Barbara Bigerna

PU.1 subcellular localization in acute myeloid leukaemia with mutated NPM1.

Authors:

Giulia Pianigiani Camilla Betti Barbara Bigerna Riccardo Rossi Lorenzo Brunetti

Br J Haematol 2020 01 25;188(1):184-187. Epub 2019 Nov 25.

Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

January 2020

Different operators and histologic techniques in the assessment of germinal center-like structures in primary Sjögren's syndrome minor salivary glands.

Authors:

Francesco Carubbi Alessia Alunno Paola Cipriani Gino Coletti Barbara Bigerna Mirko Manetti Paola Di Benedetto Onelia Bistoni Gianluca Cipolloni Vasiliki Liakouli Piero Ruscitti Elena Bartoloni Roberto Giacomelli Roberto Gerli

PLoS One 2019 25;14(1):e0211142. Epub 2019 Jan 25.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

October 2019

IDH1-R132 changes vary according to NPM1 and other mutations status in AML.

Authors:

Brunangelo Falini Orietta Spinelli Manja Meggendorfer Maria Paola Martelli Barbara Bigerna Stefano Ascani Harald Stein Alessandro Rambaldi Torsten Haferlach

Leukemia 2019 04 8;33(4):1043-1047. Epub 2019 Jan 8.

The Munich Leukemia Laboratory, Munich, Germany.

View Article and Find Full Text PDF

April 2019

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma.

Blood 2018 05 12;131(22):2454-2465. Epub 2018 Apr 12.

Institute of Hematology and Center for Hemato-Oncology Research, University and Hospital of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

May 2018

Human monocyte-derived dendritic cells exposed to hyperthermia show a distinct gene expression profile and selective upregulation of .

Authors:

Arcangelo Liso Stefano Castellani Francesca Massenzio Rosa Trotta Alessandra Pucciarini Barbara Bigerna Pasquale De Luca Pietro Zoppoli Filippo Castiglione Maria Concetta Palumbo Fabrizio Stracci Matteo Landriscina Giorgina Specchia Leon A Bach Massimo Conese Brunangelo Falini

Oncotarget 2017 Sep 1;8(37):60826-60840. Epub 2017 Jun 1.

Institute of Haematology, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

September 2017

BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity.

Authors:

Valentina Pettirossi Alessia Santi Elisa Imperi Guido Russo Alessandra Pucciarini Barbara Bigerna Gianluca Schiavoni Elisabetta Fortini Ariele Spanhol-Rosseto Paolo Sportoletti Roberta Mannucci Maria Paola Martelli Ludger Klein-Hitpass Brunangelo Falini Enrico Tiacci

Blood 2015 Feb 5;125(8):1207-16. Epub 2014 Dec 5.

Institute of Hematology, and.

View Article and Find Full Text PDF

February 2015

CD4(-)CD8(-) T-cells in primary Sjögren's syndrome: association with the extent of glandular involvement.

Authors:

Alessia Alunno Francesco Carubbi Onelia Bistoni Sara Caterbi Elena Bartoloni Barbara Bigerna Roberta Pacini Daniela Beghelli Paola Cipriani Roberto Giacomelli Roberto Gerli

J Autoimmun 2014 Jun 24;51:38-43. Epub 2014 Jan 24.

Rheumatology Unit, Department of Medicine, University of Perugia, Via Enrico Dal Pozzo, s.n.c., Perugia I-06126, Italy. Electronic address:

View Article and Find Full Text PDF

June 2014

IL-17-producing CD4-CD8- T cells are expanded in the peripheral blood, infiltrate salivary glands and are resistant to corticosteroids in patients with primary Sjogren's syndrome.

Authors:

Alessia Alunno Onelia Bistoni Elena Bartoloni Sara Caterbi Barbara Bigerna Alessia Tabarrini Roberta Mannucci Brunangelo Falini Roberto Gerli

Ann Rheum Dis 2013 Feb 17;72(2):286-92. Epub 2012 Aug 17.

Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Via Enrico Dal Pozzo, Perugia I-06122, Italy.

View Article and Find Full Text PDF

February 2013

IRTA1 is selectively expressed in nodal and extranodal marginal zone lymphomas.

