Barbara van Loon

Barbara van Loon

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Barbara van Loon

Barbara van Loon

Publications by authors named "Barbara van Loon"

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Characterization of FGD5 Expression in Primary Breast Cancers and Lymph Node Metastases.

J Histochem Cytochem 2018 11 27;66(11):787-799. Epub 2018 Jul 27.

Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1369/0022155418792032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213565PMC
November 2018

Living on the Edge: DNA Polymerase Lambda between Genome Stability and Mutagenesis.

Chem Res Toxicol 2017 11 8;30(11):1936-1941. Epub 2017 Sep 8.

DNA Enzymology & Molecular Virology and Cell Nucleus & DNA replication Units, Institute of Molecular Genetics IGM-CNR , via Abbiategrasso 207, I-27100 Pavia, Italy.

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http://dx.doi.org/10.1021/acs.chemrestox.7b00152DOI Listing
November 2017

Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity.

Nucleic Acids Res 2017 03;45(5):2600-2614

DNA Enzymology & Molecular Virology and Cell Nucleus & DNA replication Units, Institute of Molecular Genetics IGM-CNR, via Abbiategrasso 207, I-27100 Pavia, Italy.

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http://dx.doi.org/10.1093/nar/gkw1275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389505PMC
March 2017

Bypass of Mutagenic O(6)-Carboxymethylguanine DNA Adducts by Human Y- and B-Family Polymerases.

Chem Res Toxicol 2016 09 24;29(9):1493-503. Epub 2016 Aug 24.

Department of Health Sciences and Technology, ETH Zürich , Schmelzbergstrasse 9, 8092 Zürich, Switzerland.

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http://dx.doi.org/10.1021/acs.chemrestox.6b00168DOI Listing
September 2016

Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair.

Nat Commun 2016 Feb 26;7:10805. Epub 2016 Feb 26.

DNA Enzymology &Molecular Virology Unit, Institute of Molecular Genetics IGM-CNR, via Abbiategrasso 207, I-27100 Pavia, Italy.

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http://dx.doi.org/10.1038/ncomms10805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773436PMC
February 2016

The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants.

DNA Repair (Amst) 2015 Nov 14;35:13-8. Epub 2015 Sep 14.

Institute of Veterinary Biochemistry and Molecular Biology, University of Zürich, Winterthurerstrasse 190, 8057 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2015.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206904PMC
November 2015

DNA polymerases: Biology, diseases and biomedical applications.

DNA Repair (Amst) 2015 May;29:1-3

Institute of Veterinary Biochemistry and Molecular Biology, University of Zürich-Irchel, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.dnarep.2015.04.001DOI Listing
May 2015

Nucleotides with altered hydrogen bonding capacities impede human DNA polymerase η by reducing synthesis in the presence of the major cisplatin DNA adduct.

J Am Chem Soc 2015 Apr 6;137(14):4728-34. Epub 2015 Apr 6.

§Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, 8092 Zürich, Switzerland.

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http://pubs.acs.org/doi/10.1021/ja512547g
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http://dx.doi.org/10.1021/ja512547gDOI Listing
April 2015

Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication.

Virol J 2015 Feb 1;12. Epub 2015 Feb 1.

UiT - The Arctic University of Norway, Faculty of Health Sciences, Department of Medical Biology, Molecular Inflammation Research Group, Tromsø NO-9037, Norway.

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http://dx.doi.org/10.1186/s12985-014-0220-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318453PMC
February 2015

DNA damage response and DNA repair - dog as a model?

BMC Cancer 2014 Mar 19;14:203. Epub 2014 Mar 19.

Division of Radiation Oncology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1186/1471-2407-14-203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995094PMC
March 2014

Handling the 3-methylcytosine lesion by six human DNA polymerases members of the B-, X- and Y-families.

Nucleic Acids Res 2014 Jan 4;42(1):553-66. Epub 2013 Oct 4.

Institute of Veterinary Biochemistry and Molecular Biology, University of Zürich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.

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http://dx.doi.org/10.1093/nar/gkt889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874200PMC
January 2014

DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass.

Proc Natl Acad Sci U S A 2013 Nov 4;110(47):18850-5. Epub 2013 Nov 4.

