Baitang Ning

Baitang Ning

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Baitang Ning

Publications by authors named "Baitang Ning"

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MicroRNAs hsa-miR-495-3p and hsa-miR-486-5p suppress basal and rifampicin-induced expression of human sulfotransferase 2A1 (SULT2A1) by facilitating mRNA degradation.

Biochem Pharmacol 2019 Nov 22;169:113617. Epub 2019 Aug 22.

National Center for Toxicological Research (NCTR), U.S. Food and Drug Administration (FDA), 3900 NCTR Road, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.08.019DOI Listing
November 2019

Advances and challenges in studying noncoding RNA regulation of drug metabolism and development of RNA therapeutics.

Biochem Pharmacol 2019 Nov 10;169:113638. Epub 2019 Sep 10.

Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.113638DOI Listing
November 2019

Sequencing XMET genes to promote genotype-guided risk assessment and precision medicine.

Sci China Life Sci 2019 Jul 20;62(7):895-904. Epub 2019 May 20.

National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.

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http://dx.doi.org/10.1007/s11427-018-9479-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612563PMC
July 2019

QuaPra: Efficient transcript assembly and quantification using quadratic programming with Apriori algorithm.

Sci China Life Sci 2019 Jul 22;62(7):937-946. Epub 2019 May 22.

The Center for Bioinformatics and Computational Biology, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.

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http://dx.doi.org/10.1007/s11427-018-9433-3DOI Listing
July 2019

Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis.

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2019 15;37(3):180-214. Epub 2019 Jul 15.

a National Center for Toxicological Research (NCTR), U.S. Food and Drug Administration (FDA) , Jefferson , AR , USA.

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http://dx.doi.org/10.1080/10590501.2019.1639481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737535PMC
July 2019

Single-Cell RNA-Seq Technologies and Related Computational Data Analysis.

Front Genet 2019 5;10:317. Epub 2019 Apr 5.

Center for Bioinformatics and Computational Biology, and Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, China.

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http://dx.doi.org/10.3389/fgene.2019.00317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460256PMC
April 2019

The Development of a Database for Herbal and Dietary Supplement Induced Liver Toxicity.

Int J Mol Sci 2018 Sep 28;19(10). Epub 2018 Sep 28.

Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.3390/ijms19102955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213387PMC
September 2018

Application of genome analysis strategies in the clinical testing for pediatric diseases.

Pediatr Investig 2018 Jul;2(2):72-81

Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, MOE Key Laboratory of Major Diseases in Children, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

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http://dx.doi.org/10.1002/ped4.12044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089540PMC
July 2018

The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone.

Arch Toxicol 2018 06 3;92(6):1969-1981. Epub 2018 Apr 3.

Division of Biochemical Toxicology, HFT-110, National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), 3900 NCTR Road, Jefferson, AR, 72079, USA.

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http://dx.doi.org/10.1007/s00204-018-2196-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348481PMC
June 2018

DNA damage-induced apoptosis and mitogen-activated protein kinase pathway contribute to the toxicity of dronedarone in hepatic cells.

Environ Mol Mutagen 2018 05 5;59(4):278-289. Epub 2018 Feb 5.

Division of Biochemical Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, 72079.

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http://dx.doi.org/10.1002/em.22173DOI Listing
May 2018

The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p.

Biochem Pharmacol 2017 12 16;145:178-191. Epub 2017 Aug 16.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712447PMC
December 2017

Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells.

Toxicology 2017 12 5;392:11-21. Epub 2017 Oct 5.

Division of Biochemical Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tox.2017.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736314PMC
December 2017

The international MAQC Society launches to enhance reproducibility of high-throughput technologies.

Nat Biotechnol 2017 12;35(12):1127-1128

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA.

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http://dx.doi.org/10.1038/nbt.4029DOI Listing
December 2017

MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation.

Biochem Pharmacol 2017 09 26;140:139-149. Epub 2017 May 26.

National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687086PMC
September 2017

A systematic evaluation of microRNAs in regulating human hepatic CYP2E1.

Biochem Pharmacol 2017 08 22;138:174-184. Epub 2017 Apr 22.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703043PMC
August 2017

Activation of the Nrf2 signaling pathway in usnic acid-induced toxicity in HepG2 cells.

Arch Toxicol 2017 Mar 1;91(3):1293-1307. Epub 2016 Jul 1.

Division of Biochemical Toxicology, National Center for Toxicological Research (NCTR)/U.S. Food and Drug Administration (FDA), HFT-110, 3900 NCTR Road, Jefferson, AR, 72079, USA.

