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Bart Staels

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100Publications

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Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response.

Authors:

Marie Bobowski-Gerard Francesco Paolo Zummo Bart Staels Philippe Lefebvre Jérôme Eeckhoute

Cells 2018 Sep 13;7(9). Epub 2018 Sep 13.

Institut Pasteur de Lille, The University of Lille, Inserm, CHU Lille, U1011-EGID, F-59000 Lille, France.

September 2018

MuscleJ: a high-content analysis method to study skeletal muscle with a new Fiji tool.

Authors:

Alicia Mayeuf-Louchart David Hardy Quentin Thorel Pascal Roux Lorna Gueniot David Briand Aurélien Mazeraud Adrien Bouglé Spencer L Shorte Bart Staels Fabrice Chrétien Hélène Duez Anne Danckaert

Skelet Muscle 2018 08 6;8(1):25. Epub 2018 Aug 6.

Experimental Neuropathology Unit, Infection and Epidemiology Department, Institut Pasteur, 25, rue du Docteur Roux, 75015, Paris, France.

August 2018

Keratinocyte expression of A20/TNFAIP3 controls skin inflammation associated with atopic dermatitis and psoriasis.

Authors:

Michael Devos Denis A Mogilenko Sébastien Fleury Barbara Gilbert Coralie Becquart Sandrine Quemener Hélène Dehondt Peter Tougaard Bart Staels Claus Bachert Peter Vandenabeele Geert Van Loo Delphine Staumont-Salle Wim Declercq David Dombrowicz

J Invest Dermatol 2018 Aug 14. Epub 2018 Aug 14.

Université de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France. Electronic address:

August 2018

Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes.

Diabetes 2018 07 4;67(7):1310-1321. Epub 2018 May 4.

University Lille, Centre National de la Recherche Scientifique, Institut Pasteur de Lille, UMR 8199 - European Genomic Institute for Diabetes, Lille, France

July 2018

The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis.

Authors:

Maheul Ploton Claire Mazuy Céline Gheeraert Vanessa Dubois Alexandre Berthier Julie Dubois-Chevalier Xavier Maréchal Kadiombo Bantubungi Hélène Diemer Sarah Cianférani Jean-Marc Strub Audrey Helleboid-Chapman Jérôme Eeckhoute Bart Staels Philippe Lefebvre

J Hepatol 2018 Jul 5. Epub 2018 Jul 5.

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France. Electronic address:

July 2018

Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle.

Authors:

Jakob Wefers Dirk van Moorsel Jan Hansen Niels J Connell Bas Havekes Joris Hoeks Wouter D van Marken Lichtenbelt Hélène Duez Esther Phielix Andries Kalsbeek Mark V Boekschoten Guido J Hooiveld Matthijs K C Hesselink Sander Kersten Bart Staels Frank A J L Scheer Patrick Schrauwen

Proc Natl Acad Sci U S A 2018 07 9;115(30):7789-7794. Epub 2018 Jul 9.

Department of Nutrition and Movement Sciences, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands;

July 2018

Molecular actions of PPARα in lipid metabolism and inflammation.

Authors:

Nadia Bougarne Basiel Weyers Sofie J Desmet Julie Deckers David W Ray Bart Staels Karolien De Bosscher

Endocr Rev 2018 Jul 17. Epub 2018 Jul 17.

Department of Biomolecular Medicine, Ghent University, 9000 Ghent, Belgium, Receptor Research Laboratories, Nuclear Receptor Lab, VIB Center for Medical Biotechnology, 9000 Ghent, Belgium.

July 2018

Peri-operative acute kidney injury upon cardiac surgery time-of-day.

Authors:

Sandro Ninni Claire Seunes Staniel Ortmans Stéphanie Mouton Thomas Modine Mohamed Koussa Bruno Jegou Jean-Louis Edme Bart Staels David Montaigne Augustin Coisne

Int J Cardiol 2018 Jul 19. Epub 2018 Jul 19.

CHU Lille, Department of Clinical Physiology and Echocardiography, Heart Valve Clinic, F-59000 Lille, France; European Genomic Institute for Diabetes (E.G.I.D), Univ Lille, F-59000 Lille, France; Inserm, U1011, F-59000 Lille, France; Institut Pasteur de Lille, F-59019 Lille, France. Electronic address:

July 2018

Endospanin-2 enhances skeletal muscle energy metabolism and running endurance capacity.

JCI Insight 2018 May 3;3(9). Epub 2018 May 3.

Université de Lille, U1011 - EGID, F-59000 Lille, France.

May 2018

Arterial Pulsatility and Circulating von Willebrand Factor in Patients on Mechanical Circulatory Support.

J Am Coll Cardiol 2018 May;71(19):2106-2118

University of Lille, INSERM U1011-EGID, Lille, France; Institut Pasteur de Lille, Lille, France; CHU Lille, Hematology Transfusion, Lille, France. Electronic address:

May 2018

Daytime variations in perioperative myocardial injury - Authors' reply.

Authors:

David Montaigne Augustin Coisne Xavier Marechal Philippe Lefebvre Bart Staels

Lancet 2018 May 24;391(10135):2106. Epub 2018 May 24.

University of Lille, EGID, F-59000 Lille, France; Inserm, U1011, F-Lille, France; University Hospital CHU Lille, Lille, France; Institut Pasteur de Lille, Lille, France.

May 2018

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.

Gastroenterology 2018 04 24;154(5):1449-1464.e20. Epub 2017 Dec 24.

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France. Electronic address:

April 2018

Alternative macrophages in atherosclerosis: not always protective!

Authors:

Benoit Pourcet Bart Staels

J Clin Invest 2018 Mar 19;128(3):910-912. Epub 2018 Feb 19.

March 2018

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Authors:

Emilie Catry Laure B Bindels Anne Tailleux Sophie Lestavel Audrey M Neyrinck Jean-François Goossens Irina Lobysheva Hubert Plovier Ahmed Essaghir Jean-Baptiste Demoulin Caroline Bouzin Barbara D Pachikian Patrice D Cani Bart Staels Chantal Dessy Nathalie M Delzenne

Gut 2018 02 4;67(2):271-283. Epub 2017 Apr 4.

Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.

February 2018

Risperidone-induced metabolic dysfunction is attenuated by Curcuma longa extract administration in mice.

Authors:

Florent Auger Françoise Martin Olivier Pétrault Jennifer Samaillie Thierry Hennebelle Mohamed-Sami Trabelsi François Bailleul Bart Staels Régis Bordet Patrick Duriez

Metab Brain Dis 2018 Feb 16;33(1):63-77. Epub 2017 Oct 16.

Inserm, CHU Lille, U1171 - Degenerative & Vascular Cognitive Disorders, University of Lille, F-59000, Lille, France.

February 2018

Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study.

Lancet 2018 01 26;391(10115):59-69. Epub 2017 Oct 26.

University of Lille, EGID, Lille, France; Inserm, U1011, Lille, France; University Hospital CHU Lille, Lille, France; Institut Pasteur de Lille, Lille, France.

January 2018

Circadian control of metabolism and pathological consequences of clock perturbations.

Authors:

Alicia Mayeuf-Louchart Mathilde Zecchin Bart Staels Hélène Duez

Biochimie 2017 Dec 2;143:42-50. Epub 2017 Aug 2.

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France. Electronic address:

December 2017

The tumour suppressor CDKN2A/p16 regulates adipogenesis and bone marrow-dependent development of perivascular adipose tissue.

Authors:

Kristiaan Wouters Yann Deleye Sarah A Hannou Jonathan Vanhoutte Xavier Maréchal Augustin Coisne Madjid Tagzirt Bruno Derudas Emmanuel Bouchaert Christian Duhem Emmanuelle Vallez Casper G Schalkwijk François Pattou David Montaigne Bart Staels Réjane Paumelle

Diab Vasc Dis Res 2017 11 2;14(6):516-524. Epub 2017 Sep 2.

1 Université Lille 2, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France.

November 2017

Organizing combinatorial transcription factor recruitment at cis-regulatory modules.

Authors:

Julie Dubois-Chevalier Parisa Mazrooei Mathieu Lupien Bart Staels Philippe Lefebvre Jérôme Eeckhoute

Transcription 2018 28;9(4):233-239. Epub 2017 Nov 28.

a Université de Lille - Inserm - Chru de Lille, Institut Pasteur de Lille , U1011- EGID, F-59000 Lille , France.

November 2017

Ffar2 expression regulates leukaemic cell growth in vivo.

Authors:

Laure B Bindels Paolo E Porporato Sarah Ducastel Martina Sboarina Audrey M Neyrinck Evelyne M Dewulf Olivier Feron Sophie Lestavel Patrice D Cani Bart Staels Pierre Sonveaux Nathalie M Delzenne

Br J Cancer 2017 Oct 5;117(9):1336-1340. Epub 2017 Sep 5.

Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain, Avenue Mounier 73, Box B1.73.11, Brussels 1200, Belgium.

October 2017

Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects.

Authors:

Vanessa Legry Sven Francque Joel T Haas An Verrijken Sandrine Caron Oscar Chávez-Talavera Emmanuelle Vallez Luisa Vonghia Eveline Dirinck Ann Verhaegen Mostafa Kouach Sophie Lestavel Philippe Lefebvre Luc Van Gaal Anne Tailleux Réjane Paumelle Bart Staels

J Clin Endocrinol Metab 2017 10;102(10):3783-3794

Université Lille, INSERM, Centre Hospitalier Universitaire de Lille, Institut Pasteur de Lille, U1011-European Genomic Institute for Diabetes, F-59000 Lille, France.

October 2017

Fasting the Microbiota to Improve Metabolism?

Authors:

Joel T Haas Bart Staels

Cell Metab 2017 Oct;26(4):584-585

European Genomic Institute for Diabetes (E.G.I.D), University of Lille, EGID, 59000 Lille, France; INSERM UMR 1011, 59000 Lille, France; Institut Pasteur de Lille, 59000 Lille, France; University Hospital CHU Lille, 59000 Lille, France. Electronic address:

October 2017

The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ.

Sci Rep 2017 Oct 26;7(1):14087. Epub 2017 Oct 26.

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France.

October 2017

Rev-erb-α regulates atrophy-related genes to control skeletal muscle mass.

Authors:

Alicia Mayeuf-Louchart Quentin Thorel Stéphane Delhaye Justine Beauchamp Christian Duhem Anne Danckaert Steve Lancel Benoit Pourcet Estelle Woldt Alexis Boulinguiez Lise Ferri Mathilde Zecchin Bart Staels Yasmine Sebti Hélène Duez

Sci Rep 2017 Oct 30;7(1):14383. Epub 2017 Oct 30.

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France.

October 2017

Mitochondria and endoplasmic reticulum: Targets for a better insulin sensitivity in skeletal muscle?

Authors:

Alexis Boulinguiez Bart Staels Hélène Duez Steve Lancel

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Sep 18;1862(9):901-916. Epub 2017 May 18.

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France. Electronic address:

September 2017

Anti-diabetic activity of fused PPARγ-SIRT1 ligands with limited body-weight gain by mimicking calorie restriction and decreasing SGK1 expression.

Authors:

Celine Pirat Catherine Dacquet Veronique Leclerc Nathalie Hennuyer Monique Beucher-Gaudin Ghislaine Zanirato Anne Géant Bart Staels Alain Ktorza Amaury Farce Daniel-Henri Caignard Pascal Berthelot Nicolas Lebegue

Eur J Med Chem 2017 Sep 12;137:310-326. Epub 2017 Jun 12.

Univ. Lille, Inserm, CHU Lille, UMR-S 1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, F-59000 Lille, France. Electronic address:

September 2017

Intestinal bile acid receptors are key regulators of glucose homeostasis.

Authors:

Mohamed-Sami Trabelsi Sophie Lestavel Bart Staels Xavier Collet

Proc Nutr Soc 2017 08 16;76(3):192-202. Epub 2016 Nov 16.

Institut National de la Santé et de la Recherche Médicale, U1048, Université Paul Sabatier, UPS, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC),CHU Rangueil,1 Avenue Jean Poulhès,BP84225, 31432 Toulouse,Cedex 4,France.

August 2017

Tau deletion promotes brain insulin resistance.

J Exp Med 2017 Aug 26;214(8):2257-2269. Epub 2017 Jun 26.

Université de Lille, Institut National de la Santé et de la Recherche Medicale (INSERM), CHU Lille, UMR-S 1172 JPArc, Lille, France

August 2017

Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms.

Authors:

Bart Staels

Am J Cardiol 2017 Jul 30;120(1S):S28-S36. Epub 2017 May 30.

Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France. Electronic address:

July 2017

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin.

JCI Insight 2017 Jul 6;2(13). Epub 2017 Jul 6.

University Lille, Inserm, CHU-Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France.

July 2017

Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways.

