Bas van Steensel

Bas van Steensel

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Bas van Steensel

Publications by authors named "Bas van Steensel"

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Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER.

Methods Mol Biol 2019 ;1961:29-44

Division of Gene Regulation and Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-9170-9_3DOI Listing
July 2019

The role of transcription in shaping the spatial organization of the genome.

Nat Rev Mol Cell Biol 2019 Jun;20(6):327-337

European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.

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http://www.nature.com/articles/s41580-019-0114-6
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http://dx.doi.org/10.1038/s41580-019-0114-6DOI Listing
June 2019

Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs.

Cell 2019 May 11;177(4):852-864.e14. Epub 2019 Apr 11.

Division of Gene Regulation and Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506275PMC
May 2019

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler.

J Cell Biol 2018 11 28;217(11):4025-4048. Epub 2018 Aug 28.

Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL

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http://dx.doi.org/10.1083/jcb.201807108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219710PMC
November 2018

The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a.

Epigenetics Chromatin 2018 11 1;11(1):65. Epub 2018 Nov 1.

Department of Molecular Genetics of Cell, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia, 123182.

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https://epigeneticsandchromatin.biomedcentral.com/articles/1
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http://dx.doi.org/10.1186/s13072-018-0235-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211408PMC
November 2018

Scientific honesty and publicly shared lab notebooks: Sharing lab notebooks along with publication would increase transparency and help to improve honesty when reporting results.

Authors:
Bas van Steensel

EMBO Rep 2018 10 29;19(10). Epub 2018 Aug 29.

Oncode Institute and Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.15252/embr.201846866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172453PMC
October 2018

Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Epigenetics Chromatin 2018 07 3;11(1):38. Epub 2018 Jul 3.

Faculty of Biology, Ludwig-Maximilians-University Munich, Grosshaderner Strasse 2-4, 82152, Planegg, Martinsried, Germany.

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http://dx.doi.org/10.1186/s13072-018-0206-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029416PMC
July 2018

Easy quantification of template-directed CRISPR/Cas9 editing.

Nucleic Acids Res 2018 06;46(10):e58

Division of Gene Regulation, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.1093/nar/gky164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007333PMC
June 2018

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.

Mol Cell 2018 06 24;70(5):801-813.e6. Epub 2018 May 24.

Oncode Institute; Division of Gene Regulation, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993873PMC
June 2018

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Epigenetics Chromatin 2018 06 5;11(1):27. Epub 2018 Jun 5.

Faculty of Biology, Ludwig-Maximilians-University Munich, Grosshaderner Strasse 2-4, 82152, Planegg, Martinsried, Germany.

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http://dx.doi.org/10.1186/s13072-018-0196-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987561PMC
June 2018

High-throughput assessment of context-dependent effects of chromatin proteins.

Epigenetics Chromatin 2016 18;9:43. Epub 2016 Oct 18.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands ; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://epigeneticsandchromatin.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s13072-016-0096-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069885PMC
January 2018

CHRAC/ACF contribute to the repressive ground state of chromatin.

Life Sci Alliance 2018 Jan 9;1(1):e201800024. Epub 2018 Feb 9.

Molecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilian University Munich, Planegg-Martinsried, Germany.

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http://dx.doi.org/10.26508/lsa.201800024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238394PMC
January 2018

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence.

Genome Res 2017 10 15;27(10):1634-1644. Epub 2017 Sep 15.

Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1101/gr.225763.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630027PMC
October 2017

Comprehensive analysis of nucleocytoplasmic dynamics of mRNA in Drosophila cells.

PLoS Genet 2017 Aug 3;13(8):e1006929. Epub 2017 Aug 3.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1006929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557608PMC
August 2017

Clustering of housekeeping promoters facilitates their expression.

Genome Res 2017 07 18;27(7):1153-1161. Epub 2017 Apr 18.

Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1101/gr.211433.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495067PMC
July 2017

Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression.

Cell 2017 May;169(5):780-791

Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532494PMC
May 2017

Genome-nuclear lamina interactions: from cell populations to single cells.

Curr Opin Genet Dev 2017 Apr 17;43:67-72. Epub 2017 Jan 17.

Division of Gene Regulation, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2016.12.005DOI Listing
April 2017

Functional Enhancer Screening in Single Cells.

Mol Cell 2017 Apr;66(2):167-168

Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Department of Cell Biology, Erasmus University Medical Center, 3015GE Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.03.018DOI Listing
April 2017

Genome-wide mapping of autonomous promoter activity in human cells.