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http://dx.doi.org/10.1007/s00204-016-1775-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727582PMC
March 2017

Significant variations in alternative splicing patterns and expression profiles between human-mouse orthologs in early embryos.

Sci China Life Sci 2017 Feb 4;60(2):178-188. Epub 2016 Jul 4.

The Center for Bioinformatics and Computational Biology, Shanghai Key Laboratory of Regulatory Biology, the Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.

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http://dx.doi.org/10.1007/s11427-015-0348-5DOI Listing
February 2017

Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.

Chem Biol Interact 2016 Aug 22;255:63-73. Epub 2015 Oct 22.

Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2015.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727584PMC
August 2016

HLADR: a database system for enhancing the discovery of biomarkers for predicting human leukocyte antigen-mediated idiosyncratic adverse drug reactions.

Biomark Med 2015 26;9(11):1079-93. Epub 2015 Oct 26.

Center for Pharmacogenomics & State Key Laboratory of Genetic Engineering, School of Life Sciences & School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China.

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http://dx.doi.org/10.2217/bmm.15.98DOI Listing
August 2016

microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment.

Biomark Med 2015 26;9(11):1153-76. Epub 2015 Oct 26.

National Center for Toxicological Research, US Food & Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.2217/bmm.15.89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712454PMC
August 2016

MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes.

Biochem Pharmacol 2016 08 14;113:88-96. Epub 2016 Jun 14.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2016.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672627PMC
August 2016

The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.

Toxicol Lett 2016 Jun 22;253:55-62. Epub 2016 Apr 22.

Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2016.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727580PMC
June 2016

Challenges, Solutions, and Quality Metrics of Personal Genome Assembly in Advancing Precision Medicine.

Pharmaceutics 2016 Apr 22;8(2). Epub 2016 Apr 22.

National Center for Toxicological Research, U.S. Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.3390/pharmaceutics8020015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932478PMC
April 2016

Single nucleotide polymorphism rs11669203 in TGFBR3L is associated with the risk of neuroblastoma in a Chinese population.

Tumour Biol 2016 Mar 14;37(3):3739-47. Epub 2015 Oct 14.

Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, Beijing, China.

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http://link.springer.com/10.1007/s13277-015-4192-6
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http://dx.doi.org/10.1007/s13277-015-4192-6DOI Listing
March 2016

Functional single nucleotide polymorphism in IL-17A 3' untranslated region is targeted by miR-4480 in vitro and may be associated with age-related macular degeneration.

Environ Mol Mutagen 2016 Jan 10;57(1):58-64. Epub 2015 Sep 10.

Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/em.21982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714768PMC
January 2016

Whole genome and normalized mRNA sequencing reveal genetic status of TK6, WTK1, and NH32 human B-lymphoblastoid cell lines.

Mutat Res Genet Toxicol Environ Mutagen 2016 Jan 17;795:60-9. Epub 2015 Nov 17.

Division of Genetic and Molecular Toxicology, FDA/NCTR, Jefferson, AR 72079, United States.

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http://dx.doi.org/10.1016/j.mrgentox.2015.11.006DOI Listing
January 2016

Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells.

Biochem Pharmacol 2015 Dec 30;98(4):671-80. Epub 2015 Sep 30.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705000PMC
December 2015

MicroRNA hsa-miR-29a-3p modulates CYP2C19 in human liver cells.

Biochem Pharmacol 2015 Nov 19;98(1):215-23. Epub 2015 Aug 19.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.08.094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673105PMC
November 2015

Re-annotation of presumed noncoding disease/trait-associated genetic variants by integrative analyses.

Sci Rep 2015 Mar 30;5:9453. Epub 2015 Mar 30.

The Center for Bioinformatics and Computational Biology, Shanghai Key Laboratory of Regulatory Biology, the Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.

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http://dx.doi.org/10.1038/srep09453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377585PMC
March 2015

Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma.

Sci Rep 2015 Feb 23;5:8534. Epub 2015 Feb 23.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1038/srep08534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336941PMC
February 2015

Toxicogenomics and cancer susceptibility: advances with next-generation sequencing.

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2014 ;32(2):121-58

a National Center for Toxicological Research , Food and Drug Administration , Jefferson , Arkansas , USA.

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http://dx.doi.org/10.1080/10590501.2014.907460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712441PMC
January 2015

Gene expression variability in human hepatic drug metabolizing enzymes and transporters.

PLoS One 2013 23;8(4):e60368. Epub 2013 Apr 23.

Division of Systems Biology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060368PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634068PMC
November 2013

GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer.

