Publications by authors named "Beate I Escher"

192 Publications

Unravelling the chemical exposome in cohort studies: routes explored and steps to become comprehensive.

Environ Sci Eur 2021 11;33(1):17. Epub 2021 Feb 11.

Helmholtz Centre for Environmental Research GmbH - UFZ, Permoserstraße 15, 04318 Leipzig, Germany.

View Article and Find Full Text PDF
February 2021

Evaluation of an in vitro assay to screen for the immunotoxic potential of chemicals to fish.

Sci Rep 2021 Feb 4;11(1):3167. Epub 2021 Feb 4.

Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

View Article and Find Full Text PDF
February 2021

Effect-Based Trigger Values for Mixtures of Chemicals in Surface Water Detected with In Vitro Bioassays.

Environ Toxicol Chem 2021 Feb 13;40(2):487-499. Epub 2021 Jan 13.

Australian Rivers Institute, School of Environment and Science, Griffith University, Southport, Queensland, Australia.

View Article and Find Full Text PDF
February 2021

Bioavailable Environmental Pollutant Patterns in Sediments from Passive Equilibrium Sampling.

Environ Sci Technol 2020 Dec 19;54(24):15861-15871. Epub 2020 Nov 19.

Department of Cell Toxicology, UFZ Helmholtz Centre for Environmental Research, Permoserstr. 15, 04318 Leipzig, Germany.

View Article and Find Full Text PDF
December 2020

Wastewater treatment efficacy evaluated with bioassays.

Water Res X 2020 Dec 1;9:100072. Epub 2020 Oct 1.

Australian Rivers Institute, School of Environment and Science, Griffith University, Southport, QLD, 4222, Australia.

View Article and Find Full Text PDF
December 2020

Storm Event-Driven Occurrence and Transport of Dissolved and Sorbed Organic Micropollutants and Associated Effects in the Ammer River, Southwestern Germany.

Environ Toxicol Chem 2021 Jan 30;40(1):88-99. Epub 2020 Nov 30.

Center for Applied Geoscience, Eberhard Karls University of Tübingen, Tübingen, Germany.

View Article and Find Full Text PDF
January 2021

Mixture Risk Drivers in Freshwater Sediments and Their Bioavailability Determined Using Passive Equilibrium Sampling.

Environ Sci Technol 2020 10 2;54(20):13197-13206. Epub 2020 Oct 2.

Department of Cell Toxicology, UFZ - Helmholtz Centre for Environmental Research, Leipzig 04318, Germany.

View Article and Find Full Text PDF
October 2020

The Combined Algae Test for the Evaluation of Mixture Toxicity in Environmental Samples.

Environ Toxicol Chem 2020 12 5;39(12):2496-2508. Epub 2020 Nov 5.

Helmholtz Centre for Environmental Research, Leipzig, Germany.

View Article and Find Full Text PDF
December 2020

Optimization of a pre-metabolization procedure using rat liver S9 and cell-extracted S9 in the Ames fluctuation test.

Sci Total Environ 2020 Dec 6;749:141468. Epub 2020 Aug 6.

UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany; EWOMIS GmbH, Schießstraße 26c, 63486 Bruchköbel, Germany; Eberhard Karls University of Tübingen, Environmental Toxicology, Centre for Applied Geosciences, 72074 Tubingen, Germany.

View Article and Find Full Text PDF
December 2020

Direct sample introduction GC-MS/MS for quantification of organic chemicals in mammalian tissues and blood extracted with polymers without clean-up.

Anal Bioanal Chem 2020 Oct 15;412(26):7295-7305. Epub 2020 Aug 15.

Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research-UFZ, 04318, Leipzig, Germany.

View Article and Find Full Text PDF
October 2020

Cytotoxicity Burst? Differentiating Specific from Nonspecific Effects in Tox21 Reporter Gene Assays.

Environ Health Perspect 2020 07 23;128(7):77007. Epub 2020 Jul 23.

Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.

View Article and Find Full Text PDF
July 2020

Experimental Exposure Assessment of Ionizable Organic Chemicals in Cell-Based Bioassays.

Chem Res Toxicol 2020 07 19;33(7):1845-1854. Epub 2020 May 19.

Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.

View Article and Find Full Text PDF
July 2020

Cellular Metabolism in High-Throughput Reporter Gene Assays and Implications for the Quantitative - Extrapolation.

Chem Res Toxicol 2020 07 13;33(7):1770-1779. Epub 2020 Apr 13.

Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.

View Article and Find Full Text PDF
July 2020

Bioavailability of hydrophobic organic chemicals on an in vitro metabolic transformation using rat liver S9 fraction.

Toxicol In Vitro 2020 Aug 26;66:104835. Epub 2020 Mar 26.

Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, Hölderlinstr. 12, DE-72074 Tübingen, Germany.

View Article and Find Full Text PDF
August 2020

Influence of Co-Dosed Lipids from Biota Extracts on the Availability of Chemicals in In Vitro Cell-Based Bioassays.

Environ Sci Technol 2020 04 16;54(7):4240-4247. Epub 2020 Mar 16.

Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.

View Article and Find Full Text PDF
April 2020

Tracking complex mixtures of chemicals in our changing environment.

Science 2020 01;367(6476):388-392

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4367 Belvaux, Luxembourg.

View Article and Find Full Text PDF
January 2020

Experimental Validation of Mass Balance Models for in Vitro Cell-Based Bioassays.

Environ Sci Technol 2020 01 6;54(2):1120-1127. Epub 2020 Jan 6.

Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.

View Article and Find Full Text PDF
January 2020

Global Transcriptional Analysis of Nontransformed Human Intestinal Epithelial Cells (FHs 74 Int) after Exposure to Selected Drinking Water Disinfection By-Products.

Environ Health Perspect 2019 11 22;127(11):117006. Epub 2019 Nov 22.

Australian Rivers Institute, School of Environment and Science, Griffith University, Gold Coast, Queensland, Australia.

View Article and Find Full Text PDF
November 2019

Effect-Directed Analysis of Progestogens and Glucocorticoids at Trace Concentrations in River Water.

Environ Toxicol Chem 2020 01 30;39(1):189-199. Epub 2019 Nov 30.

Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.

View Article and Find Full Text PDF
January 2020

How To Improve the Dosing of Chemicals in High-Throughput Mammalian Cell Assays.

Chem Res Toxicol 2019 08 2;32(8):1462-1468. Epub 2019 Aug 2.

Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.

View Article and Find Full Text PDF
August 2019

Baseline Toxicity and Volatility Cutoff in Reporter Gene Assays Used for High-Throughput Screening.

Chem Res Toxicol 2019 08 2;32(8):1646-1655. Epub 2019 Aug 2.

Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , DE-04318 Leipzig , Germany.

View Article and Find Full Text PDF
August 2019

Effects of Leachates from UV-Weathered Microplastic in Cell-Based Bioassays.

Environ Sci Technol 2019 Aug 11;53(15):9214-9223. Epub 2019 Jul 11.

Department of Bioanalytical Ecotoxicology and Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstraße 15 , DE-04318 Leipzig , Germany.

View Article and Find Full Text PDF
August 2019

Quantification of freely dissolved effect concentrations in in vitro cell-based bioassays.

Arch Toxicol 2019 08 22;93(8):2295-2305. Epub 2019 Jun 22.

Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.

View Article and Find Full Text PDF
August 2019