Nat Biotechnol 2017 02 26;35(2):145-153. Epub 2016 Dec 26.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1038/nbt.3754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498152PMC
February 2017

Inducible DamID systems for genomic mapping of chromatin proteins in Drosophila.

Nucleic Acids Res 2016 07 21;44(12):5646-57. Epub 2016 Mar 21.

Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands

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http://dx.doi.org/10.1093/nar/gkw176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937306PMC
July 2016

A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.

Genes Dev 2016 07;30(14):1645-57

Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1101/gad.283028.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973294PMC
July 2016

GENE REGULATION. A HUSH for transgene expression.

Science 2015 Jun;348(6242):1433-4

Department of Cell Biology, Erasmus University Medical Center, 3015 GE Rotterdam, Netherlands

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http://dx.doi.org/10.1126/science.aac6529DOI Listing
June 2015

Nuclear lamins are not required for lamina-associated domain organization in mouse embryonic stem cells.

EMBO Rep 2015 May 17;16(5):610-7. Epub 2015 Mar 17.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands

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http://dx.doi.org/10.15252/embr.201439789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428043PMC
May 2015

A short guide to technology development in cell biology.

Authors:
Bas van Steensel

J Cell Biol 2015 Mar;208(6):655-7

Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands Department of Cell Biology, Erasmus Medical Centre, 3015 CE Rotterdam, Netherlands

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http://dx.doi.org/10.1083/jcb.201502006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362452PMC
March 2015

Stochastic genome-nuclear lamina interactions: modulating roles of Lamin A and BAF.

Nucleus 2014 Mar-Apr;5(2):124-30. Epub 2014 Apr 9.

Division of Gene Regulation; Netherlands Cancer Institute; Amsterdam, the Netherlands.

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http://dx.doi.org/10.4161/nucl.28825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049918PMC
January 2015

Using TRIP for genome-wide position effect analysis in cultured cells.

Nat Protoc 2014 8;9(6):1255-81. Epub 2014 May 8.

1] Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands. [2] Cancer Genomics Centre, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2014.072DOI Listing
December 2014

Easy quantitative assessment of genome editing by sequence trace decomposition.

Nucleic Acids Res 2014 Dec 9;42(22):e168. Epub 2014 Oct 9.

Division of Gene Regulation, Netherlands Cancer Institute, Plesmanlaan 121, 1016 HM Amsterdam, the Netherlands

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http://dx.doi.org/10.1093/nar/gku936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267669PMC
December 2014

In search of the determinants of enhancer-promoter interaction specificity.

Trends Cell Biol 2014 Nov 24;24(11):695-702. Epub 2014 Aug 24.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA; Center for Computational Biology and Bioinformatics, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2014.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252644PMC
November 2014

Mechanisms and dynamics of nuclear lamina-genome interactions.

Curr Opin Cell Biol 2014 Jun 30;28:61-8. Epub 2014 Mar 30.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2014.03.003DOI Listing
June 2014

Differential programming of B cells in AID deficient mice.

PLoS One 2013 29;8(7):e69815. Epub 2013 Jul 29.

Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069815PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726761PMC
March 2014

Chromatin position effects assayed by thousands of reporters integrated in parallel.

Cell 2013 Aug;154(4):914-27

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.cell.2013.07.018DOI Listing
August 2013

The genomic landscape of the somatic linker histone subtypes H1.1 to H1.5 in human cells.

Cell Rep 2013 Jun 6;3(6):2142-54. Epub 2013 Jun 6.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U 964, Université de Strasbourg, 67404 Illkirch, France.

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http://dx.doi.org/10.1016/j.celrep.2013.05.003DOI Listing
June 2013

Chromatin organization: form to function.

Curr Opin Genet Dev 2013 Apr 26;23(2):185-90. Epub 2012 Dec 26.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S0959437X120014
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http://dx.doi.org/10.1016/j.gde.2012.11.011DOI Listing
April 2013

Genome architecture: domain organization of interphase chromosomes.

Cell 2013 Mar;152(6):1270-84

MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH42XU, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674130014
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http://dx.doi.org/10.1016/j.cell.2013.02.001DOI Listing
March 2013

Single-cell dynamics of genome-nuclear lamina interactions.

Cell 2013 Mar 21;153(1):178-92. Epub 2013 Mar 21.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.

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http://dx.doi.org/10.1016/j.cell.2013.02.028DOI Listing
March 2013

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence.

