Publications by authors named "Barry R Stripp"

67Publications

Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.

Cell Stem Cell 2020 Oct 19. Epub 2020 Oct 19.

Center for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University and Boston Medical Center, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2020.09.017DOI Listing
October 2020

Isolation and Enrichment of Human Lung Epithelial Progenitor Cells for Organoid Culture.

J Vis Exp 2020 07 21(161). Epub 2020 Jul 21.

Lung and Regenerative Medicine Institutes, Department of Medicine, Cedars-Sinai Medical Center;

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http://dx.doi.org/10.3791/61541DOI Listing
July 2020

Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis.

Hum Gene Ther 2020 Sep 8;31(17-18):956-972. Epub 2020 Sep 8.

Center for Stem Cell and Regenerative Medicine, Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1089/hum.2020.160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495916PMC
September 2020

Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells.

iScience 2020 May 21;23(5):101083. Epub 2020 Apr 21.

Hastings Center for Pulmonary Research and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Norris Comprehensive Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.101083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205764PMC
May 2020

Alveolar Epithelial Type II Cells as Drivers of Lung Fibrosis in Idiopathic Pulmonary Fibrosis.

Int J Mol Sci 2020 Mar 25;21(7). Epub 2020 Mar 25.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.3390/ijms21072269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177323PMC
March 2020

Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.

Stem Cell Reports 2018 05 12;10(5):1579-1595. Epub 2018 Apr 12.

Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995784PMC
May 2018

The Impact of Allograft CXCL9 during Respiratory Infection on the Risk of Chronic Lung Allograft Dysfunction.

OBM Transplant 2018 30;2(4). Epub 2018 Nov 30.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1690, USA.

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http://dx.doi.org/10.21926/obm.transplant.1804029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693350PMC
November 2018

Sin3a regulates epithelial progenitor cell fate during lung development.

Development 2017 07 15;144(14):2618-2628. Epub 2017 Jun 15.

Lung and Regenerative Medicine Institutes, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA

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http://dx.doi.org/10.1242/dev.149708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536929PMC
July 2017

Roles for Myoepithelial Cells in the Formation and Maintenance of Submucosal Glands.

Am J Respir Cell Mol Biol 2017 06;56(6):685-686

1 Department of Medicine Cedars-Sinai Medical Center Los Angeles, California.

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http://dx.doi.org/10.1165/rcmb.2017-0044EDDOI Listing
June 2017

Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis.

JCI Insight 2016 12 8;1(20):e90558. Epub 2016 Dec 8.

Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1172/jci.insight.90558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135277PMC
December 2016

miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways.

JCI Insight 2016 12 8;1(20):e90301. Epub 2016 Dec 8.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

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http://dx.doi.org/10.1172/jci.insight.90301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135276PMC
December 2016

p53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway.

Cell Rep 2016 11;17(9):2173-2182

Lung and Regenerative Medicine Institutes, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27708, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.007DOI Listing
November 2016

Rare SOX2 Airway Progenitor Cells Generate KRT5 Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection.

Stem Cell Reports 2016 11 20;7(5):817-825. Epub 2016 Oct 20.

Lung and Regenerative Medicine Institutes, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106521PMC
November 2016

Distal airway epithelial progenitor cells are radiosensitive to High-LET radiation.

Sci Rep 2016 Sep 23;6:33455. Epub 2016 Sep 23.

Department of Cell Biology, Duke University Medical Center, Durham, NC, 27708, USA.

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http://dx.doi.org/10.1038/srep33455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034250PMC
September 2016

A new notch for lung stem cells.

Cell Stem Cell 2015 Feb;16(2):107-9

Departments of Medicine and Biomedical Sciences, Lung and Regenerative Medicine Institutes, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.01.012DOI Listing
February 2015

Low- and high-LET radiation drives clonal expansion of lung progenitor cells in vivo.

Radiat Res 2015 Jan 7;183(1):124-32. Epub 2015 Jan 7.

a  Departments of Medicine and Cell Biology, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1667/RR13878.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409869PMC
January 2015

Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung.

J Mol Cell Biol 2015 Feb 5;7(1):35-47. Epub 2014 Dec 5.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229-3039, USA

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http://dx.doi.org/10.1093/jmcb/mju046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400400PMC
February 2015

Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis.

Cell 2014 Jan;156(3):440-55

Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674140000
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http://dx.doi.org/10.1016/j.cell.2013.12.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951122PMC
January 2014

Type 2 alveolar cells are stem cells in adult lung.

