Bastian Schilling

Bastian Schilling

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Bastian Schilling

Bastian Schilling

Publications by authors named "Bastian Schilling"

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Superior skin cancer classification by the combination of human and artificial intelligence.

Eur J Cancer 2019 Oct 10;120:114-121. Epub 2019 Sep 10.

National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, Germany; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.07.019DOI Listing
October 2019

Localization of PD-L1 on single cancer cells by iSERS microscopy with Au/Au core/satellite nanoparticles.

J Biophotonics 2019 Oct 12:e201960034. Epub 2019 Oct 12.

Department of Chemistry and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitätsstr. 5, Essen, Germany.

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http://dx.doi.org/10.1002/jbio.201960034DOI Listing
October 2019

Deep neural networks are superior to dermatologists in melanoma image classification.

Eur J Cancer 2019 Sep 8;119:11-17. Epub 2019 Aug 8.

Department of Dermatology, Heidelberg University, Mannheim, Germany; Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2019.05.023DOI Listing
September 2019

Prediction of melanoma evolution in melanocytic nevi via artificial intelligence: A call for prospective data.

Eur J Cancer 2019 Sep 8;119:30-34. Epub 2019 Aug 8.

Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany; National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 460, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.07.009DOI Listing
September 2019

Chemoirradiated neutrophils and T cells differentially affect immune functions of APCs.

J Leukoc Biol 2019 Aug 10;106(2):481-493. Epub 2019 May 10.

Department of Dermatology, Venereology and Allergology, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1002/JLB.5A0618-242RDOI Listing
August 2019

Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma.

Eur J Cancer 2019 Jul 15;116:207-215. Epub 2019 Jun 15.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.05.015DOI Listing
July 2019

Response to combined ipilimumab and nivolumab after development of a nephrotic syndrome related to PD-1 monotherapy.

J Immunother Cancer 2019 Jul 12;7(1):181. Epub 2019 Jul 12.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Josef-Schneider-Str, 2, 97080, Würzburg, Germany.

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http://dx.doi.org/10.1186/s40425-019-0655-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626404PMC
July 2019

Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task.

Eur J Cancer 2019 May 10;113:47-54. Epub 2019 Apr 10.

National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 460, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2019.04.001DOI Listing
May 2019

Patterns of disease control and survival in patients with melanoma brain metastases undergoing immune-checkpoint blockade.

Eur J Cancer 2018 08 12;99:58-65. Epub 2018 Jun 12.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, 97080 Würzburg, Germany; Department of Dermatology, Venereology and Allergology, University Hospital Essen, University Duisburg-Essen, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.05.012DOI Listing
August 2018

Can checkpoint inhibitor therapy improve response to chemotherapy?

J Cancer Res Clin Oncol 2018 01 24;144(1):183-185. Epub 2017 Nov 24.

Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00432-017-2546-8DOI Listing
January 2018

Coincident Metastatic Melanoma and Merkel Cell Carcinoma with Complete Remission on Treatment with Pembrolizumab.

Acta Derm Venereol 2017 Nov;97(10):1252-1254

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Josef-Schneider-Straße 2, DE-97080 Würzburg, Germany.

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http://dx.doi.org/10.2340/00015555-2757DOI Listing
November 2017

Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitis.

Eur J Cancer 2017 11 19;86:248-256. Epub 2017 Oct 19.

Department of Dermatology, Venereology and Allergology, University Hospital Essen, University Duisburg-Essen, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, 97080 Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.09.019DOI Listing
November 2017

Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris Melanoma.

Invest Ophthalmol Vis Sci 2017 07;58(9):3464-3470

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany 8Dermatopathologie bei Mainz, Nieder-Olm, Germany.

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http://dx.doi.org/10.1167/iovs.17-21838DOI Listing
July 2017

Next-Generation Sequencing to Guide Treatment of Advanced Melanoma.

