Publications by authors named "Beat Lutz"

100Publications

Quantification of the Cannabinoid Type 1 Receptor Availability in the Mouse Brain.

Front Neuroanat 2020 20;14:593793. Epub 2020 Nov 20.

Department of Nuclear Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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November 2020

Cell type-specific genetic reconstitution of CB1 receptor subsets to assess their role in exploratory behaviour, sociability and memory.

Eur J Neurosci 2020 Nov 30. Epub 2020 Nov 30.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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November 2020

Neurobiology of cannabinoid receptor signaling
.

Authors:
Beat Lutz

Dialogues Clin Neurosci 2020 Sep;22(3):207-222

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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September 2020

Differential glutamatergic and GABAergic contributions to the tetrad effects of Δ-tetrahydrocannabinol revealed by cell-type-specific reconstitution of the CB1 receptor.

Neuropharmacology 2020 11 26;179:108287. Epub 2020 Aug 26.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany. Electronic address:

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November 2020

The endocannabinoid 2-arachidonoylglycerol inhibits endothelial function and repair.

Int J Cardiol 2021 Jan 15;323:243-250. Epub 2020 Aug 15.

Department of Internal Medicine II Cardiology, Pneumology, Angiology, University Hospital Bonn, Venusberg-Campus 1, Bonn 53127, Germany.

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January 2021

Influence of Cannabinoid Receptor Deficiency on Parameters Involved in Blood Glucose Regulation in Mice.

Int J Mol Sci 2020 Apr 30;21(9). Epub 2020 Apr 30.

Institute of Anatomy and Cell Biology, Medical Faculty of Martin Luther, University Halle-Wittenberg, 06108 Halle (Saale), Germany.

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April 2020

Cerebrospinal fluid endocannabinoid levels in Gilles de la Tourette syndrome.

Neuropsychopharmacology 2020 07 9;45(8):1323-1329. Epub 2020 Apr 9.

Department of Neurology, Hannover Medical School, Hannover, Germany.

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July 2020

Sexually Dimorphic Behavioral Profile in a Transgenic Model Enabling Targeted Recombination in Active Neurons in Response to Ketamine and (2R,6R)-Hydroxynorketamine Administration.

Int J Mol Sci 2020 Mar 20;21(6). Epub 2020 Mar 20.

Laboratory of Translational Psychiatry and Focus Program Translational Neurosciences, Johannes Gutenberg University Medical Center Mainz, 55128 Mainz, Germany.

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March 2020

Endocannabinoid LTD in Accumbal D1 Neurons Mediates Reward-Seeking Behavior.

iScience 2020 Mar 28;23(3):100951. Epub 2020 Feb 28.

Institute of Psychopharmacology, Central Institute of Mental Health, Heidelberg University, Medical Faculty Mannheim, 68159 Mannheim, Germany. Electronic address:

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March 2020

Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure.

Neuropsychopharmacology 2020 04 26;45(5):877-886. Epub 2020 Jan 26.

Department of Biochemistry and Molecular Biology, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, 28040, Madrid, Spain.

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April 2020

Endocannabinoid 2-arachidonoylglycerol is elevated in the coronary circulation during acute coronary syndrome.

PLoS One 2019 30;14(12):e0227142. Epub 2019 Dec 30.

Department of Internal Medicine II Cardiology, Pneumology, Angiology, University Hospital Bonn, Bonn, Germany.

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April 2020

Altered brain levels of arachidonic acid-derived inflammatory eicosanoids in a rodent model of anorexia nervosa.

Biochim Biophys Acta Mol Cell Biol Lipids 2020 04 26;1865(4):158578. Epub 2019 Nov 26.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany.

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April 2020

Adipocyte cannabinoid CB1 receptor deficiency alleviates high fat diet-induced memory deficit, depressive-like behavior, neuroinflammation and impairment in adult neurogenesis.

Psychoneuroendocrinology 2019 12 23;110:104418. Epub 2019 Aug 23.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany; German Resilience Center (DRZ), Mainz, Germany. Electronic address:

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December 2019

Erratum to "Oleoylethanolamide restores alcohol-induced inhibition of neuronal proliferation and microglial activity in striatum" [Neuropharmacology 146 (2019) 184-197].

Neuropharmacology 2019 Dec 17;160:107708. Epub 2019 Jul 17.

