Publications by authors named "Baek-Soo Han"

48Publications

GADD45β Regulates Hepatic Gluconeogenesis via Modulating the Protein Stability of FoxO1.

Biomedicines 2021 Jan 8;9(1). Epub 2021 Jan 8.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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January 2021

Myonectin inhibits adipogenesis in 3T3-L1 preadipocytes by regulating p38 MAPK pathway.

BMB Rep 2021 Jan 7. Epub 2021 Jan 7.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.

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January 2021

Selective elimination of human pluripotent stem cells by Anti-Dsg2 antibody-doxorubicin conjugates.

Biomaterials 2020 Nov 13;259:120265. Epub 2020 Aug 13.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea; Department of Biomolecular Science, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon, 34113, Republic of Korea. Electronic address:

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November 2020

The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene.

J Biol Chem 2020 Sep 5;295(39):13677-13690. Epub 2020 Aug 5.

Biodefence Research Center, Korea Research Institute of Bioscience and Biotechnology, Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea

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September 2020

Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation.

Sci Rep 2020 07 1;10(1):10755. Epub 2020 Jul 1.

Biodefense Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea.

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July 2020

Molecular Drug Discovery of Single Ginsenoside Compounds as a Potent Bruton's Tyrosine Kinase Inhibitor.

Int J Mol Sci 2020 Apr 26;21(9). Epub 2020 Apr 26.

MODNBIO Inc. digital road 34, Kolon Science Valley I, Guro-gu, Seoul 08378, Korea.

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April 2020

IDH1-dependent α-KG regulates brown fat differentiation and function by modulating histone methylation.

Metabolism 2020 04 5;105:154173. Epub 2020 Feb 5.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea. Electronic address:

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April 2020

Rapid differentiation of astrocytes from human embryonic stem cells.

Neurosci Lett 2020 01 10;716:134681. Epub 2019 Dec 10.

Research Center for Biodefence, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea. Electronic address:

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January 2020

Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation.

J Microbiol Biotechnol 2019 Apr;29(4):645-650

Metabolic Regulation Research Center, Division of BioMedical Sciences, KRIBB, Daejeon 34141, Republic of Korea.

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April 2019

DSG2 Is a Functional Cell Surface Marker for Identification and Isolation of Human Pluripotent Stem Cells.

Stem Cell Reports 2018 07 14;11(1):115-127. Epub 2018 Jun 14.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea; Department of Biomolecular Science, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea. Electronic address:

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July 2018

Daphnane and Phorbol Diterpenes, Anti-neuroinflammatory Compounds with Nurr1 Activation from the Roots and Stems of Daphne genkwa.

Biol Pharm Bull 2017 ;40(12):2205-2211

Superbacteria Research Center, Korea Research Institute of Bioscience and Biotechnology.

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July 2018

Genkwalathins A and B, new lathyrane-type diterpenes from Daphne genkwa.

Nat Prod Res 2018 Aug 20;32(15):1782-1790. Epub 2017 Nov 20.

a Superbacteria Research Center , Korea Research Institute of Bioscience and Biotechnology , Daejeon , Republic of Korea.

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August 2018

HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription.

Mol Cells 2017 Sep 20;40(9):667-676. Epub 2017 Sep 20.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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September 2017

Metabolic Adaptation in Obesity and Type II Diabetes: Myokines, Adipokines and Hepatokines.

Int J Mol Sci 2016 Dec 22;18(1). Epub 2016 Dec 22.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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December 2016

Graphene oxide induces apoptotic cell death in endothelial cells by activating autophagy via calcium-dependent phosphorylation of c-Jun N-terminal kinases.

Acta Biomater 2016 12 15;46:191-203. Epub 2016 Sep 15.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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December 2016

Daphnane Diterpenes from Daphne genkwa Activate Nurr1 and Have a Neuroprotective Effect in an Animal Model of Parkinson's Disease.

J Nat Prod 2016 06 26;79(6):1604-9. Epub 2016 May 26.

Superbacteria Research Center, Korea Research Institute of Bioscience and Biotechnology , Daejeon 34141, Republic of Korea.

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June 2016

Methyltransferase and demethylase profiling studies during brown adipocyte differentiation.

BMB Rep 2016 Jul;49(7):388-93

Metabolic Regulation Research Center, KRIBB; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 34141, Korea.

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July 2016

Set7/9, a methyltransferase, regulates the thermogenic program during brown adipocyte differentiation through the modulation of p53 acetylation.

Mol Cell Endocrinol 2016 08 29;431:46-53. Epub 2016 Apr 29.

Metabolic Regulation Research Center, Division of BioMedical Sciences, KRIBB, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon 305-806, Republic of Korea. Electronic address:

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August 2016

Use of Microfluidic Technology to Monitor the Differentiation and Migration of Human ESC-Derived Neural Cells.

Methods Mol Biol 2016 ;1502:223-35

CHA Stem Cell Institute, Department of Biomedical Science, CHA University, Rm 604, CHA Bio Complex, 335 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, Republic of Korea.

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January 2018

Profiling analysis of protein tyrosine phosphatases during neuronal differentiation.

