Bodo Melnik

Bodo Melnik

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Bodo Melnik

Bodo Melnik

Publications by authors named "Bodo Melnik"

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64Publications

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Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris.

Exp Dermatol 2018 Dec 17;27(12):1344-1351. Epub 2018 Oct 17.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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December 2018

Acne vulgaris: The metabolic syndrome of the pilosebaceous follicle.

Authors:
Bodo C Melnik

Clin Dermatol 2018 Jan - Feb;36(1):29-40. Epub 2017 Sep 8.

Department of Dermatology, Environmental Medicine and Health Theory, Faculty of Human Sciences, University of Osnabrück, Osnabrück, Germany. Electronic address:

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August 2018

Activated mTORC1 signaling: The common driving force of type 2 diabetes and hidradenitis suppurativa.

J Am Acad Dermatol 2018 05;78(5):e121

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Germany.

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May 2018

The Magnitude of mTORC1 Signalling May Predict the Response to Isotretinoin Treatment in Patients with Hidradenitis Suppurativa.

Dermatology 2017 20;233(5):399-400. Epub 2017 Dec 20.

Dermatology Unit, University of Naples Federico II, Naples, Italy.

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April 2018

Activation of mechanistic target of rapamycin complex 1: the common link between rheumatoid arthritis and diabetes mellitus.

Rheumatology (Oxford) 2018 Mar 7. Epub 2018 Mar 7.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Germany.

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March 2018

Overexpression of p53 explains isotretinoin's teratogenicity.

Authors:
Bodo C Melnik

Exp Dermatol 2018 01 7;27(1):91-93. Epub 2017 Nov 7.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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January 2018

p53: key conductor of all anti-acne therapies.

Authors:
Bodo C Melnik

J Transl Med 2017 09 19;15(1):195. Epub 2017 Sep 19.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Am Finkenhügel 7a, 49076, Osnabrück, Germany.

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September 2017

Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer.

Authors:
Bodo C Melnik

Nutr Metab (Lond) 2017 15;14:55. Epub 2017 Aug 15.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Am Finkenhügel 7a, D-49076 Osnabrück, Germany.

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August 2017

MicroRNAs: Milk's epigenetic regulators.

Best Pract Res Clin Endocrinol Metab 2017 08 20;31(4):427-442. Epub 2017 Oct 20.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.

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August 2017

Olumacostat Glasaretil, a Promising Topical Sebum-Suppressing Agent that Affects All Major Pathogenic Factors of Acne Vulgaris.

Authors:
Bodo C Melnik

J Invest Dermatol 2017 07;137(7):1405-1408

Department of Dermatology, Environmental Medicine, Health Theory, Faculty of Human Sciences, University of Osnabrück, Osnabrück, Germany. Electronic address:

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July 2017

The TRAIL to acne pathogenesis: let's focus on death pathways.

Authors:
Bodo C Melnik

Exp Dermatol 2017 03 9;26(3):270-272. Epub 2016 Dec 9.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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March 2017

Milk's Role as an Epigenetic Regulator in Health and Disease.

Diseases 2017 Mar 15;5(1). Epub 2017 Mar 15.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, University of Regensburg, Franz-Josef-Strauß-Allee 11, D-93053 Regensburg, Germany.

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March 2017

Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity.

Authors:
Bodo C Melnik

Acta Derm Venereol 2017 Feb;97(2):173-181

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, DE-49076 Osnabrück, Germany.

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February 2017

Pro-inflammatory sebocyte growth and survival signalling in acne vulgaris are reversed by pro-apoptotic isotretinoin signalling.

Authors:
Bodo C Melnik

Exp Dermatol 2016 09;25(9):676-7

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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September 2016

Milk: An epigenetic inducer of FoxP3 expression.

J Allergy Clin Immunol 2016 09 12;138(3):937-938. Epub 2016 Jul 12.

Institute for Clinical Chemistry and Laboratory Medicine, University Clinics of Regensburg, Regensburg, Germany.

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September 2016

Milk miRNAs: simple nutrients or systemic functional regulators?

Nutr Metab (Lond) 2016 21;13:42. Epub 2016 Jun 21.

Institute of Clinical Chemistry and Laboratory Medicine, University Clinics of Regensburg, Regensburg, Germany.

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June 2016

Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation.

Clin Transl Allergy 2016 12;6:18. Epub 2016 May 12.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, University of Regensburg, Josef-Strauss-Allee 11, 93053 Regensburg, Germany.

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May 2016

Is sebocyte-derived leptin the missing link between hyperseborrhea, ductal hypoxia, inflammation and comedogenesis in acne vulgaris?

Authors:
Bodo C Melnik

Exp Dermatol 2016 Mar 10;25(3):181-2. Epub 2016 Feb 10.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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March 2016

Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research.

Authors:
Bodo C Melnik

Acta Derm Venereol 2016 Feb;96(2):147-56

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, DE-49076 Osnabrück, Germany.

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February 2016

Western diet-induced imbalances of FoxO1 and mTORC1 signalling promote the sebofollicular inflammasomopathy acne vulgaris.