Authors:

Mickael Rosa Camille Paris Yoann Sottejeau Delphine Corseaux Emmanuel Robin Madjid Tagzirt Francis Juthier Ramadan Jashari Antoine Rauch André Vincentelli Bart Staels Eric Van Belle Sophie Susen Annabelle Dupont

Acta Diabetol 2017 Jun 18;54(6):551-560. Epub 2017 Mar 18.

European Genomic Institute for Diabetes (E.G.I.D.), FR 3508, UNIV LILLE, Inserm UMR 1011, 59000, Lille, France.

June 2017

The logic of transcriptional regulator recruitment architecture at -regulatory modules controlling liver functions.

Authors:

Julie Dubois-Chevalier Vanessa Dubois Hélène Dehondt Parisa Mazrooei Claire Mazuy Aurélien A Sérandour Céline Gheeraert Penderia Guillaume Eric Baugé Bruno Derudas Nathalie Hennuyer Réjane Paumelle Guillemette Marot Jason S Carroll Mathieu Lupien Bart Staels Philippe Lefebvre Jérôme Eeckhoute

Genome Res 2017 06 11;27(6):985-996. Epub 2017 Apr 11.

Université Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000 Lille, France.

June 2017

Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity.

Authors:

Giulia Chinetti-Gbaguidi Mehdi Daoudi Mickael Rosa Manjula Vinod Loïc Louvet Corinne Copin Mélanie Fanchon Jonathan Vanhoutte Bruno Derudas Loic Belloy Stephan Haulon Christophe Zawadzki Sophie Susen Ziad A Massy Jérôme Eeckhoute Bart Staels

Circ Res 2017 Jun 24;121(1):19-30. Epub 2017 Apr 24.

From the Université de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Lille, France (G.C.-G., M.D., M.R., M.V., C.C., M.F., J.V., B.D., L.B., C.Z., S.S., J.E., B.S.); University of Côte d'Azur, CHU, Inserm, CNRS, IRCAN, Nice, France (G.C.-G.); Inserm U1088, University of Picardie Jules Verne, and Amiens University Hospital, Amiens, France (L.L.); CHU Lille, Lille, France (S.H.); Division of Nephrology, Ambroise Paré University Hospital, AP-HP, Boulogne-Billancourt (Z.A.M.); and INSERM U1018, Team 5, CESP, UVSQ, Paris-Saclay University, Villejuif/Paris, France (Z.A.M.).

June 2017

Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms.

Authors:

Bart Staels

Am J Med 2017 Jun;130(6S):S30-S39

Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France. Electronic address:

June 2017

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease.

Authors:

Oscar Chávez-Talavera Anne Tailleux Philippe Lefebvre Bart Staels

Gastroenterology 2017 05 15;152(7):1679-1694.e3. Epub 2017 Feb 15.

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France. Electronic address:

May 2017

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance.

Authors:

Manuel Lasalle Vanessa Hoguet Nathalie Hennuyer Florence Leroux Catherine Piveteau Loïc Belloy Sophie Lestavel Emmanuelle Vallez Emilie Dorchies Isabelle Duplan Emmanuel Sevin Maxime Culot Fabien Gosselet Rajaa Boulahjar Adrien Herledan Bart Staels Benoit Deprez Anne Tailleux Julie Charton

J Med Chem 2017 May 5;60(10):4185-4211. Epub 2017 May 5.

Univ. Lille, Inserm, Institut Pasteur de Lille, U1177 - Drugs and Molecules for Living Systems, F-59000 Lille, France.

May 2017

The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model.

Authors:

Michael Joubert Benoît Jagu David Montaigne Xavier Marechal Angela Tesse Audrey Ayer Lucile Dollet Cédric Le May Gilles Toumaniantz Alain Manrique Flavien Charpentier Bart Staels Jocelyne Magré Bertrand Cariou Xavier Prieur

Diabetes 2017 04 4;66(4):1030-1040. Epub 2017 Jan 4.

L'Institut du Thorax, INSERM, CNRS, Université de Nantes, Nantes, France

April 2017

Distinct but complementary contributions of PPAR isotypes to energy homeostasis.

Authors:

Vanessa Dubois Jérôme Eeckhoute Philippe Lefebvre Bart Staels

J Clin Invest 2017 Apr 3;127(4):1202-1214. Epub 2017 Apr 3.

April 2017

Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals.

Authors:

Rémy Le Guével Frédérik Oger Celia P Martinez-Jimenez Maud Bizot Céline Gheeraert François Firmin Maheul Ploton Miroslava Kretova Gaëlle Palierne Bart Staels Peter Barath Iannis Talianidis Philippe Lefebvre Jérôme Eeckhoute Gilles Salbert

ACS Chem Biol 2017 03 13;12(3):654-663. Epub 2017 Jan 13.

Université Rennes 1 , F-35042 Rennes, France.

March 2017

Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia.

Authors:

Camille Dugardin Olivier Briand Véronique Touche Marleen Schonewille François Moreau Cédric Le May Albert K Groen Bart Staels Sophie Lestavel

Acta Diabetol 2017 Feb 28;54(2):191-199. Epub 2016 Oct 28.

Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, Univ. Lille, 59000, Lille, France.

February 2017

DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: Putative mechanisms through PPAR activation.

Authors:

Rémy Bosviel Laurie Joumard-Cubizolles Giulia Chinetti-Gbaguidi Dominique Bayle Corinne Copin Nathalie Hennuyer Isabelle Duplan Bart Staels Giuseppe Zanoni Alessio Porta Laurence Balas Jean-Marie Galano Camille Oger Andrzej Mazur Thierry Durand Cécile Gladine

Free Radic Biol Med 2017 02 14;103:146-154. Epub 2016 Dec 14.

INRA, UMR 1019, UNH, CRNH Auvergne, F-63000 Clermont-Ferrand, France; Clermont Université, Université d'Auvergne, Unité de Nutrition Humaine, BP 10448, F-63000 Clermont-Ferrand, France. Electronic address:

February 2017

Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase.

Authors:

Branko Simic Pavani Mocharla Margot Crucet Elena Osto Adelheid Kratzer Simona Stivala Susan Kühnast Thimoteus Speer Petia Doycheva Hans M Princen Jose W van der Hoorn J Wouter Jukema Hector Giral Anne Tailleux Ulf Landmesser Bart Staels Thomas F Lüscher

Atherosclerosis 2017 02 16;257:186-194. Epub 2017 Jan 16.

Center for Molecular Cardiology, Campus Schlieren, University of Zürich, Switzerland; University Heart Center, Cardiology, University Hospital Zürich, Switzerland. Electronic address:

February 2017

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD.

Authors:

Barbara Gross Michal Pawlak Philippe Lefebvre Bart Staels

Nat Rev Endocrinol 2017 01 16;13(1):36-49. Epub 2016 Sep 16.

Université de Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000 Lille, France.

January 2017

Pathophysiology and Mechanisms of Nonalcoholic Fatty Liver Disease.

Authors:

Joel T Haas Sven Francque Bart Staels

Annu Rev Physiol 2016 30;78:181-205. Epub 2015 Nov 30.

European Genomic Institute for Diabetes (EGID), FR 3508, F-59000 Lille, France; email: ,

December 2016

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.

Authors:

Dariusz Ratman Viacheslav Mylka Nadia Bougarne Michal Pawlak Sandrine Caron Nathalie Hennuyer Réjane Paumelle Lode De Cauwer Jonathan Thommis Mark H Rider Claude Libert Sam Lievens Jan Tavernier Bart Staels Karolien De Bosscher

Nucleic Acids Res 2016 12 30;44(22):10539-10553. Epub 2016 Aug 30.

Receptor Research Laboratories, Nuclear Receptor Lab, Medical Biotechnology Center, VIB, 9000 Ghent, Belgium

December 2016

An oxidative stress paradox: time for a conceptual change?

Authors:

Joel T Haas Bart Staels

Diabetologia 2016 12 1;59(12):2514-2517. Epub 2016 Oct 1.

Université de Lille, European Genomic Institute for Diabetes (EGID), U1011, Lille, France.

December 2016

ORP4L Facilitates Macrophage Survival via G-Protein-Coupled Signaling: ORP4L-/- Mice Display a Reduction of Atherosclerosis.

Authors:

Wenbin Zhong Guoping Pan Lin Wang Shiqian Li Jingsong Ou Mengyang Xu Jiwei Li Biying Zhu Xiuye Cao Hongling Ma Chaowen Li Jun Xu Vesa M Olkkonen Bart Staels Daoguang Yan

Circ Res 2016 Dec 11;119(12):1296-1312. Epub 2016 Oct 11.

From the Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Department of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, China (W.Z., G.P., L.W., J.L., B.Z., X.C., H.M., C.L., D.Y.); Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland (S.L., V.M.O.); Division of Cardiac Surgery, the First Affiliated Hospital (J.O.) and Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (M.X., J.X.); and U1011 Inserm, EGID, Université Lille, CHU Lille, Institut Pasteur de Lille, France (B.S.).

December 2016

Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets.

Authors:

Leonardo A Moraes Amanda J Unsworth Sakthivel Vaiyapuri Marfoua S Ali Parvathy Sasikumar Tanya Sage Gagan D Flora Alex P Bye Neline Kriek Emilie Dorchies Olivier Molendi-Coste David Dombrowicz Bart Staels David Bishop-Bailey Jonathan M Gibbins

Arterioscler Thromb Vasc Biol 2016 12 6;36(12):2324-2333. Epub 2016 Oct 6.

Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, Harborne Building, University of Reading, Reading, Berkshire, RG6 6AS, UK.

December 2016

Omentin-1, epicardial fat and coronary artery disease.

Authors:

Cedric Klein Sandro Ninni Augustin Coisne Bart Staels David Montaigne

Atherosclerosis 2016 12 13;255:224-225. Epub 2016 Oct 13.

CHU de Lille, Department of Echocardiography and Cardiovascular explorations, Lille, France; European Genomic Institute for Diabetes (E.G.I.D), FR 3508, F-59000, Lille, France; Univ Lille, F-59000, Lille, France; Inserm UMR 1011, F-59000, Lille, France; Institut Pasteur de Lille, F-59000, Lille, France.

December 2016

Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function.

Authors:

Julien Bricambert Dimitri Favre Saška Brajkovic Amélie Bonnefond Raphael Boutry Roberto Salvi Valérie Plaisance Mohamed Chikri Giulia Chinetti-Gbaguidi Bart Staels Vittorio Giusti Robert Caiazzo François Pattou Gérard Waeber Philippe Froguel Amar Abderrahmani

Mol Metab 2016 12 5;5(12):1200-1207. Epub 2016 Oct 5.

Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8199 - EGID, F-59000 Lille, France; Department of Genomic of Common Disease, Imperial College London, UK. Electronic address:

December 2016

Natalizumab Treatment Modulates Peroxisome Proliferator-Activated Receptors Expression in Women with Multiple Sclerosis.

Authors:

Véronique Ferret-Sena Alexandra Maia E Silva Armando Sena Inês Cavaleiro José Vale Bruno Derudas Giulia Chinetti-Gbaguidi Bart Staels

PPAR Res 2016 18;2016:5716415. Epub 2016 Dec 18.

University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.

December 2016

Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression.

Gut 2016 11 3;65(11):1882-1894. Epub 2015 Sep 3.

INSERM, U970, Paris Cardiovascular Research Center-PARCC, Paris, France.

November 2016

Innate lymphoid cells contribute to allergic airway disease exacerbation by obesity.

Authors:

Laetitia Everaere Saliha Ait-Yahia Olivier Molendi-Coste Han Vorng Sandrine Quemener Pauline LeVu Sebastien Fleury Emmanuel Bouchaert Ying Fan Catherine Duez Patricia de Nadai Bart Staels David Dombrowicz Anne Tsicopoulos

J Allergy Clin Immunol 2016 11 4;138(5):1309-1318.e11. Epub 2016 Apr 4.

