Publications by authors named "Beata G Vertessy"

102Publications

Identification of a nuclear localization signal in the Plasmodium falciparum CTP: phosphocholine cytidylyltransferase enzyme.

Authors:
Richard Izrael Lívia Marton Gergely N Nagy Hajnalka L Pálinkás Nóra Kucsma Beáta G Vértessy

Sci Rep 2020 11 12;10(1):19739. Epub 2020 Nov 12.

Institute of Enzymology, Research Centre for Natural Sciences, 1117, Budapest, Hungary.

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November 2020

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.

Authors:
László Petri Péter Ábrányi-Balogh Imre Tímea Gyula Pálfy András Perczel Damijan Knez Martina Hrast Martina Gobec Izidor Sosič Kinga Nyíri Beáta G Vértessy Niklas Jänsch Charlotte Desczyk Franz-Josef Meyer-Almes Iza Ogris Simona Golič Grdadolnik Luca Giacinto Iacovino Claudia Binda Stanislav Gobec György M Keserű

Chembiochem 2020 Oct 8. Epub 2020 Oct 8.

Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Magyar tudósok krt 2, 1117, Budapest, Hungary.

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October 2020

Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments.

Authors:
Hajnalka L Pálinkás Angéla Békési Gergely Róna Lőrinc Pongor Gábor Papp Gergely Tihanyi Eszter Holub Ádám Póti Carolina Gemma Simak Ali Michael J Morten Eli Rothenberg Michele Pagano Dávid Szűts Balázs Győrffy Beáta G Vértessy

Elife 2020 09 21;9. Epub 2020 Sep 21.

Genome Metabolism Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.

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September 2020

Rapid and quantitative antimalarial drug efficacy testing via the magneto-optical detection of hemozoin.

Authors:
Petra Molnár Ágnes Orbán Richard Izrael Réka Babai Lívia Marton Ádám Butykai Stephan Karl Beáta G Vértessy István Kézsmárki

Sci Rep 2020 08 20;10(1):14025. Epub 2020 Aug 20.

Malaria Research Laboratory, Institute of Enzymology, Research Centre for Natural Sciences, Budapest, 1117, Hungary.

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August 2020

Structure-based inhibitor design of mutant RAS proteins-a paradigm shift.

Authors:
Kinga Nyíri Gergely Koppány Beáta G Vértessy

Cancer Metastasis Rev 2020 Dec;39(4):1091-1105

Department of Applied Biotechnology and Food Sciences, Budapest University of Technology and Economics, Budapest, 1111, Hungary.

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December 2020

Unshielding Multidrug Resistant Cancer through Selective Iron Depletion of P-Glycoprotein-Expressing Cells.

Authors:
Mihály Cserepes Dóra Türk Szilárd Tóth Veronika F S Pape Anikó Gaál Melinda Gera Judit E Szabó Nóra Kucsma György Várady Beáta G Vértessy Christina Streli Pál T Szabó Jozsef Tovari Norbert Szoboszlai Gergely Szakács

Cancer Res 2020 02 30;80(4):663-674. Epub 2019 Dec 30.

Institute of Enzymology, Research Centre of Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary.

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February 2020

[Allele-specific inhibitors of mutant KRAS are in the focus of RASopathy consortium].

Authors:
Kinga Nyíri Gergely Koppány Gyula Pálfy István Vida Szilárd Tóth Zoltán Orgován Ivan Ranđelović Marcell Baranyi Eszter Molnár Miklós György Keserû József Tóvári András Perczel Beáta G Vértessy József Tímár

Magy Onkol 2019 12 25;63(4):310-323. Epub 2019 Nov 25.

II. Sz. Patológiai Intézet, Semmelweis Egyetem, Budapest, Hungary.

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December 2019

Beyond Chelation: EDTA Tightly Binds Taq DNA Polymerase, MutT and dUTPase and Directly Inhibits dNTPase Activity.

Authors:
Anna Lopata Balázs Jójárt Éva V Surányi Enikő Takács László Bezúr Ibolya Leveles Ábris Á Bendes Béla Viskolcz Beáta G Vértessy Judit Tóth

Biomolecules 2019 10 17;9(10). Epub 2019 Oct 17.

Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 1113 Budapest, Hungary.

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October 2019

Highly Sensitive and Rapid Characterization of the Development of Synchronized Blood Stage Malaria Parasites Via Magneto-Optical Hemozoin Quantification.

Authors:
Mária Pukáncsik Petra Molnár Ágnes Orbán Ádám Butykai Lívia Marton István Kézsmárki Beáta G Vértessy Mohd Kamil Amanah Abraham Ahmed S I Aly

Biomolecules 2019 10 7;9(10). Epub 2019 Oct 7.

Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul 34093, Turkey.

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October 2019

HDX and Native Mass Spectrometry Reveals the Different Structural Basis for Interaction of the Staphylococcal Pathogenicity Island Repressor Stl with Dimeric and Trimeric Phage dUTPases.

Authors:
Kinga Nyíri Matthew J Harris Judit Matejka Olivér Ozohanics Károly Vékey Antoni J Borysik Beáta G Vértessy

Biomolecules 2019 09 14;9(9). Epub 2019 Sep 14.