Pharmgenomics Pers Med 2013 1;6:9-17. Epub 2013 Mar 1.

University of Arkansas for Medical Sciences, Little Rock, Arkansas, US Food and Drug Administration, Jefferson, Arkansas, USA.

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http://dx.doi.org/10.2147/PGPM.S35949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596140PMC
April 2013

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine.

Sci China Life Sci 2013 Feb 8;56(2):110-8. Epub 2013 Feb 8.

Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA.

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http://link.springer.com/content/pdf/10.1007/s11427-013-4439
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http://link.springer.com/10.1007/s11427-013-4439-7
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http://dx.doi.org/10.1007/s11427-013-4439-7DOI Listing
February 2013

Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine.

Sci China Life Sci 2013 Feb 8;56(2):119-24. Epub 2013 Feb 8.

Division of Systems Biology, National Center for Toxicological Research, the US Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1007/s11427-013-4438-8DOI Listing
February 2013

Association between GSTM1 copy number, promoter variants and susceptibility to urinary bladder cancer.

Int J Mol Epidemiol Genet 2012 31;3(3):228-36. Epub 2012 Aug 31.

University of Arkansas for Medical Sciences Little Rock, AR 72205.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459215PMC
October 2012

Differential promoter activities of functional haplotypes in the 5'-flanking region of human sulfotransferase 1A1.

J Biochem Mol Toxicol 2012 Oct;26(10):422-8

Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1002/jbt.21437DOI Listing
October 2012

Sex Differences in the Expression of Drug-Metabolizing and Transporter Genes in Human Liver.

J Drug Metab Toxicol 2012 10;3(3):1000119. Epub 2012 Jul 10.

Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.4172/2157-7609.1000119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699760PMC
July 2012

Cytotoxicity and inhibitory effects of low-concentration triclosan on adipogenic differentiation of human mesenchymal stem cells.

Toxicol Appl Pharmacol 2012 Jul 1;262(2):117-23. Epub 2012 May 1.

Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1016/j.taap.2012.04.024DOI Listing
July 2012

Sulfation of fulvestrant by human liver cytosols and recombinant SULT1A1 and SULT1E1.

Pharmgenomics Pers Med 2011 Nov;4:137-145

Division of Medical genetics, college of Medicine, University of Arkansas for Medical sciences, Little rock, AR, USA.

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http://dx.doi.org/10.2147/PGPM.S25418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400326PMC
November 2011

Assessment of research models for testing gene-environment interactions.

Eur J Pharmacol 2011 Sep 27;668 Suppl 1:S108-16. Epub 2011 Jul 27.

Division of Personalized Nutrition and Medicine, NCTR/FDA, 3900 NCTR Rd., Jefferson, AR 72079, United States.

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http://dx.doi.org/10.1016/j.ejphar.2011.05.084DOI Listing
September 2011

Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys.

Chem Res Toxicol 2011 Sep 23;24(9):1486-93. Epub 2011 Aug 23.

ICF International at FDA's National Center for Toxicological Research, 3900 NCTR Road, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1021/tx200103bDOI Listing
September 2011

Next-generation sequencing and its applications in molecular diagnostics.

Expert Rev Mol Diagn 2011 Apr;11(3):333-43

Z-Tech, an ICF International Company at US FDA's National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1586/erm.11.3DOI Listing
April 2011

Similarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes.

Drug Metab Dispos 2011 Mar 13;39(3):528-38. Epub 2010 Dec 13.

Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1124/dmd.110.035873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061558PMC
March 2011

Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity.

Toxicol Sci 2010 Dec 29;118(2):391-403. Epub 2010 Sep 29.

Division of Medical Genetics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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http://dx.doi.org/10.1093/toxsci/kfq296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984532PMC
December 2010

Two new ArrayTrack libraries for personalized biomedical research.

BMC Bioinformatics 2010 Oct 7;11 Suppl 6:S6. Epub 2010 Oct 7.

Z-Tech Corporation, ICF International company at NCTR, National Center for Toxicological Research, 3900 NCTR Rd, Jefferson, AR 72079, USA.

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http://dx.doi.org/10.1186/1471-2105-11-S6-S6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026380PMC
October 2010

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.