Institut National de la Santé Et de la Recherche Médicale U1019, Lille, France; CNRS UMR 8204, Center for Infection and Immunity of Lille, Pulmonary Immunity Team, Lille, France; Institut Pasteur de Lille, Lille, France; Université de Lille, Lille, France; Clinique des Maladies Respiratoires et Centre Hospitalier Régional et Universitaire de Lille, Lille, France. Electronic address:

November 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Authors:

Daniel J Klionsky Kotb Abdelmohsen Akihisa Abe Md Joynal Abedin Hagai Abeliovich Abraham Acevedo Arozena Hiroaki Adachi Christopher M Adams Peter D Adams Khosrow Adeli Peter J Adhihetty Sharon G Adler Galila Agam Rajesh Agarwal Manish K Aghi Maria Agnello Patrizia Agostinis Patricia V Aguilar Julio Aguirre-Ghiso Edoardo M Airoldi Slimane Ait-Si-Ali Takahiko Akematsu Emmanuel T Akporiaye Mohamed Al-Rubeai Guillermo M Albaiceta Chris Albanese Diego Albani Matthew L Albert Jesus Aldudo Hana Algül Mehrdad Alirezaei Iraide Alloza Alexandru Almasan Maylin Almonte-Beceril Emad S Alnemri Covadonga Alonso Nihal Altan-Bonnet Dario C Altieri Silvia Alvarez Lydia Alvarez-Erviti Sandro Alves Giuseppina Amadoro Atsuo Amano Consuelo Amantini Santiago Ambrosio Ivano Amelio Amal O Amer Mohamed Amessou Angelika Amon Zhenyi An Frank A Anania Stig U Andersen Usha P Andley Catherine K Andreadi Nathalie Andrieu-Abadie Alberto Anel David K Ann Shailendra Anoopkumar-Dukie Manuela Antonioli Hiroshi Aoki Nadezda Apostolova Saveria Aquila Katia Aquilano Koichi Araki Eli Arama Agustin Aranda Jun Araya Alexandre Arcaro Esperanza Arias Hirokazu Arimoto Aileen R Ariosa Jane L Armstrong Thierry Arnould Ivica Arsov Katsuhiko Asanuma Valerie Askanas Eric Asselin Ryuichiro Atarashi Sally S Atherton Julie D Atkin Laura D Attardi Patrick Auberger Georg Auburger Laure Aurelian Riccardo Autelli Laura Avagliano Maria Laura Avantaggiati Limor Avrahami Suresh Awale Neelam Azad Tiziana Bachetti Jonathan M Backer Dong-Hun Bae Jae-Sung Bae Ok-Nam Bae Soo Han Bae Eric H Baehrecke Seung-Hoon Baek Stephen Baghdiguian Agnieszka Bagniewska-Zadworna Hua Bai Jie Bai Xue-Yuan Bai Yannick Bailly Kithiganahalli Narayanaswamy Balaji Walter Balduini Andrea Ballabio Rena Balzan Rajkumar Banerjee Gábor Bánhegyi Haijun Bao Benoit Barbeau Maria D Barrachina Esther Barreiro Bonnie Bartel Alberto Bartolomé Diane C Bassham Maria Teresa Bassi Robert C Bast Alakananda Basu Maria Teresa Batista Henri Batoko Maurizio Battino Kyle Bauckman Bradley L Baumgarner K Ulrich Bayer Rupert Beale Jean-François Beaulieu George R Beck Christoph Becker J David Beckham Pierre-André Bédard Patrick J Bednarski Thomas J Begley Christian Behl Christian Behrends Georg Mn Behrens Kevin E Behrns Eloy Bejarano Amine Belaid Francesca Belleudi Giovanni Bénard Guy Berchem Daniele Bergamaschi Matteo Bergami Ben Berkhout Laura Berliocchi Amélie Bernard Monique Bernard Francesca Bernassola Anne Bertolotti Amanda S Bess Sébastien Besteiro Saverio Bettuzzi Savita Bhalla Shalmoli Bhattacharyya Sujit K Bhutia Caroline Biagosch Michele Wolfe Bianchi Martine Biard-Piechaczyk Viktor Billes Claudia Bincoletto Baris Bingol Sara W Bird Marc Bitoun Ivana Bjedov Craig Blackstone Lionel Blanc Guillermo A Blanco Heidi Kiil Blomhoff Emilio Boada-Romero Stefan Böckler Marianne Boes Kathleen Boesze-Battaglia Lawrence H Boise Alessandra Bolino Andrea Boman Paolo Bonaldo Matteo Bordi Jürgen Bosch Luis M Botana Joelle Botti German Bou Marina Bouché Marion Bouchecareilh Marie-Josée Boucher Michael E Boulton Sebastien G Bouret Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan Brady Vania Mm Braga Claudio Brancolini Gerhard H Braus José M Bravo-San Pedro Lisa A Brennan Emery H Bresnick Patrick Brest Dave Bridges Marie-Agnès Bringer Marisa Brini Glauber C Brito Bertha Brodin Paul S Brookes Eric J Brown Karen Brown Hal E Broxmeyer Alain Bruhat Patricia Chakur Brum John H Brumell Nicola Brunetti-Pierri Robert J Bryson-Richardson Shilpa Buch Alastair M Buchan Hikmet Budak Dmitry V Bulavin Scott J Bultman Geert Bultynck Vladimir Bumbasirevic Yan Burelle Robert E Burke Margit Burmeister Peter Bütikofer Laura Caberlotto Ken Cadwell Monika Cahova Dongsheng Cai Jingjing Cai Qian Cai Sara Calatayud Nadine Camougrand Michelangelo Campanella Grant R Campbell Matthew Campbell Silvia Campello Robin Candau Isabella Caniggia Lavinia Cantoni Lizhi Cao Allan B Caplan Michele Caraglia Claudio Cardinali Sandra Morais Cardoso Jennifer S Carew Laura A Carleton Cathleen R Carlin Silvia Carloni Sven R Carlsson Didac Carmona-Gutierrez Leticia Am Carneiro Oliana Carnevali Serena Carra Alice Carrier Bernadette Carroll Caty Casas Josefina Casas Giuliana Cassinelli Perrine Castets Susana Castro-Obregon Gabriella Cavallini Isabella Ceccherini Francesco Cecconi Arthur I Cederbaum Valentín Ceña Simone Cenci Claudia Cerella Davide Cervia Silvia Cetrullo Hassan Chaachouay Han-Jung Chae Andrei S Chagin Chee-Yin Chai Gopal Chakrabarti Georgios Chamilos Edmond Yw Chan Matthew Tv Chan Dhyan Chandra Pallavi Chandra Chih-Peng Chang Raymond Chuen-Chung Chang Ta Yuan Chang John C Chatham Saurabh Chatterjee Santosh Chauhan Yongsheng Che Michael E Cheetham Rajkumar Cheluvappa Chun-Jung Chen Gang Chen Guang-Chao Chen Guoqiang Chen Hongzhuan Chen Jeff W Chen Jian-Kang Chen Min Chen Mingzhou Chen Peiwen Chen Qi Chen Quan Chen Shang-Der Chen Si Chen Steve S-L Chen Wei Chen Wei-Jung Chen Wen Qiang Chen Wenli Chen Xiangmei Chen Yau-Hung Chen Ye-Guang Chen Yin Chen Yingyu Chen Yongshun Chen Yu-Jen Chen Yue-Qin Chen Yujie Chen Zhen Chen Zhong Chen Alan Cheng Christopher Hk Cheng Hua Cheng Heesun Cheong Sara Cherry Jason Chesney Chun Hei Antonio Cheung Eric Chevet Hsiang Cheng Chi Sung-Gil Chi Fulvio Chiacchiera Hui-Ling Chiang Roberto Chiarelli Mario Chiariello Marcello Chieppa Lih-Shen Chin Mario Chiong Gigi Nc Chiu Dong-Hyung Cho Ssang-Goo Cho William C Cho Yong-Yeon Cho Young-Seok Cho Augustine Mk Choi Eui-Ju Choi Eun-Kyoung Choi Jayoung Choi Mary E Choi Seung-Il Choi Tsui-Fen Chou Salem Chouaib Divaker Choubey Vinay Choubey Kuan-Chih Chow Kamal Chowdhury Charleen T Chu Tsung-Hsien Chuang Taehoon Chun Hyewon Chung Taijoon Chung Yuen-Li Chung Yong-Joon Chwae Valentina Cianfanelli Roberto Ciarcia Iwona A Ciechomska Maria Rosa Ciriolo Mara Cirone Sofie Claerhout Michael J Clague Joan Clària Peter Gh Clarke Robert Clarke Emilio Clementi Cédric Cleyrat Miriam Cnop Eliana M Coccia Tiziana Cocco Patrice Codogno Jörn Coers Ezra Ew Cohen David Colecchia Luisa Coletto Núria S Coll Emma Colucci-Guyon Sergio Comincini Maria Condello Katherine L Cook Graham H Coombs Cynthia D Cooper J Mark Cooper Isabelle Coppens Maria Tiziana Corasaniti Marco Corazzari Ramon Corbalan Elisabeth Corcelle-Termeau Mario D Cordero Cristina Corral-Ramos Olga Corti Andrea Cossarizza Paola Costelli Safia Costes Susan L Cotman Ana Coto-Montes Sandra Cottet Eduardo Couve Lori R Covey L Ashley Cowart Jeffery S Cox Fraser P Coxon Carolyn B Coyne Mark S Cragg Rolf J Craven Tiziana Crepaldi Jose L Crespo Alfredo Criollo Valeria Crippa Maria Teresa Cruz Ana Maria Cuervo Jose M Cuezva Taixing Cui Pedro R Cutillas Mark J Czaja Maria F Czyzyk-Krzeska Ruben K Dagda Uta Dahmen Chunsun Dai Wenjie Dai Yun Dai Kevin N Dalby Luisa Dalla Valle Guillaume Dalmasso Marcello D'Amelio Markus Damme Arlette Darfeuille-Michaud Catherine Dargemont Victor M Darley-Usmar Srinivasan Dasarathy Biplab Dasgupta Srikanta Dash Crispin R Dass Hazel Marie Davey Lester M Davids David Dávila Roger J Davis Ted M Dawson Valina L Dawson Paula Daza Jackie de Belleroche Paul de Figueiredo Regina Celia Bressan Queiroz de Figueiredo José de la Fuente Luisa De Martino Antonella De Matteis Guido Ry De Meyer Angelo De Milito Mauro De Santi Wanderley de Souza Vincenzo De Tata Daniela De Zio Jayanta Debnath Reinhard Dechant Jean-Paul Decuypere Shane Deegan Benjamin Dehay Barbara Del Bello Dominic P Del Re Régis Delage-Mourroux Lea Md Delbridge Louise Deldicque Elizabeth Delorme-Axford Yizhen Deng Joern Dengjel Melanie Denizot Paul Dent Channing J Der Vojo Deretic Benoît Derrien Eric Deutsch Timothy P Devarenne Rodney J Devenish Sabrina Di Bartolomeo Nicola Di Daniele Fabio Di Domenico Alessia Di Nardo Simone Di Paola Antonio Di Pietro Livia Di Renzo Aaron DiAntonio Guillermo Díaz-Araya Ines Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Chad A Dickey Robert C Dickson Marc Diederich Paul Digard Ivan Dikic Savithrama P Dinesh-Kumar Chan Ding Wen-Xing Ding Zufeng Ding Luciana Dini Jörg Hw Distler Abhinav Diwan Mojgan Djavaheri-Mergny Kostyantyn Dmytruk Renwick Cj Dobson Volker Doetsch Karol Dokladny Svetlana Dokudovskaya Massimo Donadelli X Charlie Dong Xiaonan Dong Zheng Dong Terrence M Donohue Kelly S Doran Gabriella D'Orazi Gerald W Dorn Victor Dosenko Sami Dridi Liat Drucker Jie Du Li-Lin Du Lihuan Du André du Toit Priyamvada Dua Lei Duan Pu Duann Vikash Kumar Dubey Michael R Duchen Michel A Duchosal Helene Duez Isabelle Dugail Verónica I Dumit Mara C Duncan Elaine A Dunlop William A Dunn Nicolas Dupont Luc Dupuis Raúl V Durán Thomas M Durcan Stéphane Duvezin-Caubet Umamaheswar Duvvuri Vinay Eapen Darius Ebrahimi-Fakhari Arnaud Echard Leopold Eckhart Charles L Edelstein Aimee L Edinger Ludwig Eichinger Tobias Eisenberg Avital Eisenberg-Lerner N Tony Eissa Wafik S El-Deiry Victoria El-Khoury Zvulun Elazar Hagit Eldar-Finkelman Chris Jh Elliott Enzo Emanuele Urban Emmenegger Nikolai Engedal Anna-Mart Engelbrecht Simone Engelender Jorrit M Enserink Ralf Erdmann Jekaterina Erenpreisa Rajaraman Eri Jason L Eriksen Andreja Erman Ricardo Escalante Eeva-Liisa Eskelinen Lucile Espert Lorena Esteban-Martínez