J Clin Invest 2013 Jul 10;123(7):3025-36. Epub 2013 Jun 10.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1172/JCI68782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696553PMC
July 2013

Building and maintaining the epithelium of the lung.

J Clin Invest 2012 Aug 1;122(8):2724-30. Epub 2012 Aug 1.

Pulmonary, Allergy and Critical Care, Department of Medicine, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1172/JCI60519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408736PMC
August 2012

Amphiregulin-dependent mucous cell metaplasia in a model of nonallergic lung injury.

Am J Respir Cell Mol Biol 2012 Sep 5;47(3):349-57. Epub 2012 Apr 5.

Division of Pulmonary, Allergy and Critical Care, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1165/rcmb.2011-0257OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488692PMC
September 2012

β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.

J Cell Sci 2012 Feb 15;125(Pt 4):932-42. Epub 2012 Mar 15.

Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, 106 Research Drive, 2075 MSRBII, DUMC Box 103000, Durham, NC, 27710, USA.

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http://jcs.biologists.org/lookup/doi/10.1242/jcs.092734
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http://dx.doi.org/10.1242/jcs.092734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311930PMC
February 2012

Antimicrobial activity of PLUNC protects against Pseudomonas aeruginosa infection.

J Immunol 2011 Jul 1;187(1):382-90. Epub 2011 Jun 1.

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.4049/jimmunol.1001769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119743PMC
July 2011

c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice.

Am J Respir Crit Care Med 2011 06 11;183(12):1644-52. Epub 2011 Mar 11.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1164/rccm.201007-1157OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136992PMC
June 2011

Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.

Am J Respir Cell Mol Biol 2011 Jun 23;44(6):794-803. Epub 2010 Jul 23.

Division of Pulmonary, Allergy and Critical Care, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1165/rcmb.2010-0098OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135841PMC
June 2011

Bronchiolar progenitor cells.

Proc Am Thorac Soc 2009 Dec;6(7):602-6

Division of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, 106 Research Drive, Durham, NC 27710, USA.

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http://dx.doi.org/10.1513/pats.200907-078RMDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266052PMC
December 2009

Stem cells are dispensable for lung homeostasis but restore airways after injury.

Proc Natl Acad Sci U S A 2009 Jun 28;106(23):9286-91. Epub 2009 May 28.

Cancer Research UK, Cambridge Research Institute, Cambridge, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0900668106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687999PMC
June 2009

Clara cells attenuate the inflammatory response through regulation of macrophage behavior.

Am J Respir Cell Mol Biol 2010 Feb 7;42(2):161-71. Epub 2009 May 7.

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2008-0353OC
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http://dx.doi.org/10.1165/rcmb.2008-0353OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822978PMC
February 2010

beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium.

Am J Respir Cell Mol Biol 2009 Nov 12;41(5):535-43. Epub 2009 Feb 12.

Center for Lung Regeneration, Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1165/rcmb.2008-0407OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778160PMC
November 2009

Reparative capacity of airway epithelium impacts deposition and remodeling of extracellular matrix.

Am J Respir Cell Mol Biol 2009 Jun 31;40(6):633-42. Epub 2008 Oct 31.

Department of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2008-0334OC
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http://dx.doi.org/10.1165/rcmb.2008-0334OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689915PMC
June 2009

Molecular staging of epithelial maturation using secretory cell-specific genes as markers.

Am J Respir Cell Mol Biol 2009 Mar 28;40(3):340-8. Epub 2008 Aug 28.

Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, 2075 MSRBII, 106 Research Drive, DUMC Box 103000, Durham, NC 27710, USA.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2007-0380OC
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http://dx.doi.org/10.1165/rcmb.2007-0380OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645532PMC
March 2009

Hierarchical organization of lung progenitor cells: is there an adult lung tissue stem cell?

Authors:
Barry R Stripp

Proc Am Thorac Soc 2008 Aug;5(6):695-8

Division of Pulmonary, Allergy and Critical Care, Duke University Medical Center, 2075 MSRBII, 106 Research Drive, DUMC Box 103000, Durham, NC 27710, USA.

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http://dx.doi.org/10.1513/pats.200801-011AWDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645261PMC
August 2008

Maintenance and repair of the bronchiolar epithelium.

Proc Am Thorac Soc 2008 Apr;5(3):328-33

Division of Pulmonary, Allergy, and Critical Care, Duke University Medical Center, 2075 MSRBII, 106 Research Drive, DUMC Box 103000, Durham, NC 27710, USA.