Am J Clin Dermatol 2017 Jun;18(3):303-310

Department of Dermatology, University Hospital, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Hufelandstr. 55, Essen, 45147, Germany.

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http://dx.doi.org/10.1007/s40257-017-0260-6DOI Listing
June 2017

Molecular features of response to anti-PD-1 therapy.

Chin Clin Oncol 2016 Dec 19;5(6):74. Epub 2016 Jul 19.

Department of Dermatology, Venereology and Allergology, University Hospital, West German Cancer Center, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.21037/cco.2016.06.01DOI Listing
December 2016

Oncogene Status of an Interdigitating Dendritic Cell Sarcoma: Recurrent Mutations in NF1, TP53, and ARID2 Shared With Melanoma.

Am J Surg Pathol 2016 12;40(12):1721-1723

*Department of Dermatology Venerology and Allergology, University Hospital, University of Duisburg-Essen †German Cancer Consortium (DKTK) ‡Zentrum für Pathologie Essen-Mitte Essen, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000746DOI Listing
December 2016

Checkpoint inhibitors in chronic kidney failure and an organ transplant recipient.

Eur J Cancer 2016 11 8;67:66-72. Epub 2016 Sep 8.

Department of Dermatology, Venereology and Allergology, University Hospital, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2016.07.026DOI Listing
November 2016

Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human.

Int J Cancer 2016 Apr 17;138(8):1982-93. Epub 2015 Dec 17.

Molecular Immunology, Helmholtz Centre for Infection Research, HZI, Braunschweig, Germany.

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http://dx.doi.org/10.1002/ijc.29945DOI Listing
April 2016

Oncogene status as a diagnostic tool in ocular and cutaneous melanoma.

Eur J Cancer 2016 Apr 23;57:112-7. Epub 2016 Feb 23.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.01.010DOI Listing
April 2016

Corticosteroids augment BRAF inhibitor vemurafenib induced lymphopenia and risk of infection.

PLoS One 2015 21;10(4):e0124590. Epub 2015 Apr 21.

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124590PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405567PMC
March 2016

Phenotypic characterization and prognostic impact of circulating γδ and αβ T-cells in metastatic malignant melanoma.

Int J Cancer 2016 Feb 18;138(3):698-704. Epub 2015 Sep 18.

Department of Internal Medicine II, University Medical Center, Tübingen, Germany.

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http://doi.wiley.com/10.1002/ijc.29818
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http://dx.doi.org/10.1002/ijc.29818DOI Listing
February 2016

Metastatic Malignant Melanoma With Complete Loss of Differentiation Markers (Undifferentiated/Dedifferentiated Melanoma): Analysis of 14 Patients Emphasizing Phenotypic Plasticity and the Value of Molecular Testing as Surrogate Diagnostic Marker.

Am J Surg Pathol 2016 Feb;40(2):181-91

*Institute of Pathology, University of Erlangen-Nürnberg, Erlangen†Institute of Pathology, Technical University of München, Munich‡Institute of Pathology, Caritas-Krankenhaus, Bad Mergentheim gGmbH, Bad Mergentheim§Institute of Pathology, Klinikum Augsburg, Augsburg∥Institute of Pathology, Sana Klinikum Lichtenberg, Berlin¶Institute of Pathology#Department of Dermatology, University of Duisburg-Essen, Essen**Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany.

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http://pdfs.journals.lww.com/ajsp/2016/02000/Metastatic_Mali
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000527DOI Listing
February 2016

Granulocytic myeloid-derived suppressor cells in peripheral blood of patients with cutaneous melanoma.

Int Immunol 2016 Feb 29;28(2):99. Epub 2015 Dec 29.

Department of Dermatology, University Hospital, West German Cancer Center, University Duisburg-Essen and German Cancer Consortium (DKTK), Essen, Germany

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http://dx.doi.org/10.1093/intimm/dxv077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885221PMC
February 2016

[Editorial].