Instituto de Investigación Biomédica de Málaga (IBIMA), UGC Salud Mental, Universidad de Málaga, Hospital Universitario Regional de Málaga, Málaga, Spain. Electronic address:

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December 2019

Broad Lipidomic and Transcriptional Changes of Prophylactic PEA Administration in Adult Mice.

Front Neurosci 2019 11;13:527. Epub 2019 Jun 11.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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June 2019

Salivary endocannabinoids as mediators in the relationship between omega-6 and omega-3 fatty acid ratio intake from highly-processed foods and anthropometric markers of health in women.

Int J Food Sci Nutr 2020 Mar 25;71(2):235-241. Epub 2019 Jun 25.

Department of Neurobehavioral Genetics, Institute of Psychobiology, University of Trier, Trier, Germany.

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March 2020

Cell type specific impact of cannabinoid receptor signaling in somatosensory barrel map formation in mice.

J Comp Neurol 2020 01 1;528(1):3-13. Epub 2019 Jul 1.

Institute of Physiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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January 2020

Myocardial maladaptation to pressure overload in CB2 receptor-deficient mice.

J Mol Cell Cardiol 2019 08 7;133:86-98. Epub 2019 Jun 7.

Department of Cardiac Surgery, University Clinical Centre Bonn, Germany. Electronic address:

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August 2019

Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation.

Cancer Gene Ther 2020 05 9;27(5):294-300. Epub 2019 May 9.

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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May 2020

Prominent Postsynaptic and Dendritic Exocytosis of Endogenous BDNF Vesicles in BDNF-GFP Knock-in Mice.

Mol Neurobiol 2019 Oct 30;56(10):6833-6855. Epub 2019 Mar 30.

Institute of Physiology, Medical Faculty, Otto-von-Guericke University, Leipziger Str. 44, D-39120, Magdeburg, Germany.

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October 2019

Multiple endocannabinoid-mediated mechanisms in the regulation of energy homeostasis in brain and peripheral tissues.

Cell Mol Life Sci 2019 Apr 1;76(7):1341-1363. Epub 2019 Jan 1.

German Resilience Center (DRZ) and Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Duesbergweg 5, 55128, Mainz, Germany.

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April 2019

Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses.

Neuropsychopharmacology 2019 07 15;44(8):1377-1388. Epub 2018 Nov 15.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Duesbergweg 6, 55128, Mainz, Germany.

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July 2019

Oleoylethanolamide restores alcohol-induced inhibition of neuronal proliferation and microglial activity in striatum.

Neuropharmacology 2019 03 26;146:184-197. Epub 2018 Nov 26.

Instituto de Investigación Biomédica de Málaga (IBIMA), UGC Salud Mental, Universidad de Málaga, Hospital Universitario Regional de Málaga, Málaga, Spain. Electronic address:

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March 2019

Plasma Parameters of the Endocannabinoid System Are Unaltered in Fibromyalgia.

Psychother Psychosom 2018 26;87(6):377-379. Epub 2018 Sep 26.

Department of General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.

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December 2018

The F238L Point Mutation in the Cannabinoid Type 1 Receptor Enhances Basal Endocytosis via Lipid Rafts.

Front Mol Neurosci 2018 5;11:230. Epub 2018 Jul 5.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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July 2018

Elevated levels of 2-arachidonoylglycerol promote atherogenesis in ApoE-/- mice.

PLoS One 2018 29;13(5):e0197751. Epub 2018 May 29.

Department of Internal Medicine II Cardiology, Pneumology, Angiology, University Hospital Bonn, Bonn, Germany.

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December 2018

Antiepileptogenic Effect of Subchronic Palmitoylethanolamide Treatment in a Mouse Model of Acute Epilepsy.

Front Mol Neurosci 2018 14;11:67. Epub 2018 Mar 14.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany.

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March 2018

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.

Dev Cell 2018 03 15;44(6):709-724.e6. Epub 2018 Mar 15.

Center for Neuropathology, Ludwig-Maximilians-University, 81377 Munich, Germany; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, N63 (HPI), Hamburg 20251, Germany; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

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March 2018

Age-related regulation of bone formation by the sympathetic cannabinoid CB1 receptor.

Bone 2018 03 20;108:34-42. Epub 2017 Dec 20.