Thomas J Evans Mario Fabri Gemma Fabrias Cinzia Fabrizi Antonio Facchiano Nils J Færgeman Alberto Faggioni W Douglas Fairlie Chunhai Fan Daping Fan Jie Fan Shengyun Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Mathias Faure Francois B Favier Howard Fearnhead Massimo Federici Erkang Fei Tania C Felizardo Hua Feng Yibin Feng Yuchen Feng Thomas A Ferguson Álvaro F Fernández Maite G Fernandez-Barrena Jose C Fernandez-Checa Arsenio Fernández-López Martin E Fernandez-Zapico Olivier Feron Elisabetta Ferraro Carmen Veríssima Ferreira-Halder Laszlo Fesus Ralph Feuer Fabienne C Fiesel Eduardo C Filippi-Chiela Giuseppe Filomeni Gian Maria Fimia John H Fingert Steven Finkbeiner Toren Finkel Filomena Fiorito Paul B Fisher Marc Flajolet Flavio Flamigni Oliver Florey Salvatore Florio R Andres Floto Marco Folini Carlo Follo Edward A Fon Francesco Fornai Franco Fortunato Alessandro Fraldi Rodrigo Franco Arnaud Francois Aurélie François Lisa B Frankel Iain Dc Fraser Norbert Frey Damien G Freyssenet Christian Frezza Scott L Friedman Daniel E Frigo Dongxu Fu José M Fuentes Juan Fueyo Yoshio Fujitani Yuuki Fujiwara Mikihiro Fujiya Mitsunori Fukuda Simone Fulda Carmela Fusco Bozena Gabryel Matthias Gaestel Philippe Gailly Malgorzata Gajewska Sehamuddin Galadari Gad Galili Inmaculada Galindo Maria F Galindo Giovanna Galliciotti Lorenzo Galluzzi Luca Galluzzi Vincent Galy Noor Gammoh Sam Gandy Anand K Ganesan Swamynathan Ganesan Ian G Ganley Monique Gannagé Fen-Biao Gao Feng Gao Jian-Xin Gao Lorena García Nannig Eleonora García Véscovi Marina Garcia-Macía Carmen Garcia-Ruiz Abhishek D Garg Pramod Kumar Garg Ricardo Gargini Nils Christian Gassen Damián Gatica Evelina Gatti Julie Gavard Evripidis Gavathiotis Liang Ge Pengfei Ge Shengfang Ge Po-Wu Gean Vania Gelmetti Armando A Genazzani Jiefei Geng Pascal Genschik Lisa Gerner Jason E Gestwicki David A Gewirtz Saeid Ghavami Eric Ghigo Debabrata Ghosh Anna Maria Giammarioli Francesca Giampieri Claudia Giampietri Alexandra Giatromanolaki Derrick J Gibbings Lara Gibellini Spencer B Gibson Vanessa Ginet Antonio Giordano Flaviano Giorgini Elisa Giovannetti Stephen E Girardin Suzana Gispert Sandy Giuliano Candece L Gladson Alvaro Glavic Martin Gleave Nelly Godefroy Robert M Gogal Kuppan Gokulan Gustavo H Goldman Delia Goletti Michael S Goligorsky Aldrin V Gomes Ligia C Gomes Hernando Gomez Candelaria Gomez-Manzano Rubén Gómez-Sánchez Dawit Ap Gonçalves Ebru Goncu Qingqiu Gong Céline Gongora Carlos B Gonzalez Pedro Gonzalez-Alegre Pilar Gonzalez-Cabo Rosa Ana González-Polo Ing Swie Goping Carlos Gorbea Nikolai V Gorbunov Daphne R Goring Adrienne M Gorman Sharon M Gorski Sandro Goruppi Shino Goto-Yamada Cecilia Gotor Roberta A Gottlieb Illana Gozes Devrim Gozuacik Yacine Graba Martin Graef Giovanna E Granato Gary Dean Grant Steven Grant Giovanni Luca Gravina Douglas R Green Alexander Greenhough Michael T Greenwood Benedetto Grimaldi Frédéric Gros Charles Grose Jean-Francois Groulx Florian Gruber Paolo Grumati Tilman Grune Jun-Lin Guan Kun-Liang Guan Barbara Guerra Carlos Guillen Kailash Gulshan Jan Gunst Chuanyong Guo Lei Guo Ming Guo Wenjie Guo Xu-Guang Guo Andrea A Gust Åsa B Gustafsson Elaine Gutierrez Maximiliano G Gutierrez Ho-Shin Gwak Albert Haas James E Haber Shinji Hadano Monica Hagedorn David R Hahn Andrew J Halayko Anne Hamacher-Brady Kozo Hamada Ahmed Hamai Andrea Hamann Maho Hamasaki Isabelle Hamer Qutayba Hamid Ester M Hammond Feng Han Weidong Han James T Handa John A Hanover Malene Hansen Masaru Harada Ljubica Harhaji-Trajkovic J Wade Harper Abdel Halim Harrath Adrian L Harris James Harris Udo Hasler Peter Hasselblatt Kazuhisa Hasui Robert G Hawley Teresa S Hawley Congcong He Cynthia Y He Fengtian He Gu He Rong-Rong He Xian-Hui He You-Wen He Yu-Ying He Joan K Heath Marie-Josée Hébert Robert A Heinzen Gudmundur Vignir Helgason Michael Hensel Elizabeth P Henske Chengtao Her Paul K Herman Agustín Hernández Carlos Hernandez Sonia Hernández-Tiedra Claudio Hetz P Robin Hiesinger Katsumi Higaki Sabine Hilfiker Bradford G Hill Joseph A Hill William D Hill Keisuke Hino Daniel Hofius Paul Hofman Günter U Höglinger Jörg Höhfeld Marina K Holz Yonggeun Hong David A Hood Jeroen Jm Hoozemans Thorsten Hoppe Chin Hsu Chin-Yuan Hsu Li-Chung Hsu Dong Hu Guochang Hu Hong-Ming Hu Hongbo Hu Ming Chang Hu Yu-Chen Hu Zhuo-Wei Hu Fang Hua Ya Hua Canhua Huang Huey-Lan Huang Kuo-How Huang Kuo-Yang Huang Shile Huang Shiqian Huang Wei-Pang Huang Yi-Ran Huang Yong Huang Yunfei Huang Tobias B Huber Patricia Huebbe Won-Ki Huh Juha J Hulmi Gang Min Hur James H Hurley Zvenyslava Husak Sabah Na Hussain Salik Hussain Jung Jin Hwang Seungmin Hwang Thomas Is Hwang Atsuhiro Ichihara Yuzuru Imai Carol Imbriano Megumi Inomata Takeshi Into Valentina Iovane Juan L Iovanna Renato V Iozzo Nancy Y Ip Javier E Irazoqui Pablo Iribarren Yoshitaka Isaka Aleksandra J Isakovic Harry Ischiropoulos Jeffrey S Isenberg Mohammad Ishaq Hiroyuki Ishida Isao Ishii Jane E Ishmael Ciro Isidoro Ken-Ichi Isobe Erika Isono Shohreh Issazadeh-Navikas Koji Itahana Eisuke Itakura Andrei I Ivanov Anand Krishnan V Iyer José M Izquierdo Yotaro Izumi Valentina Izzo Marja Jäättelä Nadia Jaber Daniel John Jackson William T Jackson Tony George Jacob Thomas S Jacques Chinnaswamy Jagannath Ashish Jain Nihar Ranjan Jana Byoung Kuk Jang Alkesh Jani Bassam Janji Paulo Roberto Jannig Patric J Jansson Steve Jean Marina Jendrach Ju-Hong Jeon Niels Jessen Eui-Bae Jeung Kailiang Jia Lijun Jia Hong Jiang Hongchi Jiang Liwen Jiang Teng Jiang Xiaoyan Jiang Xuejun Jiang Xuejun Jiang Ying Jiang Yongjun Jiang Alberto Jiménez Cheng Jin Hongchuan Jin Lei Jin Meiyan Jin Shengkan Jin Umesh Kumar Jinwal Eun-Kyeong Jo Terje Johansen Daniel E Johnson Gail Vw Johnson James D Johnson Eric Jonasch Chris Jones Leo Ab Joosten Joaquin Jordan Anna-Maria Joseph Bertrand Joseph Annie M Joubert Dianwen Ju Jingfang Ju Hsueh-Fen Juan Katrin Juenemann Gábor Juhász Hye Seung Jung Jae U Jung Yong-Keun Jung Heinz Jungbluth Matthew J Justice Barry Jutten Nadeem O Kaakoush Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Bertrand Kaeffer Katarina Kågedal Alon Kahana Shingo Kajimura Or Kakhlon Manjula Kalia Dhan V Kalvakolanu Yoshiaki Kamada Konstantinos Kambas Vitaliy O Kaminskyy Harm H Kampinga Mustapha Kandouz Chanhee Kang Rui Kang Tae-Cheon Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Marc Kantorow Maria Kaparakis-Liaskos Orsolya Kapuy Vassiliki Karantza Md Razaul Karim Parimal Karmakar Arthur Kaser Susmita Kaushik Thomas Kawula A Murat Kaynar Po-Yuan Ke Zun-Ji Ke John H Kehrl Kate E Keller Jongsook Kim Kemper Anne K Kenworthy Oliver Kepp Andreas Kern Santosh Kesari David Kessel Robin Ketteler Isis do Carmo Kettelhut Bilon Khambu Muzamil Majid Khan Vinoth Km Khandelwal Sangeeta Khare Juliann G Kiang Amy A Kiger Akio Kihara Arianna L Kim Cheol Hyeon Kim Deok Ryong Kim Do-Hyung Kim Eung Kweon Kim Hye Young Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim Jin Hyoung Kim Kwang Woon Kim Michael D Kim Moon-Moo Kim Peter K Kim Seong Who Kim Soo-Youl Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Tomonori Kimura Jason S King Karla Kirkegaard Vladimir Kirkin Lorrie A Kirshenbaum Shuji Kishi Yasuo Kitajima Katsuhiko Kitamoto Yasushi Kitaoka Kaio Kitazato Rudolf A Kley Walter T Klimecki Michael Klinkenberg Jochen Klucken Helene Knævelsrud Erwin Knecht Laura Knuppertz Jiunn-Liang Ko Satoru Kobayashi Jan C Koch Christelle Koechlin-Ramonatxo Ulrich Koenig Young Ho Koh Katja Köhler Sepp D Kohlwein Masato Koike Masaaki Komatsu Eiki Kominami Dexin Kong Hee Jeong Kong Eumorphia G Konstantakou Benjamin T Kopp Tamas Korcsmaros Laura Korhonen Viktor I Korolchuk Nadya V Koshkina Yanjun Kou Michael I Koukourakis Constantinos Koumenis Attila L Kovács Tibor Kovács Werner J Kovacs Daisuke Koya Claudine Kraft Dimitri Krainc Helmut Kramer Tamara Kravic-Stevovic Wilhelm Krek Carole Kretz-Remy Roswitha Krick Malathi Krishnamurthy Janos Kriston-Vizi Guido Kroemer Michael C Kruer Rejko Kruger Nicholas T Ktistakis Kazuyuki Kuchitsu Christian Kuhn Addanki Pratap Kumar Anuj Kumar Ashok Kumar Deepak Kumar Dhiraj Kumar Rakesh Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Atsushi Kuno Sheng-Han Kuo Jeff Kuret Tino Kurz Terry Kwok Taeg Kyu Kwon Yong Tae Kwon Irene Kyrmizi Albert R La Spada Frank Lafont Tim Lahm Aparna Lakkaraju Truong Lam Trond Lamark Steve Lancel Terry H Landowski Darius J R Lane Jon D Lane Cinzia Lanzi Pierre Lapaquette Louis R Lapierre Jocelyn Laporte Johanna Laukkarinen Gordon W Laurie Sergio Lavandero Lena Lavie Matthew J LaVoie Betty Yuen Kwan Law Helen Ka-Wai Law Kelsey B Law Robert Layfield Pedro A Lazo Laurent Le Cam Karine G Le Roch Hervé Le Stunff Vijittra Leardkamolkarn Marc Lecuit Byung-Hoon Lee Che-Hsin Lee Erinna F Lee Gyun Min Lee He-Jin Lee Hsinyu Lee Jae Keun Lee Jongdae Lee Ju-Hyun Lee Jun Hee Lee Michael Lee Myung-Shik Lee Patty J Lee Sam W Lee Seung-Jae Lee Shiow-Ju Lee Stella Y Lee Sug Hyung Lee Sung Sik Lee Sung-Joon Lee Sunhee Lee Ying-Ray Lee Yong J Lee Young H Lee Christiaan Leeuwenburgh Sylvain Lefort Renaud Legouis Jinzhi Lei Qun-Ying Lei David A Leib Gil Leibowitz Istvan Lekli Stéphane D Lemaire John J Lemasters Marius K Lemberg Antoinette Lemoine Shuilong Leng Guido Lenz Paola Lenzi Lilach O Lerman Daniele Lettieri Barbato Julia I-Ju Leu Hing Y Leung Beth Levine Patrick A Lewis Frank Lezoualc'h Chi Li Faqiang Li Feng-Jun Li Jun Li Ke Li Lian Li Min Li Min Li Qiang Li Rui Li Sheng Li Wei Li Wei Li Xiaotao Li Yumin Li Jiqin Lian Chengyu Liang Qiangrong Liang Yulin Liao Joana Liberal Pawel P Liberski Pearl Lie Andrew P Lieberman Hyunjung Jade