Authors:
Bodo C Melnik

Exp Dermatol 2016 Feb 12;25(2):103-4. Epub 2016 Jan 12.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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February 2016

Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases.

Authors:
Bodo C Melnik

J Transl Med 2015 Dec 21;13:385. Epub 2015 Dec 21.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, 49090, Osnabrück, Germany.

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December 2015

The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus.

Authors:
Bodo C Melnik

Curr Diabetes Rev 2015 ;11(1):46-62

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabruck, Sedanstraße 115, D-49090 Osnabrück, Germany.

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November 2015

Linking diet to acne metabolomics, inflammation, and comedogenesis: an update.

Authors:
Bodo C Melnik

Clin Cosmet Investig Dermatol 2015 15;8:371-88. Epub 2015 Jul 15.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Germany.

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July 2015

Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation.

Authors:
Bodo C Melnik

Int J Mol Sci 2015 Jul 27;16(8):17048-87. Epub 2015 Jul 27.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück D-49090, Germany.

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July 2015

MiR-21: an environmental driver of malignant melanoma?

Authors:
Bodo C Melnik

J Transl Med 2015 Jun 27;13:202. Epub 2015 Jun 27.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, 49090, Osnabrück, Germany.

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June 2015

The potential role of impaired Notch signalling in atopic dermatitis.

Authors:
Bodo C Melnik

Acta Derm Venereol 2015 Jan;95(1):5-11

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, DE-49076 Osnabrück, Germany.

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January 2015

Milk consumption during pregnancy increases birth weight, a risk factor for the development of diseases of civilization.

J Transl Med 2015 Jan 16;13:13. Epub 2015 Jan 16.

Institute of Clinical Chemistry and Laboratory Medicine, University Clinics of Regensburg, Regensburg, Germany.

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January 2015

Endoplasmic reticulum stress: key promoter of rosacea pathogenesis.

Authors:
Bodo C Melnik

Exp Dermatol 2014 Dec 7;23(12):868-73. Epub 2014 Oct 7.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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December 2014

Does therapeutic intervention in atopic dermatitis normalize epidermal Notch deficiency?

Authors:
Bodo C Melnik

Exp Dermatol 2014 Oct 16;23(10):696-700. Epub 2014 Jul 16.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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October 2014

The potential mechanistic link between allergy and obesity development and infant formula feeding.

Authors:
Bodo C Melnik

Allergy Asthma Clin Immunol 2014 22;10(1):37. Epub 2014 Jul 22.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, DE-49090 Osnabrück, Germany.

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July 2014

Adipogenic and insulin resistance- promoting effects of milk consumption.

Mol Nutr Food Res 2014 Jun;58(6):1166-7

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Germany.

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June 2014

The P450 system and mTORC1 signalling in acne.

Authors:
Bodo C Melnik

Exp Dermatol 2014 May;23(5):318-9

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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May 2014

Milk: an exosomal microRNA transmitter promoting thymic regulatory T cell maturation preventing the development of atopy?

J Transl Med 2014 Feb 12;12:43. Epub 2014 Feb 12.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, D-49090 Osnabrück, Germany.

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February 2014

Acne: risk indicator for increased body mass index and insulin resistance.

Acta Derm Venereol 2013 Nov;93(6):644-9

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, DE-49076 Osnabrück, Germany.

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November 2013

Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth.

Nutr J 2013 Jul 25;12:103. Epub 2013 Jul 25.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, D-49090, Osnabrück, Germany.

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July 2013

Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne.

Exp Dermatol 2013 May;22(5):311-5

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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May 2013

Impaired Notch-MKP-1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology.

Exp Dermatol 2013 Mar;22(3):172-7

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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March 2013

Excessive Leucine-mTORC1-Signalling of Cow Milk-Based Infant Formula: The Missing Link to Understand Early Childhood Obesity.

Authors:
Bodo C Melnik

J Obes 2012 19;2012:197653. Epub 2012 Mar 19.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, 49090 Osnabrück, Germany.

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August 2012

The impact of cow's milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer.

Nutr Metab (Lond) 2012 Aug 14;9(1):74. Epub 2012 Aug 14.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, Osnabrück, D-49090, Germany.

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August 2012

Diet in acne: further evidence for the role of nutrient signalling in acne pathogenesis.

Authors:
Bodo C Melnik

Acta Derm Venereol 2012 May;92(3):228-31

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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May 2012

Leucine signaling in the pathogenesis of type 2 diabetes and obesity.

Authors:
Bodo C Melnik

World J Diabetes 2012 Mar;3(3):38-53

Bodo C Melnik, Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, D-49090 Osnabrück, Germany.

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March 2012

Dietary intervention in acne: Attenuation of increased mTORC1 signaling promoted by Western diet.

Authors:
Bodo Melnik

Dermatoendocrinol 2012 Jan;4(1):20-32

Department of Dermatology; Environmental Medicine and Health Theory; University of Osnabrück; Osnabrück, Germany.

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January 2012

Isotretinoin and FoxO1: A scientific hypothesis.