Obesity and Metabolism Laboratory, The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel. Electronic address:

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March 2018

Pharmacokinetics of the cannabinoid receptor ligand [ F]MK-9470 in the rat brain - Evaluation of models using microPET.

Med Phys 2018 Feb 9;45(2):725-734. Epub 2018 Jan 9.

Department of Nuclear Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.

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February 2018

Simultaneous lipidomic and transcriptomic profiling in mouse brain punches of acute epileptic seizure model compared to controls.

J Lipid Res 2018 02 5;59(2):283-297. Epub 2017 Dec 5.

University Medical Center of Johannes Gutenberg University Mainz, Institute of Physiological Chemistry, 55128 Mainz, Germany; and

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February 2018

Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.

Hum Mol Genet 2018 01;27(1):190-198

Mammalian Genetics Unit, Medical Research Council, Harwell Institute, Oxfordshire OX11 0RD, UK.

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January 2018

Building Bridges through Science.

Authors:
Thomas Lissek Michelle Adams John Adelman Ehud Ahissar Mohammed Akaaboune Huda Akil Mustafa al'Absi Fazal Arain Juan Carlos Arango-Lasprilla Deniz Atasoy Jesus Avila Ashraf Badawi Hilmar Bading Abdul Mannan Baig Jimena Baleriola Carlos Belmonte Ilaria Bertocchi Heinrich Betz Colin Blakemore Olaf Blanke Philipp Boehm-Sturm Tobias Bonhoeffer Paolo Bonifazi Nils Brose Patrizia Campolongo Tansu Celikel Cathy C Chang Ta-Yuan Chang Ami Citri Hollis T Cline Jesus M Cortes Kathleen Cullen Kellie Dean José M Delgado-Garcia Mathieu Desroches John F Disterhoft John E Dowling Andreas Draguhn Sherif F El-Khamisy Abdeljabbar El Manira S Ather Enam Juan M Encinas Asier Erramuzpe José A Esteban Isabel Fariñas Edmond Fischer Izumi Fukunaga Iñigo Gabilondo Detlev Ganten Albert Gidon Juan Carlos Gomez-Esteban Paul Greengard Valery Grinevich Agnés Gruart Roger Guillemin Ahmad R Hariri Bassem Hassan Michael Häusser Yasunori Hayashi Natasha K Hussain Adnan Abdul Jabbar Mohamed Jaber Reinhardt Jahn Essam Mohammed Janahi Mohamed Kabbaj Helmut Kettenmann Merel Kindt Shira Knafo Georg Köhr Shoji Komai Harm Krugers Bernd Kuhn Nouria Lakhdar Ghazal Matthew E Larkum Mickey London Beat Lutz Carlos Matute Luis Martinez-Millan Mouna Maroun James McGaugh Ahmed A Moustafa Anwar Nasim Klaus-Armin Nave Erwin Neher Karoly Nikolich Tiago Outeiro Lucy M Palmer Olga Penagarikano Isabel Perez-Otano Donald W Pfaff Bruno Poucet Atta-Ur Rahman Pedro Ramos-Cabrer Ali Rashidy-Pour Richard J Roberts Serafim Rodrigues Joshua R Sanes Andreas T Schaefer Menahem Segal Idan Segev Saad Shafqat Nikhat Ahmed Siddiqui Hermona Soreq Eduardo Soriano-García Rainer Spanagel Rolf Sprengel Greg Stuart Thomas C Südhof Jan Tønnesen Mario Treviño Basim M Uthman J Craig Venter Alexei Verkhratsky Craig Weiss Torsten N Wiesel Emre Yaksi Ofer Yizhar Larry J Young Paul Young Nasser H Zawia José L Zugaza Mazahir T Hasan

Neuron 2017 Nov;96(4):730-735

Achucarro Basque Center for Neuroscience, 48940 Leioa, Spain. Electronic address:

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November 2017

Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse.