Institute of Molecular Genetics-Consiglio Nazionale delle Ricerche, I-27100 Pavia, Italy.

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http://dx.doi.org/10.1073/pnas.1308760110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839753PMC
November 2013

The human Tim-Tipin complex interacts directly with DNA polymerase epsilon and stimulates its synthetic activity.

J Biol Chem 2013 May 19;288(18):12742-52. Epub 2013 Mar 19.

Istituto di Biochimica delle Proteine, Consiglio Nazionale delle Ricerche, Via P. Castellino 111, 80131 Naples, Italy.

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http://dx.doi.org/10.1074/jbc.M112.398073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642320PMC
May 2013

Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB).

DNA Repair (Amst) 2013 Mar 3;12(3):177-87. Epub 2013 Jan 3.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.dnarep.2012.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998512PMC
March 2013

Base excision repair in physiology and pathology of the central nervous system.

Int J Mol Sci 2012 Nov 30;13(12):16172-222. Epub 2012 Nov 30.

Institute for Veterinary Biochemistry and Molecular Biology, University of Zürich-Irchel, Winterthurerstrasse 190, 8057 Zürich, Switzerland.

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http://dx.doi.org/10.3390/ijms131216172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546685PMC
November 2012

Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage.

Nucleic Acids Res 2012 Sep 29;40(17):8449-59. Epub 2012 Jun 29.

Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

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http://dx.doi.org/10.1093/nar/gks648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458577PMC
September 2012

Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem.

Cell Cycle 2012 Mar 15;11(6):1070-5. Epub 2012 Mar 15.

Institute for Veterinary Biochemistry and Molecular Biology; University of Zürich-Irchel; Zürich, Switzerland.

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http://dx.doi.org/10.4161/cc.11.6.19448DOI Listing
March 2012

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.

Proc Natl Acad Sci U S A 2012 Jan 27;109(2):437-42. Epub 2011 Dec 27.

Institute for Veterinary Biochemistry and Molecular Biology, University of Zürich-Irchel, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.

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http://dx.doi.org/10.1073/pnas.1110449109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258598PMC
January 2012

Ubiquitylation of DNA polymerase λ.

FEBS Lett 2011 Sep 8;585(18):2826-30. Epub 2011 Apr 8.

Institute for Veterinary Biochemistry and Molecular Biology, University of Zürich-Irchel, Winterthurerstrasse 190, 8057 Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.febslet.2011.03.069DOI Listing
September 2011

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine.

DNA Repair (Amst) 2010 Jun;9(6):604-16

Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.dnarep.2010.03.004DOI Listing
June 2010

An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda.

Proc Natl Acad Sci U S A 2009 Oct 9;106(43):18201-6. Epub 2009 Oct 9.

Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

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http://dx.doi.org/10.1073/pnas.0907280106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775316PMC
October 2009

Isolation of recombinant DNA elongation proteins.

Methods Mol Biol 2009 ;521:345-59

Institute of Veterinary Biochemistry and Molecular Biology, University of Zürich-Irchel, Zürich, Switzerland.

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http://dx.doi.org/10.1007/978-1-60327-815-7_19DOI Listing
August 2009

The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1.

J Biol Chem 2009 May 27;284(21):14267-75. Epub 2009 Mar 27.

Institute of Molecular Genetics National Research Council, via Abbiategrasso 207, I-27100 Pavia, Italy.

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http://dx.doi.org/10.1074/jbc.M900759200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682875PMC
May 2009

Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair.

Proc Natl Acad Sci U S A 2008 Dec 22;105(52):20689-94. Epub 2008 Dec 22.

Institute of Molecular Genetics, Consiglio Nazionale delle Ricerche, Via Abbiategrasso 207, I-27100 Pavia, Italy.

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http://dx.doi.org/10.1073/pnas.0811241106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634905PMC
December 2008

The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase delta.

Nucleic Acids Res 2008 Sep 5;36(16):5166-79. Epub 2008 Aug 5.

Institute of Veterinary Biochemistry and Molecular Biology, University of Zürich, Winterthurerstr. 190, CH-8057 Zürich, Switzerland.

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http://dx.doi.org/10.1093/nar/gkn498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532730PMC
September 2008