Barnett S Kramer

Barnett S Kramer

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Barnett S Kramer

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Cancer overdiagnosis: a biological challenge and clinical dilemma.

Nat Rev Cancer 2019 06;19(6):349-358

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41568-019-0142-8DOI Listing
June 2019

Conceptualizing De-Implementation in Cancer Care Delivery.

J Clin Oncol 2019 Jan 8;37(2):93-96. Epub 2018 Nov 8.

1 National Cancer Institute, Rockville, MD.

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http://ascopubs.org/doi/10.1200/JCO.18.00589
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http://dx.doi.org/10.1200/JCO.18.00589DOI Listing
January 2019

Focusing on overdiagnosis as a driver of too much medicine.

BMJ 2018 Aug 17;362:k3494. Epub 2018 Aug 17.

Center for Medicine and the Media, Dartmouth Institute for Health Policy and Clinical Practice, USA.

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http://dx.doi.org/10.1136/bmj.k3494DOI Listing
August 2018

Validation: a critical step in bringing biomarkers to clinical fruition.

Ann Epidemiol 2018 02 9;28(2):135-138. Epub 2017 Nov 9.

National Cancer Institute, Rockville, MD.

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http://dx.doi.org/10.1016/j.annepidem.2017.10.013DOI Listing
February 2018

The bimanual ovarian palpation examination in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: Performance and complications.

J Med Screen 2017 12 30;24(4):220-222. Epub 2016 Nov 30.

Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/0969141316680381DOI Listing
December 2017

Editorial: Challenges in Quantifying Overdiagnosis.

J Natl Cancer Inst 2017 10;109(10)

Affiliation of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1093/jnci/djx064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279281PMC
October 2017

Incidental renal tumours on low-dose CT lung cancer screening exams.

J Med Screen 2017 06 9;24(2):104-109. Epub 2016 Oct 9.

1 Division of Cancer Prevention, National Cancer Institute, Bethesda, USA.

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http://dx.doi.org/10.1177/0969141316657115DOI Listing
June 2017

Prostate Cancer Screening - A Perspective on the Current State of the Evidence.

N Engl J Med 2017 03;376(13):1285-1289

From the Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1056/NEJMsb1616281DOI Listing
March 2017

Breast-Cancer Tumor Size and Screening Effectiveness.

N Engl J Med 2017 01;376(1):94-5

National Cancer Institute, Bethesda, MD

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http://dx.doi.org/10.1056/NEJMc1614282DOI Listing
January 2017

Cancer Prevention: Lessons Learned and Future Directions.

Trends Cancer 2016 12;2(12):713-722

National Cancer Institute, Division of Cancer Prevention, 9609 Medical Center Drive, MSC 9787, Bethesda, MD 20892-9787, USA.

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http://dx.doi.org/10.1016/j.trecan.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271581PMC
December 2016

Extended mortality results for ovarian cancer screening in the PLCO trial with median 15years follow-up.

Gynecol Oncol 2016 Nov 9;143(2):270-275. Epub 2016 Sep 9.

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077651PMC
http://dx.doi.org/10.1016/j.ygyno.2016.08.334DOI Listing
November 2016

Breast-Cancer Tumor Size, Overdiagnosis, and Mammography Screening Effectiveness.

N Engl J Med 2016 10;375(15):1438-1447

From the Dartmouth Institute for Health Policy and Clinical Practice, Lebanon (H.G.W., A.J.O.), and the Departments of Medicine (H.G.W.) and Biomedical Data Science (A.J.O.), Geisel School of Medicine, Hanover - both in New Hampshire; and the Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (P.C.P., B.S.K.).

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http://www.nejm.org/doi/10.1056/NEJMoa1600249
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http://dx.doi.org/10.1056/NEJMoa1600249DOI Listing
October 2016

Research Needs for Understanding the Biology of Overdiagnosis in Cancer Screening.

J Cell Physiol 2016 09 29;231(9):1870-5. Epub 2016 Apr 29.

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://doi.wiley.com/10.1002/jcp.25227
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http://dx.doi.org/10.1002/jcp.25227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811189PMC
September 2016

Population-based screening for cancer: hope and hype.

Nat Rev Clin Oncol 2016 09 13;13(9):550-65. Epub 2016 Apr 13.

Departments of Surgery and Radiology, University of California, San Francisco, 1600 Divisadero Street, Box 1710, San Francisco, California 94115, USA.

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http://dx.doi.org/10.1038/nrclinonc.2016.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585415PMC
September 2016

The PLCO Cancer Screening Trial: Background, Goals, Organization, Operations, Results.