J Neurochem 2017 08 18;142(4):521-533. Epub 2017 Jul 18.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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August 2017

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

Authors:
Rhea van den Bruck Patrick P Weil Thomas Ziegenhals Philipp Schreiner Stefan Juranek Daniel Gödde Silvia Vogel Frauke Schuster Valerie Orth Johannes Dörner Daniel Pembaur Meike Röper Stefan Störkel Hubert Zirngibl Stefan Wirth Andreas C W Jenke Jan Postberg Nikolas Boy Jana Heringer Gisela Haege Esther M Glahn Georg F Hoffmann Sven F Garbade Peter Burgard Stefan Kölker Cho-Ming Chao Faady Yahya Alena Moiseenko Amit Shrestha Negah Ahmadvand Jennifer Quantius Jochen Wilhelm Elie El-Agha Klaus-Peter Zimmer Saverio Bellusci Christian Staufner Stefan Kölker Holger Prokisch Georg F Hoffmann Stephan Seeliger Matthias Müller Andreas Hippe Henrik Steinkraus Roland Wauer Burkhard Lachmann Sigrun R Hofmann Christian M Hedrich Jakob Zierk Farhad Arzideh Rainer Haeckel Wolfgang Rascher Manfred Rauh Markus Metzler Sebastian Thieme Joanna Bandoła Cornelia Richter Martin Ryser Arshad Jamal Michelle P Ashton Malte von Bonin Matthias Kuhn Christian M Hedrich Ezio Bonifacio Reinhard Berner Sebastian Brenner Johanna Hammersen Cristina Has Nora Naumann-Bartsch Daniel Stachel Dimitra Kiritsi Stephan Söder Mathilde Tardieu Markus Metzler Leena Bruckner-Tuderman Holm Schneider F Bohne D Langer R Cencic T Eggermann U Zechner J Pelletier F Zepp T Enklaar D Prawitt Martin Pech Markus Weckmann Femke-Anouska Heinsen Andre Franke Christine Happle Anna-Maria Dittrich Gesine Hansen Oliver Fuchs Erika von Mutius Brian G Oliver Matthias V Kopp Claudia Paret Alexandra Russo Johanna Theruvath Bettina Keller Khalifa El Malki Nadine Lehmann Arthur Wingerter Marie A Neu Gerhold-Ay Aslihan Wolfgang Wagner Clemens Sommer Torsten Pietsch Larissa Seidmann Jörg Faber Felix Schreiner Merle Ackermann Michael Michalik Eva Rother Andras Bilkei-Gorzo Ildiko Racz Laura Bindila Beat Lutz Jörg Dötsch Andreas Zimmer Joachim Woelfle Hendrik S Fischer Tim L Ullrich Christoph Bührer Christoph Czernik Gerd Schmalisch Robert Stein Sigrun R Hofmann Judith Hagenbuchner Ursula Kiechl-Kohlendorfer Petra Obexer Michael J Ausserlechner Niki T Loges Adrien Tobias Frommer Julia Wallmeier Heymut Omran Soner Öner-Sieben Martina Gimpfl Jan Rozman Martin Irmler Johannes Beckers Martin Hrabe De Angelis Adelbert Roscher Eckhard Wolf Regina Ensenauer Karolina Nemes Michael Frühwald Martin Hasselblatt Reiner Siebert Uwe Kordes Marcel Kool Haicui Wang Holly Hardy Osama Refai Katy E S Barwick Holly H Zimmerman Joachim Weis Emma L Baple Andrew H Crosby Sebahattin Cirak C Hellmuth O Uhl M Standl J Heinrich E Thiering B Koletzko Lena Blümel Kornelius Kerl Daniel Picard Michael C Frühwald Max C Liebau Guido Reifenberger Arndt Borkhardt Martin Hasselblatt Marc Remke D Tews M Wabitsch P Fischer-Posovszky Mike-Andrew Westhoff Lisa Nonnenmacher Julia Langhans Lukas Schneele Nancy Trenkler Klaus-Michael Debatin

Mol Cell Pediatr 2017 May;4(Suppl 1)

Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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May 2017

Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons.

Brain Struct Funct 2017 Nov 9;222(8):3431-3452. Epub 2017 Apr 9.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, 55128, Mainz, Germany.

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November 2017

Electroconvulsive therapy enhances endocannabinoids in the cerebrospinal fluid of patients with major depression: a preliminary prospective study.

Eur Arch Psychiatry Clin Neurosci 2017 Dec 24;267(8):781-786. Epub 2017 Mar 24.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, J5, 68159, Mannheim, Germany.

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December 2017

Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry.

