth C Travis Tim J Key Afshan Siddiq Federico Canzian Kay-Tee Khaw Atsushi Takahashi Michiaki Kubo Paul Pharoah Nora Pashayan Maren Weischer Borge G Nordestgaard Sune F Nielsen Peter Klarskov Martin Andreas Røder Peter Iversen Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Janet L Stanford Suzanne Kolb Sarah Holt Beatrice Knudsen Antonio Hurtado Coll Susan M Gapstur W Ryan Diver Victoria L Stevens Christiane Maier Manuel Luedeke Kathleen Herkommer Antje E Rinckleb Sara S Strom Curtis Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Lisa Cannon-Albright Cezary Cybulski Dominika Wokołorczyk Wojciech Kluźniak Jong Park Thomas Sellers Hui-Yi Lin William B Isaacs Alan W Partin Hermann Brenner Aida Karina Dieffenbach Christa Stegmaier Constance Chen Edward L Giovannucci Jing Ma Meir Stampfer Kathryn L Penney Lorelei Mucci Esther M John Sue A Ingles Rick A Kittles Adam B Murphy Hardev Pandha Agnieszka Michael Andrzej M Kierzek William Blot Lisa B Signorello Wei Zheng Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Barbara Nemesure John Carpten Cristina Leske Suh-Yuh Wu Anselm Hennis Adam S Kibel Benjamin A Rybicki Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein S Lilly Zheng Jyotsna Batra Judith Clements Amanda Spurdle Manuel R Teixeira Paula Paulo Sofia Maia Chavdar Slavov Radka Kaneva Vanio Mitev John S Witte Graham Casey Elizabeth M Gillanders Daniella Seminara Elio Riboli Freddie C Hamdy Gerhard A Coetzee Qiyuan Li Matthew L Freedman David J Hunter Kenneth Muir Henrik Gronberg David E Neal Melissa Southey Graham G Giles Gianluca Severi Michael B Cook Hidewaki Nakagawa Fredrik Wiklund Peter Kraft Stephen J Chanock Brian E Henderson Douglas F Easton Rosalind A Eeles Christopher A Haiman

Nat Genet 2014 Oct 14;46(10):1103-9. Epub 2014 Sep 14.

1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [2] Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. [3].

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http://dx.doi.org/10.1038/ng.3094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383163PMC
October 2014

Statistical Methods for Tissue Array Images - Algorithmic Scoring and Co-training.

Ann Appl Stat 2012 Sep;6(3):1280-1305

Biostatistics and Biomathematics Program Fred Hutchinson Cancer Research Center Seattle, WA 98109.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441061PMC
http://dx.doi.org/10.1214/12-aoas543DOI Listing
September 2012

Mechanisms of prostate cancer initiation and progression.

Adv Cancer Res 2010 ;109:1-50

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1016/B978-0-12-380890-5.00001-6DOI Listing
February 2011

Activation of the MEK-S6 pathway in high-grade ovarian cancers.

Appl Immunohistochem Mol Morphol 2010 Dec;18(6):499-508

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1097/PAI.0b013e3181e53e1cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989426PMC
December 2010

DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines.

PLoS One 2010 Feb 22;5(2):e9359. Epub 2010 Feb 22.

Department of Biochemistry and Molecular Biology, University of Southern California, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009359PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825254PMC
February 2010

E-cadherin-mediated survival of androgen-receptor-expressing secretory prostate epithelial cells derived from a stratified in vitro differentiation model.

J Cell Sci 2010 Jan;123(Pt 2):266-76

Laboratory of Integrin Signaling and Tumorigenesis, Van Andel Research Institute, Grand Rapids, MI, USA.

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http://dx.doi.org/10.1242/jcs.054502DOI Listing
January 2010

Spectral analysis of multiplex Raman probe signatures.

ACS Nano 2008 Nov;2(11):2306-14

Biomedical/Life Sciences, Digital Health Group, Intel Corporation, Santa Clara, California 95054, USA.

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http://dx.doi.org/10.1021/nn800243gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662378PMC
November 2008

Raman nanoparticle probes for antibody-based protein detection in tissues.

J Histochem Cytochem 2008 Apr 10;56(4):371-9. Epub 2007 Dec 10.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, M5-A864, 1212 Aloha St., Seattle, WA 95054, USA.

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http://dx.doi.org/10.1369/jhc.7A7313.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2326103PMC
April 2008

Evaluation of the branched-chain DNA assay for measurement of RNA in formalin-fixed tissues.

J Mol Diagn 2008 Mar 14;10(2):169-76. Epub 2008 Feb 14.

Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seatle, Washington, USA.

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http://dx.doi.org/10.2353/jmoldx.2008.070127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259472PMC
March 2008

Showering c-MET-dependent cancers with drugs.

Curr Opin Genet Dev 2008 Feb 9;18(1):87-96. Epub 2008 Apr 9.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue, Seattle, WA 98109, United States.

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http://dx.doi.org/10.1016/j.gde.2008.02.001DOI Listing
February 2008

Composite organic-inorganic nanoparticles as Raman labels for tissue analysis.