J Dtsch Dermatol Ges 2016 Jan;14(1):1-2

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http://dx.doi.org/10.1111/ddg.12932DOI Listing
January 2016

Frequent TERT Promoter Mutations in Ocular Surface Squamous Neoplasia.

Invest Ophthalmol Vis Sci 2015 Sep;56(10):5854-61

Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen and the German Cancer Consortium (DKTK), Essen, Germany.

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http://dx.doi.org/10.1167/iovs.15-17469DOI Listing
September 2015

Genetic evolution of T-cell resistance in the course of melanoma progression.

Clin Cancer Res 2014 Dec 7;20(24):6593-604. Epub 2014 Oct 7.

Department of Dermatology, University Hospital Essen, University Duisburg-Essen, Essen, Germany. German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0567DOI Listing
December 2014

TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma.

J Natl Cancer Inst 2014 Sep 13;106(9). Epub 2014 Sep 13.

Department of Dermatology,University Hospital Essen, West German Cancer Center, University Duisburg-Essen, Essen and the German Cancer Consortium (KGG, BS, EL, TS, IM, MS, AS, UH, LZ, DS), Germany; Department of Pathology and Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY (RM); CIBER Enfermedades Raras, Instituto de Salud Carlos III, Barcelona, Spain (JAPB, MP, CC, CB, JM, SP); Department of Dermatology, Hospital Clinic Barcelona, IDIBAPS, Universitat de Barcelona, Barcelona, Spain (CC, JM, SP); Biochemistry and Molecular Genetics Department, Hospital Clinic Barcelona, IDIBAPS, Barcelona, Spain (CB); Integriertes Forschungs- und Behandlungszentrum (IFB) Sepsis und Sepsisfolgen Center for Sepsis Control and Care (CSCC) University Hospital Jena, Jena, Germany (AS).

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http://dx.doi.org/10.1093/jnci/dju246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200061PMC
September 2014

Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells.

Clin Cancer Res 2014 Mar 9;20(6):1601-9. Epub 2013 Dec 9.

Authors' Affiliations: Department of Dermatology, University Medical Center; Department of Internal Medicine II, Section for Transplantation Immunology and Immunohematology, University of Tübingen, Tübingen; German Cancer Research Center (DKFZ); German Cancer Consortium (DKTK), Heidelberg; Department of Dermatology, University Hospital, West German Cancer Center, University Duisburg-Essen, Essen, Germany; Department of Medical Oncology and Immunotherapy, University Hospital of Siena, Istituto Toscano Tumori, Italy; and Skin Cancer Research Group, School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Townsville, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2508DOI Listing
March 2014

Genetic and clinico-pathologic analysis of metastatic uveal melanoma.

Mod Pathol 2014 Feb 26;27(2):175-83. Epub 2013 Jul 26.

1] Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA [2] Department of Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/modpathol.2013.138DOI Listing
February 2014

Effects of adjuvant chemoradiotherapy on the frequency and function of regulatory T cells in patients with head and neck cancer.

Clin Cancer Res 2013 Dec 4;19(23):6585-96. Epub 2013 Oct 4.

Authors' Affiliations: University of Pittsburgh Cancer Institute; University of Pittsburgh School of Medicine; Departments of Pathology, Immunology, and Otolaryngology, Pittsburgh, Pennsylvania; Department of Otolaryngology, University of Essen, Germany; and Department of Surgery, Fukushima Medical University, Fukushima, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855337PMC
December 2013

Conjunctival melanomas harbor BRAF and NRAS mutations--response.

Clin Cancer Res 2013 Nov 29;19(22):6331-2. Epub 2013 Oct 29.

Authors' Affiliations: Departments of Dermatology and Ophthalmology, University Hospital, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2368DOI Listing
November 2013

Vemurafenib reverses immunosuppression by myeloid derived suppressor cells.

Int J Cancer 2013 Oct 13;133(7):1653-63. Epub 2013 Apr 13.