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Feb 15;1862(2):255-267. Epub 2016 Nov 15.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Duesbergweg 6, 55128 Mainz, Germany. Electronic address:

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February 2017

Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring.

Front Behav Neurosci 2016 1;10:208. Epub 2016 Nov 1.

Departamento de Psicobiología, Facultad de Psicología, Universidad Complutense de MadridMadrid, Spain; Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario de Málaga, Universidad de MálagaMálaga, Spain.

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November 2016

Adverse Social Experiences in Adolescent Rats Result in Enduring Effects on Social Competence, Pain Sensitivity and Endocannabinoid Signaling.

Front Behav Neurosci 2016 20;10:203. Epub 2016 Oct 20.

Research Group Developmental Neuropsychopharmacology, Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, University of HeidelbergMannheim, Germany; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, University of HeidelbergMannheim, Germany.

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October 2016

Chronic stress leads to epigenetic dysregulation in the neuropeptide-Y and cannabinoid CB1 receptor genes in the mouse cingulate cortex.

Neuropharmacology 2017 02 11;113(Pt A):301-313. Epub 2016 Oct 11.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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February 2017

Restricted vs. unrestricted wheel running in mice: Effects on brain, behavior and endocannabinoids.

Horm Behav 2016 11 20;86:45-54. Epub 2016 Sep 20.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, University Medicine Mannheim, University of Heidelberg, 68159 Mannheim, Germany; Institute for Sex Research and Forensic Psychiatry, Center of Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

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November 2016

ESC-Derived BDNF-Overexpressing Neural Progenitors Differentially Promote Recovery in Huntington's Disease Models by Enhanced Striatal Differentiation.

Stem Cell Reports 2016 10 29;7(4):693-706. Epub 2016 Sep 29.

Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany. Electronic address:

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October 2016

Cell Type-Specific Tandem Affinity Purification of the Mouse Hippocampal CB1 Receptor-Associated Proteome.

J Proteome Res 2016 10 19;15(10):3585-3601. Epub 2016 Sep 19.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg-University Mainz , Duesbergweg 6, 55128 Mainz, Germany.

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October 2016

Peripheral and central CB1 cannabinoid receptors control stress-induced impairment of memory consolidation.

Proc Natl Acad Sci U S A 2016 08 15;113(35):9904-9. Epub 2016 Aug 15.

Laboratory of Neuropharmacology-NeuroPhar, Department of Experimental and Health Sciences, University Pompeu Fabra, 08003 Barcelona, Spain;

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August 2016

Extraction and Simultaneous Quantification of Endocannabinoids and Endocannabinoid-Like Lipids in Biological Tissues.

Methods Mol Biol 2016 ;1412:9-18

Institute for Physiological Chemistry, University Medical Center, Duesbergweg 6, 55128, Mainz, Germany.

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December 2017

Lack of hippocampal CB1 receptor desensitization by Δ(9)-tetrahydrocannabinol in aged mice and by low doses of JZL 184.

Naunyn Schmiedebergs Arch Pharmacol 2016 Jun 17;389(6):603-12. Epub 2016 Mar 17.

Institute of Pharmacology and Toxicology, Medical Faculty, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany.

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June 2016

Cannabinoid Control of Learning and Memory through HCN Channels.

Neuron 2016 Mar 18;89(5):1059-73. Epub 2016 Feb 18.

Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.

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March 2016

Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons.

Neural Plast 2016 10;2016:4145708. Epub 2016 Jan 10.

Institute of Physiology, Medical Faculty, Otto-von-Guericke-University, 39120 Magdeburg, Germany; Center of Behavioral Brain Sciences (CBBS), 39106 Magdeburg, Germany.

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December 2016

PSA-NCAM positive neural progenitors stably expressing BDNF promote functional recovery in a mouse model of spinal cord injury.

Stem Cell Res Ther 2016 Jan 13;7:11. Epub 2016 Jan 13.

Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany.

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January 2016

Evaluation of MRI and cannabinoid type 1 receptor PET templates constructed using DARTEL for spatial normalization of rat brains.

Med Phys 2015 Dec;42(12):6875-84

Department of Nuclear Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstraße 1, Mainz 55131, Germany.

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December 2015

The endocannabinoid system in guarding against fear, anxiety and stress.

Nat Rev Neurosci 2015 12;16(12):705-18

Department of Pharmacology and Toxicology, Neuroscience Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA.

