Publications by authors named "Balazs Dome"

100Publications

[Therapeutic possibilities in KRAS-mutant lung adenocarcinoma].

Magy Onkol 2020 Sep 6;64(3):231-244. Epub 2020 Aug 6.

Mellkassebészeti Osztály, Országos Onkológiai Intézet, Budapest, Hungary.

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September 2020

Longitudinal analysis of complete blood count parameters in advanced-stage lung cancer patients.

Thorac Cancer 2020 11 17;11(11):3193-3204. Epub 2020 Sep 17.

1st Department of Pulmonology, National Koranyi Institute of Pulmonology, Budapest, Hungary.

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November 2020

DNA Polymerase Alpha Subunit B Is a Binding Protein for Erlotinib Resistance in Non-Small Cell Lung Cancer.

Cancers (Basel) 2020 Sep 13;12(9). Epub 2020 Sep 13.

Chemical Genomics Global Research Lab, Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Korea.

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September 2020

Current therapy of KRAS-mutant lung cancer.

Cancer Metastasis Rev 2020 Dec;39(4):1159-1177

Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University, Rath Gyorgy u. 7-9, Budapest, 1122, Hungary.

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December 2020

Proteomic analysis enables distinction of early- versus advanced-stage lung adenocarcinomas.

Clin Transl Med 2020 Jun 14;10(2):e106. Epub 2020 Jun 14.

Clinical Protein Science and Imaging, Biomedical Center, Department of Biomedical Engineering, Lund University, Lund, Sweden.

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June 2020

Profiling the Protein Targets of Unmodified Bio-Active Molecules with Drug Affinity Responsive Target Stability and Liquid Chromatography/Tandem Mass Spectrometry.

Proteomics 2020 05 5;20(9):e1900325. Epub 2020 Feb 5.

Chemical Genomics Global Research Lab, Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul, 03722, Korea.

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May 2020

Follistatin impacts Tumor Angiogenesis and Outcome in Thymic Epithelial Tumors.

Sci Rep 2019 11 22;9(1):17359. Epub 2019 Nov 22.

Christian Doppler Laboratory for Diagnosis and Regeneration of Cardiac and Thoracic Diseases, Medical University Vienna, Vienna, Austria.

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November 2019

JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression.

Int J Cancer 2019 12 10;145(12):3376-3388. Epub 2019 Sep 10.

Department of Physiology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, Vienna, Austria.

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December 2019

PD-L1 Expression of Lung Cancer Cells, Unlike Infiltrating Immune Cells, Is Stable and Unaffected by Therapy During Brain Metastasis.

Clin Lung Cancer 2019 09 15;20(5):363-369.e2. Epub 2019 May 15.

1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary; SE-NAP Brain Metastasis Research Group, 2nd Department of Pathology, Semmelweis University, Budapest, Hungary. Electronic address:

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September 2019

Tumor necrosis correlates with PD-L1 and PD-1 expression in lung adenocarcinoma.

Acta Oncol 2019 Aug 19;58(8):1087-1094. Epub 2019 Apr 19.

b 2nd Department of Pathology, MTA-SE NAP Brain Metastasis Research Group Hungarian Academy of Sciences , Semmelweis University , Budapest , Hungary.

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August 2019

The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma.

J Mol Med (Berl) 2019 02 11;97(2):231-242. Epub 2018 Dec 11.

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

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February 2019

Role of (myo)fibroblasts in the development of vascular and connective tissue structure of the C38 colorectal cancer in mice.

Cancer Commun (Lond) 2018 07 5;38(1):46. Epub 2018 Jul 5.

First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Üllői út 26, 1085, Hungary.

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July 2018

Chemotherapy treatment is associated with altered PD-L1 expression in lung cancer patients.

J Cancer Res Clin Oncol 2018 Jul 19;144(7):1219-1226. Epub 2018 Apr 19.

VI. Department of Pulmonology, National Korányi Institute of Pulmonology, Pihenő u. 1, Budapest, 1121, Hungary.

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July 2018

Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis.

Basic Clin Pharmacol Toxicol 2017 Aug 21. Epub 2017 Aug 21.

Department of Tumor Biology, National Korányi Institute of Pulmonology - Semmelweis University, Budapest, Hungary.

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August 2017

BARD1 serum autoantibodies for the detection of lung cancer.

PLoS One 2017 7;12(8):e0182356. Epub 2017 Aug 7.

Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics, Medical Genetics and Laboratories, Geneva University Hospitals, Geneva, Switzerland.

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October 2017

Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis.

Basic Clin Pharmacol Toxicol 2018 Jan 24;122(1):126-132. Epub 2017 Aug 24.

Department of Tumor Biology, National Korányi Institute of Pulmonology - Semmelweis University, Budapest, Hungary.

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January 2018

Trimodality therapy for Pancoast tumors: T4 is not a contraindication to radical surgery.

J Surg Oncol 2017 Aug 13;116(2):227-235. Epub 2017 Apr 13.

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria.

