Barbara K Felber

Barbara K Felber

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Barbara K Felber

Publications by authors named "Barbara K Felber"

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HIV vaccine: better to start together?

Lancet HIV 2019 Oct 7. Epub 2019 Oct 7.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1016/S2352-3018(19)30323-6DOI Listing
October 2019

Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity.

J Biol Chem 2019 03 22;294(12):4412-4424. Epub 2019 Jan 22.

From the Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599,

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http://dx.doi.org/10.1074/jbc.RA118.006193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433073PMC
March 2019

Neutrophil Vaccination Dynamics and Their Capacity To Mediate B Cell Help in Rhesus Macaques.

J Immunol 2018 10 14;201(8):2287-2302. Epub 2018 Sep 14.

Immune Biology of Retroviral Infection Section, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.4049/jimmunol.1800677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179953PMC
October 2018

Optimized administration of hetIL-15 expands lymphocytes and minimizes toxicity in rhesus macaques.

Cytokine 2018 08 7;108:213-224. Epub 2018 May 7.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2018.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657354PMC
August 2018

A new step towards an HIV/AIDS vaccine.

Lancet 2018 07 6;392(10143):192-194. Epub 2018 Jul 6.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute Frederick, MD, USA.

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http://dx.doi.org/10.1016/S0140-6736(18)31548-4DOI Listing
July 2018

HIV Env conserved element DNA vaccine alters immunodominance in macaques.

Hum Vaccin Immunother 2017 12 5;13(12):2859-2871. Epub 2017 Jul 5.

a Human Retrovirus Pathogenesis Section, Center for Cancer Research, National Cancer Institute at Frederick , Frederick , MD , USA.

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http://dx.doi.org/10.1080/21645515.2017.1339852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718827PMC
December 2017

Modulation of Interleukin-12 activity in the presence of heparin.

Sci Rep 2017 07 13;7(1):5360. Epub 2017 Jul 13.

Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR, USA.

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http://dx.doi.org/10.1038/s41598-017-05382-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509706PMC
July 2017

Expression of complete SIV p27 Gag and HIV gp120 engineered outer domains targeted by broadly neutralizing antibodies in live rubella vectors.

Vaccine 2017 05 5;35(24):3272-3278. Epub 2017 May 5.

Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.04.047DOI Listing
May 2017

Efficient production and enhanced tumor delivery of engineered extracellular vesicles.

Biomaterials 2016 10 6;105:195-205. Epub 2016 Jul 6.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, United States. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.07.003DOI Listing
October 2016

DNA is an efficient booster of dendritic cell-based vaccine.

Hum Vaccin Immunother 2015 ;11(8):1927-35

a Human Retrovirus Section; Vaccine Branch; Center for Cancer Research; National Cancer Institute ; Frederick , MD USA.

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http://dx.doi.org/10.1080/21645515.2015.1020265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635890PMC
May 2016

Dose-dependent inhibition of Gag cellular immunity by Env in SIV/HIV DNA vaccinated macaques.

Hum Vaccin Immunother 2015 ;11(8):2005-11

a Human Retrovirus Section; Vaccine Branch; Center for Cancer Research; National Cancer Institute at Frederick ; Frederick , MD USA.

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http://dx.doi.org/10.1080/21645515.2015.1016671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635869PMC
May 2016

Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.

J Virol 2015 Aug 27;89(16):8643-50. Epub 2015 May 27.

Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA Department of Immunology, Duke University Medical Center, Durham, North Carolina, USA Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA

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http://dx.doi.org/10.1128/JVI.03635-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524233PMC
August 2015

HIV-1 conserved elements p24CE DNA vaccine induces humoral immune responses with broad epitope recognition in macaques.

PLoS One 2014 22;9(10):e111085. Epub 2014 Oct 22.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111085PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206485PMC
July 2015

Recombinant rubella vectors elicit SIV Gag-specific T cell responses with cytotoxic potential in rhesus macaques.

Vaccine 2015 Apr 21;33(18):2167-74. Epub 2015 Mar 21.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.02.067DOI Listing
April 2015

The "complex" RNA post-transcriptional element of a "simple" retrovirus.

Mob Genet Elements 2015 Mar-Apr;5(2):1-4. Epub 2015 Mar 16.

RT Biochemistry Section; Basic Research Laboratory; National Cancer Institute Frederick ; Frederick, MD USA.

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http://dx.doi.org/10.1080/2159256X.2015.1017085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588558PMC
March 2015

Gammaretrovirus mRNA expression is mediated by a novel, bipartite post-transcriptional regulatory element.

Nucleic Acids Res 2014 4;42(17):11092-106. Epub 2014 Sep 4.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA

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http://dx.doi.org/10.1093/nar/gku798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176177PMC
February 2015

Differential effects of IL-15 on the generation, maintenance and cytotoxic potential of adaptive cellular responses induced by DNA vaccination.

Vaccine 2015 Feb 2;33(9):1188-96. Epub 2015 Jan 2.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X140170
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http://dx.doi.org/10.1016/j.vaccine.2014.12.046DOI Listing
February 2015

DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.

J Med Primatol 2014 Oct 9;43(5):329-40. Epub 2014 May 9.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.

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http://doi.wiley.com/10.1111/jmp.12123
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http://dx.doi.org/10.1111/jmp.12123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176517PMC
October 2014

Improved flow-based method for HIV/SIV envelope-specific memory B-cell evaluation in rhesus macaques.

J Immunol Methods 2014 Oct 19;412:78-84. Epub 2014 Jun 19.