Authors:
Leming Shi Gregory Campbell Wendell D Jones Fabien Campagne Zhining Wen Stephen J Walker Zhenqiang Su Tzu-Ming Chu Federico M Goodsaid Lajos Pusztai John D Shaughnessy André Oberthuer Russell S Thomas Richard S Paules Mark Fielden Bart Barlogie Weijie Chen Pan Du Matthias Fischer Cesare Furlanello Brandon D Gallas Xijin Ge Dalila B Megherbi W Fraser Symmans May D Wang John Zhang Hans Bitter Benedikt Brors Pierre R Bushel Max Bylesjo Minjun Chen Jie Cheng Jing Cheng Jeff Chou Timothy S Davison Mauro Delorenzi Youping Deng Viswanath Devanarayan David J Dix Joaquin Dopazo Kevin C Dorff Fathi Elloumi Jianqing Fan Shicai Fan Xiaohui Fan Hong Fang Nina Gonzaludo Kenneth R Hess Huixiao Hong Jun Huan Rafael A Irizarry Richard Judson Dilafruz Juraeva Samir Lababidi Christophe G Lambert Li Li Yanen Li Zhen Li Simon M Lin Guozhen Liu Edward K Lobenhofer Jun Luo Wen Luo Matthew N McCall Yuri Nikolsky Gene A Pennello Roger G Perkins Reena Philip Vlad Popovici Nathan D Price Feng Qian Andreas Scherer Tieliu Shi Weiwei Shi Jaeyun Sung Danielle Thierry-Mieg Jean Thierry-Mieg Venkata Thodima Johan Trygg Lakshmi Vishnuvajjala Sue Jane Wang Jianping Wu Yichao Wu Qian Xie Waleed A Yousef Liang Zhang Xuegong Zhang Sheng Zhong Yiming Zhou Sheng Zhu Dhivya Arasappan Wenjun Bao Anne Bergstrom Lucas Frank Berthold Richard J Brennan Andreas Buness Jennifer G Catalano Chang Chang Rong Chen Yiyu Cheng Jian Cui Wendy Czika Francesca Demichelis Xutao Deng Damir Dosymbekov Roland Eils Yang Feng Jennifer Fostel Stephanie Fulmer-Smentek James C Fuscoe Laurent Gatto Weigong Ge Darlene R Goldstein Li Guo Donald N Halbert Jing Han Stephen C Harris Christos Hatzis Damir Herman Jianping Huang Roderick V Jensen Rui Jiang Charles D Johnson Giuseppe Jurman Yvonne Kahlert Sadik A Khuder Matthias Kohl Jianying Li Li Li Menglong Li Quan-Zhen Li Shao Li Zhiguang Li Jie Liu Ying Liu Zhichao Liu Lu Meng Manuel Madera Francisco Martinez-Murillo Ignacio Medina Joseph Meehan Kelci Miclaus Richard A Moffitt David Montaner Piali Mukherjee George J Mulligan Padraic Neville Tatiana Nikolskaya Baitang Ning Grier P Page Joel Parker R Mitchell Parry Xuejun Peng Ron L Peterson John H Phan Brian Quanz Yi Ren Samantha Riccadonna Alan H Roter Frank W Samuelson Martin M Schumacher Joseph D Shambaugh Qiang Shi Richard Shippy Shengzhu Si Aaron Smalter Christos Sotiriou Mat Soukup Frank Staedtler Guido Steiner Todd H Stokes Qinglan Sun Pei-Yi Tan Rong Tang Zivana Tezak Brett Thorn Marina Tsyganova Yaron Turpaz Silvia C Vega Roberto Visintainer Juergen von Frese Charles Wang Eric Wang Junwei Wang Wei Wang Frank Westermann James C Willey Matthew Woods Shujian Wu Nianqing Xiao Joshua Xu Lei Xu Lun Yang Xiao Zeng Jialu Zhang Li Zhang Min Zhang Chen Zhao Raj K Puri Uwe Scherf Weida Tong Russell D Wolfinger

Nat Biotechnol 2010 Aug 30;28(8):827-38. Epub 2010 Jul 30.

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA.

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http://dx.doi.org/10.1038/nbt.1665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315840PMC
August 2010

Systematic and simultaneous gene profiling of 84 drug-metabolizing genes in primary human hepatocytes.

J Biomol Screen 2008 Mar 12;13(3):194-201. Epub 2008 Feb 12.

Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1177/1087057108315513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739314PMC
March 2008

Patterns and trends of pancreatic cancer mortality rates in Arkansas, 1969-2002: a comparison with the US population.

Eur J Cancer Prev 2008 Feb;17(1):18-27

Department of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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http://dx.doi.org/10.1097/CEJ.0b013e32809b4ccdDOI Listing
February 2008

A variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer.

Hum Mutat 2008 Jan;29(1):113-22

Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas, USA.

