Bakela Nare

Bakela Nare

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Bakela Nare

Bakela Nare

Publications by authors named "Bakela Nare"

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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Targeting Lysine Deacetylases (KDACs) in Parasites.

PLoS Negl Trop Dis 2015 24;9(9):e0004026. Epub 2015 Sep 24.

The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America; Departments of Genetics and of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581690PMC
March 2016

Novel pyrrolobenzoxaboroles: design, synthesis, and biological evaluation against Trypanosoma brucei.

Eur J Med Chem 2014 Jun 29;81:59-75. Epub 2014 Apr 29.

State Key Laboratory of Microbial Metabolism, and School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.04.079DOI Listing
June 2014

MK-4815, a potential new oral agent for treatment of malaria.

Antimicrob Agents Chemother 2012 May 6;56(5):2414-9. Epub 2012 Feb 6.

Merck Research Laboratories, Department of Infectious Disease, Rahway, New Jersey, USA.

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http://aac.asm.org/lookup/doi/10.1128/AAC.05326-11
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http://dx.doi.org/10.1128/AAC.05326-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346645PMC
May 2012

Chalcone-benzoxaborole hybrid molecules as potent antitrypanosomal agents.

J Med Chem 2012 Apr 14;55(7):3553-7. Epub 2012 Mar 14.

School of Pharmacy, Shanghai Jiao Tong University, 200240, Shanghai, China.

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http://dx.doi.org/10.1021/jm2012408DOI Listing
April 2012

State of the art in African trypanosome drug discovery.

Curr Top Med Chem 2011 ;11(10):1255-74

SCYNEXIS, Inc., Research Triangle Park, North Carolina 27709-2878, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101707PMC
http://dx.doi.org/10.2174/156802611795429167DOI Listing
August 2011

PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major.

Curr Genet 2009 Jun 25;55(3):287-99. Epub 2009 Apr 25.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s00294-009-0244-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759280PMC
June 2009

Inhibitors of casein kinase 1 block the growth of Leishmania major promastigotes in vitro.

Int J Parasitol 2006 Oct 20;36(12):1249-59. Epub 2006 Jul 20.

Department of Infectious Disease Research, Merck Research Laboratories, Merck and Co., Inc., P.O. Box 2000 Rahway, NJ 07065-0900, USA.

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http://dx.doi.org/10.1016/j.ijpara.2006.06.013DOI Listing
October 2006

Anticoccidial kinase inhibitors: identification of protein kinase targets secondary to cGMP-dependent protein kinase.

Mol Biochem Parasitol 2006 Sep 23;149(1):86-98. Epub 2006 May 23.

Department of Infectious Diseases, Merck & Co., P.O. Box 2000, R80Y-260 Rahway, NJ 07065-0900, USA.

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http://dx.doi.org/10.1016/j.molbiopara.2006.05.003DOI Listing
September 2006

Highly substituted terphenyls as inhibitors of parasite cGMP-dependent protein kinase activity.

J Nat Prod 2006 Apr;69(4):710-2

Natural Products Chemistry and Human and Animal Infectious Disease, Merck Research Laboratories, P.O. Box 2000, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1021/np0505418DOI Listing
April 2006

Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity.

J Nat Prod 2005 Apr;68(4):611-3

Natural Products Chemistry and Human and Animal Infectious Disease, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.

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http://dx.doi.org/10.1021/np049591nDOI Listing
April 2005

Toxoplasma gondii cyclic GMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase.

Eukaryot Cell 2002 Jun;1(3):317-28

Department of Human and Animal Infectious Disease Research, Merck Research Laboratories, Merck and Co., Inc., Rahway New Jersey 07065, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC118020PMC
http://dx.doi.org/10.1128/ec.1.3.317-328.2002DOI Listing
June 2002

Evaluation of a cyclic GMP-dependent protein kinase inhibitor in treatment of murine toxoplasmosis: gamma interferon is required for efficacy.

Antimicrob Agents Chemother 2002 Feb;46(2):300-7

Department of Human and Animal Infectious Disease Research, Merck Research Laboratories, Merck and Co., Inc., Rahway, New Jersey 07076, USA.

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http://aac.asm.org/content/46/2/300.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127074PMC
http://dx.doi.org/10.1128/aac.46.2.300-307.2002DOI Listing
February 2002