Lim Kah-Leong Lim Kyu Lim Raquel T Lima Chang-Shen Lin Chiou-Feng Lin Fang Lin Fangming Lin Fu-Cheng Lin Kui Lin Kwang-Huei Lin Pei-Hui Lin Tianwei Lin Wan-Wan Lin Yee-Shin Lin Yong Lin Rafael Linden Dan Lindholm Lisa M Lindqvist Paul Lingor Andreas Linkermann Lance A Liotta Marta M Lipinski Vitor A Lira Michael P Lisanti Paloma B Liton Bo Liu Chong Liu Chun-Feng Liu Fei Liu Hung-Jen Liu Jianxun Liu Jing-Jing Liu Jing-Lan Liu Ke Liu Leyuan Liu Liang Liu Quentin Liu Rong-Yu Liu Shiming Liu Shuwen Liu Wei Liu Xian-De Liu Xiangguo Liu Xiao-Hong Liu Xinfeng Liu Xu Liu Xueqin Liu Yang Liu Yule Liu Zexian Liu Zhe Liu Juan P Liuzzi Gérard Lizard Mila Ljujic Irfan J Lodhi Susan E Logue Bal L Lokeshwar Yun Chau Long Sagar Lonial Benjamin Loos Carlos López-Otín Cristina López-Vicario Mar Lorente Philip L Lorenzi Péter Lõrincz Marek Los Michael T Lotze Penny E Lovat Binfeng Lu Bo Lu Jiahong Lu Qing Lu She-Min Lu Shuyan Lu Yingying Lu Frédéric Luciano Shirley Luckhart John Milton Lucocq Paula Ludovico Aurelia Lugea Nicholas W Lukacs Julian J Lum Anders H Lund Honglin Luo Jia Luo Shouqing Luo Claudio Luparello Timothy Lyons Jianjie Ma Yi Ma Yong Ma Zhenyi Ma Juliano Machado Glaucia M Machado-Santelli Fernando Macian Gustavo C MacIntosh Jeffrey P MacKeigan Kay F Macleod John D MacMicking Lee Ann MacMillan-Crow Frank Madeo Muniswamy Madesh Julio Madrigal-Matute Akiko Maeda Tatsuya Maeda Gustavo Maegawa Emilia Maellaro Hannelore Maes Marta Magariños Kenneth Maiese Tapas K Maiti Luigi Maiuri Maria Chiara Maiuri Carl G Maki Roland Malli Walter Malorni Alina Maloyan Fathia Mami-Chouaib Na Man Joseph D Mancias Eva-Maria Mandelkow Michael A Mandell Angelo A Manfredi Serge N Manié Claudia Manzoni Kai Mao Zixu Mao Zong-Wan Mao Philippe Marambaud Anna Maria Marconi Zvonimir Marelja Gabriella Marfe Marta Margeta Eva Margittai Muriel Mari Francesca V Mariani Concepcio Marin Sara Marinelli Guillermo Mariño Ivanka Markovic Rebecca Marquez Alberto M Martelli Sascha Martens Katie R Martin Seamus J Martin Shaun Martin Miguel A Martin-Acebes Paloma Martín-Sanz Camille Martinand-Mari Wim Martinet Jennifer Martinez Nuria Martinez-Lopez Ubaldo Martinez-Outschoorn Moisés Martínez-Velázquez Marta Martinez-Vicente Waleska Kerllen Martins Hirosato Mashima James A Mastrianni Giuseppe Matarese Paola Matarrese Roberto Mateo Satoaki Matoba Naomichi Matsumoto Takehiko Matsushita Akira Matsuura Takeshi Matsuzawa Mark P Mattson Soledad Matus Norma Maugeri Caroline Mauvezin Andreas Mayer Dusica Maysinger Guillermo D Mazzolini Mary Kate McBrayer Kimberly McCall Craig McCormick Gerald M McInerney Skye C McIver Sharon McKenna John J McMahon Iain A McNeish Fatima Mechta-Grigoriou Jan Paul Medema Diego L Medina Klara Megyeri Maryam Mehrpour Jawahar L Mehta Yide Mei Ute-Christiane Meier Alfred J Meijer Alicia Meléndez Gerry Melino Sonia Melino Edesio Jose Tenorio de Melo Maria A Mena Marc D Meneghini Javier A Menendez Regina Menezes Liesu Meng Ling-Hua Meng Songshu Meng Rossella Menghini A Sue Menko Rubem Fs Menna-Barreto Manoj B Menon Marco A Meraz-Ríos Giuseppe Merla Luciano Merlini Angelica M Merlot Andreas Meryk Stefania Meschini Joel N Meyer Man-Tian Mi Chao-Yu Miao Lucia Micale Simon Michaeli Carine Michiels Anna Rita Migliaccio Anastasia Susie Mihailidou Dalibor Mijaljica Katsuhiko Mikoshiba Enrico Milan Leonor Miller-Fleming Gordon B Mills Ian G Mills Georgia Minakaki Berge A Minassian Xiu-Fen Ming Farida Minibayeva Elena A Minina Justine D Mintern Saverio Minucci Antonio Miranda-Vizuete Claire H Mitchell Shigeki Miyamoto Keisuke Miyazawa Noboru Mizushima Katarzyna Mnich Baharia Mograbi Simin Mohseni Luis Ferreira Moita Marco Molinari Maurizio Molinari Andreas Buch Møller Bertrand Mollereau Faustino Mollinedo Marco Mongillo Martha M Monick Serena Montagnaro Craig Montell Darren J Moore Michael N Moore Rodrigo Mora-Rodriguez Paula I Moreira Etienne Morel Maria Beatrice Morelli Sandra Moreno Michael J Morgan Arnaud Moris Yuji Moriyasu Janna L Morrison Lynda A Morrison Eugenia Morselli Jorge Moscat Pope L Moseley Serge Mostowy Elisa Motori Denis Mottet Jeremy C Mottram Charbel E-H Moussa Vassiliki E Mpakou Hasan Mukhtar Jean M Mulcahy Levy Sylviane Muller Raquel Muñoz-Moreno Cristina Muñoz-Pinedo Christian Münz Maureen E Murphy James T Murray Aditya Murthy Indira U Mysorekar Ivan R Nabi Massimo Nabissi Gustavo A Nader Yukitoshi Nagahara Yoshitaka Nagai Kazuhiro Nagata Anika Nagelkerke Péter Nagy Samisubbu R Naidu Sreejayan Nair Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Gennaro Napolitano Naweed I Naqvi Roberta Nardacci Derek P Narendra Masashi Narita Anna Chiara Nascimbeni Ramesh Natarajan Luiz C Navegantes Steffan T Nawrocki Taras Y Nazarko Volodymyr Y Nazarko Thomas Neill Luca M Neri Mihai G Netea Romana T Netea-Maier Bruno M Neves Paul A Ney Ioannis P Nezis Hang Tt Nguyen Huu Phuc Nguyen Anne-Sophie Nicot Hilde Nilsen Per Nilsson Mikio Nishimura Ichizo Nishino Mireia Niso-Santano Hua Niu Ralph A Nixon Vincent Co Njar Takeshi Noda Angelika A Noegel Elsie Magdalena Nolte Erik Norberg Koenraad K Norga Sakineh Kazemi Noureini Shoji Notomi Lucia Notterpek Karin Nowikovsky Nobuyuki Nukina Thorsten Nürnberger Valerie B O'Donnell Tracey O'Donovan Peter J O'Dwyer Ina Oehme Clara L Oeste Michinaga Ogawa Besim Ogretmen Yuji Ogura Young J Oh Masaki Ohmuraya Takayuki Ohshima Rani Ojha Koji Okamoto Toshiro Okazaki F Javier Oliver Karin Ollinger Stefan Olsson Daniel P Orban Paulina Ordonez Idil Orhon Laszlo Orosz Eyleen J O'Rourke Helena Orozco Angel L Ortega Elena Ortona Laura D Osellame Junko Oshima Shigeru Oshima Heinz D Osiewacz Takanobu Otomo Kinya Otsu Jing-Hsiung James Ou Tiago F Outeiro Dong-Yun Ouyang Hongjiao Ouyang Michael Overholtzer Michelle A Ozbun P Hande Ozdinler Bulent Ozpolat Consiglia Pacelli Paolo Paganetti Guylène Page Gilles Pages Ugo Pagnini Beata Pajak Stephen C Pak Karolina Pakos-Zebrucka Nazzy Pakpour Zdena Palková Francesca Palladino Kathrin Pallauf Nicolas Pallet Marta Palmieri Søren R Paludan Camilla Palumbo Silvia Palumbo Olatz Pampliega Hongming Pan Wei Pan Theocharis Panaretakis Aseem Pandey Areti Pantazopoulou Zuzana Papackova Daniela L Papademetrio Issidora Papassideri Alessio Papini Nirmala Parajuli Julian Pardo Vrajesh V Parekh Giancarlo Parenti Jong-In Park Junsoo Park Ohkmae K Park Roy Parker Rosanna Parlato Jan B Parys Katherine R Parzych Jean-Max Pasquet Benoit Pasquier Kishore Bs Pasumarthi Daniel Patschan Cam Patterson Sophie Pattingre Scott Pattison Arnim Pause Hermann Pavenstädt Flaminia Pavone Zully Pedrozo Fernando J Peña Miguel A Peñalva Mario Pende Jianxin Peng Fabio Penna Josef M Penninger Anna Pensalfini Salvatore Pepe Gustavo Js Pereira Paulo C Pereira Verónica Pérez-de la Cruz María Esther Pérez-Pérez Diego Pérez-Rodríguez Dolores Pérez-Sala Celine Perier Andras Perl David H Perlmutter Ida Perrotta Shazib Pervaiz Maija Pesonen Jeffrey E Pessin Godefridus J Peters Morten Petersen Irina Petrache Basil J Petrof Goran Petrovski James M Phang Mauro Piacentini Marina Pierdominici Philippe Pierre Valérie Pierrefite-Carle Federico Pietrocola Felipe X Pimentel-Muiños Mario Pinar Benjamin Pineda Ronit Pinkas-Kramarski Marcello Pinti Paolo Pinton Bilal Piperdi James M Piret Leonidas C Platanias Harald W Platta Edward D Plowey Stefanie Pöggeler Marc Poirot Peter Polčic Angelo Poletti Audrey H Poon Hana Popelka Blagovesta Popova Izabela Poprawa Shibu M Poulose Joanna Poulton Scott K Powers Ted Powers Mercedes Pozuelo-Rubio Krisna Prak Reinhild Prange Mark Prescott Muriel Priault Sharon Prince Richard L Proia Tassula Proikas-Cezanne Holger Prokisch Vasilis J Promponas Karin Przyklenk Rosa Puertollano Subbiah Pugazhenthi Luigi Puglielli Aurora Pujol Julien Puyal Dohun Pyeon Xin Qi Wen-Bin Qian Zheng-Hong Qin Yu Qiu Ziwei Qu Joe Quadrilatero Frederick Quinn Nina Raben Hannah Rabinowich Flavia Radogna Michael J Ragusa Mohamed Rahmani Komal Raina Sasanka Ramanadham Rajagopal Ramesh Abdelhaq Rami Sarron Randall-Demllo Felix Randow Hai Rao V Ashutosh Rao Blake B Rasmussen Tobias M Rasse Edward A Ratovitski Pierre-Emmanuel Rautou Swapan K Ray Babak Razani Bruce H Reed Fulvio Reggiori Markus Rehm Andreas S Reichert Theo Rein David J Reiner Eric Reits Jun Ren Xingcong Ren Maurizio Renna Jane Eb Reusch Jose L Revuelta Leticia Reyes Alireza R Rezaie Robert I Richards Des R Richardson Clémence Richetta Michael A Riehle Bertrand H Rihn Yasuko Rikihisa Brigit E Riley Gerald Rimbach Maria Rita Rippo Konstantinos Ritis Federica Rizzi Elizete Rizzo Peter J Roach Jeffrey Robbins Michel Roberge Gabriela Roca Maria Carmela Roccheri Sonia Rocha Cecilia Mp Rodrigues Clara I Rodríguez Santiago Rodriguez de Cordoba Natalia Rodriguez-Muela Jeroen Roelofs Vladimir V Rogov Troy T Rohn Bärbel Rohrer Davide Romanelli Luigina Romani Patricia Silvia Romano M Isabel G Roncero Jose Luis Rosa Alicia Rosello Kirill V Rosen Philip Rosenstiel Magdalena Rost-Roszkowska Kevin A Roth Gael Roué Mustapha Rouis Kasper M Rouschop Daniel T Ruan Diego Ruano David C Rubinsztein Edmund B Rucker Assaf Rudich Emil Rudolf Ruediger Rudolf Markus A Ruegg Carmen Ruiz-Roldan Avnika Ashok Ruparelia Paola Rusmini David W Russ Gian Luigi Russo Giuseppe Russo Rossella Russo Tor Erik Rusten Victoria Ryabovol Kevin M Ryan Stefan W Ryter David M Sabatini Michael Sacher Carsten Sachse Michael N Sack Junichi Sadoshima Paul Saftig Ronit Sagi-Eisenberg Sumit Sahni Pothana Saikumar Tsunenori Saito Tatsuya Saitoh Koichi Sakakura Machiko Sakoh-Nakatogawa Yasuhito Sakuraba María Salazar-Roa Paolo Salomoni Ashok K Saluja Paul M Salvaterra Rosa Salvioli Afshin Samali Anthony Mj Sanchez José