Barbara Casadei

Barbara Casadei

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Barbara Casadei

Barbara Casadei

Publications by authors named "Barbara Casadei"

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Sex differences in quality indicator attainment for myocardial infarction: a nationwide cohort study.

Heart 2019 04 23;105(7):516-523. Epub 2018 Nov 23.

Department of Clinical and Population Sciences, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1136/heartjnl-2018-313959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580739PMC
April 2019

Death from stroke in Europe: if you can't measure it, you can't improve it.

Eur Heart J 2019 Mar;40(9):765-767

Division of Cardiovascular Medicine, British Heart Foundation Centre of Research Excellence, University of Oxford & NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, UK.

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http://dx.doi.org/10.1093/eurheartj/ehy543DOI Listing
March 2019

Leaders in Cardiovascular Research: Barbara Casadei.

Cardiovasc Res 2019 Feb;115(2):e17-e19

University of Oxford, Oxford, Oxon, UK.

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https://academic.oup.com/cardiovascres/article/115/2/e17/529
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http://dx.doi.org/10.1093/cvr/cvy303DOI Listing
February 2019

What matters in Cardiovascular Research? Scientific discovery driving clinical delivery.

Cardiovasc Res 2018 Oct;114(12):1565-1568

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, UK.

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https://academic.oup.com/cardiovascres/article/114/12/1565/5
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http://dx.doi.org/10.1093/cvr/cvy214DOI Listing
October 2018

Hypertrophic cardiomyopathy mutations increase myofilament Ca buffering, alter intracellular Ca handling, and stimulate Ca-dependent signaling.

J Biol Chem 2018 07 14;293(27):10487-10499. Epub 2018 May 14.

From the Cardiovascular Medicine Division, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1074/jbc.RA118.002081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036197PMC
July 2018

From ionic to cellular variability in human atrial myocytes: an integrative computational and experimental study.

Am J Physiol Heart Circ Physiol 2018 05 22;314(5):H895-H916. Epub 2017 Dec 22.

Department of Computer Science, University of Oxford , Oxford , United Kingdom.

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http://dx.doi.org/10.1152/ajpheart.00477.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008144PMC
May 2018

Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine.

Cardiovasc Res 2018 Mar;114(3):417-430

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, BHF Centre of Research Excellence at the University of Oxford and the Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1093/cvr/cvx242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982714PMC
March 2018

Rivaroxaban in Stable Cardiovascular Disease.

N Engl J Med 2018 01;378(4):397

University of Oxford, Oxford, United Kingdom

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http://www.nejm.org/doi/10.1056/NEJMc1714934
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http://dx.doi.org/10.1056/NEJMc1714934DOI Listing
January 2018

Structure and Function of the Left Atrium and Left Atrial Appendage: AF and Stroke Implications.

J Am Coll Cardiol 2017 12;70(25):3157-3172

Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.10.063DOI Listing
December 2017

Seek and Ye Shall Find Subclinical Atrial Fibrillation in High-Risk Elderly Patients.

Circulation 2017 10;136(14):1284-1287

From Division of Cardiovascular Medicine, University of Oxford, UK.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029397DOI Listing
October 2017

Endogenous nitric oxide formation in cardiac myocytes does not control respiration during β-adrenergic stimulation.

J Physiol 2017 06 14;595(12):3781-3798. Epub 2017 May 14.

Klinik für Innere Medizin III, Universitätsklinikum des Saarlandes, 66421, Homburg, Germany.

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http://dx.doi.org/10.1113/JP273750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471411PMC
June 2017

Blood Pressure in Healthy Humans Is Regulated by Neuronal NO Synthase.

Hypertension 2017 05 6;69(5):970-976. Epub 2017 Mar 6.

From the King's College London British Heart Foundation Centre, Cardiovascular Division, United Kingdom (H.S., S.K., B.J., S.B., N.M., P.J.C., A.M.S.); and Department of Cardiovascular Medicine, University of Oxford, United Kingdom (B.C.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389591PMC
May 2017

The Subcellular Localisation of Neuronal Nitric Oxide Synthase Determines the Downstream Effects of NO on Myocardial Function.

