Barbara A Malynn

Barbara A Malynn

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Barbara A Malynn

Barbara A Malynn

Publications by authors named "Barbara A Malynn"

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A20: A multifunctional tool for regulating immunity and preventing disease.

Cell Immunol 2019 Jun 5;340:103914. Epub 2019 Apr 5.

Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2019.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584049PMC
June 2019

OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination.

J Biol Chem 2018 11 3;293(47):18285-18295. Epub 2018 Oct 3.

From the Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2185 and

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http://dx.doi.org/10.1074/jbc.RA118.004677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254341PMC
November 2018

Ubiquitin-Modifying Enzymes and Regulation of the Inflammasome.

J Mol Biol 2017 11 13;429(22):3471-3485. Epub 2017 Oct 13.

Department of Medicine, University of California, San Francisco, San Francisco, CA 94143-0358, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675782PMC
November 2017

The Ubiquitin Binding Protein TAX1BP1 Mediates Autophagasome Induction and the Metabolic Transition of Activated T Cells.

Immunity 2017 03 14;46(3):405-420. Epub 2017 Mar 14.

Department of Medicine, University of California, San Francisco, San Francisco, CA 94143-0358, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400745PMC
March 2017

A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity.

Immunity 2015 Jan;42(1):55-67

Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.12.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302274PMC
January 2015

A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.

PLoS One 2013 6;8(5):e62223. Epub 2013 May 6.

Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062223PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645994PMC
December 2013

A20: linking a complex regulator of ubiquitylation to immunity and human disease.

Nat Rev Immunol 2012 Nov 12;12(11):774-85. Epub 2012 Oct 12.

Department of Medicine, University of California, San Francisco, California 94143-0451, USA.

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http://www.nature.com/articles/nri3313
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http://dx.doi.org/10.1038/nri3313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582397PMC
November 2012

Ubiquitin makes its mark on immune regulation.

Immunity 2010 Dec;33(6):843-52

Department of Medicine, Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143-0451, USA.

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http://dx.doi.org/10.1016/j.immuni.2010.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030984PMC
December 2010

Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets.

Immunity 2009 Nov 12;31(5):811-22. Epub 2009 Nov 12.

Department of Medicine, University of California, San Francisco, San Francisco, CA 94143-0451, USA.

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http://dx.doi.org/10.1016/j.immuni.2009.09.017DOI Listing
November 2009

A20 takes on tumors: tumor suppression by an ubiquitin-editing enzyme.

J Exp Med 2009 May 20;206(5):977-80. Epub 2009 Apr 20.

Program in Biomedical Sciences, Program in Biological Sciences, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1084/jem.20090765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715039PMC
May 2009

ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development.

Nature 2009 Feb 7;457(7231):906-9. Epub 2008 Dec 7.

Department of Medicine, University of California at San Francisco, 513 Parnassus Avenue, S-1057, San Francisco, California 94143-0451, USA.

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http://dx.doi.org/10.1038/nature07575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642523PMC
February 2009

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals.

Immunity 2008 Mar;28(3):381-90

UCSF Colitis Center, Gastroenterology Division, Department of Medicine, Program in Biomedical Sciences, University of California at San Francisco, San Francisco, CA 94143-0538, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130800073
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http://dx.doi.org/10.1016/j.immuni.2008.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606373PMC
March 2008

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

J Exp Med 2008 Feb 11;205(2):451-64. Epub 2008 Feb 11.

Gastrointestinal Division, Department of Medicine, Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1084/jem.20071108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271029PMC
February 2008

Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease.

Proc Natl Acad Sci U S A 2005 Aug 29;102(32):11272-7. Epub 2005 Jul 29.

Howard Hughes Medical Institute, Dana-Farber Cancer Institute, and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0504783102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183578PMC
August 2005

Truncated immunoglobulin Dmu causes incomplete developmental progression of RAG-deficient pro-B cells.

Mol Immunol 2002 Jan;38(7):547-56

The Center for Blood Research, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/s0161-5890(01)00085-2DOI Listing
January 2002