Genome Res 2013 Feb 2;23(2):270-80. Epub 2012 Nov 2.

Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1101/gr.141028.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561868PMC
February 2013

A network model of the molecular organization of chromatin in Drosophila.

Mol Cell 2013 Feb;49(4):759-71

Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S10972765130013
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http://dx.doi.org/10.1016/j.molcel.2013.01.040DOI Listing
February 2013

The inner nuclear membrane proteins Man1 and Ima1 link to two different types of chromatin at the nuclear periphery in S. pombe.

Nucleus 2012 Jan-Feb;3(1):77-87

Center for Biosciences, Department of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden.

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http://dx.doi.org/10.4161/nucl.18825DOI Listing
December 2012

Mapping of lamin A- and progerin-interacting genome regions.

Chromosoma 2012 Oct 19;121(5):447-64. Epub 2012 May 19.

Genome Cell Biology Group, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00412-012-0376-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443488PMC
October 2012

Hox in space: gene cluster regulation linked to folding of chromatin.

Nucleus 2012 Mar 1;3(2):118-22. Epub 2012 Mar 1.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4161/nucl.19159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383564PMC
March 2012

Chromatin: constructing the big picture.

Authors:
Bas van Steensel

EMBO J 2011 May 28;30(10):1885-95. Epub 2011 Apr 28.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/emboj.2011.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098493PMC
May 2011

Interactions among Polycomb domains are guided by chromosome architecture.

PLoS Genet 2011 Mar 24;7(3):e1001343. Epub 2011 Mar 24.

Division of Molecular Genetics and Centre for Biomedical Genetics, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1001343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063757PMC
March 2011

A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands.

Curr Biol 2010 Oct 7;20(20):1787-98. Epub 2010 Oct 7.

Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK.

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http://dx.doi.org/10.1016/j.cub.2010.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763543PMC
October 2010

Genomics tools for unraveling chromosome architecture.

Nat Biotechnol 2010 Oct;28(10):1089-95

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nbt.1680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023824PMC
October 2010

Genome-nuclear lamina interactions and gene regulation.

Curr Opin Cell Biol 2010 Jun 3;22(3):320-5. Epub 2010 May 3.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ceb.2010.04.002DOI Listing
June 2010

Bayesian network analysis of targeting interactions in chromatin.

Genome Res 2010 Feb 9;20(2):190-200. Epub 2009 Dec 9.

Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.1101/gr.098822.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813475PMC
February 2010

Reassessing the abundance of H3K9me2 chromatin domains in embryonic stem cells.

Nat Genet 2010 Jan;42(1):4; author reply 5-6

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http://dx.doi.org/10.1038/ng0110-4DOI Listing
January 2010

Histone H1 binding is inhibited by histone variant H3.3.

EMBO J 2009 Dec 15;28(23):3635-45. Epub 2009 Oct 15.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/emboj.2009.301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790488PMC
December 2009

Chromatin domains in higher eukaryotes: insights from genome-wide mapping studies.

Chromosoma 2009 Feb 14;118(1):25-36. Epub 2008 Oct 14.

Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00412-008-0186-0DOI Listing
February 2009

High-resolution mapping of heterochromatin redistribution in a Drosophila position-effect variegation model.

Epigenetics Chromatin 2009 Jan 29;2(1). Epub 2009 Jan 29.

Division of Gene Regulation, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1756-8935-2-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644302PMC
January 2009

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions.

Nature 2008 Jun 7;453(7197):948-51. Epub 2008 May 7.

Division of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nature06947DOI Listing
June 2008

Linking cohesin to gene regulation.

Cell 2008 Mar;132(6):925-8

Division of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.cell.2008.03.001DOI Listing
March 2008

Global chromatin domain organization of the Drosophila genome.

PLoS Genet 2008 Mar 28;4(3):e1000045. Epub 2008 Mar 28.

Department of Molecular Biology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1000045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2274884PMC
March 2008

Detection of in vivo protein-DNA interactions using DamID in mammalian cells.

Nat Protoc 2007 ;2(6):1467-78

Division of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2007.148DOI Listing
August 2007

SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila.

J Cell Sci 2007 Jul;120(Pt 14):2344-51

Institute of Cytology and Genetics of Siberian Division, Russian Academy of Sciences, Novosibirsk 630090, Russia.

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http://dx.doi.org/10.1242/jcs.006007DOI Listing
July 2007

High-resolution mapping reveals links of HP1 with active and inactive chromatin components.