Nano Lett 2007 Feb;7(2):351-6

Biomedical/Life Sciences, Digital Health Group, Intel Corporation, SC3-41, 2200 Mission College Boulevard, Santa Clara, California 95054, USA.

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http://dx.doi.org/10.1021/nl062453tDOI Listing
February 2007

Combining results of microarray experiments: a rank aggregation approach.

Stat Appl Genet Mol Biol 2006 20;5:Article15. Epub 2006 Jun 20.

Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.2202/1544-6115.1204DOI Listing
December 2006

Migrating with myosin VI.

Authors:
Beatrice Knudsen

Am J Pathol 2006 Nov;169(5):1523-6

Fred Hutchinson Cancer Research Center, Program in Cancer Biology, Division of Public Health Sciences, 1100 Fairview Avenue North, M5-A864, Seattle, WA 98109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780205PMC
http://dx.doi.org/10.2353/ajpath.2006.060712DOI Listing
November 2006

The impact of cell adhesion changes on proliferation and survival during prostate cancer development and progression.

J Cell Biochem 2006 Oct;99(2):345-61

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1002/jcb.20934DOI Listing
October 2006

Regulation of cell proliferation in a stratified culture system of epithelial cells from prostate tissue.

Cell Tissue Res 2006 Aug 24;325(2):263-76. Epub 2006 Mar 24.

Clinical Research and Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1007/s00441-005-0093-0DOI Listing
August 2006

The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms.

Cancer Res 2006 Jan;66(2):794-802

Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1716DOI Listing
January 2006

Proliferation and invasion: plasticity in tumor cells.

Proc Natl Acad Sci U S A 2005 Jul 15;102(30):10528-33. Epub 2005 Jul 15.

Laboratory of Molecular Oncology, Van Andel Research Institute, 333 Bostwick Avenue Northeast, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1073/pnas.0504367102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180792PMC
July 2005

Analyzing patterns of staining in immunohistochemical studies: application to a study of prostate cancer recurrence.

Cancer Epidemiol Biomarkers Prev 2005 May;14(5):1040-6

Translational and Outcomes Research, Fred Hutchinson Cancer Research Center, Mailstop M2-B230, 1100 Fairview Avenue North, P.O. Box 19024, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-04-0584DOI Listing
May 2005

Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma.

Int J Cancer 2005 Apr;114(4):563-71

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1002/ijc.20773DOI Listing
April 2005

C-Met overexpression in node-positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu.

Int J Cancer 2005 Feb;113(4):678-82

Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Mail Code 2050, 5841 South Maryland Avenue, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1002/ijc.20598DOI Listing
February 2005

Prostate cancer and the met hepatocyte growth factor receptor.

Adv Cancer Res 2004 ;91:31-67

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98125, USA.

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http://dx.doi.org/10.1016/S0065-230X(04)91002-0DOI Listing
November 2004

Basal prostate epithelial cells stimulate the migration of prostate cancer cells.

Mol Carcinog 2004 Oct;41(2):85-97

Department of Pathology, Weill Medical College of Cornell University, New York, NY, USA.

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http://dx.doi.org/10.1002/mc.20041DOI Listing
October 2004

Syndecan-1 expression in locally invasive and metastatic prostate cancer.

Urology 2004 Feb;63(2):402-7

Department of Urology, New York Presbyterian Hospital, New York, New York, USA.

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http://dx.doi.org/10.1016/j.urology.2003.08.036DOI Listing
February 2004

Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice.

Clin Cancer Res 2004 Jan;10(1 Pt 1):301-13

Departments of Pharmacology and Pathology, Weill Medical College of Cornell University, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.ccr-0999-3DOI Listing
January 2004

Radioimmunoscintigraphy of human met-expressing tumor xenografts using met3, a new monoclonal antibody.

Clin Cancer Res 2003 Sep;9(10 Pt 2):3839S-44S

Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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September 2003

Regulation of migration of primary prostate epithelial cells by secreted factors from prostate stromal cells.

Exp Cell Res 2003 Aug;288(2):246-56

Department of Pathology, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0014-4827(03)00204-0DOI Listing
August 2003

High expression of the Met receptor in prostate cancer metastasis to bone.

Urology 2002 Dec;60(6):1113-7

Department ofPathology, Weill Medical College of Cornell University, New York, New York, USA.

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http://dx.doi.org/10.1016/s0090-4295(02)01954-4DOI Listing
December 2002

Men with nonobstructive azoospermia have Leydig cell hypertrophy but not hyperplasia.

J Urol 2002 Sep;168(3):1068-70

Department of Urology, New York Presbyterian Hospital-Wiell Medical College of Cornell University, New York, NY, USA.

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http://dx.doi.org/10.1097/01.ju.0000026414.68954.d1DOI Listing
September 2002

Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens.

Cancer Res 2002 Mar;62(6):1654-61

Department of Pharmacology, Weill Medical College of Cornell University, New York, New York 10021, USA.

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March 2002