A Sánchez-Alcázar Ricardo Sanchez-Prieto Marco Sandri Miguel A Sanjuan Stefano Santaguida Laura Santambrogio Giorgio Santoni Claudia Nunes Dos Santos Shweta Saran Marco Sardiello Graeme Sargent Pallabi Sarkar Sovan Sarkar Maria Rosa Sarrias Minnie M Sarwal Chihiro Sasakawa Motoko Sasaki Miklos Sass Ken Sato Miyuki Sato Joseph Satriano Niramol Savaraj Svetlana Saveljeva Liliana Schaefer Ulrich E Schaible Michael Scharl Hermann M Schatzl Randy Schekman Wiep Scheper Alfonso Schiavi Hyman M Schipper Hana Schmeisser Jens Schmidt Ingo Schmitz Bianca E Schneider E Marion Schneider Jaime L Schneider Eric A Schon Miriam J Schönenberger Axel H Schönthal Daniel F Schorderet Bernd Schröder Sebastian Schuck Ryan J Schulze Melanie Schwarten Thomas L Schwarz Sebastiano Sciarretta Kathleen Scotto A Ivana Scovassi Robert A Screaton Mark Screen Hugo Seca Simon Sedej Laura Segatori Nava Segev Per O Seglen Jose M Seguí-Simarro Juan Segura-Aguilar Ekihiro Seki Christian Sell Iban Seiliez Clay F Semenkovich Gregg L Semenza Utpal Sen Andreas L Serra Ana Serrano-Puebla Hiromi Sesaki Takao Setoguchi Carmine Settembre John J Shacka Ayesha N Shajahan-Haq Irving M Shapiro Shweta Sharma Hua She C-K James Shen Chiung-Chyi Shen Han-Ming Shen Sanbing Shen Weili Shen Rui Sheng Xianyong Sheng Zu-Hang Sheng Trevor G Shepherd Junyan Shi Qiang Shi Qinghua Shi Yuguang Shi Shusaku Shibutani Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Dong Wook Shin Mari L Shinohara Michiko Shintani Takahiro Shintani Tetsuo Shioi Ken Shirabe Ronit Shiri-Sverdlov Orian Shirihai Gordon C Shore Chih-Wen Shu Deepak Shukla Andriy A Sibirny Valentina Sica Christina J Sigurdson Einar M Sigurdsson Puran Singh Sijwali Beata Sikorska Wilian A Silveira Sandrine Silvente-Poirot Gary A Silverman Jan Simak Thomas Simmet Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Matias Simons Anne Simonsen Rajat Singh Shivendra V Singh Shrawan K Singh Debasish Sinha Sangita Sinha Frank A Sinicrope Agnieszka Sirko Kapil Sirohi Balindiwe Jn Sishi Annie Sittler Parco M Siu Efthimios Sivridis Anna Skwarska Ruth Slack Iva Slaninová Nikolai Slavov Soraya S Smaili Keiran Sm Smalley Duncan R Smith Stefaan J Soenen Scott A Soleimanpour Anita Solhaug Kumaravel Somasundaram Jin H Son Avinash Sonawane Chunjuan Song Fuyong Song Hyun Kyu Song Ju-Xian Song Wei Song Kai Y Soo Anil K Sood Tuck Wah Soong Virawudh Soontornniyomkij Maurizio Sorice Federica Sotgia David R Soto-Pantoja Areechun Sotthibundhu Maria João Sousa Herman P Spaink Paul N Span Anne Spang Janet D Sparks Peter G Speck Stephen A Spector Claudia D Spies Wolfdieter Springer Daret St Clair Alessandra Stacchiotti Bart Staels Michael T Stang Daniel T Starczynowski Petro Starokadomskyy Clemens Steegborn John W Steele Leonidas Stefanis Joan Steffan Christine M Stellrecht Harald Stenmark Tomasz M Stepkowski Stęphan T Stern Craig Stevens Brent R Stockwell Veronika Stoka Zuzana Storchova Björn Stork Vassilis Stratoulias Dimitrios J Stravopodis Pavel Strnad Anne Marie Strohecker Anna-Lena Ström Per Stromhaug Jiri Stulik Yu-Xiong Su Zhaoliang Su Carlos S Subauste Srinivasa Subramaniam Carolyn M Sue Sang Won Suh Xinbing Sui Supawadee Sukseree David Sulzer Fang-Lin Sun Jiaren Sun Jun Sun Shi-Yong Sun Yang Sun Yi Sun Yingjie Sun Vinod Sundaramoorthy Joseph Sung Hidekazu Suzuki Kuninori Suzuki Naoki Suzuki Tadashi Suzuki Yuichiro J Suzuki Michele S Swanson Charles Swanton Karl Swärd Ghanshyam Swarup Sean T Sweeney Paul W Sylvester Zsuzsanna Szatmari Eva Szegezdi Peter W Szlosarek Heinrich Taegtmeyer Marco Tafani Emmanuel Taillebourg Stephen Wg Tait Krisztina Takacs-Vellai Yoshinori Takahashi Szabolcs Takáts Genzou Takemura Nagio Takigawa Nicholas J Talbot Elena Tamagno Jerome Tamburini Cai-Ping Tan Lan Tan Mei Lan Tan Ming Tan Yee-Joo Tan Keiji Tanaka Masaki Tanaka Daolin Tang Dingzhong Tang Guomei Tang Isei Tanida Kunikazu Tanji Bakhos A Tannous Jose A Tapia Inmaculada Tasset-Cuevas Marc Tatar Iman Tavassoly Nektarios Tavernarakis Allen Taylor Graham S Taylor Gregory A Taylor J Paul Taylor Mark J Taylor Elena V Tchetina Andrew R Tee Fatima Teixeira-Clerc Sucheta Telang Tewin Tencomnao Ba-Bie Teng Ru-Jeng Teng Faraj Terro Gianluca Tettamanti Arianne L Theiss Anne E Theron Kelly Jean Thomas Marcos P Thomé Paul G Thomes Andrew Thorburn Jeremy Thorner Thomas Thum Michael Thumm Teresa Lm Thurston Ling Tian Andreas Till Jenny Pan-Yun Ting Vladimir I Titorenko Lilach Toker Stefano Toldo Sharon A Tooze Ivan Topisirovic Maria Lyngaas Torgersen Liliana Torosantucci Alicia Torriglia Maria Rosaria Torrisi Cathy Tournier Roberto Towns Vladimir Trajkovic Leonardo H Travassos Gemma Triola Durga Nand Tripathi Daniela Trisciuoglio Rodrigo Troncoso Ioannis P Trougakos Anita C Truttmann Kuen-Jer Tsai Mario P Tschan Yi-Hsin Tseng Takayuki Tsukuba Allan Tsung Andrey S Tsvetkov Shuiping Tu Hsing-Yu Tuan Marco Tucci David A Tumbarello Boris Turk Vito Turk Robin Fb Turner Anders A Tveita Suresh C Tyagi Makoto Ubukata Yasuo Uchiyama Andrej Udelnow Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Benjamin R Underwood Christian Ungermann Rodrigo P Ureshino Ryo Ushioda Vladimir N Uversky Néstor L Uzcátegui Thomas Vaccari Maria I Vaccaro Libuše Váchová Helin Vakifahmetoglu-Norberg Rut Valdor Enza Maria Valente Francois Vallette Angela M Valverde Greet Van den Berghe Ludo Van Den Bosch Gijs R van den Brink F Gisou van der Goot Ida J van der Klei Luc Jw van der Laan Wouter G van Doorn Marjolein van Egmond Kenneth L van Golen Luc Van Kaer Menno van Lookeren Campagne Peter Vandenabeele Wim Vandenberghe Ilse Vanhorebeek Isabel Varela-Nieto M Helena Vasconcelos Radovan Vasko Demetrios G Vavvas Ignacio Vega-Naredo Guillermo Velasco Athanassios D Velentzas Panagiotis D Velentzas Tibor Vellai Edo Vellenga Mikkel Holm Vendelbo Kartik Venkatachalam Natascia Ventura Salvador Ventura Patrícia St Veras Mireille Verdier Beata G Vertessy Andrea Viale Michel Vidal Helena L A Vieira Richard D Vierstra Nadarajah Vigneswaran Neeraj Vij Miquel Vila Margarita Villar Victor H Villar Joan Villarroya Cécile Vindis Giampietro Viola Maria Teresa Viscomi Giovanni Vitale Dan T Vogl Olga V Voitsekhovskaja Clarissa von Haefen Karin von Schwarzenberg Daniel E Voth Valérie Vouret-Craviari Kristina Vuori Jatin M Vyas Christian Waeber Cheryl Lyn Walker Mark J Walker Jochen Walter Lei Wan Xiangbo Wan Bo Wang Caihong Wang Chao-Yung Wang Chengshu Wang Chenran Wang Chuangui Wang Dong Wang Fen Wang Fuxin Wang Guanghui Wang Hai-Jie Wang Haichao Wang Hong-Gang Wang Hongmin Wang Horng-Dar Wang Jing Wang Junjun Wang Mei Wang Mei-Qing Wang Pei-Yu Wang Peng Wang Richard C Wang Shuo Wang Ting-Fang Wang Xian Wang Xiao-Jia Wang Xiao-Wei Wang Xin Wang Xuejun Wang Yan Wang Yanming Wang Ying Wang Ying-Jan Wang Yipeng Wang Yu Wang Yu Tian Wang Yuqing Wang Zhi-Nong Wang Pablo Wappner Carl Ward Diane McVey Ward Gary Warnes Hirotaka Watada Yoshihisa Watanabe Kei Watase Timothy E Weaver Colin D Weekes Jiwu Wei Thomas Weide Conrad C Weihl Günther Weindl Simone Nardin Weis Longping Wen Xin Wen Yunfei Wen Benedikt Westermann Cornelia M Weyand Anthony R White Eileen White J Lindsay Whitton Alexander J Whitworth Joëlle Wiels Franziska Wild Manon E Wildenberg Tom Wileman Deepti Srinivas Wilkinson Simon Wilkinson Dieter Willbold Chris Williams Katherine Williams Peter R Williamson Konstanze F Winklhofer Steven S Witkin Stephanie E Wohlgemuth Thomas Wollert Ernst J Wolvetang Esther Wong G William Wong Richard W Wong Vincent Kam Wai Wong Elizabeth A Woodcock Karen L Wright Chunlai Wu Defeng Wu Gen Sheng Wu Jian Wu Junfang Wu Mian Wu Min Wu Shengzhou Wu William Kk Wu Yaohua Wu Zhenlong Wu Cristina Pr Xavier Ramnik J Xavier Gui-Xian Xia Tian Xia Weiliang Xia Yong Xia Hengyi Xiao Jian Xiao Shi Xiao Wuhan Xiao Chuan-Ming Xie Zhiping Xie Zhonglin Xie Maria Xilouri Yuyan Xiong Chuanshan Xu Congfeng Xu Feng Xu Haoxing Xu Hongwei Xu Jian Xu Jianzhen Xu Jinxian Xu Liang Xu Xiaolei Xu Yangqing Xu Ye Xu Zhi-Xiang Xu Ziheng Xu Yu Xue Takahiro Yamada Ai Yamamoto Koji Yamanaka Shunhei Yamashina Shigeko Yamashiro Bing Yan Bo Yan Xianghua Yan Zhen Yan Yasuo Yanagi Dun-Sheng Yang Jin-Ming Yang Liu Yang Minghua Yang Pei-Ming Yang Peixin Yang Qian Yang Wannian Yang Wei Yuan Yang Xuesong Yang Yi Yang Ying Yang Zhifen Yang Zhihong Yang Meng-Chao Yao Pamela J Yao Xiaofeng Yao Zhenyu Yao Zhiyuan Yao Linda S Yasui Mingxiang Ye Barry Yedvobnick Behzad Yeganeh Elizabeth S Yeh Patricia L Yeyati Fan Yi Long Yi Xiao-Ming Yin Calvin K Yip Yeong-Min Yoo Young Hyun Yoo Seung-Yong Yoon Ken-Ichi Yoshida Tamotsu Yoshimori Ken H Young Huixin Yu Jane J Yu Jin-Tai Yu Jun Yu Li Yu W Haung Yu Xiao-Fang Yu Zhengping Yu Junying Yuan Zhi-Min Yuan Beatrice Yjt Yue Jianbo Yue Zhenyu Yue David N Zacks Eldad Zacksenhaus Nadia Zaffaroni Tania Zaglia Zahra Zakeri Vincent Zecchini Jinsheng Zeng Min Zeng Qi Zeng Antonis S Zervos Donna D Zhang Fan Zhang Guo Zhang Guo-Chang Zhang Hao Zhang Hong Zhang Hong Zhang Hongbing Zhang Jian Zhang Jian Zhang Jiangwei Zhang Jianhua Zhang Jing-Pu Zhang Li Zhang Lin Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xiangnan Zhang Xu Dong Zhang Yan Zhang Yang Zhang Yanjin Zhang Yingmei Zhang Yunjiao Zhang Mei Zhao Wei-Li Zhao Xiaonan Zhao Yan G Zhao Ying Zhao Yongchao Zhao Yu-Xia Zhao Zhendong Zhao Zhizhuang J Zhao Dexian Zheng Xi-Long Zheng Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Guang-Zhou Zhou Guofei Zhou Huiping Zhou Shu-Feng Zhou Xu-Jie Zhou Hongxin Zhu Hua Zhu Wei-Guo Zhu Wenhua Zhu Xiao-Feng Zhu Yuhua Zhu Shi-Mei Zhuang Xiaohong Zhuang Elio Ziparo Christos E Zois Teresa Zoladek Wei-Xing Zong Antonio Zorzano Susu M Zughaier