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August 2017

Evaluating the significance of density, localization, and PD-1/PD-L1 immunopositivity of mononuclear cells in the clinical course of lung adenocarcinoma patients with brain metastasis.

Neuro Oncol 2017 Aug;19(8):1058-1067

First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary; MTA-SE NAP, Brain Metastasis Research Group, Hungarian Academy of Sciences, Second Department of Pathology, Semmelweis University, Budapest, Hungary; Department of Pulmonology, Semmelweis University, Budapest, Hungary; Department of Physics of Complex Systems, Eötvös Loránd University, Budapest, Hungary; Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary; Department of Neurooncology, National Institute of Clinical Neurosciences, Budapest, Hungary; Department of Radiology, National Institute of Clinical Neurosciences, Budapest, Hungary; Sixth Department of Pulmonology, National Korányi Institute of Pulmonology, Budapest, Hungary; Hungarian Academy of Sciences-Semmelweis University, Molecular Oncology Research Unit, Budapest, Hungary; Department of Tumor Biology, National Korányi Institute of Pulmonology-Semmelweis University, Budapest, Hungary; Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University, Budapest, Hungary; Division of Thoracic Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria; Children's Hospital Informatics Program at the Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Harvard Medical School, Boston, Massachusetts, USA; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark; CRUK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, UK; Francis Crick Institute, London, UK.

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August 2017

Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors.

Theranostics 2017 1;7(2):400-412. Epub 2017 Jan 1.

National Korányi Institute of Pulmonology, Budapest, Hungary;; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria;; Department of Thoracic Surgery, Semmelweis University and National Institute of Oncology, Budapest, Hungary;; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.

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October 2017

A comparison of sample preparation strategies for biological tissues and subsequent trace element analysis using LA-ICP-MS.

Anal Bioanal Chem 2017 Mar 14;409(7):1805-1814. Epub 2016 Dec 14.

Institute of Chemical Technologies and Analytics, TU Wien, Getreidemarkt 9/164-IAC, 1060, Vienna, Austria.

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March 2017

Maternal bonding styles in smokers and non-smokers: a comparative study.

Ann Gen Psychiatry 2016 11;15:32. Epub 2016 Nov 11.

Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary.

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November 2016

Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo.

Surgery 2017 03 21;161(3):735-746. Epub 2016 Oct 21.

Department of Surgery, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria. Electronic address:

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March 2017

Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma - A multi-institutional study.

Eur J Cancer 2016 08 8;63:64-73. Epub 2016 Jun 8.

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria; MTA-SE Molecular Oncology Research Group, Hungarian Academy of Sciences, Budapest, Hungary. Electronic address:

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August 2016

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.

Oncotarget 2016 Mar;7(12):13388-99

Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.

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March 2016

Mechanisms of vascularization in murine models of primary and metastatic tumor growth.

Chin J Cancer 2016 Feb 12;35:19. Epub 2016 Feb 12.

1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.

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February 2016

Differences in the Epidemiology of Rare EGFR Mutations in Different Populations.

J Thorac Oncol 2016 Jan;11(1):e19-20

Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria; 2nd Department of Pathology, Semmelweis University, Budapest, Hungary; Molecular Oncology Research Group, Hungarian Academy of Sciences-Semmelweis University, Budapest, Hungary.

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January 2016

From Bench to Bedside: Attempt to Evaluate Repositioning of Drugs in the Treatment of Metastatic Small Cell Lung Cancer (SCLC).

PLoS One 2016 6;11(1):e0144797. Epub 2016 Jan 6.

Western Regional Medical Center, Cancer Treatment Centers of America, Goodyear, Arizona, United States of America.

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July 2016

[Role of tumour cell invasion/migration in the vascularisation of experimental lung metastases].

Magy Onkol 2015 Dec 10;59(4):319-23. Epub 2015 Oct 10.

Molekuláris Onkológia Kutatócsoport, MTA-SE, Budapest, Hungary.

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December 2015

Heme oxygenase-1 in macrophages controls prostate cancer progression.

Oncotarget 2015 Oct;6(32):33675-88

Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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October 2015

Reply to Rare Versus Artifactual EGFR Mutations.

J Thorac Oncol 2015 Aug;10(8):e80-1

National Koranyi Institute of Pulmonology, Budapest, Hungary, Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria, Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University, Budapest, Hungary National Koranyi Institute of Pulmonology, Budapest, Hungary National Koranyi Institute of Pulmonology, Budapest, Hungary, Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University, Budapest, Hungary National Koranyi Institute of Pulmonology, Budapest, Hungary, Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria, Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University, Budapest, Hungary Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria, 2nd Department of Pathology, Semmelweis University, Budapest, Hungary, Molecular Oncology Research Group, Hungarian Academy of Sciences-Semmelweis University, Budapest, Hungary.

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August 2015

Drug compound characterization by mass spectrometry imaging in cancer tissue.

Arch Pharm Res 2015 Sep 23;38(9):1718-27. Epub 2015 Jul 23.

Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, BMC D13, Lund, Sweden.

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September 2015

A protein deep sequencing evaluation of metastatic melanoma tissues.

