Barbara Laughton

Barbara Laughton

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Barbara Laughton

Barbara Laughton

Publications by authors named "Barbara Laughton"

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Diagnostic accuracy of the Molteno Adapted Scale for developmental delay in South African toddlers.

Paediatr Int Child Health 2019 05 17;39(2):132-138. Epub 2018 Oct 17.

a Department of Psychology , Stellenbosch University , Matieland , South Africa.

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http://dx.doi.org/10.1080/20469047.2018.1528754DOI Listing
May 2019

Should efavirenz be used in children and, if so, how?

Lancet HIV 2019 Apr 12;6(4):e210-e211. Epub 2019 Feb 12.

Department of Paediatrics and Child Health FAM-CRU, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1016/S2352-3018(18)30337-0DOI Listing
April 2019

Five year neurodevelopment outcomes of perinatally HIV-infected children on early limited or deferred continuous antiretroviral therapy.

J Int AIDS Soc 2018 05;21(5):e25106

Family Clinical Research Unit, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1002/jia2.25106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932637PMC
May 2018

Perinatal HIV Infection or Exposure Is Associated With Low -Acetylaspartate and Glutamate in Basal Ganglia at Age 9 but Not 7 Years.

Front Hum Neurosci 2018 7;12:145. Epub 2018 May 7.

Medical Imaging Research Unit, Division of Biomedical Engineering, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fnhum.2018.00145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949349PMC
May 2018

Altered brain morphometry in 7-year old HIV-infected children on early ART.

Metab Brain Dis 2018 04 5;33(2):523-535. Epub 2017 Dec 5.

MRC/UCT Medical Imaging Research Unit, Division of Biomedical Engineering, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s11011-017-0162-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866746PMC
April 2018

Favourable outcome in a child with symptomatic diagnosis of Glutaric aciduria type 1 despite vertical HIV infection and minor head trauma.

Metab Brain Dis 2018 04 9;33(2):537-544. Epub 2018 Feb 9.

Family Clinical Research Unit, Department of Paediatrics and Child Health, Tygerberg Hospital and Stellenbosch University, Francie van Zijl Drive, Tygerberg, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s11011-018-0196-4DOI Listing
April 2018

Neurodevelopmental outcome of HIV-exposed but uninfected infants in the Mother and Infants Health Study, Cape Town, South Africa.

Trop Med Int Health 2018 01 7;23(1):69-78. Epub 2017 Dec 7.

Department of Paediatrics & Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1111/tmi.13006DOI Listing
January 2018

Functional Connectivity Alterations between Networks and Associations with Infant Immune Health within Networks in HIV Infected Children on Early Treatment: A Study at 7 Years.

Front Hum Neurosci 2017 11;11:635. Epub 2018 Jan 11.

MRC/UCT Medical Imaging Research Unit, Division of Biomedical Engineering, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fnhum.2017.00635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768628PMC
January 2018

Late-Onset Hiv Encephalopathy In Children With Long-Standing Virologic Suppression Followed By Slow Spontaneous Recovery Despite no Change In Antiretroviral Therapy: 4 Case Reports.

Pediatr Infect Dis J 2017 Nov;36(11):e264-e267

From the *Children's Infectious Diseases Clinical Research Unit (KID-CRU), Stellenbosch University, and †Department of Paediatrics and Child Health, Tygerberg Children's Hospital, Cape Town, South Africa; ‡Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Soweto, South Africa; and §Division of Medical Virology, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1097/INF.0000000000001694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638699PMC
November 2017

Larger Subcortical Gray Matter Structures and Smaller Corpora Callosa at Age 5 Years in HIV Infected Children on Early ART.

Front Neuroanat 2017 2;11:95. Epub 2017 Nov 2.

MRC/UCT Medical Imaging Research Unit, Division of Biomedical Engineering, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fnana.2017.00095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673662PMC
November 2017

Longitudinal increases of brain metabolite levels in 5-10 year old children.

PLoS One 2017 11;12(7):e0180973. Epub 2017 Jul 11.

MRC/UCT Medical Imaging Research Unit, Division of Biomedical Engineering, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180973PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507439PMC
September 2017

White Matter Abnormalities in Children with HIV Infection and Exposure.

Front Neuroanat 2017 29;11:88. Epub 2017 Sep 29.

Division of Biomedical Engineering, Department of Human Biology, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fnana.2017.00088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627060PMC
September 2017

HIV encephalopathy with bilateral lower limb spasticity: upper limb motor function and level of activity and participation.

Dev Med Child Neurol 2017 04 30;59(4):412-419. Epub 2016 Aug 30.

Division of Neurosurgery, Department of Surgery, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1111/dmcn.13236DOI Listing
April 2017

HIV encephalopathy with bilateral lower limb spasticity: gross motor function and antiretroviral therapy.

Dev Med Child Neurol 2017 04 23;59(4):407-411. Epub 2017 Jan 23.