Autophagy 2016 ;12(1):1-222

kb Emory University, School of Medicine , Department of Microbiology and Immunology , Atlanta , GA , USA.

October 2016

Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes.

Authors:

Jan Hansen Silvie Timmers Esther Moonen-Kornips Helene Duez Bart Staels Matthijs K C Hesselink Patrick Schrauwen

Sci Rep 2016 10 19;6:35047. Epub 2016 Oct 19.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

October 2016

A Mathematical Model of the Liver Circadian Clock Linking Feeding and Fasting Cycles to Clock Function.

Authors:

Aurore Woller Hélène Duez Bart Staels Marc Lefranc

Cell Rep 2016 10;17(4):1087-1097

University of Lille, CNRS, UMR 8523-PhLAM-Physique des Lasers, Atomes et Molécules, 59000 Lille, France. Electronic address:

October 2016

Erratum: The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation.

Authors:

Marie Favennec Benjamin Hennart Robert Caiazzo Audrey Leloire Loïc Yengo Marie Verbanck Abdelilah Arredouani Michel Marre Marie Pigeyre Alban Bessede Gilles J Guillemin Giulia Chinetti Bart Staels François Pattou Beverley Balkau Delphine Allorge Philippe Froguel Odile Poulain-Godefroy

Obesity (Silver Spring) 2016 08;24(8):1821

CNRS UMR 8199, Lille, France.

August 2016

Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity.

Authors:

Dirk van Moorsel Jan Hansen Bas Havekes Frank A J L Scheer Johanna A Jörgensen Joris Hoeks Vera B Schrauwen-Hinderling Helene Duez Philippe Lefebvre Nicolaas C Schaper Matthijs K C Hesselink Bart Staels Patrick Schrauwen

Mol Metab 2016 Aug 1;5(8):635-645. Epub 2016 Jul 1.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands. Electronic address:

August 2016

Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement.

N Engl J Med 2016 Jul;375(4):335-44

From the Departments of Cardiology (E.V.B., F.V., C.H., J.-B.D., N. Debry, C.D., J.-L.A., G.S., G.L., B.M., K.M., A.M., J.-J.B., F.L., J.-C.B.), Hematology and Transfusion (A.R., E.J., C.P., A.D.-P., S.H., C.C., C.Z., B.S., J.G., S.S.), and Cardiac Surgery (E.R., N.R., A.V., F.J., V.L.), Centre Hospitalier Universitaire (CHU) Lille, INSERM Unité 1011 (E.V.B., A.R., F.V., E.R., N.R., A.V., F.J., C.P., A.D.-P., F.M., B.M., D.C., C.Z., B.S., J.G., S.S.), Université Lille, INSERM Unité 1011 - European Genomic Institute for Diabetes (E.V.B., A.R., F.V., E.R., N.R., A.V., F.J., C.P., A.D.-P., F.M., B.M., D.C., C.Z., J.G., S.S.), INSERM Unité 1167 (J.D.), Institut Pasteur de Lille (E.V.B., A.R., F.V., E.R., N.R., J.D., A.V., F.J., C.P., A.D.-P., F.M., B.M., D.C., C.Z., J.G., S.S.), and Université Lille, CHU Lille, Equipe d'accueil 2694 - Santé Publique: Epidemiologie et Qualité des Soins (J.L., A.D.), Lille, Pole d'Activité Médico-chirurgicale Cardio-vasculaire, Nouvel Hôpital Civil, CHU, Université de Strasbourg, Strasbourg (M.K., T.C., O.M.), INSERM Unité 1048 and Université Toulouse III (J.L., A.D.), Institut des Maladies Métaboliques et Cardiovasculaires (M.L., N. Dumonteil), and Laboratoire d'Hematologie (M.L.), and Service de Cardiologie (N. Dumonteil), CHU de Toulouse, Toulouse, Unité Mixte de Recherche (UMR), Centre Nationale de la Recherche Scientifique 7213, Laboratoire de Biophotonique et Pharmacologie, Faculté de Pharmacie, Université de Strasbourg, Illkirch (O.M.), and INSERM UMR-S Unité 1176, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre (P.L., P.J.L.) - all in France.

July 2016

The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.

Authors:

Nathalie Hennuyer Isabelle Duplan Charlotte Paquet Jonathan Vanhoutte Eloise Woitrain Véronique Touche Sophie Colin Emmanuelle Vallez Sophie Lestavel Philippe Lefebvre Bart Staels

Atherosclerosis 2016 06 4;249:200-8. Epub 2016 Mar 4.

European Genomic Institute for Diabetes (EGID), FR 3508, F-59000 Lille, France; Univ. Lille, F-59000 Lille, France; INSERM UMR 1011, F-59000 Lille, France; Institut Pasteur de Lille, F-59000 Lille, France. Electronic address:

June 2016

Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening.

Authors:

Vlad Ratziu Stephen A Harrison Sven Francque Pierre Bedossa Philippe Lehert Lawrence Serfaty Manuel Romero-Gomez Jérôme Boursier Manal Abdelmalek Steve Caldwell Joost Drenth Quentin M Anstee Dean Hum Remy Hanf Alice Roudot Sophie Megnien Bart Staels Arun Sanyal

Gastroenterology 2016 05 11;150(5):1147-1159.e5. Epub 2016 Feb 11.

Virginia Commonwealth University, Richmond, Virginia.

May 2016

Metabolic effects of bile acid sequestration: impact on cardiovascular risk factors.

Authors:

Valeria Spinelli Oscar Chávez-Talavera Anne Tailleux Bart Staels

Curr Opin Endocrinol Diabetes Obes 2016 Apr;23(2):138-44

aUniv Lille, UMR1011, EGID bInserm, UMR1011 cCHU Lille dInstitut Pasteur de Lille, U1011, Lille, France *Valeria Spinelli and Oscar Chávez-Talavera have contributed equally to the writing of this article.

April 2016

Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1.

Authors:

Olivier Briand Véronique Touche Sophie Colin Gemma Brufau Alberto Davalos Marleen Schonewille Fabiola Bovenga Véronique Carrière Jan Freark de Boer Camille Dugardin Béatrice Riveau Véronique Clavey Anne Tailleux Antonio Moschetta Miguel A Lasunción Albert K Groen Bart Staels Sophie Lestavel

Gastroenterology 2016 Mar 18;150(3):650-8. Epub 2015 Nov 18.

University Lille, Inserm, Centre Hospitalier Universitaire (CHU) de Lille, Institut Pasteur de Lille, U1011-European Genomic Institute for Diabetes, Lille, France.

March 2016

Perilipin2/adipophilin and ApoA-1 team up to combat atherosclerosis.

Authors:

Benoit Pourcet Bart Staels

Cardiovasc Res 2016 Feb 23;109(2):193-5. Epub 2015 Dec 23.

Univ. Lille, U1011 - EGID, Lille F-59000, France Inserm, U1011, Lille F-59000, France Institut Pasteur de Lille, Lille F-59000, France

February 2016

Comment on Patel et al. ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity. Diabetes 2016;65:85-95.

Authors:

David Montaigne Augustin Coisne Xavier Marechal Bart Staels

Diabetes 2016 Feb;65(2):e1-2

Université Lille 2; INSERM U1011; European Genomic Institute for Diabetes; and Institut Pasteur de Lille, Lille, France

February 2016

Transducin-like enhancer of split-1 is expressed and functional in human macrophages.

Authors:

Federica De Paoli Corinne Copin Jonathan Vanhoutte Bruno Derudas Manjula Vinod Christophe Zawadzki Sophie Susen François Pattou Stéphan Haulon Bart Staels Jérome Eeckhoute Giulia Chinetti-Gbaguidi

FEBS Lett 2016 Jan 30;590(1):43-52. Epub 2015 Dec 30.

Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, University of Lille, France.

January 2016

Cholesteryl-ester transfer protein (CETP): A Kupffer cell marker linking hepatic inflammation with atherogenic dyslipidemia?

Authors:

Joel T Haas Bart Staels

Hepatology 2015 Dec 24;62(6):1659-61. Epub 2015 Oct 24.

European Genomic Institute for Diabetes (E.G.I.D.), FR 3508, Lille, France.

December 2015

The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiation.

Authors:

Julie Dubois-Chevalier Bart Staels Philippe Lefebvre Jérôme Eeckhoute

Nucleus 2015 ;6(1):15-8

a Inserm UMR U1011 ; Lille , France.

November 2015

Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery Disease.

Authors:

Ahmed Elkalioubie Stephan Haulon Alain Duhamel Mickael Rosa Antoine Rauch Bart Staels Sophie Susen Eric Van Belle Annabelle Dupont

Am J Cardiol 2015 Nov 14;116(9):1451-6. Epub 2015 Aug 14.

European Genomic Institute for Diabetes, Lille, France; UNIV LILLE, Lille, France; INSERM UMR 1011, Lille, France; Institut Pasteur de Lille, Lille, France; Cardiovascular and Pulmonary, and Hematology Department, Centre Hospitalier Régional Universitaire, Lille, France. Electronic address:

November 2015

Screening strategy to generate cell specific recombination: a case report with the RIP-Cre mice.

Authors:

Valeria Spinelli Céline Martin Emilie Dorchies Emmanuelle Vallez Hélène Dehondt Mohamed-Sami Trabelsi Anne Tailleux Sandrine Caron Bart Staels

Transgenic Res 2015 Oct 20;24(5):803-12. Epub 2015 Jun 20.

European Genomic Institute for Diabetes (EGID), FR 3508, 59000, Lille, France.

October 2015

The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation.

Authors:

Marie Favennec Benjamin Hennart Robert Caiazzo Audrey Leloire Loïc Yengo Marie Verbanck Abdelilah Arredouani Michel Marre Marie Pigeyre Alban Bessede Gilles J Guillemin Giulia Chinetti Bart Staels François Pattou Beverley Balkau Delphine Allorge Philippe Froguel Odile Poulain-Godefroy

Obesity (Silver Spring) 2015 Oct 8;23(10):2066-74. Epub 2015 Sep 8.

CNRS UMR 8199, Lille, France.

October 2015

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity.

Authors:

Evie P M Broeders Emmani B M Nascimento Bas Havekes Boudewijn Brans Kay H M Roumans Anne Tailleux Gert Schaart Mostafa Kouach Julie Charton Benoit Deprez Nicole D Bouvy Felix Mottaghy Bart Staels Wouter D van Marken Lichtenbelt Patrick Schrauwen

Cell Metab 2015 Sep 30;22(3):418-26. Epub 2015 Jul 30.

Department of Human Biology and Human Movement Sciences, NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht 6200 MD, the Netherlands. Electronic address:

September 2015

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.

Nat Commun 2015 Sep 23;6:8250. Epub 2015 Sep 23.

Institut Pasteur de Lille, Lille F-59000, France.

September 2015

Atherosclerosis: Recent trials, new targets and future directions.

Authors:

Ricardo Ladeiras-Lopes Stefan Agewall Ahmed Tawakol Bart Staels Evan Stein Robert J Mentz Adelino Leite-Moreira Faiez Zannad Wolfgang Koenig

Int J Cardiol 2015 Aug 8;192:72-81. Epub 2015 May 8.

Department of Internal Medicine II - Cardiology, University of Ulm Medical Center, Ulm, Germany; Deutsches Herzzentrum München, Technische Universität München, Munich Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany. Electronic address:

August 2015

Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Pparα Deficiency.

Authors:

Michal Pawlak Eric Baugé Fanny Lalloyer Philippe Lefebvre Bart Staels

Mol Endocrinol 2015 Aug 18;29(8):1134-43. Epub 2015 Jun 18.

European Genomic Institute for Diabetes, Inserm UMR1011, and University Lille, F-59000 Lille Cédex, France; and Institut Pasteur de Lille, F-59019 Lille Cédex, France.

