Bernd Lahrmann

Bernd Lahrmann

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Bernd Lahrmann

Bernd Lahrmann

Publications by authors named "Bernd Lahrmann"

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34Publications

437Reads

High numbers of PDCD1 (PD-1)-positive T cells and mutations in microsatellite-unstable colorectal cancer.

Oncoimmunology 2018 6;7(2):e1390640. Epub 2017 Nov 6.

Department of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL Heidelberg.

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November 2017

Spatial intratumoral heterogeneity of proliferation in immunohistochemical images of solid tumors.

Med Phys 2016 Jun;43(6):2936-2947

Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg 69120, Germany.

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June 2016

Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts.

Anticancer Res 2016 Apr;36(4):1489-96

Division of Neurosurgical Research, Department of Neurosurgery, Hamamatsu Tissue Imaging and Analysis Center, University of Heidelberg, Heidelberg, Germany

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April 2016

Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters.

PLoS One 2015 27;10(3):e0121980. Epub 2015 Mar 27.

Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Im Neuenheimer Feld 280, Heidelberg, Germany.

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March 2016

Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer.

Oncoimmunology 2016 Feb 11;5(2):e1075692. Epub 2015 Nov 11.

Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Im Neuenheimer Feld 280, Heidelberg, Germany, and Molecular Medicine Partnership Unit, University Hospital Heidelberg and EMBL Heidelberg , Germany.

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February 2016

Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma.

Naunyn Schmiedebergs Arch Pharmacol 2015 Nov 4;388(11):1141-50. Epub 2015 Jul 4.

Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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November 2015

Association of drug transporter expression with mortality and progression-free survival in stage IV head and neck squamous cell carcinoma.

PLoS One 2014 2;9(9):e108908. Epub 2014 Oct 2.

Molecular Cell Biology Group, Department of Otorhinolaryngology, Head and Neck Surgery, University of Heidelberg, Heidelberg, Germany.

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June 2015

Semantic focusing allows fully automated single-layer slide scanning of cervical cytology slides.

PLoS One 2013 9;8(4):e61441. Epub 2013 Apr 9.

Hamamatsu Tissue Imaging and Analysis Center (TIGA), BIOQUANT, University Heidelberg, Heidelberg, Germany.

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October 2013

Identification of oropharyngeal squamous cell carcinomas with active HPV16 involvement by immunohistochemical analysis of the retinoblastoma protein pathway.

Int J Cancer 2013 Sep 29;133(6):1389-99. Epub 2013 Mar 29.

Department of Otolaryngology, Experimental Head and Neck Oncology, Head and Neck Surgery, Heidelberg University, Germany.

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September 2013

Sequence mutations of the substrate binding pocket of stem cell factor and multidrug resistance protein ABCG2 in renal cell cancer: a possible link to treatment resistance.

Oncol Rep 2013 May 5;29(5):1697-700. Epub 2013 Mar 5.

Department of Medical Oncology, National Center for Tumor Diseases, University of Heidelberg, D-69120 Heidelberg, Germany.

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May 2013

Hepatic metastases of colorectal cancer are rather homogeneous but differ from primary lesions in terms of immune cell infiltration.

Oncoimmunology 2013 Apr;2(4):e24116

National Center for Tumor Diseases; Medical Oncology and Internal Medicine VI; University Hospital Heidelberg; Heidelberg, Germany ; Tissue Imaging and Analysis Center (TIGA); BIOQUANT; Heidelberg, Germany.

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April 2013

Submaxillary gland androgen-regulated protein 3A expression is an unfavorable risk factor for the survival of oropharyngeal squamous cell carcinoma patients after surgery.

Eur Arch Otorhinolaryngol 2013 Mar 5;270(4):1493-500. Epub 2012 Oct 5.

Experimental Head and Neck Oncology, Department of Otolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

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March 2013

Multistage histopathological image segmentation of Iba1-stained murine microglias in a focal ischemia model: methodological workflow and expert validation.

J Neurosci Methods 2013 Mar 27;213(2):250-62. Epub 2012 Dec 27.

Hamamatsu Tissue Imaging and Analysis Center, Bioquant, Department of Medical Oncology, National Center for Tumour Diseases, Heidelberg University, Im Neuenheimer Feld 267 (BQ 0010), D-69120 Heidelberg, Germany.

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March 2013

Sequential metastases of colorectal cancer: Immunophenotypes and spatial distributions of infiltrating immune cells in relation to time and treatments.

Oncoimmunology 2012 Aug;1(5):593-599

National Center for Tumor Diseases, Department of Medical Oncology/Internal Medicine VI; University Hospital; Heidelberg, Germany.

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August 2012

Automatic tumor-stroma separation in fluorescence TMAs enables the quantitative high-throughput analysis of multiple cancer biomarkers.

PLoS One 2011 2;6(12):e28048. Epub 2011 Dec 2.

Institute of Medical Biometry and Informatics, University Hospital Heidelberg, Heidelberg, Germany.

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July 2012

A comparison of dacron versus Flocked nylon swabs for anal cytology specimen collection.

Acta Cytol 2011 22;55(4):364-7. Epub 2011 Jul 22.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20852, USA.

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September 2011

Robust gridding of TMAs after whole-slide imaging using template matching.

Cytometry A 2010 Dec;77(12):1169-76

Institute of Medical Biometry and Informatics, University Hospital Heidelberg, Heidelberg, Germany.

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December 2010

Impaired skin regeneration and remodeling after cutaneous injury and chemically induced hyperplasia in taps-transgenic mice.

J Invest Dermatol 2010 Jul 18;130(7):1922-30. Epub 2010 Mar 18.

Division of Signal Transduction and Growth Control (A100), DKFZ-ZMBH Alliance, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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July 2010

A virtual microscopy system to scan, evaluate and archive biomarker enhanced cervical cytology slides.

Cell Oncol 2010 ;32(1-2):109-19

Institute of Medical Biometry and Informatics, Section Medical Informatics, University Hospital Heidelberg, Heidelberg, Germany.

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June 2010