Publications by authors named "Baerbel Rohrer"

33Publications

Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System.

Front Immunol 2020 24;11:566892. Epub 2020 Sep 24.

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, United States.

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http://dx.doi.org/10.3389/fimmu.2020.566892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541817PMC
September 2020

Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis.

J Neurochem 2016 10 27;139(2):270-284. Epub 2016 Sep 27.

Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056830PMC
http://dx.doi.org/10.1111/jnc.13770DOI Listing
October 2016

Calpain inhibition attenuates apoptosis of retinal ganglion cells in acute optic neuritis.

Invest Ophthalmol Vis Sci 2011 Jul 1;52(7):4935-41. Epub 2011 Jul 1.

Departments of Neurosciences, Division of Neurology, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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http://dx.doi.org/10.1167/iovs.10-7027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175948PMC
July 2011

A nonparametric approach to detect nonlinear correlation in gene expression.

J Comput Graph Stat 2010 Sep;19(3):552-568

Department of Biostatistics, Moffitt Cancer Center, Tampa, FL, USA,

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http://dx.doi.org/10.1198/jcgs.2010.08160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945392PMC
September 2010

Assessing the functional coherence of gene sets with metrics based on the Gene Ontology graph.

Bioinformatics 2010 Jun;26(12):i79-87

Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1093/bioinformatics/btq203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881388PMC
June 2010

Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism.

J Neurosci 2010 Feb;30(7):2496-503

Department of Ophthalmology, Division of Research, Medical University of South Carolina, Charleston, South Carolina 29412, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.6254-09.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849294PMC
February 2010

Rpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis.

Invest Ophthalmol Vis Sci 2008 Jun 22;49(6):2384-9. Epub 2008 Feb 22.

Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina 29402, USA.

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http://dx.doi.org/10.1167/iovs.08-1727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2641010PMC
June 2008

S-nitrosoglutathione prevents interphotoreceptor retinoid-binding protein (IRBP(161-180))-induced experimental autoimmune uveitis.

J Ocul Pharmacol Ther 2007 Jun;23(3):221-31

Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1089/jop.2007.0023DOI Listing
June 2007

Rod and cone pigment regeneration in RPE65-/- mice.

Adv Exp Med Biol 2006 ;572:101-7

Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1007/0-387-32442-9_16DOI Listing
April 2007

Long-term ERG analysis in the partially light-damaged mouse retina reveals regressive and compensatory changes.

Vis Neurosci 2006 Jan-Feb;23(1):91-7

Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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http://dx.doi.org/10.1017/S0952523806231080DOI Listing
June 2006

9-cis Retinal increased in retina of RPE65 knockout mice with decrease in coat pigmentation.

Photochem Photobiol 2006 Nov-Dec;82(6):1461-7

Department of Ophthalmology, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1562/2006-02-02-RA-793DOI Listing
April 2007

Gene silencing in Xenopus laevis by DNA vector-based RNA interference and transgenesis.

Cell Res 2006 Jan;16(1):99-105

Department of Neurosciences, Division of Research, Medical University of South Carolina, 167 Ashley Ave, SEI 511, Charleston, 29425, USA.

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http://dx.doi.org/10.1038/sj.cr.7310013DOI Listing
January 2006

Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal.

Invest Ophthalmol Vis Sci 2005 Oct;46(10):3876-82

Department of Ophthalmology, Medical University of South Carolina, Charleston, 29425, USA.

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http://dx.doi.org/10.1167/iovs.05-0533DOI Listing
October 2005

Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages.

Invest Ophthalmol Vis Sci 2005 Apr;46(4):1473-9

Departments of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://dx.doi.org/10.1167/iovs.04-0653DOI Listing
April 2005

Functionally intact glutamate-mediated signaling in bipolar cells of the TRKB knockout mouse retina.

Vis Neurosci 2004 Sep-Oct;21(5):703-13

Department of Ophthalmology, Medical University of South Carolina, Charlston, SC 29425, USA.

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http://dx.doi.org/10.1017/S095252380421505XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710101PMC
March 2005

Neurodegenerative alterations in the nigrostriatal system of trkB hypomorphic mice.

Exp Neurol 2004 Dec;190(2):337-46

Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1016/j.expneurol.2004.08.002DOI Listing
December 2004

Identification of RDH10, an All-trans Retinol Dehydrogenase, in Retinal Muller Cells.

Invest Ophthalmol Vis Sci 2004 Nov;45(11):3857-62

Department of Ophthalmology, Medical University of South Carolina, USA.

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http://dx.doi.org/10.1167/iovs.03-1302DOI Listing
November 2004

Multidestructive pathways triggered in photoreceptor cell death of the rd mouse as determined through gene expression profiling.

J Biol Chem 2004 Oct 24;279(40):41903-10. Epub 2004 Jun 24.

Departments of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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http://dx.doi.org/10.1074/jbc.M405085200DOI Listing
October 2004

Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line.

J Biol Chem 2004 Aug 18;279(34):35564-72. Epub 2004 Jun 18.

Department of Ophthalmology, Storm Eye Institute, University of South Carolina, Charleston 29425, USA.

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http://www.jbc.org/content/279/34/35564.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M401037200
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http://dx.doi.org/10.1074/jbc.M401037200DOI Listing
August 2004

Does constitutive phosphorylation protect against photoreceptor degeneration in Rpe65-/- mice?

Adv Exp Med Biol 2003 ;533:221-7

Department of Ophthalmology, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1007/978-1-4615-0067-4_28DOI Listing
August 2004

Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice.

Proc Natl Acad Sci U S A 2003 Nov 24;100(23):13662-7. Epub 2003 Oct 24.

Department of Ophthalmology, Medical University of South Carolina, 167 Ashley Avenue, Charleston, SC 29425, USA.

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http://www.pnas.org/content/100/23/13662.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.2234461100
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http://dx.doi.org/10.1073/pnas.2234461100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC263870PMC
November 2003

Structure-function analysis of rods and cones in juvenile, adult, and aged C57bl/6 and Balb/c mice.

Vis Neurosci 2003 Mar-Apr;20(2):211-20

Department of Ophthalmology, Medical University of South Carolina, Charleston 29425, USA.

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http://dx.doi.org/10.1017/s0952523803202108DOI Listing
November 2003

Retarded outer segment development in TrkB knockout mouse retina organ culture.

Mol Vis 2003 Jan 24;9:18-23. Epub 2003 Jan 24.

Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425, USA.

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January 2003

Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging.

Invest Ophthalmol Vis Sci 2003 Jan;44(1):310-5

Department of Ophthalmology Medical University of South Carolina, 167 Ashley Avenue, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1167/iovs.02-0567DOI Listing
January 2003

Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE.

Invest Ophthalmol Vis Sci 2002 Nov;43(11):3365-72

Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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November 2002

Synthesis, pharmacokinetics, efficacy, and rat retinal toxicity of a novel mitomycin C-triamcinolone acetonide conjugate.

J Med Chem 2002 Feb;45(5):1122-7

Department of Ophthalmology, Medical University of South Carolina, 280 Calhoun Street, Charleston, South Carolina 29425-2301, USA.

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http://dx.doi.org/10.1021/jm010511bDOI Listing
February 2002