Rev Recent Clin Trials 2015 ;10(3):173-80

Office of Disease Prevention, Office of the Director, National Institutes of Health, 6100 Executive Blvd, Ste. 2B03, Rockville, MD 20892, USA.

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July 2016

Comprehensive Quality Management (CQM) in the PLCO Trial.

Rev Recent Clin Trials 2015 ;10(3):223-32

Office of Disease Prevention, Office of the Director, National Institutes of Health, 6100 Executive Blvd. Ste. 2B03. Rockville, MD 20892, USA.

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July 2016

Screening for Prostate Cancer with Prostate-Specific Antigen: What's the Evidence?

Am Soc Clin Oncol Educ Book 2012 :96-100

From the Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.14694/EdBook_AM.2012.32.96DOI Listing
April 2016

Latent class instrumental variables: a clinical and biostatistical perspective.

Stat Med 2016 Jan 4;35(1):147-60. Epub 2015 Aug 4.

Department of Anesthesiology, Johns Hopkins Medical Institutions, Baltimore, MD, U.S.A.

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http://dx.doi.org/10.1002/sim.6612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715605PMC
January 2016

Reply to J. Cabezas et al.

J Clin Oncol 2016 Jan 7;34(3):290-1. Epub 2015 Dec 7.

University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.2015.64.3064DOI Listing
January 2016

Study designs for determining and comparing sensitivities of disease screening tests.

J Med Screen 2015 Dec 22;22(4):213-20. Epub 2015 Sep 22.

Dalla Lana School of Public Health, University of Toronto.

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http://dx.doi.org/10.1177/0969141315600003DOI Listing
December 2015

Predictive Value Tools as an Aid in Chemopreventive Agent Development.

J Natl Cancer Inst 2015 Dec 28;107(12):djv259. Epub 2015 Sep 28.

Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland (BKD, VES, RMF, RL, LGF, BSK); CCS Associates, Inc., McLean, VA (CFT); Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC (DR); Information Management Services, Rockville, MD (CC).

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http://dx.doi.org/10.1093/jnci/djv259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862414PMC
December 2015

Lung Cancer Risk and Demographic Characteristics of Current 20-29 Pack-year Smokers: Implications for Screening.

J Natl Cancer Inst 2015 Nov 19;107(11). Epub 2015 Oct 19.

Division of Cancer Prevention, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1093/jnci/djv226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849359PMC
November 2015

Lung cancer risk by years since quitting in 30+ pack year smokers.

J Med Screen 2015 Sep 29;22(3):151-7. Epub 2015 Apr 29.

Division of Cancer Prevention, National Cancer Institute.

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http://dx.doi.org/10.1177/0969141315579119DOI Listing
September 2015

Evaluating surrogate endpoints, prognostic markers, and predictive markers: Some simple themes.

Clin Trials 2015 Aug 10;12(4):299-308. Epub 2014 Nov 10.

Division of Cancer Prevention, National Cancer Institute, Bethesda MD, USA.

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http://dx.doi.org/10.1177/1740774514557725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451440PMC
August 2015

Evaluating Prognostic Markers Using Relative Utility Curves and Test Tradeoffs.

J Clin Oncol 2015 Aug 29;33(23):2578-80. Epub 2015 Jun 29.

All authors: National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1200/JCO.2014.58.0092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525050PMC
August 2015

Cancer Care Delivery Research: Building the Evidence Base to Support Practice Change in Community Oncology.

J Clin Oncol 2015 Aug 20;33(24):2705-11. Epub 2015 Jul 20.

Erin E. Kent, Sandra A. Mitchell, Kathleen M. Castro, Worta J. McCaskill-Stevens, Barnett S. Kramer, and Steven B. Clauser, National Cancer Institute, National Institutes of Health (NIH); Rachel M. Ballard, NIH Office of Disease Prevention, Bethesda, MD; Darren A. DeWalt and Arnold D. Kaluzny, University of North Carolina at Chapel Hill, Chapel Hill, NC; and Judith A. Hautala and Oren Grad, Institute for Defense Analyses Science and Technology Policy Institute, Alexandria, VA.

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http://dx.doi.org/10.1200/JCO.2014.60.6210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559611PMC
August 2015

Projecting the benefits and harms of mammography using statistical models: proof or proofiness?

J Natl Cancer Inst 2015 Jul 29;107(7). Epub 2015 Apr 29.

University of Washington School of Medicine, Harborview Medical Center, 325 Ninth Avenue, Box 359780, Seattle, WA 98104-2499.

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http://dx.doi.org/10.1093/jnci/djv145DOI Listing
July 2015

Hepatitis B Virus Screening for Patients With Cancer Before Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update.