Neurosci Lett 2016 Jan 15;612:219-224. Epub 2015 Dec 15.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea. Electronic address:

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January 2016

c-Jun regulates adipocyte differentiation via the KLF15-mediated mode.

Biochem Biophys Res Commun 2016 01 13;469(3):552-8. Epub 2015 Dec 13.

Functional Genomics Research Center, KRIBB, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 305-806, Republic of Korea. Electronic address:

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January 2016

Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis.

Biochem Biophys Res Commun 2015 Nov 9;467(2):211-7. Epub 2015 Oct 9.

Research Institute of Biomolecular Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address:

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November 2015

MAP kinase phosphatase 3 inhibits brown adipocyte differentiation via regulation of Erk phosphorylation.

Mol Cell Endocrinol 2015 Nov 29;416:70-6. Epub 2015 Aug 29.

Functional Genomics Research Center, KRIBB, Daejeon, 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology of Korea, Daejeon, 305-806, Republic of Korea. Electronic address:

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November 2015

Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody.

Biomaterials 2015 May 17;51:119-128. Epub 2015 Feb 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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May 2015

Recent advances in proteomic studies of adipose tissues and adipocytes.

Int J Mol Sci 2015 Feb 27;16(3):4581-99. Epub 2015 Feb 27.

Functional Genomics Research Center, KRIBB, Daejeon 305-806, Korea.

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February 2015

DUSP4 regulates neuronal differentiation and calcium homeostasis by modulating ERK1/2 phosphorylation.

Stem Cells Dev 2015 Mar 23;24(6):686-700. Epub 2014 Dec 23.

1 Department of Biological Sciences, Center for Stem Cell Differentiation, KAIST , Daejeon, Republic of Korea.

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March 2015

Identification of DNA aptamers toward epithelial cell adhesion molecule via cell-SELEX.

Mol Cells 2014 Oct 29;37(10):742-6. Epub 2014 Sep 29.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea ; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon 305-806, Korea.

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October 2014

Selection of aptamers for mature white adipocytes by cell SELEX using flow cytometry.

PLoS One 2014 20;9(5):e97747. Epub 2014 May 20.

Research Center for Integrated Cellulomics, KRIBB, Daejeon, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea.

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January 2015

Proteomic analysis of the effect of retinoic acids on the human breast cancer cell line MCF-7.

Mol Biol Rep 2014 May 11;41(5):3499-507. Epub 2014 Mar 11.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 305-806, Korea.

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May 2014

Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism.

Brain Res 2014 Mar 27;1552:72-81. Epub 2014 Jan 27.

Molecular Neurobiology Laboratory, McLean Hospital and Harvard Medical School, Belmont, MA 02478, USA. Electronic address:

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March 2014

Protein tyrosine phosphatase profiling studies during brown adipogenic differentiation of mouse primary brown preadipocytes.

BMB Rep 2013 Nov;46(11):539-43

Research Center for Integrated Cellulomics, KRIBB; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 305-806, Korea

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November 2013

Acceleration of adipogenic differentiation via acetylation of malate dehydrogenase 2.

Biochem Biophys Res Commun 2013 Nov 14;441(1):77-82. Epub 2013 Oct 14.

Research Center for Integrated Cellulomics, KRIBB, Daejeon 305-806, South Korea.

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November 2013

Investigation of adipocyte proteome during the differentiation of brown preadipocytes.

J Proteomics 2013 Dec 12;94:327-36. Epub 2013 Oct 12.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Republic of Korea.

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December 2013

Mechanisms to prevent caspase activation in rotenone-induced dopaminergic neurodegeneration: role of ATP depletion and procaspase-9 degradation.

Apoptosis 2012 Feb 1. Epub 2012 Feb 1.

Department of Biology, Yonsei University College of Life Science and Biotechnology, Seoul, 120-749, Korea.

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February 2012

Translocation and oligomerization of Bax is regulated independently by activation of p38 MAPK and caspase-2 during MN9D dopaminergic neurodegeneration.

Apoptosis 2011 Nov;16(11):1087-100

Department of Biology, Yonsei University College of Life Science and Biotechnology, 134 Shinchon-dong Seodaemoon-gu, Seoul 120-749, Korea.

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November 2011

LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity.

Exp Cell Res 2010 Feb 19;316(4):649-56. Epub 2009 Sep 19.

Institute for Brain Science and Technology, Busan, South Korea.

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February 2010

Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins.

Cell Stem Cell 2009 Jun 28;4(6):472-6. Epub 2009 May 28.

Molecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA.

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June 2009

Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra.

Neurosci Lett 2008 Sep 10;442(3):190-4. Epub 2008 Jul 10.

Molecular Neurobiology Laboratory, McLean Hospital, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.

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September 2008

A distinct death mechanism is induced by 1-methyl-4-phenylpyridinium or by 6-hydroxydopamine in cultured rat cortical neurons: degradation and dephosphorylation of tau.

Neurosci Lett 2003 May;341(2):99-102

Department of Biology, Yonsei University College of Science, 134 Shinchon-Dong, Seodaemoon-Gu, 120-749, Seoul, South Korea.

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May 2003