PLoS Genet 2007 Mar;3(3):e38

Department of Molecular Biology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.0030038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808074PMC
March 2007

HP1 controls genomic targeting of four novel heterochromatin proteins in Drosophila.

EMBO J 2007 Feb 25;26(3):741-51. Epub 2007 Jan 25.

Department of Molecular Biology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/sj.emboj.7601527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794385PMC
February 2007

DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase.

Methods Enzymol 2006 ;410:342-59

Division of Molecular Biology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/S0076-6879(06)10016-6DOI Listing
December 2006

Human heterochromatin proteins form large domains containing KRAB-ZNF genes.

Genome Res 2006 Dec 12;16(12):1493-504. Epub 2006 Oct 12.

Division of Molecular Biology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1101/gr.5391806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665633PMC
December 2006

Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells.

Dev Cell 2006 Dec;11(6):775-89

The Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S153458070600408
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http://dx.doi.org/10.1016/j.devcel.2006.09.015DOI Listing
December 2006

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C).

Nat Genet 2006 Nov 8;38(11):1348-54. Epub 2006 Oct 8.

Department of Cell Biology and Genetics, Erasmus Medical Centre, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng1896DOI Listing
November 2006

Characterization of the Drosophila melanogaster genome at the nuclear lamina.

Nat Genet 2006 Sep 30;38(9):1005-14. Epub 2006 Jul 30.

Department of Tumor Biology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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http://www.nature.com/articles/ng1852
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http://dx.doi.org/10.1038/ng1852DOI Listing
September 2006

Histone modifications: from genome-wide maps to functional insights.

Genome Biol 2005 31;6(6):113. Epub 2005 May 31.

Netherlands Cancer Institute, Plesmanlaan 121,1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/gb-2005-6-6-113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175962PMC
August 2006

Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster.

Proc Natl Acad Sci U S A 2006 Aug 31;103(32):12027-32. Epub 2006 Jul 31.

Department of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0605003103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567692PMC
August 2006

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.

Nat Genet 2006 Jun 20;38(6):694-9. Epub 2006 Apr 20.

Division of Molecular Genetics, and the Centre for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng1792DOI Listing
June 2006

Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex.

Genes Dev 2006 Apr 17;20(7):858-70. Epub 2006 Mar 17.

Adolf-Butenandt-Institut, Molekularbiologie, Ludwig-Maximilians-Universität München, 80336 München, Germany.

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http://dx.doi.org/10.1101/gad.1399406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475731PMC
April 2006

Genome-wide HP1 binding in Drosophila: developmental plasticity and genomic targeting signals.

Genome Res 2005 Sep 18;15(9):1265-73. Epub 2005 Aug 18.

Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1101/gr.3198905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199541PMC
September 2005

Whole-genome views of chromatin structure.

Chromosome Res 2005 ;13(3):289-98

Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands.

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http://dx.doi.org/10.1007/s10577-005-2166-zDOI Listing
August 2005

Mapping of genetic and epigenetic regulatory networks using microarrays.

Authors:
Bas van Steensel

Nat Genet 2005 Jun;37 Suppl:S18-24

the Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.1038/ng1559DOI Listing
June 2005

Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila.

Proc Natl Acad Sci U S A 2003 Aug 22;100(16):9428-33. Epub 2003 Jul 22.

Department of Genetics and Biostatistics Division, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1073/pnas.1533393100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC170935PMC
August 2003

Epigenomic profiling using microarrays.

Biotechniques 2003 Aug;35(2):346-50, 352-4, 356-7

Netherlands Cancer Institute, Amsterdam, The Netherlands.

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https://www.future-science.com/doi/10.2144/03352rv01
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August 2003

Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network.

Genes Dev 2003 May 14;17(9):1101-14. Epub 2003 Apr 14.

Division of Basic Sciences and Divison of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1101/gad.1066903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC196053PMC
May 2003

Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding.

Proc Natl Acad Sci U S A 2003 Mar 24;100(5):2580-5. Epub 2003 Feb 24.

Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0438000100
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http://dx.doi.org/10.1073/pnas.0438000100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151383PMC
March 2003

Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing.

Nat Genet 2002 Nov 30;32(3):438-42. Epub 2002 Sep 30.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1038/ng1005DOI Listing
November 2002

Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3.

Curr Biol 2002 Jan;12(1):65-8

Howard Hughes Medical Institute and Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/s0960-9822(01)00622-4DOI Listing
January 2002