Barbara L Weber

Barbara L Weber

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Barbara L Weber

Barbara L Weber

Publications by authors named "Barbara L Weber"

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Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

Authors:
Christopher A Maxwell Javier Benítez Laia Gómez-Baldó Ana Osorio Núria Bonifaci Ricardo Fernández-Ramires Sylvain V Costes Elisabet Guinó Helen Chen Gareth J R Evans Pooja Mohan Isabel Català Anna Petit Helena Aguilar Alberto Villanueva Alvaro Aytes Jordi Serra-Musach Gad Rennert Flavio Lejbkowicz Paolo Peterlongo Siranoush Manoukian Bernard Peissel Carla B Ripamonti Bernardo Bonanni Alessandra Viel Anna Allavena Loris Bernard Paolo Radice Eitan Friedman Bella Kaufman Yael Laitman Maya Dubrovsky Roni Milgrom Anna Jakubowska Cezary Cybulski Bohdan Gorski Katarzyna Jaworska Katarzyna Durda Grzegorz Sukiennicki Jan Lubiński Yin Yao Shugart Susan M Domchek Richard Letrero Barbara L Weber Frans B L Hogervorst Matti A Rookus J Margriet Collee Peter Devilee Marjolijn J Ligtenberg Rob B van der Luijt Cora M Aalfs Quinten Waisfisz Juul Wijnen Cornelis E P van Roozendaal Douglas F Easton Susan Peock Margaret Cook Clare Oliver Debra Frost Patricia Harrington D Gareth Evans Fiona Lalloo Rosalind Eeles Louise Izatt Carol Chu Diana Eccles Fiona Douglas Carole Brewer Heli Nevanlinna Tuomas Heikkinen Fergus J Couch Noralane M Lindor Xianshu Wang Andrew K Godwin Maria A Caligo Grazia Lombardi Niklas Loman Per Karlsson Hans Ehrencrona Anna von Wachenfeldt Rosa Bjork Barkardottir Ute Hamann Muhammad U Rashid Adriana Lasa Trinidad Caldés Raquel Andrés Michael Schmitt Volker Assmann Kristen Stevens Kenneth Offit João Curado Hagen Tilgner Roderic Guigó Gemma Aiza Joan Brunet Joan Castellsagué Griselda Martrat Ander Urruticoechea Ignacio Blanco Laima Tihomirova David E Goldgar Saundra Buys Esther M John Alexander Miron Melissa Southey Mary B Daly Rita K Schmutzler Barbara Wappenschmidt Alfons Meindl Norbert Arnold Helmut Deissler Raymonda Varon-Mateeva Christian Sutter Dieter Niederacher Evgeny Imyamitov Olga M Sinilnikova Dominique Stoppa-Lyonne Sylvie Mazoyer Carole Verny-Pierre Laurent Castera Antoine de Pauw Yves-Jean Bignon Nancy Uhrhammer Jean-Philippe Peyrat Philippe Vennin Sandra Fert Ferrer Marie-Agnès Collonge-Rame Isabelle Mortemousque Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Sue Healey Mary Helen Barcellos-Hoff Marc Vidal Stephen B Gruber Conxi Lázaro Gabriel Capellá Lesley McGuffog Katherine L Nathanson Antonis C Antoniou Georgia Chenevix-Trench Markus C Fleisch Víctor Moreno Miguel Angel Pujana

PLoS Biol 2011 Nov 15;9(11):e1001199. Epub 2011 Nov 15.

Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute-IDIBELL, L'Hospitalet, Catalonia, Spain.

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http://dx.doi.org/10.1371/journal.pbio.1001199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217025PMC
November 2011

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

J Clin Invest 2010 May 12;120(5):1535-50. Epub 2010 Apr 12.

Department of Pathology, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1172/JCI39534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860938PMC
May 2010

Genome-wide DNA copy number predictors of lapatinib sensitivity in tumor-derived cell lines.

Mol Cancer Ther 2008 Apr;7(4):935-43

Translational Medicine Oncology, GlaxoSmithKline, 1250 South Collegeville Road, UP 4W-4230, Collegeville, PA 19426, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2072DOI Listing
April 2008

miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer.

Cancer Biol Ther 2008 Feb 14;7(2):255-64. Epub 2007 Nov 14.

Center for Research on Early Detection and Cure of Ovarian Cancer, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233968PMC
http://dx.doi.org/10.4161/cbt.7.2.5297DOI Listing
February 2008

Genetic variants of uncertain significance: flies in the ointment.

J Clin Oncol 2008 Jan;26(1):16-7

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http://dx.doi.org/10.1200/JCO.2007.14.4154DOI Listing
January 2008

A comparison of DNA copy number profiling platforms.

Cancer Res 2007 Nov 29;67(21):10173-80. Epub 2007 Oct 29.

Translational Medicine, GlaxoSmithKline, King of Prussia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-2102DOI Listing
November 2007

Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer.

Clin Cancer Res 2007 Sep;13(18 Pt 1):5314-21

Center for Research on Early Detection and Cure of Ovarian Cancer, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2660DOI Listing
September 2007

In the palace of the sultan: 2007 American Society for Clinical Investigation Presidential Address.

Authors:
Barbara L Weber

J Clin Invest 2007 Jun;117(6):1727-31

Discovery and Translational Medicine, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.

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http://dx.doi.org/10.1172/JCI32575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1878545PMC
June 2007

Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridization.

Cancer Res 2007 Apr;67(8):3594-600

Translational Medicine and Genetics, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-06-3674DOI Listing
April 2007

Multiple initial culture conditions enhance the establishment of cell lines from primary ovarian cancer specimens.

In Vitro Cell Dev Biol Anim 2006 Mar-Apr;42(3-4):58-62

Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1290/0512084.1DOI Listing
December 2006

The joint effect of smoking and AIB1 on breast cancer risk in BRCA1 mutation carriers.

Carcinogenesis 2006 Mar 22;27(3):599-605. Epub 2005 Oct 22.

Department of Biostatistics and Epidemiology and Medicine and Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/carcin/bgi246DOI Listing
March 2006

High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization.

Breast Cancer Res 2005 24;7(6):R1186-98. Epub 2005 Nov 24.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr1356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410746PMC
February 2006

Clinical management of BRCA1 and BRCA2 mutation carriers.

Nat Clin Pract Oncol 2006 Jan;3(1):2-3

Cancer Risk Evaluation Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19014, USA.

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http://dx.doi.org/10.1038/ncponc0384DOI Listing
January 2006

Measurement and relevance of neuroblastoma DNA copy number changes in the post-genome era.

Cancer Lett 2005 Oct;228(1-2):83-90

Division of Oncology, Children's Hospital of Philadelphia, Abramson Pediatric Research Center 902A, 3615 Civic Center Blvd, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1016/j.canlet.2005.02.052DOI Listing
October 2005

High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.

Genes Chromosomes Cancer 2005 Aug;43(4):390-403

Division of Oncology, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.

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http://dx.doi.org/10.1002/gcc.20198DOI Listing
August 2005

CGHAnalyzer: a stand-alone software package for cancer genome analysis using array-based DNA copy number data.

Bioinformatics 2005 Aug 19;21(15):3308-11. Epub 2005 May 19.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/bti500DOI Listing
August 2005

Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth.

Cancer Res 2005 Feb;65(3):925-32

Abramson Family Cancer Research Institute, Center for Research on Reproduction and Women's Health, University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, PA 19104, USA.

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February 2005

Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition.

Cancer Res 2004 Jun;64(11):3790-7

Laboratory of Molecular Biophysics, Pels Family Center for Biochemistry and Structural Biology, Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-03-3009DOI Listing
June 2004

Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.

J Clin Oncol 2004 Mar 23;22(6):1055-62. Epub 2004 Feb 23.

Center for Clinical Epidemiology and Biostatistics, Abramson Family Cancer Research Institute, The University of Pennsylvania, Philadelphia, PA 19104-6021, USA.

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http://ascopubs.org/doi/10.1200/JCO.2004.04.188
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http://dx.doi.org/10.1200/JCO.2004.04.188DOI Listing
March 2004

Computerized analysis of mammographic parenchymal patterns for assessing breast cancer risk: effect of ROI size and location.