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December 2015

The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons.

PLoS Biol 2015 Oct 23;13(10):e1002286. Epub 2015 Oct 23.

Pharmacology Institute, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.

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October 2015

Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB1 receptors on developing cortical neurons.

Proc Natl Acad Sci U S A 2015 Nov 12;112(44):13693-8. Epub 2015 Oct 12.

Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 28049 Madrid, Spain; Instituto de Investigación Sanitaria Ramón y Cajal (IRYCIS), 28034 Madrid, Spain; Department of Biochemistry and Molecular Biology I, Complutense University, 28040 Madrid, Spain;

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November 2015

A runner's high depends on cannabinoid receptors in mice.

Proc Natl Acad Sci U S A 2015 Oct 5;112(42):13105-8. Epub 2015 Oct 5.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, University Medicine Mannheim, University of Heidelberg, 68159 Mannheim, Germany;

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October 2015

Cannabinoid type-1 receptor signaling in central serotonergic neurons regulates anxiety-like behavior and sociability.

Front Behav Neurosci 2015 3;9:235. Epub 2015 Sep 3.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Germany.

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September 2015

Age-related changes in the endocannabinoid system in the mouse hippocampus.

Mech Ageing Dev 2015 Sep 13;150:55-64. Epub 2015 Aug 13.

Institute of Molecular Psychiatry, Medical Faculty, University of Bonn, 53127 Bonn, Germany. Electronic address:

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September 2015

Impaired 2-AG Signaling in Hippocampal Glutamatergic Neurons: Aggravation of Anxiety-Like Behavior and Unaltered Seizure Susceptibility.

Int J Neuropsychopharmacol 2015 Aug 1;19(2). Epub 2015 Aug 1.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany (Dr Guggenhuber, Dr Bindila, Dr Leschik, Dr Lomazzo, Dr Remmers, Ms Zimmermann, Ms Lerner, Dr Klugmann, and Dr Lutz); Institute of Physiology I (Neurophysiology), Westfaelische Wilhelms-University, Muenster, Germany (Drs Romo-Parra and Pape); Translational Neuroscience Facility, Department of Physiology, School of Medical Sciences, University of New South Wales, UNSW Kensington Campus, Sydney, NSW, Australia (Dr Klugmann).

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August 2015

Anxiety, Stress, and Fear Response in Mice With Reduced Endocannabinoid Levels.

Biol Psychiatry 2016 05 14;79(10):858-868. Epub 2015 Apr 14.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.. Electronic address:

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May 2016

Endocannabinoid Levels in Newborns in Relation to the Mode of Delivery.

Am J Perinatol 2015 Oct 27;32(12):1145-50. Epub 2015 Apr 27.

Clinic of Neonatology, University Medical Center Mannheim, Mannheim, Germany.

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October 2015

Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context.

Front Cell Neurosci 2015 27;9:98. Epub 2015 Mar 27.

UGC Salud Mental, Instituto de Investigación Biomédica (IBIMA), Universidad de Málaga-Hospital Universitario Regional de Málaga Málaga, Spain ; CIBER OBN, Instituto de Salud Carlos III Madrid, Spain.

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April 2015

Age differences in the role of the cannabinoid type 1 receptor on glutamatergic neurons in habituation and spatial memory acquisition.

Life Sci 2015 Oct 2;138:57-63. Epub 2015 Mar 2.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany. Electronic address:

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October 2015

Cannabinoid CB1 receptor calibrates excitatory synaptic balance in the mouse hippocampus.

J Neurosci 2015 Mar;35(9):3842-50

Zoological Institute, Division Cellular Neurobiology, 38106 Braunschweig, Germany, and AG NIND, HZI, D-38124 Braunschweig, Germany

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March 2015

Therapeutic potential of inhibitors of endocannabinoid degradation for the treatment of stress-related hyperalgesia in an animal model of chronic pain.

Neuropsychopharmacology 2015 Jan 6;40(2):488-501. Epub 2014 Aug 6.

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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January 2015

Studying mitochondrial CB1 receptors: Yes we can.

Mol Metab 2014 Jul 12;3(4):339. Epub 2014 Apr 12.

INSERM U862, NeuroCentre Magendie, 33077 Bordeaux, France ; University of Bordeaux, 33077 Bordeaux, France.

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July 2014