J Clin Oncol 2015 Jul 11;33(19):2212-20. Epub 2015 May 11.

Jessica P. Hwang, University of Texas MD Anderson Cancer Center; Anita L. Sabichi, Baylor College of Medicine, Houston, TX; Mark R. Somerfield, American Society of Clinical Oncology, Alexandria, VA; Devena E. Alston-Johnson, Upstate Oncology Associates, Greenville, SC; Donna R. Cryer, Global Liver Institute, Washington, DC; Jordan J. Feld, Toronto Western Hospital Liver Centre, Toronto, Ontario, Canada; Barnett S. Kramer, National Cancer Institute, Bethesda, MD; Sandra L. Wong, University of Michigan, Ann Arbor, MI; and Andrew S. Artz, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.2015.61.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477791PMC
July 2015

Conceptualizing overdiagnosis in cancer screening.

J Natl Cancer Inst 2015 Apr 6;107(4). Epub 2015 Feb 6.

Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD (PCP, BSK); Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada (ABM); no institutional affiliation, Norwich, England, UK (EJD).

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http://dx.doi.org/10.1093/jnci/djv014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334818PMC
April 2015

Leveraging biospecimen resources for discovery or validation of markers for early cancer detection.

J Natl Cancer Inst 2015 Apr 16;107(4). Epub 2015 Feb 16.

: Division of Cancer Control and Population Sciences (SDS, DMC, LEM, VPDR, MJK), Division of Cancer Prevention (SuS, BSK), and Division of Cancer Treatment and Diagnosis (LMM), National Cancer Institute, Bethesda, MD; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (GLA, NU); Department of Medicine, University of North Carolina, Chapel Hill, NC (JAB, DFR); Department of Radiation Oncology, Johns Hopkins Medicine, Baltimore, MD (CDB); Center for Prostate Disease Research, Department of Defense, Rockville, MD (JC); Mount Sinai Hospital, Toronto, Ontario, Canada (EPD); Center for Health Research, Kaiser Permanente, Northwest, Portland, OR (KABG); Division of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA (SEH); Division of Research, Kaiser Permanente, Oakland, CA (LHK); Group Health Research Institute, Seattle, WA (EBL); American Society of Clinical Oncology, Alexandria, VA (RLS); Genomic Health, Inc., Redwood City, CA (StS); Biostatistics Center, Massachusetts General Hospital, Boston, MA (SJS); Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA (MJK).

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http://dx.doi.org/10.1093/jnci/djv012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342676PMC
April 2015

Colorectal cancer prevention and fishful thinking.

J Natl Cancer Inst 2015 Apr 25;107(4). Epub 2015 Mar 25.

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http://dx.doi.org/10.1093/jnci/djv052DOI Listing
April 2015

JNCI and cancer prevention.

J Natl Cancer Inst 2015 Mar 24;107(3). Epub 2015 Feb 24.

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD (BKD, SG, BSK).

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http://dx.doi.org/10.1093/jnci/djv021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351357PMC
March 2015

Lead time and overdiagnosis.

J Natl Cancer Inst 2014 Dec 31;106(12). Epub 2014 Oct 31.

Division of Cancer Prevention, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1093/jnci/dju346DOI Listing
December 2014

Multilevel modeling and value of information in clinical trial decision support.

BMC Syst Biol 2014 Dec 24;8. Epub 2014 Dec 24.

Computer Science and Artificial Intelligence Laboratory and Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

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http://dx.doi.org/10.1186/s12918-014-0140-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304628PMC
December 2014

Estimating overdiagnosis in lung cancer screening--reply.

JAMA Intern Med 2014 Jul;174(7):1198-9

National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamainternmed.2014.1525DOI Listing
July 2014

Future directions for postdoctoral training in cancer prevention: insights from a panel of experts.

Cancer Epidemiol Biomarkers Prev 2014 Apr 6;23(4):679-83. Epub 2014 Mar 6.

Authors' Affiliations: National Cancer Institute, Bethesda; Advancing Synergy, LLC, Baltimore, Maryland; University of Texas MD Anderson Cancer Center, Houston, Texas; Schroeder Institute for Tobacco Research and Policy Studies, Legacy, Washington, District of Columbia; Centers for Disease Control and Prevention, Atlanta, Georgia; University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina; University of Kansas Medical Center, Kansas City, Kansas; Washington University School of Medicine, St. Louis, Missouri; The Ohio State University Comprehensive Cancer Center, Columbus, Ohio; and City of Hope, Duarte, California.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1
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http://dx.doi.org/10.1158/1055-9965.EPI-13-1209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976830PMC
April 2014

Breast cancer screening: toward informed decisions.

