Baktybek Kojonazarov

Baktybek Kojonazarov

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Baktybek Kojonazarov

Baktybek Kojonazarov

Publications by authors named "Baktybek Kojonazarov"

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Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung.

Am J Physiol Lung Cell Mol Physiol 2020 Apr 18;318(4):L831-L843. Epub 2020 Mar 18.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1152/ajplung.00295.2019DOI Listing
April 2020

Severe Emphysema in the SU5416/Hypoxia Rat Model of Pulmonary Hypertension.

Am J Respir Crit Care Med 2019 08;200(4):515-518

1Justus Liebig University of Giessen, member of the German Center for Lung ResearchGiessen, Germanyand.

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http://dx.doi.org/10.1164/rccm.201902-0390LEDOI Listing
August 2019

Evidence for the Fucoidan/P-Selectin Axis as a Therapeutic Target in Hypoxia-induced Pulmonary Hypertension.

Am J Respir Crit Care Med 2019 06;199(11):1407-1420

1 Universities of Giessen and Marburg Lung Center, Department of Internal Medicine, Member of the German Center for Lung Research, Justus Liebig University Giessen, Giessen, Germany; and.

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http://dx.doi.org/10.1164/rccm.201806-1170OCDOI Listing
June 2019

Riociguat for treatment of pulmonary hypertension in COPD: a translational study.

Eur Respir J 2019 Jun 27;53(6). Epub 2019 Jun 27.

Excellence Cluster Cardiopulmonary System, University of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University, Giessen, Germany

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http://dx.doi.org/10.1183/13993003.02445-2018DOI Listing
June 2019

Nitric Oxide Synthase 2 Induction Promotes Right Ventricular Fibrosis.

Am J Respir Cell Mol Biol 2019 03;60(3):346-356

1 Universities of Giessen and Marburg Lung Center, Giessen, Germany.

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http://dx.doi.org/10.1165/rcmb.2018-0069OCDOI Listing
March 2019

Evaluating Systolic and Diastolic Cardiac Function in Rodents Using Microscopic Computed Tomography.

Circ Cardiovasc Imaging 2018 12;11(12):e007653

German Center for Lung Research (DZL), Justus-Liebig University of Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany (B.K., J.W., M.K., H.A.G., F.G., N.W., W.S., R.T.S.).

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http://dx.doi.org/10.1161/CIRCIMAGING.118.007653DOI Listing
December 2018

Nintedanib in Severe Pulmonary Arterial Hypertension.

Am J Respir Crit Care Med 2018 09;198(6):808-810

1 Universities of Giessen and Marburg Lung Centre, member of the German Centre for Lung Research Giessen, Germany.

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http://dx.doi.org/10.1164/rccm.201801-0195LEDOI Listing
September 2018

Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension.

BMC Pulm Med 2018 Mar 2;18(1):41. Epub 2018 Mar 2.

Universities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Aulweg 130, 35392, Giessen, Germany.

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http://dx.doi.org/10.1186/s12890-018-0604-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833097PMC
March 2018

ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension.

Am J Respir Crit Care Med 2018 02;197(3):373-385

2 Universities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Giessen, Germany; and.

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http://dx.doi.org/10.1164/rccm.201703-0502OCDOI Listing
February 2018

p38 MAPK Inhibition Improves Heart Function in Pressure-Loaded Right Ventricular Hypertrophy.

Am J Respir Cell Mol Biol 2017 11;57(5):603-614

1 Universities of Giessen and Marburg Lung Center, Excellence Cluster Cardio-Pulmonary System, Member of the German Center for Lung Research, Giessen, Germany.

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http://dx.doi.org/10.1165/rcmb.2016-0374OCDOI Listing
November 2017

Maintained right ventricular pressure overload induces ventricular-arterial decoupling in mice.

Exp Physiol 2017 02;102(2):180-189

Universities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Giessen, Germany.

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http://dx.doi.org/10.1113/EP085963DOI Listing
February 2017

Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension.

Eur Respir J 2016 10 28;48(4):1137-1149. Epub 2016 Jul 28.

Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research (DZL), Giessen, Germany

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http://dx.doi.org/10.1183/13993003.00773-2015DOI Listing
October 2016

miR-223-IGF-IR signalling in hypoxia- and load-induced right-ventricular failure: a novel therapeutic approach.

Cardiovasc Res 2016 08 24;111(3):184-93. Epub 2016 Mar 24.

Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, Frankfurt am Main, and German Center of Cardiovascular Research (DZHK), Partner site RheinMain, Frankfurt am Main, Germany

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http://dx.doi.org/10.1093/cvr/cvw065DOI Listing
August 2016

Endogenous Asymmetric Dimethylarginine Pathway in High Altitude Adapted Yaks.

Biomed Res Int 2015 26;2015:196904. Epub 2015 Aug 26.

Laboratory of Molecular and Cell Biology, Institute of Molecular Biology and Medicine, 720040 Bishkek, Kyrgyzstan.

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http://dx.doi.org/10.1155/2015/196904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563057PMC
June 2016

Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice.

Basic Res Cardiol 2016 Mar 24;111(2):22. Epub 2016 Feb 24.

Physiologisches Institut der Universität Würzburg, Röntgenring 9, 97070, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00395-016-0541-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766231PMC
March 2016

Blunted activation of Rho-kinase in yak pulmonary circulation.

Biomed Res Int 2015 14;2015:720250. Epub 2015 Jan 14.