PLoS One 2015 13;10(4):e0123661. Epub 2015 Apr 13.

Centre of Excellence in Biological and Medical Mass Spectrometry "CEBMMS", Biomedical Centre D13, Lund University, Lund, Sweden; Clinical Protein Science & Imaging, Biomedical Centre, Dept. of Biomedical Engineering, Lund University, Lund, Sweden; First Dept. of Surgery, Tokyo Medical University, Tokyo, Japan.

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January 2016

Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases.

PLoS One 2015 20;10(3):e0120724. Epub 2015 Mar 20.

Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, Medical University of Vienna, Vienna, Austria.

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February 2016

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

J Thorac Oncol 2015 May;10(5):738-746

Translational Thoracic Oncology Laboratory, Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria; Molecular Oncology Research Group, Hungarian Academy of Sciences-Semmelweis University, Budapest, Hungary. Electronic address:

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May 2015

Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells.

PLoS One 2015 3;10(2):e0117021. Epub 2015 Feb 3.

Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria; MTA-SE Molecular Oncology Research Group, Hungarian Academy of Sciences, Budapest, Hungary.

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January 2016

The possible role of maternal bonding style and CHRNB2 gene polymorphisms in nicotine dependence and related depressive phenotype.

Prog Neuropsychopharmacol Biol Psychiatry 2015 Jun 29;59:84-90. Epub 2015 Jan 29.

Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary. Electronic address:

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June 2015

Localization of sunitinib in in vivo animal and in vitro experimental models by MALDI mass spectrometry imaging.

Anal Bioanal Chem 2015 Mar 26;407(8):2245-53. Epub 2014 Nov 26.

Clinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, Biomedical Center D13, 221 84, Lund, Sweden.

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March 2015

Apelin promotes lymphangiogenesis and lymph node metastasis.

Oncotarget 2014 Jun;5(12):4426-37

Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria; Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary; Thoracic Surgery, National Institute of Oncology and Semmelweis University, Budapest, Hungary.

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June 2014

Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy.

Eur J Cancer 2014 Jul 22;50(10):1819-1828. Epub 2014 Apr 22.

Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary; Division of Thoracic Surgery, Medical University of Vienna, Austria; Department of Thoracic Surgery, National Institute of Oncology-Semmelweis University, Budapest, Hungary. Electronic address:

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July 2014

Massive withdrawal symptoms and affective vulnerability are associated with variants of the CHRNA4 gene in a subgroup of smokers.

PLoS One 2014 30;9(1):e87141. Epub 2014 Jan 30.

Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary ; Department of Thoracic Surgery, National Institute of Oncology, Budapest, Hungary ; Translational Thoracic Oncology Lab, Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.

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September 2014

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma.

PLoS One 2013 14;8(10):e77459. Epub 2013 Oct 14.

Department of Tumor Biology, National Koranyi Institute of Pulmonology, Budapest, Hungary ; Division of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.

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June 2014

Experimental models to study drug distributions in tissue using MALDI mass spectrometry imaging.

J Proteome Res 2013 Dec 6;12(12):5626-33. Epub 2013 Nov 6.

Clinical Protein Science & Imaging, Biomedical Center, Department of Measurement Technology and Industrial Electrical Engineering, Lund University , BMC C13, SE-221 84 Lund, Sweden.

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December 2013

Encephalitis and GABAB receptor antibodies: novel findings in a new case series of 20 patients.

Neurology 2013 Oct 25;81(17):1500-6. Epub 2013 Sep 25.

From the Service of Neurology (R.H., M.T., L.S., A.S., F.G.), Hospital Clínic, Universitat de Barcelona and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Institute of Neurology (R.H.), Medical University of Vienna, Austria; Department of Neurology (M.T.), Erasmus Medical Center, Rotterdam, the Netherlands; Department of Tumor Biology (B.D., A.R., B.H., M.A.H., V.L.), National Koranyi Institute of TB and Pulmonology, Budapest, Hungary; Department of Thoracic Surgery (B.D., A.R., B.H., M.A.H., V.L., H.J.A.), Medical University of Vienna, Austria; 2nd Department of Pathology (B.H.), Semmelweis University, Budapest, Hungary; Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration (H.J.A.), Vienna, Austria; Department of Neurology (L.H.), Charité University Medicine Berlin, Germany; Servicio Neurología (S.B.), Hospital de Cruces, Barakaldo; Servicio Neurología (A.d.F.), Hospital Ramón y Cajal, Madrid; Institució Catalana de Recerca i Estudis Avançats (ICREA) (J.D.), IDIBAPS, Hospital Clínic, Barcelona, Spain; and Department of Neurology (J.D.), University of Pennsylvania, Philadelphia.

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October 2013

[Nintedanib (BIBF 1120) in the treatment of solid cancers: an overview of biological and clinical aspects].

Magy Onkol 2012 Sep 1;56(3):199-208. Epub 2012 Aug 1.

Tumorbiológiai Osztály, Országos Korányi TBC és Pulmonológiai Intézet, Budapest, Hungary.

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September 2012