JAMA 2014 Apr;311(13):1298-9

Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jama.2014.2494DOI Listing
April 2014

The randomized registry trial.

N Engl J Med 2014 Feb;370(7):681-2

National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.1056/NEJMc1315677DOI Listing
February 2014

The National Lung Screening Trial: results stratified by demographics, smoking history, and lung cancer histology.

Cancer 2013 Nov 26;119(22):3976-83. Epub 2013 Aug 26.

Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1002/cncr.28326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936005PMC
November 2013

The prostate, lung, colorectal, and ovarian cancer screening trial and its associated research resource.

J Natl Cancer Inst 2013 Nov 10;105(22):1684-93. Epub 2013 Oct 10.

Affiliations of authors: Early Detection Research Group, Division of Cancer Prevention (CSZ, PFP, BSK, PCP, CDB) and Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute (MPP), and Office of Disease Prevention, National Institutes of Health, Bethesda, MD (JKG).

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http://dx.doi.org/10.1093/jnci/djt281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888207PMC
November 2013

The word "cancer": how language can corrupt thought.

BMJ 2013 Sep 10;347:f5328. Epub 2013 Sep 10.

Chemoprevention Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1136/bmj.f5328DOI Listing
September 2013

Surrogate endpoint analysis: an exercise in extrapolation.

J Natl Cancer Inst 2013 Mar 21;105(5):316-20. Epub 2012 Dec 21.

National Cancer Institute, EPN 3131, 6130 Executive Blvd, MSC 7354, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1093/jnci/djs527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611854PMC
March 2013

The risky reliance on small surrogate endpoint studies when planning a large prevention trial.

J R Stat Soc Ser A Stat Soc 2013 Feb 28;176(2):603-608. Epub 2012 Jun 28.

National Cancer Institute, Bethesda, USA.

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http://dx.doi.org/10.1111/j.1467-985X.2012.01052.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616635PMC
February 2013

Cancer screening campaigns--getting past uninformative persuasion.

N Engl J Med 2012 11;367(18):1677-9

VA Outcomes Group, White River Junction, VT, USA.

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http://dx.doi.org/10.1056/NEJMp1209407DOI Listing
November 2012

Evaluating a new marker for risk prediction: decision analysis to the rescue.

Discov Med 2012 Sep;14(76):181-8

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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September 2012

A population approach to precision medicine.

Am J Prev Med 2012 Jun;42(6):639-45

Office of Public Health Genomics, CDC, Atlanta, GA 30333, USA.

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http://dx.doi.org/10.1016/j.amepre.2012.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629731PMC
June 2012

Biomarkers, subgroup evaluation, and clinical trial design.

Discov Med 2012 Mar;13(70):187-92

Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland 20892, USA.

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March 2012

Systems biology and cancer: promises and perils.

Prog Biophys Mol Biol 2011 Aug 23;106(2):410-3. Epub 2011 Mar 23.

Division of Cancer Prevention, National Cancer Institute, EPN 3131, 6130 Executive Blvd MSC 7354, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1016/j.pbiomolbio.2011.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156977PMC
August 2011

National Children's Study: update in 2010.

Mt Sinai J Med 2011 Jan-Feb;78(1):119-25

Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD, USA.

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http://dx.doi.org/10.1002/msj.20227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247064PMC
May 2011

Screening for prostate cancer with PSA testing: current status and future directions.

Oncology (Williston Park) 2011 May;25(6):452-60, 463

Agency for Healthcare Research and Quality, Rockville, Maryland 20850, USA.

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May 2011

5-α-Reductase inhibitors for prostate cancer chemoprevention: an updated Cochrane systematic review.

BJU Int 2010 Nov;106(10):1444-51

Minneapolis VA Center for Chronic Disease Outcomes Research, Minneapolis, MN 55417, USA.

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http://dx.doi.org/10.1111/j.1464-410X.2010.09714.xDOI Listing
November 2010

Assessing contamination and compliance in the prostate component of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.

Clin Trials 2010 Aug 22;7(4):303-11. Epub 2010 Jun 22.

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/1740774510374091DOI Listing
August 2010

Transparency and reproducibility in data analysis: the Prostate Cancer Prevention Trial.

Biostatistics 2010 Jul 19;11(3):413-8. Epub 2010 Feb 19.

Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, 6130 Executive Boulevard, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1093/biostatistics/kxq004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883301PMC
July 2010

Principles of cancer screening: lessons from history and study design issues.

Semin Oncol 2010 Jun;37(3):202-15

Office of Medical Applications of Research, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2010.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921618PMC
June 2010

Cumulative incidence of false-positive test results in lung cancer screening: a randomized trial.