Authors:
Bodo C Melnik

Dermatoendocrinol 2011 Jul 1;3(3):141-65. Epub 2011 Jul 1.

Department of Dermatology; Environmental Medicine and Health Theory; University of Osnabrück; Osnabrück, Germany.

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July 2011

Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization: lessons learnt from laron syndrome.

Nutr Metab (Lond) 2011 Jun 24;8:41. Epub 2011 Jun 24.

Institute for Clinical Chemistry and Laboratory Medicine, University Clinic of Regensburg, Franz-Josef-Strauss-Allee 11, D-93053 Regensburg, Germany.

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June 2011

Milk signalling in the pathogenesis of type 2 diabetes.

Authors:
Bodo C Melnik

Med Hypotheses 2011 Apr 19;76(4):553-9. Epub 2011 Jan 19.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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April 2011

Evidence for acne-promoting effects of milk and other insulinotropic dairy products.

Authors:
Bodo C Melnik

Nestle Nutr Workshop Ser Pediatr Program 2011 16;67:131-45. Epub 2011 Feb 16.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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March 2011

Steroid-induced periorificial dermatitis in children--clinical features and response to azelaic acid.

Pediatr Dermatol 2010 Mar-Apr;27(2):137-42. Epub 2009 Oct 4.

Department of Dermatology, Venereology and Allergology, University of Essen, Essen, Germany.

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September 2010

Recommendations for tap water iontophoresis.

J Dtsch Dermatol Ges 2010 May 28;8(5):379-83. Epub 2009 Aug 28.

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May 2010

FoxO1 - the key for the pathogenesis and therapy of acne?

Authors:
Bodo C Melnik

J Dtsch Dermatol Ges 2010 Feb;8(2):105-14

Department of Dermatology, Enviromental Medicine and Health Theory, University of Osnabrück, Germany.

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February 2010

Permanent impairment of insulin resistance from pregnancy to adulthood: the primary basic risk factor of chronic Western diseases.

Authors:
Bodo C Melnik

Med Hypotheses 2009 Nov 9;73(5):670-81. Epub 2009 Jun 9.

Department of Dermatology, Environmental Medicine and Health Theory, Division of Human Sciences, University of Osnabrück, Sedanstrasse 115, D-49090 Osnabrück, Germany.

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November 2009

Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris.

Exp Dermatol 2009 Oct 25;18(10):833-41. Epub 2009 Aug 25.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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October 2009

Consumption of milk as a vital factor in growth development.

Authors:
Bodo Melnik

Dtsch Arztebl Int 2009 Oct 2;106(40):656; author reply 656. Epub 2009 Oct 2.

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October 2009

Anti-acne agents attenuate FGFR2 signal transduction in acne.

J Invest Dermatol 2009 Aug 19;129(8):1868-77. Epub 2009 Feb 19.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

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August 2009

Milk--the promoter of chronic Western diseases.

Authors:
Bodo C Melnik

Med Hypotheses 2009 Jun 15;72(6):631-9. Epub 2009 Feb 15.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, D-49090 Osnabrück, Germany.

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June 2009

Androgen abuse in the community.

Authors:
Bodo C Melnik

Curr Opin Endocrinol Diabetes Obes 2009 Jun;16(3):218-23

Department of Dermatology, Environmental Medicine and Health Theory, Division of Human Sciences, University of Osnabrück, Germany.

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June 2009

Role of FGFR2-signaling in the pathogenesis of acne.

Authors:
Bodo C Melnik

Dermatoendocrinol 2009 May;1(3):141-56

Department of Dermatology; Environmental Medicine and Health Theory; University of Osnabrück; Germany.

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May 2009

Milk consumption: aggravating factor of acne and promoter of chronic diseases of Western societies.

Authors:
Bodo Melnik

J Dtsch Dermatol Ges 2009 Apr 20;7(4):364-70. Epub 2008 Feb 20.

Department of Dermatology, Environmental Medicine, and Health Theory, University of Osnabrück, Germany.

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April 2009

FGFR2 signaling and the pathogenesis of acne.

J Dtsch Dermatol Ges 2008 Sep;6(9):721-8

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Germany.

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September 2008

Abuse of anabolic-androgenic steroids and bodybuilding acne: an underestimated health problem.

J Dtsch Dermatol Ges 2007 Feb;5(2):110-7

Department of Dermatology, Environmental Medicine and Health Science, Division of Human Sciences, University of OsnabrYck, Germany.

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February 2007

[Disturbances of antimicrobial lipids in atopic dermatitis].

Authors:
Bodo Melnik

J Dtsch Dermatol Ges 2006 Feb;4(2):114-23

Dermatologie, Umweltmedizin und Gesundheitstheorie, Fachbereich Humanwissenshaften, Universität of Osnabrück, Germany.

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February 2006

Lipid composition of outer stratum corneum in hereditary palmoplantar keratodermas.

Dermatology 2003 ;206(2):131-5

Department of Dermatology, TOMESA Clinics, Bad Salzschlirf, Germany.

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June 2003