Publications by authors named "Baek Soo Han"

45Publications

Selective elimination of human pluripotent stem cells by Anti-Dsg2 antibody-doxorubicin conjugates.

Biomaterials 2020 Nov 13;259:120265. Epub 2020 Aug 13.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea; Department of Biomolecular Science, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon, 34113, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2020.120265DOI Listing
November 2020

The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 gene.

J Biol Chem 2020 Sep 5;295(39):13677-13690. Epub 2020 Aug 5.

Biodefence Research Center, Korea Research Institute of Bioscience and Biotechnology, Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea

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http://dx.doi.org/10.1074/jbc.RA120.013352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521637PMC
September 2020

Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation.

Sci Rep 2020 07 1;10(1):10755. Epub 2020 Jul 1.

Biodefense Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-020-67549-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329810PMC
July 2020

Molecular Drug Discovery of Single Ginsenoside Compounds as a Potent Bruton's Tyrosine Kinase Inhibitor.

Int J Mol Sci 2020 Apr 26;21(9). Epub 2020 Apr 26.

MODNBIO Inc. digital road 34, Kolon Science Valley I, Guro-gu, Seoul 08378, Korea.

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http://dx.doi.org/10.3390/ijms21093065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247683PMC
April 2020

IDH1-dependent α-KG regulates brown fat differentiation and function by modulating histone methylation.

Metabolism 2020 04 5;105:154173. Epub 2020 Feb 5.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon 34141, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2020.154173DOI Listing
April 2020

Rapid differentiation of astrocytes from human embryonic stem cells.

Neurosci Lett 2020 01 10;716:134681. Epub 2019 Dec 10.

Research Center for Biodefence, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2019.134681DOI Listing
January 2020

Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation.

J Microbiol Biotechnol 2019 Apr;29(4):645-650

Metabolic Regulation Research Center, Division of BioMedical Sciences, KRIBB, Daejeon 34141, Republic of Korea.

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http://dx.doi.org/10.4014/jmb.1810.10033DOI Listing
April 2019

DSG2 Is a Functional Cell Surface Marker for Identification and Isolation of Human Pluripotent Stem Cells.

Stem Cell Reports 2018 07 14;11(1):115-127. Epub 2018 Jun 14.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea; Department of Biomolecular Science, KRIBB School of Bioscience, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34141, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117473PMC
July 2018

Daphnane and Phorbol Diterpenes, Anti-neuroinflammatory Compounds with Nurr1 Activation from the Roots and Stems of Daphne genkwa.

Biol Pharm Bull 2017 ;40(12):2205-2211

Superbacteria Research Center, Korea Research Institute of Bioscience and Biotechnology.

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http://dx.doi.org/10.1248/bpb.b17-00641DOI Listing
July 2018

Genkwalathins A and B, new lathyrane-type diterpenes from Daphne genkwa.

Nat Prod Res 2018 Aug 20;32(15):1782-1790. Epub 2017 Nov 20.

a Superbacteria Research Center , Korea Research Institute of Bioscience and Biotechnology , Daejeon , Republic of Korea.

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http://dx.doi.org/10.1080/14786419.2017.1402322DOI Listing
August 2018

HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription.

Mol Cells 2017 Sep 20;40(9):667-676. Epub 2017 Sep 20.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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http://www.molcells.org/journal/view.html?doi=10.14348/molce
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http://dx.doi.org/10.14348/molcells.2017.0116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638774PMC
September 2017

Metabolic Adaptation in Obesity and Type II Diabetes: Myokines, Adipokines and Hepatokines.

Int J Mol Sci 2016 Dec 22;18(1). Epub 2016 Dec 22.

Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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http://dx.doi.org/10.3390/ijms18010008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297643PMC
December 2016

Graphene oxide induces apoptotic cell death in endothelial cells by activating autophagy via calcium-dependent phosphorylation of c-Jun N-terminal kinases.

Acta Biomater 2016 12 15;46:191-203. Epub 2016 Sep 15.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.09.018DOI Listing
December 2016

Daphnane Diterpenes from Daphne genkwa Activate Nurr1 and Have a Neuroprotective Effect in an Animal Model of Parkinson's Disease.

J Nat Prod 2016 06 26;79(6):1604-9. Epub 2016 May 26.

Superbacteria Research Center, Korea Research Institute of Bioscience and Biotechnology , Daejeon 34141, Republic of Korea.