Med Phys 2004 Mar;31(3):549-55

Department of Radiology, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1118/1.1644514DOI Listing
March 2004

MYC is amplified in BRCA1-associated breast cancers.

Clin Cancer Res 2004 Jan;10(2):499-507

Section of Hematology/Oncology, Department of Medicine, Committees on Genetics and Cancer Biology, University of Chicago, Chicago, Illinois 60637-1463, USA.

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http://dx.doi.org/10.1158/1078-0432.ccr-0976-03DOI Listing
January 2004

Identification and high-resolution mapping of a constitutional 11q deletion in an infant with multifocal neuroblastoma.

Lancet Oncol 2003 Dec;4(12):769-71

Division of Oncology, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4318, USA.

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http://dx.doi.org/10.1016/s1470-2045(03)01283-xDOI Listing
December 2003

BRAF as a potential therapeutic target in melanoma and other malignancies.

Cancer Cell 2003 Aug;4(2):95-8

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/s1535-6108(03)00189-2DOI Listing
August 2003

Breast and ovarian cancer.

N Engl J Med 2003 Jun;348(23):2339-47

Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.

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http://www.nejm.org/doi/10.1056/NEJMra012284
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http://dx.doi.org/10.1056/NEJMra012284DOI Listing
June 2003

Application of breast cancer risk prediction models in clinical practice.

J Clin Oncol 2003 Feb;21(4):593-601

University of Pennsylvania Cancer Center, 14 Penn Tower, 3400 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1200/JCO.2003.07.007DOI Listing
February 2003

BRAF and RAS mutations in human lung cancer and melanoma.

Cancer Res 2002 Dec;62(23):6997-7000

Department of Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania Cancer Center, Philadelphia 19104, USA.

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December 2002

Computerized analysis of digitized mammograms of BRCA1 and BRCA2 gene mutation carriers.

Radiology 2002 Nov;225(2):519-26

Department of Radiology, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA.

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http://pubs.rsna.org/doi/10.1148/radiol.2252010845
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http://dx.doi.org/10.1148/radiol.2252010845DOI Listing
November 2002

Recent advances in breast cancer biology.

Curr Opin Oncol 2002 Nov;14(6):589-93

Department Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/00001622-200211000-00001DOI Listing
November 2002

Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program.

J Natl Cancer Inst 2002 Sep;94(18):1365-72

Department of Medicine and Abramson Family Cancer Research Institute, University of Pennsylvania Cancer Center, Philadelphia 19104, USA.

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http://dx.doi.org/10.1093/jnci/94.18.1365DOI Listing
September 2002

CGH-targeted linkage analysis reveals a possible BRCA1 modifier locus on chromosome 5q.

Hum Mol Genet 2002 May;11(11):1327-32

Department of Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/hmg/11.11.1327DOI Listing
May 2002

Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations.

N Engl J Med 2002 May 20;346(21):1616-22. Epub 2002 May 20.

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA.

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http://dx.doi.org/10.1056/NEJMoa012158DOI Listing
May 2002

Molecular-cytogenetic analysis of HER-2/neu gene in BRCA1-associated breast cancers.

Cancer Res 2002 Mar;62(5):1481-8

Section of Hematology/Oncology, Department of Medicine, Committee on Genetics, University of Chicago, Chicago, Illinois 60637-1463, USA.

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March 2002

BRCA1 and BRCA2 mutation frequency in women evaluated in a breast cancer risk evaluation clinic.

J Clin Oncol 2002 Feb;20(4):994-9

Abramson Family Cancer Research Institute and Department of Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://ascopubs.org/doi/10.1200/JCO.2002.20.4.994
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http://dx.doi.org/10.1200/JCO.2002.20.4.994DOI Listing
February 2002

Cancer genomics.

Authors:
Barbara L Weber

Cancer Cell 2002 Feb;1(1):37-47

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia 19104, USA.

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http://dx.doi.org/10.1016/s1535-6108(02)00026-0DOI Listing
February 2002