August 2015

Bariatric surgery, lipoprotein metabolism and cardiovascular risk.

Authors:

Anne Tailleux Konstantinos Rouskas François Pattou Bart Staels

Curr Opin Lipidol 2015 Aug;26(4):317-24

aEuropean Genomic Institute for Diabetes (EGID) bINSERM UMR1011 cUniv Lille 2 dInstitut Pasteur de Lille, Lille, France eBiomedical Sciences Research Center 'Alexander Fleming', Vari, Greece fINSERM UMR1190, Lille, France.

August 2015

PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis.

Authors:

Sven Francque An Verrijken Sandrine Caron Janne Prawitt Réjane Paumelle Bruno Derudas Philippe Lefebvre Marja-Riitta Taskinen Wim Van Hul Ilse Mertens Guy Hubens Eric Van Marck Peter Michielsen Luc Van Gaal Bart Staels

J Hepatol 2015 Jul 19;63(1):164-73. Epub 2015 Feb 19.

Université Lille 2, INSERM U1011, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille, France.

July 2015

M1 and M2 macrophage proteolytic and angiogenic profile analysis in atherosclerotic patients reveals a distinctive profile in type 2 diabetes.

Authors:

Charlotte Roma-Lavisse Madjid Tagzirt Christophe Zawadzki Rodrigo Lorenzi André Vincentelli Stephan Haulon Francis Juthier Antoine Rauch Delphine Corseaux Bart Staels Brigitte Jude Eric Van Belle Sophie Susen Giulia Chinetti-Gbaguidi Annabelle Dupont

Diab Vasc Dis Res 2015 Jul 11;12(4):279-89. Epub 2015 May 11.

INSERM U1011, Laboratoire de Recherche J&K, Institut Pasteur de Lille, Faculté de Médecine - Pôle recherche, University of Lille Nord de France, EGID, Lille, France Cardiovascular and Pulmonary and Haematology Departments, University Hospital, Lille, France

July 2015

Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells.

Nat Commun 2015 Jul 2;6:7629. Epub 2015 Jul 2.

1] European Genomic Institute for Diabetes (EGID), FR 3508, Lille F-59000, France [2] Université de Lille, Lille F-59000, France [3] INSERM UMR 1011, Lille F-59000, France [4] Institut Pasteur de Lille, Lille F-59000, France.

July 2015

Structural and functional changes in HDL with low grade and chronic inflammation.

Authors:

Francis O'Neill Meliana Riwanto Marietta Charakida Sophie Colin Jasmin Manz Eve McLoughlin Tauseef Khan Nigel Klein Christopher W M Kay Kalpesh Patel Giulia Chinetti Bart Staels Francesco D'Aiuto Ulf Landmesser John Deanfield

Int J Cardiol 2015 Jun 5;188:111-6. Epub 2015 Mar 5.

National Centre for Cardiovascular Prevention and Outcomes (NCCPO), Institute of Cardiovascular Science, University College London, London, UK; National Institute for Cardiovascular Outcomes Research, University College London, London, UK. Electronic address:

June 2015

MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids.

Authors:

Xianghui Fu Bingning Dong Yan Tian Philippe Lefebvre Zhipeng Meng Xichun Wang François Pattou Weidong Han Xiaoqiong Wang Fang Lou Richard Jove Bart Staels David D Moore Wendong Huang

J Clin Invest 2015 Jun 11;125(6):2497-509. Epub 2015 May 11.

June 2015

Nuclear bile acid signaling through the farnesoid X receptor.

Authors:

Claire Mazuy Audrey Helleboid Bart Staels Philippe Lefebvre

Cell Mol Life Sci 2015 May 16;72(9):1631-50. Epub 2014 Dec 16.

European Genomic Institute for Diabetes (EGID), 59000, Lille, France.

May 2015

Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.

Authors:

Caroline Bonner Julie Kerr-Conte Valéry Gmyr Gurvan Queniat Ericka Moerman Julien Thévenet Cédric Beaucamps Nathalie Delalleau Iuliana Popescu Willy J Malaisse Abdullah Sener Benoit Deprez Amar Abderrahmani Bart Staels François Pattou

Nat Med 2015 May 20;21(5):512-7. Epub 2015 Apr 20.

1] European Genomic Institute for Diabetes, Lille, France. [2] INSERM UMR 1190, Lille, France. [3] Centre Hospitalier Régional Universitaire, Lille, France. [4] Université de Lille, Lille, France.

May 2015

Adventitial Tertiary Lymphoid Organs as Potential Source of MicroRNA Biomarkers for Abdominal Aortic Aneurysm.

Authors:

Rafaelle Spear Ludovic Boytard Renaud Blervaque Maggy Chwastyniak David Hot Jonathan Vanhoutte Bart Staels Yves Lemoine Nicolas Lamblin François-René Pruvot Stephan Haulon Philippe Amouyel Florence Pinet

Int J Mol Sci 2015 May 18;16(5):11276-93. Epub 2015 May 18.

National Institute of Health and Medical Research (INSERM) U1167, Lille Pasteur Institute, Lille North of France University, F-59000 Lille, France.

May 2015

Emerging small molecule drugs.

Authors:

Sophie Colin Giulia Chinetti-Gbaguidi Jan A Kuivenhoven Bart Staels

Handb Exp Pharmacol 2015 ;224:617-30

Université Lille 2, F-59000, Lille, France.

April 2015

Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs?

Authors:

Sarah Anissa Hannou Kristiaan Wouters Réjane Paumelle Bart Staels

Trends Endocrinol Metab 2015 Apr 3;26(4):176-84. Epub 2015 Mar 3.

University of Lille, F-59000, Lille, France; Inserm, U1011, F-59000, Lille, France; European Genomic Institute for Diabetes (EGID), FR3508, Lille, France; Institut Pasteur de Lille, F-59019, Lille, France. Electronic address:

April 2015

From cardiac mitochondrial dysfunction to clinical arrhythmias.

Authors:

David Montaigne Xavier Maréchal Dominique Lacroix Bart Staels

Int J Cardiol 2015 Apr 3;184:597-9. Epub 2015 Mar 3.

Université Lille 2, F-59000 Lille, France; Inserm, U1011, F-59000 Lille, France; EGID, F-59000 Lille, France; Institut Pasteur de Lille, F-59019 Lille, France.

April 2015

SREBF2-embedded mir33 links the nuclear bile acid receptor FXR to cholesterol and lipoprotein metabolism.

Authors:

Philippe Lefebvre Bart Staels

Arterioscler Thromb Vasc Biol 2015 Apr;35(4):748-9

From the European Genomic Institute for Diabetes (EGID), Lille, France (P.L., B.S.); INSERM UMR1011, Lille, France (P.L., B.S.); University of Lille, Lille, France (P.L., B.S.); and Institut Pasteur de Lille, Lille, France (P.L., B.S.).

April 2015

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease.

Authors:

Michal Pawlak Philippe Lefebvre Bart Staels

J Hepatol 2015 Mar 1;62(3):720-33. Epub 2014 Nov 1.

European Genomic Institute for Diabetes (EGID), FR 3508, F-59000 Lille, France; Université Lille 2, F-59000 Lille, France; Inserm UMR 1011, F-59000 Lille, France; Institut Pasteur de Lille, F-59000 Lille, France. Electronic address:

March 2015

Von Willebrand factor as a biological sensor of blood flow to monitor percutaneous aortic valve interventions.

Circ Res 2015 Mar 10;116(7):1193-201. Epub 2015 Feb 10.

From the Department of Cardiology, Lille University Hospital, Lille, France (E.V.B., A.V., F.J., C.H., C.B., N.R., C.D., G.S., D.D.); INSERM UMR 1011, Univ Lille 2, Institut Pasteur de Lille, EGID, Lille, France (E.V.B., A.R., A.V., E.J., F.J., C.B., N.R., C.C., A.E., D.C., A.D., C.Z., G.C., B.S., J.G., B.J., S.S.); Department of Hematology, Transfusion Lille University Hospital, Lille, France (A.R., E.J., C.C., A.E., C.Z., F.M., J.G., B.J., S.S.); INSERM U1176 and UMR_S1176, Univ Paris-Sud, Le Kremlin Bicêtre, France (P.L., P.J.L.); and INSERM UMR 1140, Paris, France (A.G.).

March 2015

Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.

Circulation 2015 Mar 11;131(10):871-81. Epub 2015 Feb 11.

From Centre for Molecular Cardiology, University of Zurich and University Heart Center, Cardiology, University Hospital Zurich, Switzerland (E.O., P.D., S.S., J.M., U.L., C.M.M., T.F.L.); Institute of Veterinary Physiology, University of Zurich, Switzerland (P.D., C.C., C.D., H.B., K.S., T.A.L.); Department of Surgery (M.B., D.V.) and Institute of Clinical Chemistry (L.R., R.H.), University Hospital Zurich, Switzerland; Université Lille 2, INSERM UMR1011, EGID, Institut Pasteur de Lille, France (S.C., A.T., B.S.); Department of Health Sciences and Technology, ETH Zurich, Switzerland (C.W.); Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Italy (F.T.); State Key Laboratory for Pharmaceutical Biotechnology and Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, University of Hong Kong, SAR (P.M.V.); and Department of Endocrine Surgery, Lille University Hospital, France (F.P.).

March 2015

A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation.

Authors:

Julie Dubois-Chevalier Frédérik Oger Hélène Dehondt François F Firmin Céline Gheeraert Bart Staels Philippe Lefebvre Jérôme Eeckhoute

Nucleic Acids Res 2014 2;42(17):10943-59. Epub 2014 Sep 2.

Inserm UMR U1011, F-59000 Lille, France Université Lille 2, F-59000 Lille, France Institut Pasteur de Lille, F-59019 Lille, France European Genomic Institute for Diabetes (EGID), FR 3508, F-59000 Lille, France

February 2015

Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.

Proc Natl Acad Sci U S A 2015 Feb 9;112(8):2473-8. Epub 2015 Feb 9.

INSERM, U1068, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, CNRS, UMR7258, and Université Aix-Marseille, F-13009 Marseille, France;

February 2015

Macrophage subsets in atherosclerosis.

Authors:

Giulia Chinetti-Gbaguidi Sophie Colin Bart Staels

Nat Rev Cardiol 2015 Jan 4;12(1):10-7. Epub 2014 Nov 4.

INSERM U1011, Institut Pasteur de Lille, 1, Rue du Professeur Calmette, BP 245, Lille 59019, France.

January 2015

Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.

Eur J Med Chem 2015 Jan 4;90:547-67. Epub 2014 Dec 4.

INSERM U761 Biostructures and Drug Discovery, Lille, France; Lille F-59000, France; Institut Pasteur de Lille, IFR 142, Lille F-59000, France; PRIM, Lille F-59000, France; CDithem Platform/IGM, Paris, France. Electronic address:

January 2015

O-GlcNAcylation Links ChREBP and FXR to Glucose-Sensing.

Authors:

Fadila Benhamed Gaelle Filhoulaud Sandrine Caron Philippe Lefebvre Bart Staels Catherine Postic

Front Endocrinol (Lausanne) 2014 13;5:230. Epub 2015 Jan 13.

U1016, Institut Cochin, INSERM , Paris , France ; UMR 8104, CNRS , Paris , France ; Sorbonne Paris Cité, Université Paris Descartes , Paris , France.

January 2015

The dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 exerts anti-diabetic effects in db/db mice without peroxisome proliferator-activated receptor gamma-associated adverse cardiac effects.

Authors:

Rémy Hanf Lesley J Millatt Bertrand Cariou Benoit Noel Géraldine Rigou Philippe Delataille Valérie Daix Dean W Hum Bart Staels

Diab Vasc Dis Res 2014 Nov 11;11(6):440-7. Epub 2014 Sep 11.

Institut Pasteur de Lille, Lille, France Inserm, UMR 1011, Lille, France Université de Lille 2, Lille, France EGID, Lille, France

November 2014

Macrophage phenotypes in atherosclerosis.

Authors:

Sophie Colin Giulia Chinetti-Gbaguidi Bart Staels

Immunol Rev 2014 Nov;262(1):153-66

Université Lille 2, Lille, France; Inserm, U1011, Lille, France; Institut Pasteur de Lille, Lille, France; European Genomic Institute for Diabetes (EGID), FR 3508, Lille, France.

November 2014

Neuroprostanes, produced by free-radical mediated peroxidation of DHA, inhibit the inflammatory response of human macrophages.

Authors:

Cécile Gladine Joumard-Cubizolles Laurie Chinetti Giulia Bayle Dominique Copin Corinne Hennuyer Nathalie Staels Bart Zanoni Giuseppe Porta Alessio Galano Jean-Marie Oger Camille Durand Thierry

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S15. Epub 2014 Dec 10.

CNRS (IBMM), IBMM, France.

October 2014