Cardiovasc Res 2017 Feb 1. Epub 2017 Feb 1.

From the Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1093/cvr/cvx002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408949PMC
February 2017

Lone Atrial Fibrillation Is Associated With Impaired Left Ventricular Energetics That Persists Despite Successful Catheter Ablation.

Circulation 2016 Oct 14;134(15):1068-1081. Epub 2016 Sep 14.

From Division of Cardiovascular Medicine, University of Oxford, Oxford, UK (R.S.W., A.L., C.E., R.A., E.L., W.T.C., C.T.R., T.D.K., V.M.F., S.N., B.C.); University of Oxford Centre for Clinical Magnetic Resonance Research, Oxford, UK (R.S.W., A.L., C.E., R.A., E.L., W.T.C., C.T.R., T.D.K., V.M.F., S.N.); and Oxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK (Y.B., M.G., K.R., T.B.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054971PMC
http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022931DOI Listing
October 2016

Perioperative Rosuvastatin in Cardiac Surgery.

N Engl J Med 2016 09;375(9):903

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http://dx.doi.org/10.1056/NEJMc1608082DOI Listing
September 2016

Perioperative Rosuvastatin in Cardiac Surgery.

N Engl J Med 2016 May;374(18):1744-53

From the Department of Cardiovascular Surgery, State Key Laboratory of Cardiovascular Disease, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (Z.Z., L.J., Y.Z., Q.L., J.D., Z.C.); and the Division of Cardiovascular Medicine, Radcliffe Department of Medicine (R.J., S.G., B.C.), and the Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health (J.E., M.H., Z.C., R.C.), University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa1507750DOI Listing
May 2016

Compromised redox homeostasis, altered nitroso-redox balance, and therapeutic possibilities in atrial fibrillation.

Cardiovasc Res 2016 Apr 19;109(4):510-8. Epub 2016 Jan 19.

Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK

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http://dx.doi.org/10.1093/cvr/cvw012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777914PMC
April 2016

Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-γ/Adiponectin Signalling.

Circ Res 2016 Mar 21;118(5):842-55. Epub 2016 Jan 21.

From the Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom (A.S.A., M.M., A.R., F.S., L.H., C.P., P.C., I.A., A.T., B.C., K.M.C., C.A.); Cardiac Electrophysiology Group, Department of Physiology, Maastricht University, Maastricht, The Netherlands (S.V., H.N.); Department of Cardiology, Athens University Medical School, Athens, Greece (D.T.); Cardiovascular Division, King's College London BHF Centre, London, United Kingdom (A.C.B., A.M.S.); and Department of Cardiac Surgery, John Radcliffe Hospital, Oxford, United Kingdom (R.S., G.K., M.P.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772814PMC
March 2016

Systolic ShMOLLI myocardial T1-mapping for improved robustness to partial-volume effects and applications in tachyarrhythmias.

J Cardiovasc Magn Reson 2015 Aug 28;17:77. Epub 2015 Aug 28.

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, OX3 9DU, Oxford, UK.

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http://dx.doi.org/10.1186/s12968-015-0182-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552368PMC
August 2015

Atrial supply-demand mismatch in atrial fibrillation: The missing link between rapid rate and atrial remodeling?

Heart Rhythm 2015 May 28;12(5):1001-2. Epub 2015 Jan 28.

Division of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2015.01.036DOI Listing
May 2015

Catheter-based renal denervation reduces atrial nerve sprouting and complexity of atrial fibrillation in goats.

Circ Arrhythm Electrophysiol 2015 Apr 23;8(2):466-74. Epub 2015 Feb 23.

From the Universitätsklinikum des Saarlandes, Klinik für Innere Medizin III, Homburg/Saar, Germany (D.L., M.H., F.M., M.W., H.-R.N., M.B.); Department of Physiology, University Maastricht, Maastricht, The Netherlands (A.v. H., S.V., U.S.); Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom (B.C., S.N.R.).

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http://dx.doi.org/10.1161/CIRCEP.114.002453DOI Listing
April 2015

Atrial fibrillation: effects beyond the atrium?