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http://doi.wiley.com/10.1002/humu.20610
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http://dx.doi.org/10.1002/humu.20610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441604PMC
January 2008

Plasma carotenoids and prostate cancer: a population-based case-control study in Arkansas.

Nutr Cancer 2007 ;59(1):46-53

Department of Epidemiology, Fay W Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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http://dx.doi.org/10.1080/01635580701385900DOI Listing
January 2008

Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin.

Mol Pharmacol 2007 Dec 17;72(6):1637-46. Epub 2007 Sep 17.

Division of Pharmacogenomics and Molecular Epidemiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.107.03
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http://dx.doi.org/10.1124/mol.107.039644DOI Listing
December 2007

An apolipoprotein E variant may protect against age-related macular degeneration through cytokine regulation.

Environ Mol Mutagen 2006 Oct;47(8):594-602

Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1857, USA.

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http://dx.doi.org/10.1002/em.20233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899525PMC
October 2006

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.

Authors:
Leming Shi Laura H Reid Wendell D Jones Richard Shippy Janet A Warrington Shawn C Baker Patrick J Collins Francoise de Longueville Ernest S Kawasaki Kathleen Y Lee Yuling Luo Yongming Andrew Sun James C Willey Robert A Setterquist Gavin M Fischer Weida Tong Yvonne P Dragan David J Dix Felix W Frueh Frederico M Goodsaid Damir Herman Roderick V Jensen Charles D Johnson Edward K Lobenhofer Raj K Puri Uwe Schrf Jean Thierry-Mieg Charles Wang Mike Wilson Paul K Wolber Lu Zhang Shashi Amur Wenjun Bao Catalin C Barbacioru Anne Bergstrom Lucas Vincent Bertholet Cecilie Boysen Bud Bromley Donna Brown Alan Brunner Roger Canales Xiaoxi Megan Cao Thomas A Cebula James J Chen Jing Cheng Tzu-Ming Chu Eugene Chudin John Corson J Christopher Corton Lisa J Croner Christopher Davies Timothy S Davison Glenda Delenstarr Xutao Deng David Dorris Aron C Eklund Xiao-hui Fan Hong Fang Stephanie Fulmer-Smentek James C Fuscoe Kathryn Gallagher Weigong Ge Lei Guo Xu Guo Janet Hager Paul K Haje Jing Han Tao Han Heather C Harbottle Stephen C Harris Eli Hatchwell Craig A Hauser Susan Hester Huixiao Hong Patrick Hurban Scott A Jackson Hanlee Ji Charles R Knight Winston P Kuo J Eugene LeClerc Shawn Levy Quan-Zhen Li Chunmei Liu Ying Liu Michael J Lombardi Yunqing Ma Scott R Magnuson Botoul Maqsodi Tim McDaniel Nan Mei Ola Myklebost Baitang Ning Natalia Novoradovskaya Michael S Orr Terry W Osborn Adam Papallo Tucker A Patterson Roger G Perkins Elizabeth H Peters Ron Peterson Kenneth L Philips P Scott Pine Lajos Pusztai Feng Qian Hongzu Ren Mitch Rosen Barry A Rosenzweig Raymond R Samaha Mark Schena Gary P Schroth Svetlana Shchegrova Dave D Smith Frank Staedtler Zhenqiang Su Hongmei Sun Zoltan Szallasi Zivana Tezak Danielle Thierry-Mieg Karol L Thompson Irina Tikhonova Yaron Turpaz Beena Vallanat Christophe Van Stephen J Walker Sue Jane Wang Yonghong Wang Russ Wolfinger Alex Wong Jie Wu Chunlin Xiao Qian Xie Jun Xu Wen Yang Liang Zhang Sheng Zhong Yaping Zong William Slikker

Nat Biotechnol 2006 Sep;24(9):1151-61

National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA.

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http://dx.doi.org/10.1038/nbt1239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272078PMC
September 2006

Synergic effect of polymorphisms in ERCC6 5' flanking region and complement factor H on age-related macular degeneration predisposition.

Proc Natl Acad Sci U S A 2006 Jun 5;103(24):9256-61. Epub 2006 Jun 5.

Division of Epidemiology and Clinical Research, and Ophthalmic Genetics and Visual Function Branch, Section on Ophthalmic Molecular Genetics, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0603485103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474016PMC
June 2006

Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer.

Gastroenterology 2005 Aug;129(2):565-76

Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1016/j.gastro.2005.05.003DOI Listing
August 2005

Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.

Pharmacogenetics 2004 Jan;14(1):35-44

National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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January 2004