Barton F Haynes

Barton F Haynes

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Barton F Haynes

Barton F Haynes

Publications by authors named "Barton F Haynes"

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Engineering immunity for next generation HIV vaccines: The intersection of bioengineering and immunology.

Vaccine 2020 Jan 20;38(2):187-193. Epub 2019 Nov 20.

Division of Discovery Science and Technology, NIBIB, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.vaccine.2019.10.036DOI Listing
January 2020

Multiple roles for HIV broadly neutralizing antibodies.

Sci Transl Med 2019 Oct;11(516)

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20014, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaz2686DOI Listing
October 2019

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template.

Cell Rep 2019 05;27(8):2426-2441.e6

Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; International AIDS Vaccine Initiative, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.04.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533203PMC
May 2019

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.

Immunity 2019 03 12;50(3):677-691.e13. Epub 2019 Mar 12.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193007
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http://dx.doi.org/10.1016/j.immuni.2019.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555550PMC
March 2019

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.

Cell Rep 2018 12;25(11):3123-3135.e6

National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu Natal, Durban 4041, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.11.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342559PMC
December 2018

RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.

Cell 2018 10 27;175(2):387-399.e17. Epub 2018 Sep 27.

Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA; Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.08.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176872PMC
October 2018

Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency.

Cell Rep 2018 10;25(1):107-117.e3

UNC HIV Cure Center and Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258175PMC
October 2018

Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.

Cell Host Microbe 2018 06 31;23(6):759-765.e6. Epub 2018 May 31.

Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 22710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002614PMC
June 2018

Correlation Between Anti-gp41 Antibodies and Virus Infectivity Decay During Primary HIV-1 Infection.

Front Microbiol 2018 20;9:1326. Epub 2018 Jun 20.

Theoretical Biology and Biophysics Group, MS K710, Los Alamos National Laboratory, Los Alamos, NM, United States.

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http://dx.doi.org/10.3389/fmicb.2018.01326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019451PMC
June 2018

Cross-reactivity of HIV vaccine responses and the microbiome.

Curr Opin HIV AIDS 2018 Jan;13(1):9-14

Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.

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http://dx.doi.org/10.1097/COH.0000000000000423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890927PMC
January 2018

Development of a recombinant yellow fever vector expressing a HIV clade C founder envelope gp120.

J Virol Methods 2017 11 31;249:85-93. Epub 2017 Aug 31.

Human Vaccine Institute and Department of Medicine, Duke University Medical Center, Durham, NC 27710, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jviromet.2017.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623118PMC
November 2017

Developing an HIV vaccine.

Science 2017 03 16;355(6330):1129-1130. Epub 2017 Mar 16.

Department of Immunology and Microbiology, Scripps Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery, International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1126/science.aan0662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569908PMC
March 2017

BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance.

Cell Rep 2017 02;18(7):1627-1635

Department of Immunology, Duke University, Durham, NC 27710, USA; Human Vaccine Institute, Duke University, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.01.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328188PMC
February 2017

Broadly Neutralizing Antibodies Display Potential for Prevention of HIV-1 Infection of Mucosal Tissue Superior to That of Nonneutralizing Antibodies.

J Virol 2017 Jan 16;91(1). Epub 2016 Dec 16.

Imperial College London, Department of Medicine, Section of Virology, Group of Mucosal Infection and Immunity, London, United Kingdom

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http://dx.doi.org/10.1128/JVI.01762-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165208PMC
January 2017

The quest for an antibody-based HIV vaccine.

Immunol Rev 2017 01;275(1):5-10

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/imr.12517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384259PMC
January 2017

Host controls of HIV broadly neutralizing antibody development.

Immunol Rev 2017 01;275(1):79-88

Departments of Immunology and Medicine, Duke University School of Medicine, Duke Human Vaccine Institute, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1111/imr.12508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479487PMC
January 2017

Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection.

Nat Rev Drug Discov 2016 12 7;15(12):823-834. Epub 2016 Oct 7.

Department of Surgery, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/nrd.2016.173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549020PMC
December 2016

Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection.

EBioMedicine 2016 12 21;14:97-111. Epub 2016 Nov 21.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA; Department of Laboratory Medicine, University of Washington, Seattle, WA, USA; Department of Global Health, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161443PMC
December 2016