Department of Applied Biotechnology and Food Sciences, Budapest University of Technology and Economics, 1111 Budapest, Hungary.

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September 2019

The Role of a Key Amino Acid Position in Species-Specific Proteinaceous dUTPase Inhibition.

Authors:
András Benedek Fanni Temesváry-Kis Tamjidmaa Khatanbaatar Ibolya Leveles Éva Viola Surányi Judit Eszter Szabó Lívius Wunderlich Beáta G Vértessy

Biomolecules 2019 06 6;9(6). Epub 2019 Jun 6.

Budapest University of Technology and Economics, Department of Applied Biotechnology and Food Science, H -1111 Budapest, Szent Gellért tér 4, Hungary.

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June 2019

Evaluation of critical design parameters for RT-qPCR-based analysis of multiple dUTPase isoform genes in mice.

Authors:
Gergely A Rácz Nikolett Nagy Zoltán Gál Tímea Pintér László Hiripi Beáta G Vértessy

FEBS Open Bio 2019 06 29;9(6):1153-1170. Epub 2019 May 29.

Institute of Enzymology, RCNS, Hungarian Academy of Sciences, Budapest, Hungary.

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June 2019

CRISPR/Cas9-Mediated Knock-Out of dUTPase in Mice Leads to Early Embryonic Lethality.

Authors:
Hajnalka Laura Pálinkás Gergely Attila Rácz Zoltán Gál Orsolya Ivett Hoffmann Gergely Tihanyi Gergely Róna Elen Gócza László Hiripi Beáta G Vértessy

Biomolecules 2019 04 4;9(4). Epub 2019 Apr 4.

Institute of Enzymology, RCNS, Hungarian Academy of Sciences, H-1117 Budapest, Hungary.

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April 2019

Mass spectrometry-based analysis of macromolecular complexes of uracil-DNA glycosylase and its inhibitor reveals specific variations due to naturally occurring mutations.

Authors:
Veronika Papp-Kádár Zoltán Balázs Károly Vékey Olivér Ozohanics Beáta G Vértessy

FEBS Open Bio 2019 03 9;9(3):420-427. Epub 2019 Feb 9.

Hungarian Academy of Sciences Research Centre for Natural Sciences Institute of Enzymology Budapest Hungary.

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March 2019

Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.

Authors:
Balázs Merő László Radnai Gergő Gógl Orsolya Tőke Ibolya Leveles Kitti Koprivanacz Bálint Szeder Metta Dülk Gyöngyi Kudlik Virág Vas Anna Cserkaszky Szabolcs Sipeki László Nyitray Beáta G Vértessy László Buday

J Biol Chem 2019 03 18;294(12):4608-4620. Epub 2019 Jan 18.

From the Institute of Enzymology and

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March 2019

Uracil moieties in genomic DNA.

Authors:
Petra Molnár Lívia Marton Richard Izrael Hajnalka L Pálinkás Beáta G Vértessy

FEBS Open Bio 2018 Nov 29;8(11):1763-1772. Epub 2018 Sep 29.

Research Centre for Natural Sciences Institute of Enzymology BME-MTA Malaria Research Laboratory Hungarian Academy of Sciences Budapest Hungary.

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November 2018

The role of enzyme adsorption in the enzymatic degradation of an aliphatic polyester.

Authors:
Péter Polyák Eszter Urbán Gergely N Nagy Beáta G Vértessy Béla Pukánszky

Enzyme Microb Technol 2019 Jan 21;120:110-116. Epub 2018 Oct 21.

Laboratory of Plastics and Rubber Technology, Department of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, H-1521 Budapest, P.O. Box 91, Hungary; Polymer Physics Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, H-1519 Budapest, P.O. Box 286, Hungary. Electronic address:

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January 2019

Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis.

Authors:
Ewelina Guca Gergely N Nagy Fanni Hajdú Lívia Marton Richard Izrael François Hoh Yinshan Yang Henri Vial Beata G Vértessy Jean-François Guichou Rachel Cerdan

Sci Rep 2018 07 25;8(1):11215. Epub 2018 Jul 25.

Dynamique des Interactions Membranaires Normales et Pathologiques, UMR 5235, CNRS, Université de Montpellier, Montpellier, France.

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July 2018

Heterologous expression of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum rescues Chinese Hamster Ovary cells deficient in the Kennedy phosphatidylcholine biosynthesis pathway.

Authors:
Lívia Marton Fanni Hajdú Gergely N Nagy Nóra Kucsma Gergely Szakács Beáta G Vértessy

Sci Rep 2018 06 12;8(1):8932. Epub 2018 Jun 12.

Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, 1117, Hungary.

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June 2018

Exploiting a Phage-Bacterium Interaction System as a Molecular Switch to Decipher Macromolecular Interactions in the Living Cell.

Authors:
Éva Viola Surányi Rita Hírmondó Kinga Nyíri Szilvia Tarjányi Bianka Kőhegyi Judit Tóth Beáta G Vértessy

Viruses 2018 04 1;10(4). Epub 2018 Apr 1.

Department of Applied Biotechnology and Food Sciences, Budapest University of Technology and Economics, H-1111 Budapest, Hungary.

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April 2018