Department of Dermatology, University Hospital, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/ijc.28168DOI Listing
October 2013

Reduced frequency of CD56 dim CD16 pos natural killer cells in pediatric systemic inflammatory response syndrome/sepsis patients.

Pediatr Res 2013 Oct 15;74(4):427-32. Epub 2013 Jul 15.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, Penn State Hershey Children's Hospital, Hershey, Pennsylvania.

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http://dx.doi.org/10.1038/pr.2013.121DOI Listing
October 2013

IRX-2, a novel immunotherapeutic, enhances functions of human dendritic cells.

PLoS One 2013 7;8(2):e47234. Epub 2013 Feb 7.

University of Pittsburgh, Department of Pathology and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047234PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567103PMC
September 2013

Immunological consequences of selective BRAF inhibitors in malignant melanoma: Neutralization of myeloid-derived suppressor cells.

Oncoimmunology 2013 Aug 10;2(8):e25218. Epub 2013 Jun 10.

Department of Dermatology; University Hospital; University Duisburg-Essen; Essen, Germany.

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http://dx.doi.org/10.4161/onci.25218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805652PMC
August 2013

Lack of SF3B1 R625 mutations in cutaneous melanoma.

Diagn Pathol 2013 May 21;8:87. Epub 2013 May 21.

Department of Dermatology, University Hospital, University Duisburg-Essen, Hufelandstrasse 55, Essen 45147, Germany.

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http://link.springer.com/content/pdf/10.1186%2F1746-1596-8-8
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http://diagnosticpathology.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/1746-1596-8-87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671181PMC
May 2013

Cutting edge: An inactive chromatin configuration at the IL-10 locus in human neutrophils.

J Immunol 2013 Mar 25;190(5):1921-5. Epub 2013 Jan 25.

Section of General Pathology, Department of Pathology and Diagnostics, University of Verona, 37134 Verona, Italy.

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http://dx.doi.org/10.4049/jimmunol.1203022DOI Listing
March 2013

Induced and natural regulatory T cells in human cancer.

Expert Opin Biol Ther 2012 Oct 31;12(10):1383-97. Epub 2012 Jul 31.

University of Pittsburgh Cancer Institute, Pathology, Hillman Cancer Center, 5117 Centre Ave, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1517/14712598.2012.707184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730844PMC
October 2012

Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples.

J Immunol Methods 2012 Jul 13;381(1-2):14-22. Epub 2012 Apr 13.

Departments of Pathology, Medical Oncology, Immunology and Otolaryngology, University of Pittsburgh Cancer Institute and University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.jim.2012.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385927PMC
July 2012

Phenotypic and functional characteristics of CD4+ CD39+ FOXP3+ and CD4+ CD39+ FOXP3neg T-cell subsets in cancer patients.

Eur J Immunol 2012 Jul 18;42(7):1876-85. Epub 2012 Jun 18.

Departments of Pathology, Immunology and Otolaryngology, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA

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http://doi.wiley.com/10.1002/eji.201142347
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http://dx.doi.org/10.1002/eji.201142347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689271PMC
July 2012

Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsets.

J Immunol Methods 2011 Jun 13;369(1-2):59-68. Epub 2011 Apr 13.

University of Pittsburgh Cancer Institute and University of Pittsburgh School of Medicine, Department of Pathology, 5117 Centre Ave, 15213 Pittsburgh, PA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002217591100079
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http://dx.doi.org/10.1016/j.jim.2011.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120012PMC
June 2011

Adjuvant pegylated interferon α-2b therapy for melanoma.

Oncol Lett 2010 Mar 1;1(2):237-241. Epub 2010 Mar 1.

Universitätsklinikum Essen, 45122 Essen, Germany.

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https://www.spandidos-publications.com/10.3892/ol_00000042
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http://dx.doi.org/10.3892/ol_00000042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436215PMC
March 2010