Cardiovasc Res 2015 Mar 12;105(3):238-47. Epub 2015 Jan 12.

Division of Cardiovascular Medicine, BHF Centre of Research Excellence, University of Oxford, John Radcliffe Hospital, Level 6 West Wing, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1093/cvr/cvv001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339707PMC
March 2015

Molecular mechanisms of myocardial nitroso-redox imbalance during on-pump cardiac surgery.

Lancet 2015 Feb;385 Suppl 1:S49

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(15)60364-6DOI Listing
February 2015

Nitric oxide synthase regulation of cardiac excitation-contraction coupling in health and disease.

J Mol Cell Cardiol 2014 Aug 13;73:80-91. Epub 2014 Mar 13.

Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2014.03.004DOI Listing
August 2014

Targeting inflammation and oxidative stress in atrial fibrillation: role of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibition with statins.

Antioxid Redox Signal 2014 Mar 19;20(8):1268-85. Epub 2013 Oct 19.

1 Department of Cardiovascular Medicine, University of Oxford , John Radcliffe Hospital, Oxford, United Kingdom .

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http://dx.doi.org/10.1089/ars.2013.5542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934546PMC
March 2014

Bedside to bench: a look at experimental research with a clinical trial checklist.

Cardiovasc Res 2014 Jan;101(1):1-3

Department of Cardiovascular Sciences, KU Leuven, Herestraat 49, Leuven B-3000, Belgium.

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http://dx.doi.org/10.1093/cvr/cvt272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868353PMC
January 2014

Personalized management of atrial fibrillation: Proceedings from the fourth Atrial Fibrillation competence NETwork/European Heart Rhythm Association consensus conference.

Europace 2013 Nov 27;15(11):1540-56. Epub 2013 Aug 27.

University of Birmingham Centre for Cardiovascular Sciences and SWBH NHS Trust, Institute for Biomedical Research, 1st Floor, Room 136, Birmingham B15 2TT, UK.

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http://europace.oxfordjournals.org/content/europace/early/20
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http://europace.oxfordjournals.org/cgi/doi/10.1093/europace/
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http://dx.doi.org/10.1093/europace/eut232DOI Listing
November 2013

Differential role of endothelial versus neuronal nitric oxide synthase in the regulation of coronary blood flow during pacing-induced increases in cardiac workload.

Am J Physiol Heart Circ Physiol 2013 May 11;304(9):H1277-82. Epub 2013 Mar 11.

King's College London British Heart Foundation Centre, Cardiovascular Division, London, United Kingdom.

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http://dx.doi.org/10.1152/ajpheart.00927.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652090PMC
May 2013

Nitric oxide synthases in heart failure.

Antioxid Redox Signal 2013 Mar 20;18(9):1078-99. Epub 2012 Sep 20.

Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1089/ars.2012.4824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567782PMC
March 2013

Sub-cellular targeting of constitutive NOS in health and disease.

J Mol Cell Cardiol 2012 Feb 16;52(2):341-50. Epub 2011 Sep 16.

Department of Physiology, Seoul National University, College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.yjmcc.2011.09.006DOI Listing
February 2012

Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins.

Circulation 2011 Sep 15;124(10):1107-17. Epub 2011 Aug 15.

Department of Cardiovascular Medicine, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.029223DOI Listing
September 2011

Neuronal nitric oxide synthase and human vascular regulation.

Trends Cardiovasc Med 2009 Nov;19(8):256-62

King's College London British Heart Foundation Centre of Excellence, Cardiovascular Division, London, United Kingdom.

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http://dx.doi.org/10.1016/j.tcm.2010.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984617PMC
November 2009

The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium.

Biochim Biophys Acta 2009 Jul 8;1787(7):811-7. Epub 2009 Apr 8.

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S000527280900125
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http://dx.doi.org/10.1016/j.bbabio.2009.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791851PMC
July 2009

Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo.

Circulation 2009 May 11;119(20):2656-62. Epub 2009 May 11.

King's College London British Heart Foundation Centre, Cardiovascular Division, Department of Cardiology, London, UK.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.108.8
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http://dx.doi.org/10.1161/CIRCULATIONAHA.108.822205DOI Listing
May 2009

Beta 3-adrenoceptors modulate left ventricular relaxation in the rat heart via the NO-cGMP-PKG pathway.

