Aya Kuchiba

Aya Kuchiba

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Aya Kuchiba

Publications by authors named "Aya Kuchiba"

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Single-arm, multicentre, phase II trial of nivolumab for unresectable or recurrent thymic carcinoma: PRIMER study.

Eur J Cancer 2019 May 13;113:78-86. Epub 2019 Apr 13.

Department of Thoracic Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1016/j.ejca.2019.03.012DOI Listing
May 2019

Plasma C-peptide and glycated albumin and subsequent risk of cancer: From a large prospective case-cohort study in Japan.

Int J Cancer 2019 02 30;144(4):718-729. Epub 2018 Oct 30.

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

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http://dx.doi.org/10.1002/ijc.31847DOI Listing
February 2019

Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models.

Eur J Hum Genet 2019 01 10;27(1):140-149. Epub 2018 Sep 10.

Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

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http://www.nature.com/articles/s41431-018-0251-y
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http://dx.doi.org/10.1038/s41431-018-0251-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303260PMC
January 2019

Decomposition of the population attributable fraction for two exposures.

Ann Epidemiol 2018 05 2;28(5):331-334.e1. Epub 2018 Mar 2.

Biostatistics Division, Center for Research Administration and Support, National Cancer Center, Tokyo, Japan; Division of Biostatistical Research, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.annepidem.2018.02.012DOI Listing
May 2018

A Prospective Study of Smoking and Risk of Synchronous Colorectal Cancers.

Am J Gastroenterol 2017 03 24;112(3):493-501. Epub 2017 Jan 24.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ajg.2016.589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342916PMC
March 2017

Accuracy of Death Certificates and Assessment of Factors for Misclassification of Underlying Cause of Death.

J Epidemiol 2016 5;26(4):191-8. Epub 2015 Dec 5.

Department of Medical Informatics, Center for Information, Jichi Medical University.

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http://dx.doi.org/10.2188/jea.JE20150010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808686PMC
August 2016

Statistical methods for studying disease subtype heterogeneity.

Stat Med 2016 Feb 1;35(5):782-800. Epub 2015 Dec 1.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, U.S.A.

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http://dx.doi.org/10.1002/sim.6793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728021PMC
February 2016

A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells.

Sci Rep 2016 Jan 27;6:19772. Epub 2016 Jan 27.

Department of Clinical Pharmacology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1038/srep19772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728441PMC
January 2016

Tumor LINE-1 methylation level and microsatellite instability in relation to colorectal cancer prognosis.

J Natl Cancer Inst 2014 Sep 4;106(9). Epub 2014 Sep 4.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (KI, MY, RN, PL, ZRQ, AK, SAK, KM, YS, JAM, CSF, SO); Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD (KI, CCH); Department of Nutrition, Harvard School of Public Health, Boston, MA (RN, AK, KW); Gastrointestinal Research Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK (PL); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA (SJ, XZ, EC, ATC, CSF); Department of Dermatology, The Warren Alpert Medical School of Brown University, Province, RI (EC); Division of Gastroenterology, Massachusetts General Hospital, Boston, MA (ATC); Department of Epidemiology, Harvard School of Public Health, Boston, MA (SO); Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA (SO).

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http://dx.doi.org/10.1093/jnci/dju195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161997PMC
September 2014

Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD).

Sci Transl Med 2014 Apr;6(233):233re2

Department of Medicine and Case Comprehensive Cancer Center, Case Western Reserve University and University Hospitals Case Medical Center, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1126/scitranslmed.3008481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030641PMC
April 2014

Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations.

J Natl Cancer Inst 2013 Dec 7;105(24):1852-61. Epub 2013 Dec 7.

Affiliations of authors: Division of Cancer Epidemiology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD (HN); Channing Division of Network Medicine, Department of Medicine (HN, DJH, ELG, CSF, ATC) and Department of Epidemiology (DJH, PK, ELG, SO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Center for Molecular Oncologic Pathology (TM, YI, AK, MY, SO), Department of Medical Oncology (TM, MS, YI, AK, MY, CSF, SO, MLF), and Department of Biostatistics and Computational Biology (LW), Dana-Farber Cancer Institute, Boston, MA; Department of Epidemiology (DJH, ELG, SO) and Department of Nutrition, Harvard School of Public Health, Boston, MA (DJH, ELG); Broad Institute, Program in Medical and Population Genetics, Cambridge, MA (MLF); Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (ATC).

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http://dx.doi.org/10.1093/jnci/djt331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866156PMC
December 2013

Prognostic significance of MTOR pathway component expression in neuroendocrine tumors.

J Clin Oncol 2013 Sep 26;31(27):3418-25. Epub 2013 Aug 26.

Zhi Rong Qian, Monica Ter-Minassian, Jennifer A. Chan, Yu Imamura, Susanne M. Hooshmand, Aya Kuchiba, Teppei Morikawa, Lauren K. Brais, Anastassia Daskalova, Rachel Heafield, Charles S. Fuchs, Shuji Ogino, Matthew H. Kulke, Dana-Farber Cancer Institute and Harvard Medical School; Monica Ter-Minassian, Xihong Lin, David C. Christiani, Shuji Ogino, Harvard School of Public Health; David C. Christiani, Massachusetts General Hospital, Harvard Medical School; Charles S. Fuchs, Shuji Ogino, Brigham and Women's Hospital, Boston, MA.

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http://jco.ascopubs.org/content/31/27/3418.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2012.46.6946
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http://dx.doi.org/10.1200/JCO.2012.46.6946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770868PMC
September 2013

Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication.

J Natl Cancer Inst 2013 Aug 22;105(15):1151-6. Epub 2013 Jul 22.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1093/jnci/djt173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735463PMC
August 2013

A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification.

Am J Epidemiol 2013 Jul 20;178(1):84-100. Epub 2013 Jun 20.

Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Epidemiology, Harvard School of Public Health, 450 Brookline Avenue, Room JF-215C, Boston, MA 02215, USA.

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http://dx.doi.org/10.1093/aje/kws431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698990PMC
July 2013

Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer.

Cancer Epidemiol Biomarkers Prev 2013 Jun 29;22(6):1142-52. Epub 2013 Apr 29.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681847PMC
June 2013

Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.

Eur J Cancer 2012 Dec 26;48(18):3405-13. Epub 2012 Jul 26.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, United States.

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http://dx.doi.org/10.1016/j.ejca.2012.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613860PMC
December 2012

Tumor TP53 expression status, body mass index and prognosis in colorectal cancer.

Int J Cancer 2012 Sep 19;131(5):1169-78. Epub 2011 Nov 19.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, and Department of Medicine Brigham and Women's Hospital, Boston, MA 02215, USA.

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http://doi.wiley.com/10.1002/ijc.26495
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http://dx.doi.org/10.1002/ijc.26495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288809PMC
September 2012

Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.

Clin Cancer Res 2012 Sep 2;18(17):4753-63. Epub 2012 Jul 2.

Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 450 Brookline Ave., Room JF-215C, Boston, MA 02215, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-3210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624899PMC
September 2012

Postmenopausal hormone therapy is associated with a reduced risk of colorectal cancer lacking CDKN1A expression.

Cancer Res 2012 Jun 17;72(12):3020-8. Epub 2012 Apr 17.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377852PMC
June 2012

Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review.

Clin Cancer Res 2012 Apr 22;18(8):2257-68. Epub 2012 Feb 22.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628835PMC
April 2012

Body mass index and risk of colorectal cancer according to fatty acid synthase expression in the nurses' health study.

J Natl Cancer Inst 2012 Mar 6;104(5):415-20. Epub 2012 Feb 6.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1093/jnci/djr542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295745PMC
March 2012

TGFBR2 and BAX mononucleotide tract mutations, microsatellite instability, and prognosis in 1072 colorectal cancers.

PLoS One 2011 20;6(9):e25062. Epub 2011 Sep 20.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025062PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176811PMC
February 2012

Mitochondrial haplogroups A and M7a confer a genetic risk for coronary atherosclerosis in the Japanese elderly: an autopsy study of 1,536 patients.

J Atheroscler Thromb 2011 19;18(2):166-75. Epub 2010 Nov 19.

Department of Pathology and Bioresource Center for Geriatric Research, Tokyo Metropolitan Geriatric Hospital, Itabashi, Tokyo, Japan.

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http://dx.doi.org/10.5551/jat.6742DOI Listing
June 2011

Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer.

JAMA 2011 Apr;305(16):1685-94

Department of Medical Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 450 Brookline Ave, Boston, MA 02215, USA.

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http://dx.doi.org/10.1001/jama.2011.513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087286PMC
April 2011

Contribution of the TP53, OGG1, CHRNA3, and HLA-DQA1 genes to the risk for lung squamous cell carcinoma.

J Thorac Oncol 2011 Apr;6(4):813-7

Biology Division, National Cancer Center Research Institute; †Division of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e3181ee80efDOI Listing
April 2011

STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers.

Clin Cancer Res 2011 Mar 10;17(6):1452-62. Epub 2011 Feb 10.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077111PMC
March 2011

Genome-wide germline analyses on cancer susceptibility and GeMDBJ database: Gastric cancer as an example.

Cancer Sci 2010 Jul 9;101(7):1582-9. Epub 2010 Apr 9.

Genetics Division, National Cancer Center Research Institute, Tokyo, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2010.01590.x
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http://dx.doi.org/10.1111/j.1349-7006.2010.01590.xDOI Listing
July 2010

Genome-wide association study of pancreatic cancer in Japanese population.

PLoS One 2010 Jul 29;5(7):e11824. Epub 2010 Jul 29.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, Department of Medical Genome Sciences, Graduate School of Frontier Scineces, the University of Tokyo, National Cancer Center Hospital, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011824PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912284PMC
July 2010

Contact lens wear is associated with decrease of meibomian glands.

Ophthalmology 2009 Mar 22;116(3):379-84. Epub 2009 Jan 22.

Itoh Clinic, Saitama, Japan.

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http://dx.doi.org/10.1016/j.ophtha.2008.10.012DOI Listing
March 2009

Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese.

Carcinogenesis 2009 Jan 12;30(1):65-70. Epub 2008 Nov 12.

Biology Division, National Cancer Center Research Institute, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1093/carcin/bgn257DOI Listing
January 2009

Association of KRAS polymorphisms with risk for lung adenocarcinoma accompanied by atypical adenomatous hyperplasias.

Carcinogenesis 2008 May 24;29(5):957-63. Epub 2008 Feb 24.

Biology Division, National Cancer Center Research Institute, Tokyo 1040045, Japan.

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http://dx.doi.org/10.1093/carcin/bgn048DOI Listing
May 2008

Polymorphisms in pro- and anti-inflammatory cytokine genes and susceptibility to atherosclerosis: a pathological study of 1503 consecutive autopsy cases.

Hum Mol Genet 2007 Mar 9;16(6):592-9. Epub 2007 Jan 9.

Department of Molecular Epidemiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1093/hmg/ddl483DOI Listing
March 2007

Optimum two-stage designs in case-control association studies using false discovery rate.

J Hum Genet 2006 27;51(12):1046-54. Epub 2006 Sep 27.

Department of Biostatistics/Epidemiology and Preventive Health Sciences, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1007/s10038-006-0057-6DOI Listing
February 2007

Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk.

Cancer Sci 2006 Aug 23;97(8):724-8. Epub 2006 Jun 23.

Biology Division, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045.

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http://doi.wiley.com/10.1111/j.1349-7006.2006.00240.x
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http://dx.doi.org/10.1111/j.1349-7006.2006.00240.xDOI Listing
August 2006