Ann Intern Med 2010 Apr;152(8):505-12, W176-80

National Institutes of Health, National Cancer Institute, Bethesda, and Information Management Services, Rockville, Maryland 20892, USA.

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http://dx.doi.org/10.7326/0003-4819-152-8-201004200-00007DOI Listing
April 2010

A common standard for conflict of interest disclosure in addiction journals.

Addiction 2009 Nov;104(11):1779-84

Center for Science in the Public Interest, Washington, DC, USA.

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http://dx.doi.org/10.1111/j.1360-0443.2009.02594.xDOI Listing
November 2009

Using relative utility curves to evaluate risk prediction.

J R Stat Soc Ser A Stat Soc 2009 Oct;172(4):729-748

National Cancer Institute, Bethesda, USA.

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http://dx.doi.org/10.1111/j.1467-985X.2009.00592.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804257PMC
October 2009

Cancer screening: the clash of science and intuition.

Annu Rev Med 2009 ;60:125-37

Office of Disease Prevention, Office of the Director, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1146/annurev.med.60.101107.134802DOI Listing
September 2009

Clinical trial design and evidence-based outcomes in the study of liver diseases.

J Hepatol 2009 Apr 4;50(4):817-26. Epub 2009 Feb 4.

National Institutes of Health, Office of Disease Prevention, 6100 Executive Blvd, Suite 2B-03 Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.jhep.2009.01.005DOI Listing
April 2009

Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats.

BMC Cancer 2009 Mar 23;9:89. Epub 2009 Mar 23.

Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, USA.

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http://dx.doi.org/10.1186/1471-2407-9-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663766PMC
March 2009

Early reporting for cancer screening trials.

J Med Screen 2008 ;15(3):122-9

Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1258/jms.2008.007058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586667PMC
February 2009

Using microarrays to study the microenvironment in tumor biology: the crucial role of statistics.

Semin Cancer Biol 2008 Oct 26;18(5):305-10. Epub 2008 Mar 26.

Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1016/j.semcancer.2008.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584335PMC
October 2008

Estimating the cumulative risk of a false-positive under a regimen involving various types of cancer screening tests.

J Med Screen 2008 ;15(1):18-22

Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd. MSC 7354, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1258/jms.2008.007076DOI Listing
July 2008

Randomized trials for the real world: making as few and as reasonable assumptions as possible.

Stat Methods Med Res 2008 Jun 9;17(3):243-52. Epub 2007 Oct 9.

Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1177/0962280207080640DOI Listing
June 2008

Design and endpoints of clinical trials in hepatocellular carcinoma.

J Natl Cancer Inst 2008 May 13;100(10):698-711. Epub 2008 May 13.

HCC Translational Research Lab, Barcelona Clínic Liver Cancer Group, Liver Unit, Hospital Clinic, CIBERehd, Institute for Biomedical Investigations August Pi Sunyer, Villarroel 170, 08036 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1093/jnci/djn134DOI Listing
May 2008

Overstating the evidence for lung cancer screening: the International Early Lung Cancer Action Program (I-ELCAP) study.

Arch Intern Med 2007 Nov;167(21):2289-95

VA Outcomes Group, White River Junction VA Medical Center, 215 N Main St, VA Outcomes Group, 11B, White River Junction, VT 05009, USA.

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http://dx.doi.org/10.1001/archinte.167.21.2289DOI Listing
November 2007

Screening for prostate cancer: current status and future prospects.

Am J Med 2007 Sep;120(9):743-5

Medical Oncology Branch, National Cancer Institute, Bethesda, Md, USA.

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http://dx.doi.org/10.1016/j.amjmed.2006.12.014DOI Listing
September 2007

Paradoxes in carcinogenesis: new opportunities for research directions.

BMC Cancer 2007 Aug 6;7:151. Epub 2007 Aug 6.

Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1186/1471-2407-7-151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1993836PMC
August 2007

Repeat prostate biopsy in the prostate, lung, colorectal and ovarian cancer screening trial.

BJU Int 2007 Apr 12;99(4):775-9. Epub 2007 Jan 12.

Division of Cancer Prevention, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/j.1464-410X.2007.06708.xDOI Listing
April 2007

Prostate-specific antigen velocity and prostate cancer gleason grade and stage.

Cancer 2007 Apr;109(8):1689-95

Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/cncr.22558DOI Listing
April 2007

Identifying genes that contribute most to good classification in microarrays.

BMC Bioinformatics 2006 Sep 7;7:407. Epub 2006 Sep 7.

Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892-7354, USA.

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http://dx.doi.org/10.1186/1471-2105-7-407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574352PMC
September 2006