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http://dx.doi.org/10.1021/acs.jnatprod.6b00110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635821PMC
June 2016

Methyltransferase and demethylase profiling studies during brown adipocyte differentiation.

BMB Rep 2016 Jul;49(7):388-93

Metabolic Regulation Research Center, KRIBB; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 34141, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032007PMC
http://dx.doi.org/10.5483/bmbrep.2016.49.7.062DOI Listing
July 2016

Set7/9, a methyltransferase, regulates the thermogenic program during brown adipocyte differentiation through the modulation of p53 acetylation.

Mol Cell Endocrinol 2016 08 29;431:46-53. Epub 2016 Apr 29.

Metabolic Regulation Research Center, Division of BioMedical Sciences, KRIBB, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon 305-806, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2016.04.022DOI Listing
August 2016

Use of Microfluidic Technology to Monitor the Differentiation and Migration of Human ESC-Derived Neural Cells.

Methods Mol Biol 2016 ;1502:223-35

CHA Stem Cell Institute, Department of Biomedical Science, CHA University, Rm 604, CHA Bio Complex, 335 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, Republic of Korea.

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http://dx.doi.org/10.1007/7651_2016_337DOI Listing
January 2018

Profiling analysis of protein tyrosine phosphatases during neuronal differentiation.

Neurosci Lett 2016 Jan 15;612:219-224. Epub 2015 Dec 15.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2015.12.027DOI Listing
January 2016

c-Jun regulates adipocyte differentiation via the KLF15-mediated mode.

Biochem Biophys Res Commun 2016 01 13;469(3):552-8. Epub 2015 Dec 13.

Functional Genomics Research Center, KRIBB, Daejeon 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 305-806, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.12.035DOI Listing
January 2016

Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis.

Biochem Biophys Res Commun 2015 Nov 9;467(2):211-7. Epub 2015 Oct 9.

Research Institute of Biomolecular Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X153070
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http://dx.doi.org/10.1016/j.bbrc.2015.10.004DOI Listing
November 2015

MAP kinase phosphatase 3 inhibits brown adipocyte differentiation via regulation of Erk phosphorylation.

Mol Cell Endocrinol 2015 Nov 29;416:70-6. Epub 2015 Aug 29.

Functional Genomics Research Center, KRIBB, Daejeon, 305-806, Republic of Korea; Department of Functional Genomics, University of Science and Technology of Korea, Daejeon, 305-806, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.08.023DOI Listing
November 2015

Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody.

Biomaterials 2015 May 17;51:119-128. Epub 2015 Feb 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.01.062DOI Listing
May 2015

Recent advances in proteomic studies of adipose tissues and adipocytes.

Int J Mol Sci 2015 Feb 27;16(3):4581-99. Epub 2015 Feb 27.

Functional Genomics Research Center, KRIBB, Daejeon 305-806, Korea.

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http://dx.doi.org/10.3390/ijms16034581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394436PMC
February 2015

DUSP4 regulates neuronal differentiation and calcium homeostasis by modulating ERK1/2 phosphorylation.

Stem Cells Dev 2015 Mar 23;24(6):686-700. Epub 2014 Dec 23.

1 Department of Biological Sciences, Center for Stem Cell Differentiation, KAIST , Daejeon, Republic of Korea.

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http://dx.doi.org/10.1089/scd.2014.0434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356191PMC
March 2015

Identification of DNA aptamers toward epithelial cell adhesion molecule via cell-SELEX.

Mol Cells 2014 Oct 29;37(10):742-6. Epub 2014 Sep 29.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea ; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon 305-806, Korea.

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http://dx.doi.org/10.14348/molcells.2014.0208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213765PMC
October 2014

Selection of aptamers for mature white adipocytes by cell SELEX using flow cytometry.

PLoS One 2014 20;9(5):e97747. Epub 2014 May 20.

Research Center for Integrated Cellulomics, KRIBB, Daejeon, Republic of Korea; Department of Functional Genomics, University of Science and Technology (UST) of Korea, Daejeon, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097747PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028271PMC
January 2015

Proteomic analysis of the effect of retinoic acids on the human breast cancer cell line MCF-7.

Mol Biol Rep 2014 May 11;41(5):3499-507. Epub 2014 Mar 11.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 305-806, Korea.

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http://dx.doi.org/10.1007/s11033-014-3212-8DOI Listing
May 2014

Protein tyrosine phosphatase profiling studies during brown adipogenic differentiation of mouse primary brown preadipocytes.