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http://pats.atsjournals.org/cgi/doi/10.1513/pats.200711-167D
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http://dx.doi.org/10.1513/pats.200711-167DRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645243PMC
April 2008

Conditional stabilization of beta-catenin expands the pool of lung stem cells.

Stem Cells 2008 May 20;26(5):1337-46. Epub 2008 Mar 20.

Center for Lung Regeneration, Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1634/stemcells.2008-0053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773682PMC
May 2008

CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway.

Am J Physiol Lung Cell Mol Physiol 2007 Jul 23;293(1):L114-23. Epub 2007 Mar 23.

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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http://www.physiology.org/doi/10.1152/ajplung.00014.2007
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http://dx.doi.org/10.1152/ajplung.00014.2007DOI Listing
July 2007

Molecular and functional properties of lung SP cells.

Am J Physiol Lung Cell Mol Physiol 2007 Apr 1;292(4):L972-83. Epub 2006 Dec 1.

Center for Lung Regeneration, Department of Environmental and Occupational Health, University of Pittsburgh, USA.

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http://dx.doi.org/10.1152/ajplung.00090.2006DOI Listing
April 2007

Clara cell secretory protein and phospholipase A2 activity modulate acute ventilator-induced lung injury in mice.

J Appl Physiol (1985) 2005 Apr 17;98(4):1264-71. Epub 2004 Dec 17.

Dept. of Physiology, MSB 3074, Univ. of South Alabama, Mobile, AL 36688, USA.

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http://dx.doi.org/10.1152/japplphysiol.01150.2004DOI Listing
April 2005

Airway injury in lung disease pathophysiology: selective depletion of airway stem and progenitor cell pools potentiates lung inflammation and alveolar dysfunction.

Am J Physiol Lung Cell Mol Physiol 2004 Dec 6;287(6):L1256-65. Epub 2004 Aug 6.

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1152/ajplung.00203.2004DOI Listing
December 2004

Mucin is produced by clara cells in the proximal airways of antigen-challenged mice.

Am J Respir Cell Mol Biol 2004 Oct 10;31(4):382-94. Epub 2004 Jun 10.

Pulmonary Medicine, M.D. Anderson Cancer Center, 2121 West Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1165/rcmb.2004-0060OCDOI Listing
October 2004

Time and pressure dependence of transvascular Clara cell protein, albumin, and IgG transport during ventilator-induced lung injury in mice.

Am J Physiol Lung Cell Mol Physiol 2004 Mar;286(3):L604-12

Department of Physiology, University of South Alabama, Mobile, AL 36688, USA.

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http://dx.doi.org/10.1152/ajplung.00283.2003DOI Listing
March 2004

Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium.

Am J Pathol 2004 Feb;164(2):577-88

Department of Environmental Medicine, University of Rochester, Rochester, New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602270PMC
http://dx.doi.org/10.1016/S0002-9440(10)63147-1DOI Listing
February 2004

Molecular phenotype of airway side population cells.

Am J Physiol Lung Cell Mol Physiol 2004 Apr 8;286(4):L624-30. Epub 2003 Aug 8.

Univ. of Pittsburgh, FORBL Rm. 314, 3343 Forbes Ave., Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1152/ajplung.00149.2003DOI Listing
April 2004

In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations.

Am J Physiol Lung Cell Mol Physiol 2004 Apr 18;286(4):L643-9. Epub 2003 Jul 18.

Dept. of Environmental and Occupational Health, Univ. of Pittsburgh, FORBL Rm. 314, 3343 Forbes Ave., Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1152/ajplung.00155.2003DOI Listing
April 2004

Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.

Am J Respir Crit Care Med 2002 Dec 1;166(11):1498-509. Epub 2002 Aug 1.

Departments of Environmental and Occupational Health, and Pediatrics, University of Pittsburgh, Pennsylvania 15260, USA.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200204-285OC
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http://dx.doi.org/10.1164/rccm.200204-285OCDOI Listing
December 2002

Clara cell secretory protein deficiency alters clara cell secretory apparatus and the protein composition of airway lining fluid.

Am J Respir Cell Mol Biol 2002 Aug;27(2):170-8

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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http://dx.doi.org/10.1165/ajrcmb.27.2.200200270cDOI Listing
August 2002

Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction.

Am J Pathol 2002 Jul;161(1):173-82

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850682PMC
http://dx.doi.org/10.1016/S0002-9440(10)64169-7DOI Listing
July 2002