Authors:

Brunangelo Falini Claudio Agostinelli Barbara Bigerna Alessandra Pucciarini Roberta Pacini Alessia Tabarrini Flavio Falcinelli Milena Piccioli Marco Paulli Marcello Gambacorta Maurilio Ponzoni Enrico Tiacci Stefano Ascani Maria Paola Martelli Riccardo Dalla Favera Harald Stein Stefano A Pileri

Histopathology 2012 Nov 20;61(5):930-41. Epub 2012 Jun 20.

Institute of Haematology, University of Perugia, Ospedale S Maria della Misericordia, Perugia, Italy.

View Article and Find Full Text PDF

November 2012

Absence of BRAF-V600E in the human cell lines BONNA-12, ESKOL, HAIR-M, and HC-1 questions their origin from hairy cell leukemia.

Authors:

Enrico Tiacci Alessandra Pucciarini Barbara Bigerna Valentina Pettirossi Francesca Strozzini Maria Paola Martelli Alessia Tabarrini Hans G Drexler Brunangelo Falini

Blood 2012 May;119(22):5332-3

View Article and Find Full Text PDF

May 2012

BRAF mutations in hairy-cell leukemia.

N Engl J Med 2011 Jun 11;364(24):2305-15. Epub 2011 Jun 11.

Institute of Hematology, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

June 2011

Cytoplasmic mutated nucleophosmin is stable in primary leukemic cells and in a xenotransplant model of NPMc+ acute myeloid leukemia in SCID mice.

Authors:

Brunangelo Falini Maria Paola Martelli Cristina Mecucci Arcangelo Liso Niccolò Bolli Barbara Bigerna Alessandra Pucciarini Stefano Pileri Giovanna Meloni Massimo F Martelli Torsten Haferlach Susanne Schnittger

Haematologica 2008 May 26;93(5):775-9. Epub 2008 Mar 26.

Institute of Hematology, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

May 2008

Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutants.

Authors:

Niccolò Bolli Ildo Nicoletti M Felicetta De Marco Barbara Bigerna Alessandra Pucciarini Roberta Mannucci Maria Paola Martelli Arcangelo Liso Cristina Mecucci Francesco Fabbiano Massimo F Martelli Beric R Henderson Brunangelo Falini

Cancer Res 2007 Jul;67(13):6230-7

Section of Hematology and Immunology, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

July 2007

Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification.

Blood 2006 Dec 22;108(13):4146-55. Epub 2006 Aug 22.

Institute of Hematology, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

December 2006

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

Blood 2006 Jun 2;107(11):4514-23. Epub 2006 Feb 2.

Institute of Hematology, University of Perugia, 06122 Perugia, Italy.

View Article and Find Full Text PDF

June 2006

Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance.

Authors:

Myriam Alcalay Enrico Tiacci Roberta Bergomas Barbara Bigerna Elisa Venturini Simone P Minardi Natalia Meani Daniela Diverio Loris Bernard Laura Tizzoni Sara Volorio Lucilla Luzi Emanuela Colombo Francesco Lo Coco Cristina Mecucci Brunangelo Falini Pier Giuseppe Pelicci

Blood 2005 Aug 14;106(3):899-902. Epub 2005 Apr 14.

IFOM-IEO Campus, Via Adamello 16, 20139, Milan, Italy.

View Article and Find Full Text PDF

August 2005

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.

N Engl J Med 2005 Jan;352(3):254-66

Institute of Hematology, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

January 2005

Tumor protein D52 (TPD52): a novel B-cell/plasma-cell molecule with unique expression pattern and Ca(2+)-dependent association with annexin VI.

Blood 2005 Apr 2;105(7):2812-20. Epub 2004 Dec 2.

Section of Physiopathology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

View Article and Find Full Text PDF

April 2005

Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT).

Authors:

Brunangelo Falini Enrico Tiacci Alessandra Pucciarini Barbara Bigerna Julia Kurth Georgia Hatzivassiliou Sara Droetto Barbara Verducci Galletti Marcello Gambacorta Attilio Orazi Laura Pasqualucci Ira Miller Ralf Kuppers Riccardo Dalla-Favera Giorgio Cattoretti

Blood 2003 Nov 24;102(10):3684-92. Epub 2003 Jul 24.

Institute of Hematology, University of Perugia, 06122 Perugia, Italy.

View Article and Find Full Text PDF

November 2003

Publications by authors named "Barbara Bigerna"

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors:

Authors: