Ayalew Tefferi

Ayalew Tefferi

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Ayalew Tefferi

Publications by authors named "Ayalew Tefferi"

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Atypical Phenotype and Treatment Response Pattern in a Patient with FIP1L1-PDGFRα Mutation.

Acta Haematol 2018 5;140(2):67-70. Epub 2018 Sep 5.

Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1159/000492485DOI Listing
June 2019

Mutations and prognosis in myeloproliferative neoplasms.

Leuk Lymphoma 2019 May 14;60(5):1112-1113. Epub 2018 Nov 14.

a Division of Hematology, Department of Internal Medicine , Mayo Clinic , Rochester , MN , USA.

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http://dx.doi.org/10.1080/10428194.2018.1537490DOI Listing
May 2019

Cytogenetic clonal evolution in myeloproliferative neoplasms: contexts and prognostic impact among 648 patients with serial bone marrow biopsies.

Leukemia 2019 May 1. Epub 2019 May 1.

Divisions of Laboratory Genetics and Genomics, Departments of Internal Medicine and Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41375-019-0453-5DOI Listing
May 2019

Refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis: "2019 Update on Diagnosis, Risk-stratification, and Management".

Am J Hematol 2019 Apr 24;94(4):475-488. Epub 2019 Jan 24.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/ajh.25397
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http://dx.doi.org/10.1002/ajh.25397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408294PMC
April 2019

Calculator-free point-of-care prognostication in myelodysplastic syndromes.

Am J Hematol 2019 Apr 24;94(4):E99-E101. Epub 2019 Jan 24.

Divisions of Hematology, Departments of Internal and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/ajh.25400
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http://dx.doi.org/10.1002/ajh.25400DOI Listing
April 2019

Determinants of long-term outcome in type 1 calreticulin-mutated myelofibrosis.

Leukemia 2019 03 12;33(3):780-785. Epub 2018 Oct 12.

Divisions of Hematology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41375-018-0283-xDOI Listing
March 2019

World Health Organization class-independent risk categorization in mastocytosis.

Blood Cancer J 2019 03 4;9(3):29. Epub 2019 Mar 4.

Divisions of Hematology, Departments of Internal Medicine and Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41408-019-0189-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399221PMC
March 2019

Smoldering mastocytosis: Survival comparisons with indolent and aggressive mastocytosis.

Am J Hematol 2019 Jan 9;94(1):E1-E2. Epub 2018 Nov 9.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/ajh.25302
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http://dx.doi.org/10.1002/ajh.25302DOI Listing
January 2019

Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.

Am J Hematol 2019 Jan 9;94(1):133-143. Epub 2018 Nov 9.

Research Foundation, Papa Giovanni XXIII Hospital, Bergamo, Italy.

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http://dx.doi.org/10.1002/ajh.25303DOI Listing
January 2019

Monocytosis is a powerful and independent predictor of inferior survival in primary myelofibrosis.

Br J Haematol 2018 12 19;183(5):835-838. Epub 2017 Dec 19.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1111/bjh.15061DOI Listing
December 2018

Primary myelofibrosis: 2019 update on diagnosis, risk-stratification and management.

Authors:
Ayalew Tefferi

Am J Hematol 2018 12 26;93(12):1551-1560. Epub 2018 Oct 26.

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/ajh.25230
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http://dx.doi.org/10.1002/ajh.25230DOI Listing
December 2018

Practice-relevant demarcation of systemic mastocytosis associated with another hematologic neoplasm.

Am J Hematol 2018 12 17;93(12):E383-E386. Epub 2018 Oct 17.

Divisions of Hematology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25269DOI Listing
December 2018

Myeloproliferative neoplasms in the young: Mayo Clinic experience with 361 patients age 40 years or younger.

Am J Hematol 2018 12 27;93(12):1474-1484. Epub 2018 Sep 27.

Divisions of Hematology, Departments of Internal and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25270DOI Listing
December 2018

Mutations and karyotype predict treatment response in myelodysplastic syndromes.

Am J Hematol 2018 11 30;93(11):1420-1426. Epub 2018 Sep 30.

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25267DOI Listing
November 2018

Genetic predictors of response to specific drugs in primary myelofibrosis.

Blood Cancer J 2018 11 19;8(12):120. Epub 2018 Nov 19.

Divisions of Hematology, Departments of Internal Medicine and Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41408-018-0158-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242902PMC
November 2018

MPL-mutated essential thrombocythemia: a morphologic reappraisal.

Blood Cancer J 2018 11 20;8(12):121. Epub 2018 Nov 20.

Division of Hematology, Departments of Internal and Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41408-018-0159-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246562PMC
November 2018

U2AF1 mutation types in primary myelofibrosis: phenotypic and prognostic distinctions.

Leukemia 2018 10 27;32(10):2274-2278. Epub 2018 Feb 27.

Division of Hematology, Departments of Medicine and Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41375-018-0078-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170397PMC
October 2018

Upfront low-dose ponatinib (15 mg/day) for multi-TKI resistant chronic myeloid leukemia.

Authors:
Ayalew Tefferi

Hematol Oncol 2018 Oct 14;36(4):718-720. Epub 2018 Jun 14.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1002/hon.2517DOI Listing
October 2018

Early thrombotic events and preemptive systemic anticoagulation following splenectomy for myelofibrosis.

Am J Hematol 2018 09 31;93(9):E235-E238. Epub 2018 Aug 31.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25203DOI Listing
September 2018

Blast-phase chronic myelomonocytic leukemia: more than just semantics.

Leukemia 2018 09 7;32(9):2093-2094. Epub 2018 Aug 7.

MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41375-018-0228-4DOI Listing
September 2018

JAK2 exon 12 mutated polycythemia vera: Mayo-Careggi MPN Alliance study of 33 consecutive cases and comparison with JAK2V617F mutated disease.

Am J Hematol 2018 08;93(4):E93-E96

Department of Experimental and Clinical Medicine, CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy.

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http://doi.wiley.com/10.1002/ajh.25017
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http://dx.doi.org/10.1002/ajh.25017DOI Listing
August 2018

A retrospective survey of exposure history to chemotherapy or radiotherapy in 940 consecutive patients with primary myelofibrosis.

Am J Hematol 2018 08 27;93(4):E103-E107. Epub 2018 Jan 27.

Divisions of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/ajh.25037
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http://dx.doi.org/10.1002/ajh.25037DOI Listing
August 2018

Chronic neutrophilic leukemia: 2018 update on diagnosis, molecular genetics and management.

Am J Hematol 2018 08;93(4):578-587

Department of Internal Medicine, Division of Hematology, Mayo Clinic College of Medicine, 200 First St. SW, Rochester, Minnesota, 55905.

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http://dx.doi.org/10.1002/ajh.24983DOI Listing
August 2018

How I treat myelofibrosis after failure of JAK inhibitors.

Blood 2018 08 4;132(5):492-500. Epub 2018 Jun 4.

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1182/blood-2018-02-785923DOI Listing
August 2018

FGFR1 rearranged hematological neoplasms - molecularly defined and clinically heterogeneous.

Leuk Lymphoma 2018 07 31;59(7):1520-1522. Epub 2018 Jan 31.

a Department of Internal Medicine , Mayo Clinic , MN , USA.

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http://dx.doi.org/10.1080/10428194.2018.1429607DOI Listing
July 2018

GIPSS: genetically inspired prognostic scoring system for primary myelofibrosis.

Leukemia 2018 07 23;32(7):1631-1642. Epub 2018 Mar 23.

Department of Experimental and Clinical Medicine, CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1038/s41375-018-0107-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035151PMC
July 2018

The impact of sex on disease phenotype and prognostic thresholds of anemia in myelodysplastic syndromes.

Am J Hematol 2018 07 6;93(7):E164-E167. Epub 2018 May 6.

Divisions of Hematology, Departments of Internal and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25114DOI Listing
July 2018

Myelofibrosis Treatment Algorithm 2018.

Blood Cancer J 2018 07 31;8(8):72. Epub 2018 Jul 31.

Department of Experimental and Clinical Medicine, CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1038/s41408-018-0109-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068139PMC
July 2018

U2AF1 mutation variants in myelodysplastic syndromes and their clinical correlates.

Am J Hematol 2018 Jun 6;93(6):E146-E148. Epub 2018 Apr 6.

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25084DOI Listing
June 2018

MIPSS70+ Version 2.0: Mutation and Karyotype-Enhanced International Prognostic Scoring System for Primary Myelofibrosis.

J Clin Oncol 2018 06 30;36(17):1769-1770. Epub 2018 Apr 30.

Ayalew Tefferi, Mayo Clinic, Rochester, MN; Paola Guglielmelli, University of Florence, Florence, Italy; Terra L. Lasho, Naseema Gangat, Rhett P. Ketterling, and Animesh Pardanani, Mayo Clinic, Rochester, MN; and Alessandro M. Vannucchi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1200/JCO.2018.78.9867DOI Listing
June 2018

Chronic myelomonocytic leukemia: 2018 update on diagnosis, risk stratification and management.

Am J Hematol 2018 06;93(6):824-840

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/ajh.25104
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http://dx.doi.org/10.1002/ajh.25104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995129PMC
June 2018

Validation of the WHO-defined 20% circulating blasts threshold for diagnosis of leukemic transformation in primary myelofibrosis.

Blood Cancer J 2018 06 11;8(6):57. Epub 2018 Jun 11.

Department of Internal Medicine and Laboratory Medicine, Division of Hematology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41408-018-0095-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996023PMC
June 2018

Ruxolitinib as first-line treatment in secondary hemophagocytic lymphohistiocytosis: A second experience.

Am J Hematol 2018 05 24;93(5):E123-E125. Epub 2018 Feb 24.

Division of Hematology, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/ajh.25063
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http://dx.doi.org/10.1002/ajh.25063DOI Listing
May 2018

Mayo CALR mutation type classification guide using alpha helix propensity.

Am J Hematol 2018 05 24;93(5):E128-E129. Epub 2018 Feb 24.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.25065DOI Listing
May 2018

Prevention of liver cancer with new curative hepatitis C antivirals: Real-world challenges.

Cancer 2018 04 27;124(8):1647-1649. Epub 2018 Feb 27.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/cncr.31291DOI Listing
April 2018

Driver mutations and prognosis in primary myelofibrosis: Mayo-Careggi MPN alliance study of 1,095 patients.

Am J Hematol 2018 03 18;93(3):348-355. Epub 2017 Dec 18.

Department of Experimental and Clinical Medicine, CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/ajh.24978DOI Listing
March 2018

Polycythemia vera and essential thrombocythemia: algorithmic approach.

Curr Opin Hematol 2018 03;25(2):112-119

Department of Internal Medicine, Divisions of Hematology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000402DOI Listing
March 2018

Driver mutations in primary myelofibrosis and their implications.

Curr Opin Hematol 2018 03;25(2):129-135

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000406DOI Listing
March 2018

Ruxolitinib as first-line treatment in secondary hemophagocytic lymphohistiocytosis: A single patient experience.

Am J Hematol 2018 Feb 4;93(2):E47-E49. Epub 2017 Dec 4.

Division of Hematology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.24971DOI Listing
February 2018

MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis.

J Clin Oncol 2018 02 9;36(4):310-318. Epub 2017 Dec 9.

Paola Guglielmelli, Giada Rotunno, Carmela Mannarelli, Annalisa Pacilli, Francesco Mannelli, and Alessandro M. Vannucchi, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence; Elisa Rumi, Vittorio Rosti, Giovanni Barosi, and Mario Cazzola, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo; Elisa Rumi and Mario Cazzola, University of Pavia, Pavia; Alessandro Rambaldi, University of Milan, Milan; Alessandro Rambaldi and Tiziano Barbui, Azienda Socio sanitaria Territoriale Papa Giovanni XXIII, Bergamo; Francesco Passamonti, University of Insubria, Varese, Italy; and Terra L. Lasho, Mythri Mudireddy, Maura Nicolosi, Animesh Pardanani, Curtis A. Hanson, Rhett P. Ketterling, Naseema Gangat, and Ayalew Tefferi, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2017.76.4886DOI Listing
February 2018

Chronic neutrophilic leukemia: new science and new diagnostic criteria.

Blood Cancer J 2018 02 13;8(2):19. Epub 2018 Feb 13.

Department of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/s41408-018-0049-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811432PMC
February 2018

Revisiting the need for bone marrow examination in chronic myeloid leukemia.

Am J Hematol 2018 01 3;93(1):5-7. Epub 2017 Nov 3.

Divisions of Laboratory Genetics and Genomics, Departments of Internal and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.24942DOI Listing
January 2018

Lenalidomide therapy in patients with myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T).

Am J Hematol 2018 01 10;93(1):E27-E30. Epub 2017 Nov 10.

Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1002/ajh.24952DOI Listing
January 2018

Essential thrombocythemia treatment algorithm 2018.

Blood Cancer J 2018 01 10;8(1). Epub 2018 Jan 10.

Research Foundation, Papa Giovanni XXIII Hospital, Bergamo, Italy.

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http://dx.doi.org/10.1038/s41408-017-0041-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802626PMC
January 2018

Polycythemia vera treatment algorithm 2018.

Blood Cancer J 2018 01 10;8(1). Epub 2018 Jan 10.

Research Foundation, Papa Giovanni XXIII Hospital, Bergamo, Italy.

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http://dx.doi.org/10.1038/s41408-017-0042-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802495PMC
January 2018

Targeted next-generation sequencing in myelodysplastic syndromes and prognostic interaction between mutations and IPSS-R.

Am J Hematol 2017 Dec 20;92(12):1311-1317. Epub 2017 Oct 20.

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.24901DOI Listing
December 2017

Anemia in myelofibrosis-prevalence, the U2AF1 connection, new treatments.

Authors:
Ayalew Tefferi

Blood Cancer J 2017 12 15;7(12):648. Epub 2017 Dec 15.

Division of Hematology, Department of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1038/s41408-017-0032-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802449PMC
December 2017

Marked elevation of serum lactate dehydrogenase in primary myelofibrosis: clinical and prognostic correlates.

Blood Cancer J 2017 12 18;7(12):657. Epub 2017 Dec 18.

Division of Hematology, Department of Internal and Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

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http://www.nature.com/articles/s41408-017-0024-9
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http://dx.doi.org/10.1038/s41408-017-0024-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802557PMC
December 2017

Risk factors and a prognostic model for postsplenectomy survival in myelofibrosis.

Am J Hematol 2017 Nov 24;92(11):1187-1192. Epub 2017 Aug 24.

Department of, Surgery, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajh.24881DOI Listing
November 2017

Gender and survival in essential thrombocythemia: A two-center study of 1,494 patients.

Am J Hematol 2017 Nov 28;92(11):1193-1197. Epub 2017 Aug 28.

Department of Experimental and Clinical Medicine, CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/ajh.24882DOI Listing
November 2017

Myeloproliferative Neoplasms.

N Engl J Med 2017 08;377(9):894-5

Mayo Clinic, Rochester, MN

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http://www.nejm.org/doi/10.1056/NEJMc1708485
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http://dx.doi.org/10.1056/NEJMc1708485DOI Listing
August 2017