Section on Immune Biology of Retroviral Infection, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2014.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198494PMC
October 2014

HIV DNA Vaccine: Stepwise Improvements Make a Difference.

Vaccines (Basel) 2014 May 14;2(2):354-79. Epub 2014 May 14.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, P.O. Box B, Frederick, MD 21702, USA.

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http://dx.doi.org/10.3390/vaccines2020354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494255PMC
May 2014

Oral delivery of IL-27 recombinant bacteria attenuates immune colitis in mice.

Gastroenterology 2014 Jan 9;146(1):210-221.e13. Epub 2013 Oct 9.

Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085130143
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http://dx.doi.org/10.1053/j.gastro.2013.09.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920828PMC
January 2014

Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques.

Retrovirology 2013 Sep 16;10:99. Epub 2013 Sep 16.

Lab of Immunoregulation, Division of Viral Products, Office of Vaccines, Center for Biologics, FDA, NIH Campus, Bethesda, MD 20892, USA.

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http://retrovirology.biomedcentral.com/articles/10.1186/1742
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http://dx.doi.org/10.1186/1742-4690-10-99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849444PMC
September 2013

HIV/SIV DNA vaccine combined with protein in a co-immunization protocol elicits highest humoral responses to envelope in mice and macaques.

Vaccine 2013 Aug 26;31(36):3747-55. Epub 2013 Apr 26.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1016/j.vaccine.2013.04.037DOI Listing
August 2013

Kaposi's sarcoma-associated herpesvirus ORF57 is not a bona fide export factor.

J Virol 2012 Dec 19;86(23):13089-94. Epub 2012 Sep 19.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.

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http://dx.doi.org/10.1128/JVI.00606-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497679PMC
December 2012

Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.

J Virol 2011 Feb 24;85(4):1528-40. Epub 2010 Nov 24.

Tumor Virus RNA Biology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1128/JVI.01709-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028919PMC
February 2011

Nuclear export factor RBM15 facilitates the access of DBP5 to mRNA.

Nucleic Acids Res 2009 Nov;37(21):7151-62

Human Retrovirus Pathogenesis Section, National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA.

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http://dx.doi.org/10.1093/nar/gkp782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790900PMC
November 2009

The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.

J Biol Chem 2009 Sep 8;284(38):26106-16. Epub 2009 Jul 8.

Human Retrovirus Section, Center for Cancer Research, NCI, National Institutes of Health, Frederick, Maryland 21702-1201, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.040113
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http://dx.doi.org/10.1074/jbc.M109.040113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758010PMC
September 2009

Secretion and biological activity of short signal peptide IL-15 is chaperoned by IL-15 receptor alpha in vivo.

J Immunol 2009 Sep;183(5):3064-72

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702-1201, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0900693
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http://dx.doi.org/10.4049/jimmunol.0900693DOI Listing
September 2009

Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation.

Vaccine 2008 Sep 21;26(40):5223-9. Epub 2008 Apr 21.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702-1201, United States.

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http://dx.doi.org/10.1016/j.vaccine.2008.03.090DOI Listing
September 2008

The RNA transport element RTE is essential for IAP LTR-retrotransposon mobility.

Virology 2008 Jul 15;377(1):88-99. Epub 2008 May 15.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA.

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http://dx.doi.org/10.1016/j.virol.2008.04.002DOI Listing
July 2008

Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity.

J Biol Chem 2008 Feb 30;283(7):4189-99. Epub 2007 Nov 30.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, NCI-Frederick, National Instsitutes of Health, MD 21702-1201, USA.

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http://dx.doi.org/10.1074/jbc.M705725200DOI Listing
February 2008

Efficient systemic expression of bioactive IL-15 in mice upon delivery of optimized DNA expression plasmids.

DNA Cell Biol 2007 Dec;26(12):827-40

Human Retrovirus Pathogenesis Section, Vaccine Branch, National Cancer Institute-Frederick, Frederick, Maryland 21702-1201, USA.

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http://dx.doi.org/10.1089/dna.2007.0645DOI Listing
December 2007

Posttranscriptional control of HIV-1 and other retroviruses and its practical applications.

Adv Pharmacol 2007 ;55:161-97

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD 21702, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S105435890755005
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http://dx.doi.org/10.1016/S1054-3589(07)55005-2DOI Listing
August 2007

Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector.

Virology 2007 Jan 22;357(2):186-98. Epub 2006 Sep 22.

Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004268220600572
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http://dx.doi.org/10.1016/j.virol.2006.08.015DOI Listing
January 2007

Immunogenicity testing of a novel engineered HIV-1 envelope gp140 DNA vaccine construct.

DNA Cell Biol 2006 Jul;25(7):383-92

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6100, USA.

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http://dx.doi.org/10.1089/dna.2006.25.383DOI Listing
July 2006

Long lasting control and lack of pathogenicity of the attenuated Rev-independent SIV in rhesus macaques.

AIDS Res Hum Retroviruses 2006 Jun;22(6):516-28

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1089/aid.2006.22.516DOI Listing
June 2006

Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.

J Biol Chem 2005 Sep 12;280(36):31981-90. Epub 2005 Jul 12.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, NCI-Frederick, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1074/jbc.M502736200DOI Listing
September 2005

Identification and characterization of the mouse nuclear export factor (Nxf) family members.

Nucleic Acids Res 2005 13;33(12):3855-65. Epub 2005 Jul 13.

Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute Frederick, MD 21702-1201, USA.

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https://nar.oxfordjournals.org/content/33/12/3855.full-text-
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gki706
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http://dx.doi.org/10.1093/nar/gki706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175460PMC
July 2005