BMB Rep 2013 Nov;46(11):539-43

Research Center for Integrated Cellulomics, KRIBB; Department of Functional Genomics, University of Science and Technology (UST), Daejeon 305-806, Korea

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133841PMC
http://dx.doi.org/10.5483/bmbrep.2013.46.11.058DOI Listing
November 2013

Acceleration of adipogenic differentiation via acetylation of malate dehydrogenase 2.

Biochem Biophys Res Commun 2013 Nov 14;441(1):77-82. Epub 2013 Oct 14.

Research Center for Integrated Cellulomics, KRIBB, Daejeon 305-806, South Korea.

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http://dx.doi.org/10.1016/j.bbrc.2013.10.016DOI Listing
November 2013

Investigation of adipocyte proteome during the differentiation of brown preadipocytes.

J Proteomics 2013 Dec 12;94:327-36. Epub 2013 Oct 12.

Research Center for Integrated Cellulomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Republic of Korea.

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http://dx.doi.org/10.1016/j.jprot.2013.10.005DOI Listing
December 2013

Korean mistletoe (Viscum album coloratum) extract improves endurance capacity in mice by stimulating mitochondrial activity.

J Med Food 2012 Jul 21;15(7):621-8. Epub 2012 May 21.

School of Life and Food Sciences, Handong Global University, Pohang, Gyungbuk, Korea.

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http://dx.doi.org/10.1089/jmf.2010.1469DOI Listing
July 2012

Protein tyrosine phosphatase profiling analysis of HIB-1B cells during brown adipogenesis.

J Microbiol Biotechnol 2012 Jul;22(7):1029-33

Medical Proteomics Research Center, KRIBB, Daejeon 305-806, Korea.

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http://dx.doi.org/10.4014/jmb.1112.12059DOI Listing
July 2012

Mechanisms to prevent caspase activation in rotenone-induced dopaminergic neurodegeneration: role of ATP depletion and procaspase-9 degradation.

Apoptosis 2012 Feb 1. Epub 2012 Feb 1.

Department of Biology, Yonsei University College of Life Science and Biotechnology, Seoul, 120-749, Korea.

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http://dx.doi.org/10.1007/s10495-012-0699-0DOI Listing
February 2012

Translocation and oligomerization of Bax is regulated independently by activation of p38 MAPK and caspase-2 during MN9D dopaminergic neurodegeneration.

Apoptosis 2011 Nov;16(11):1087-100

Department of Biology, Yonsei University College of Life Science and Biotechnology, 134 Shinchon-dong Seodaemoon-gu, Seoul 120-749, Korea.

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http://dx.doi.org/10.1007/s10495-011-0627-8DOI Listing
November 2011

LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity.

Exp Cell Res 2010 Feb 19;316(4):649-56. Epub 2009 Sep 19.

Institute for Brain Science and Technology, Busan, South Korea.

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http://dx.doi.org/10.1016/j.yexcr.2009.09.014DOI Listing
February 2010

Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins.

Cell Stem Cell 2009 Jun 28;4(6):472-6. Epub 2009 May 28.

Molecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA.

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http://dx.doi.org/10.1016/j.stem.2009.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705327PMC
June 2009

Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra.

Neurosci Lett 2008 Sep 10;442(3):190-4. Epub 2008 Jul 10.

Molecular Neurobiology Laboratory, McLean Hospital, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.

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http://dx.doi.org/10.1016/j.neulet.2008.06.086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737127PMC
September 2008

LRRK2 regulates synaptic vesicle endocytosis.

Exp Cell Res 2008 Jun 5;314(10):2055-65. Epub 2008 Mar 5.

Department of Life Science, GIST, Buk-gu, Gwangju, South Korea.

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http://dx.doi.org/10.1016/j.yexcr.2008.02.015DOI Listing
June 2008

A distinct death mechanism is induced by 1-methyl-4-phenylpyridinium or by 6-hydroxydopamine in cultured rat cortical neurons: degradation and dephosphorylation of tau.

Neurosci Lett 2003 May;341(2):99-102

Department of Biology, Yonsei University College of Science, 134 Shinchon-Dong, Seodaemoon-Gu, 120-749, Seoul, South Korea.

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http://dx.doi.org/10.1016/s0304-3940(03)00173-3DOI Listing
May 2003