Division of Neurosurgery, Department of Surgery, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1111/dmcn.13377DOI Listing
April 2017

Assessing the performance of different DTI motion correction strategies in the presence of EPI distortion correction.

Hum Brain Mapp 2016 12 20;37(12):4405-4424. Epub 2016 Jul 20.

Department of Human Biology, Faculty of Health Sciences, MRC/UCT Medical Imaging Research Unit, University of Cape Town, South Africa.

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http://dx.doi.org/10.1002/hbm.23318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118068PMC
December 2016

HIV-associated CD4+/CD8+ depletion in infancy is associated with neurometabolic reductions in the basal ganglia at age 5 years despite early antiretroviral therapy.

AIDS 2016 06;30(9):1353-62

aMRC/UCT Medical Imaging Research Unit, Department of Human Biology, Faculty of Health Sciences, University of Cape Town bChildren's Infectious Diseases Clinical Research Unit, Department of Paediatrics & Child Health, Tygerberg Children's Hospital and Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa cA.A. Martinos Centre for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown dDepartment of Radiology, Harvard Medical School, Boston, Massachusetts, USA eDepartment of Statistical Sciences, Faculty of Sciences, University of Cape Town, South Africa fOxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1097/QAD.0000000000001082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864158PMC
June 2016

Hearing assessment data in HIV-infected and uninfected children of Cape Town, South Africa.

AIDS Care 2015 11;27(8):1037-41. Epub 2015 Mar 11.

a School of Speech, Language, and Hearing Sciences , San Diego State University , San Diego , CA , USA.

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http://dx.doi.org/10.1080/09540121.2015.1021746DOI Listing
January 2016

Corpus callosum thickness on mid-sagittal MRI as a marker of brain volume: a pilot study in children with HIV-related brain disease and controls.

Pediatr Radiol 2015 Jul 27;45(7):1016-25. Epub 2015 Jan 27.

Department of Radiology, Faculty of Health Sciences, University of the Witwatersrand, South Africa, 700 Harbouredge, 10 Hospital Str. Greenpoint, Cape Town, 8005, South Africa,

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http://link.springer.com/10.1007/s00247-014-3255-y
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http://dx.doi.org/10.1007/s00247-014-3255-yDOI Listing
July 2015

Motion artifact reduction in pediatric diffusion tensor imaging using fast prospective correction.

J Magn Reson Imaging 2015 May 17;41(5):1353-64. Epub 2014 Jun 17.

MRC/UCT Medical Imaging Research Unit, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, South Africa.

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http://dx.doi.org/10.1002/jmri.24678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269573PMC
May 2015

Quality of 186 child brain spectra using motion and B0 shim navigated single voxel spectroscopy.

J Magn Reson Imaging 2014 Oct 4;40(4):958-65. Epub 2013 Nov 4.

Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/jmri.24436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059781PMC
October 2014

Correlating brain volume and callosal thickness with clinical and laboratory indicators of disease severity in children with HIV-related brain disease.

Childs Nerv Syst 2014 Sep 23;30(9):1549-57. Epub 2014 May 23.

Department of Radiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa,

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http://dx.doi.org/10.1007/s00381-014-2434-3DOI Listing
September 2014

White matter signal abnormalities in children with suspected HIV-related neurologic disease on early combination antiretroviral therapy.

Pediatr Infect Dis J 2014 Aug;33(8):e207-12

From the *Department of Radiology, Stellenbosch University, Tygerberg; †Department of Radiology, University of Witwatersrand, Johannesburg, Gauteng; ‡Children's Infectious Diseases Clinical Research Unit, Stellenbosch University; §Tygerberg Children's Hospital; ¶Centre for Statistical Consultation and ‖Department of Paediatrics and Child Health, Stellenbosch University, Tygerberg, Cape Town, South Africa.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/INF.0000000000000288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153800PMC
August 2014

Spastic diplegia in children with HIV encephalopathy: first description of gait and physical status.

Dev Med Child Neurol 2014 Jul 3;56(7):686-94. Epub 2013 Nov 3.

Neurosurgery Division, Department of Surgery, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Physiotherapy Division, Department of Interdisciplinary Health Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.

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http://dx.doi.org/10.1111/dmcn.12319DOI Listing
July 2014

Neurodevelopment in perinatally HIV-infected children: a concern for adolescence.

J Int AIDS Soc 2013 Jun 18;16:18603. Epub 2013 Jun 18.

Children's Infectious Diseases Clinical Research Unit, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687073PMC
http://dx.doi.org/10.7448/IAS.16.1.18603DOI Listing
June 2013

Early antiretroviral therapy improves neurodevelopmental outcomes in infants.

AIDS 2012 Aug;26(13):1685-90

Children's Infectious Diseases Clinical Research Unit, Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Children's Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAD.0b013e328355d0ceDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145617PMC
August 2012