Laboratory of Molecular and Cell Biology, Institute of Molecular Biology and Medicine, 720040 Bishkek, Kyrgyzstan.

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http://dx.doi.org/10.1155/2015/720250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310305PMC
October 2015

5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure.

Biomed Res Int 2015 1;2015:438403. Epub 2015 Feb 1.

Universities of Giessen and Marburg Lung Centre (UGMLC), Aulweg 130, 35392 Giessen, Germany ; German Center for Lung Research (DZL), 35392 Giessen, Germany.

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http://dx.doi.org/10.1155/2015/438403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312574PMC
October 2015

The F-BAR Protein NOSTRIN Dictates the Localization of the Muscarinic M3 Receptor and Regulates Cardiovascular Function.

Circ Res 2015 Aug 13;117(5):460-9. Epub 2015 Jul 13.

From the Institute for Biochemistry II, Goethe-University Frankfurt Medical School, Frankfurt/Main, Germany (I.K., M.M., A.E., T.H., M.H., S.O.); Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Giessen, Germany (B.K., R.T.S.); and Institute for Vascular Signalling, Goethe-University Frankfurt, Frankfurt/Main, Germany (V.R., K.K., I.F.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306187DOI Listing
August 2015

α1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders.

Circ Cardiovasc Genet 2014 Dec 4;7(6):920-9. Epub 2014 Nov 4.

From the Department of Medicine, Imperial College London, London, United Kingdom (M.R.W., J.W., C.J.R., S.R.); National Academy of Sciences of Kyrgyz Republic, Bishkek, Kyrgyz Republic (A.A.A.); Physiological Genomics and Medicine Group, MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom (J.V., T.J.A.); NIHR BRC Clinical Genome Informatics Facility, Imperial College London, London, United Kingdom (D.K., S.G.B., M.M.); Cardiology Research, Bayer Pharma AG, Wuppertal, Germany (S.G., J.-P.S.); Department of Pharmacology, The School of Pharmacy, Martin-Luther-University, Halle, Germany (J.-P.S.); Department of Pulmonary Pharmacotherapy, University of Giessen and Marburg Lung Center, Giessen, Germany (B.K.); Department of Medicine, University of Cambridge, Cambridge, United Kingdom (N.W.M.); Department of Pharmacology, Toxicology, and Clinical Pharmacy, University of Braunschweig-Center of Pharmaceutical Engineering, Braunschweig, Germany (I.N., S.B.); and Department of Chemistry, The Scripps Research Institute, La Jolla, CA (N.B.S., M.A.M.).

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000763DOI Listing
December 2014

Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension.

Nat Med 2014 Nov 26;20(11):1289-300. Epub 2014 Oct 26.

1] Max-Planck-Institute for Heart and Lung Research, Department of Lung Development and Remodeling, member of the German Center for Lung Research (DZL), Bad Nauheim, Germany. [2] Department of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), member of the DZL, Justus-Liebig University, Giessen, Germany.

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http://basicmed.med.ncku.edu.tw/public/project/1464-14258576
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http://www.nature.com/doifinder/10.1038/nm.3695
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http://dx.doi.org/10.1038/nm.3695DOI Listing
November 2014

Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling.

Circulation 2014 Apr 27;129(14):1510-23. Epub 2014 Jan 27.

Excellence Cluster Cardio-Pulmonary System, Universities of Giessen and Marburg Lung Center, Member of the German Lung Center, Justus-Liebig-University Giessen, Giessen, Germany (F.C.W., C.K., A.P., A.S., B.K., J.W., M.R., H.A.G., F.G., W.S., R.T.S., N.W., G.K.); Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL (K.M.R.); Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan (K.I., K.N.); University of Hamburg, Pharmaceutical and Medicinal Chemistry, Hamburg, Germany (W.M., C.W.); Department of Cardiothoracic Surgery, University Hospital of Vienna, Vienna, Austria (W.K., P.J.); Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany (W.S.); and Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria (G.K.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.006402DOI Listing
April 2014

Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling.

Int J Cardiol 2013 Sep 31;167(6):2630-7. Epub 2012 Jul 31.

Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2012.06.129DOI Listing
September 2013

The role of cGMP in the physiological and molecular responses of the right ventricle to pressure overload.

Exp Physiol 2013 Aug;98(8):1274-8

Pulmonary Pharmacotherapy, Universities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of German Center for Lung Research, Giessen, Germany.

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http://dx.doi.org/10.1113/expphysiol.2012.069138DOI Listing
August 2013

Bosentan reduces pulmonary artery pressure in high altitude residents.

High Alt Med Biol 2012 Sep;13(3):217-23

Institute of Molecular Biology and Medicine, Bishkek, Kyrgyzstan.

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http://dx.doi.org/10.1089/ham.2011.1107DOI Listing
September 2012

Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension.

Am J Respir Crit Care Med 2012 Feb 8;185(4):409-19. Epub 2011 Dec 8.

Max-Planck-Institute for Heart and Lung Research, Department of Lung Development and Remodeling, Bad Nauheim, Germany.

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http://dx.doi.org/10.1164/rccm.201106-1093OCDOI Listing
February 2012

Dobutamine potentiates arterial chemoreflex sensitivity in healthy normal humans.

Am J Physiol Heart Circ Physiol 2003 Sep 15;285(3):H1356-61. Epub 2003 May 15.

Department of Cardiology, Erasme Hospital, 808 Lennik Road, 1070 Brussels, Belgium.

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http://dx.doi.org/10.1152/ajpheart.01126.2002DOI Listing
September 2003