Authors:
Barbara Casadei

Acta Physiol (Oxf) 2008 Jul;193(3):203

University Department of Cardiovascular Medicine John Radcliffe Hospital Oxford, UK.

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http://dx.doi.org/10.1111/j.1748-1716.2008.01867_1.xDOI Listing
July 2008

Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.

Circulation 2008 Apr 7;117(15):1991-6. Epub 2008 Apr 7.

Department of Cardiology, King's College London School of Medicine, 125 Coldharbour Ln, London SE5 9NU, United Kingdom.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.744540DOI Listing
April 2008

Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice.

Circ Res 2008 Feb 15;102(2):242-9. Epub 2007 Nov 15.

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, United Kingdom.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.164798DOI Listing
February 2008

Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling.

Cardiovasc Res 2008 Jan 18;77(2):256-64. Epub 2007 Sep 18.

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1093/cvr/cvm012DOI Listing
January 2008

Association of atrial nicotinamide adenine dinucleotide phosphate oxidase activity with the development of atrial fibrillation after cardiac surgery.

J Am Coll Cardiol 2008 Jan;51(1):68-74

University Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2007.07.085DOI Listing
January 2008

Cardiomyocytes as effectors of nitric oxide signalling.

Cardiovasc Res 2007 Jul 10;75(2):315-26. Epub 2007 May 10.

Department of Cardiology, Cardiovascular Division, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.cardiores.2007.04.031DOI Listing
July 2007

The emerging role of neuronal nitric oxide synthase in the regulation of myocardial function.

Authors:
Barbara Casadei

Exp Physiol 2006 Nov 21;91(6):943-55. Epub 2006 Sep 21.

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.

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http://doi.wiley.com/10.1113/expphysiol.2006.035493
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http://dx.doi.org/10.1113/expphysiol.2006.035493DOI Listing
November 2006

Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation.

Cardiovasc Res 2006 Apr 20;70(1):97-106. Epub 2006 Mar 20.

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1016/j.cardiores.2006.02.002DOI Listing
April 2006

nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction.

Circulation 2005 Dec;112(24):3729-37

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.539437DOI Listing
December 2005

Differentiation of athlete's heart from pathological forms of cardiac hypertrophy by means of geometric indices derived from cardiovascular magnetic resonance.

J Cardiovasc Magn Reson 2005 ;7(3):551-8

Department of Cardiovascular Medicine, University of Oxford, Centre for Clinical Magnetic Resonance Research, John Radcliffe Hospital, UK.

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http://dx.doi.org/10.1081/jcmr-200060631DOI Listing
October 2005

A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation.

Circ Res 2005 Sep 25;97(7):629-36. Epub 2005 Aug 25.

University Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1161/01.RES.0000183735.09871.61DOI Listing
September 2005

Is there a strong rationale for deferring elective surgery in patients with poorly controlled hypertension?

J Hypertens 2005 Jan;23(1):19-22

University Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK.

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January 2005

Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?

Philos Trans R Soc Lond B Biol Sci 2004 Jun;359(1446):1021-44

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1098/rstb.2004.1477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693378PMC
June 2004

EPR quantification of vascular nitric oxide production in genetically modified mouse models.

Nitric Oxide 2004 May;10(3):156-61

Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1016/j.niox.2004.04.003DOI Listing
May 2004

Nitric-oxide-mediated regulation of cardiac contractility and stretch responses.

Prog Biophys Mol Biol 2003 May-Jul;82(1-3):67-80

John Radcliffe Hospital, University Department of Cardiovascular Medicine, Headley Way Headington, OX3 9DU, Oxford, UK.

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July 2003

Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes.

Circulation 2002 Jun;105(25):3011-6

University Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1161/01.cir.0000019516.31040.2dDOI Listing
June 2002

Baroreflex sensitivity: population values.

Acta Cardiol 2002 Feb;57(1):41-2

University of Oxford Dept. of Cardiovascular Medicine, John Radcliffe Hospital, United Kingdom.

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February 2002