Publications by authors named "Axel Ullrich"

100Publications

Retraction Notice to: The Cancer-Associated FGFR4-G388R Polymorphism Enhances Pancreatic Insulin Secretion and Modifies the Risk of Diabetes.

Authors:
Shereen Ezzat Lei Zheng Jose C Florez Norbert Stefan Thomas Mayr Maw Maw Hliang Kathleen Jablonski Maegan Harden Alena Stanĉáková Markku Laakso Hans-Ulrich Haring Axel Ullrich Sylvia L Asa

Cell Metab 2020 10;32(4):691

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October 2020

Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach.

Authors:
Zhiguang Xiao Bianca Sperl Silvia Gärtner Tatiana Nedelko Elvira Stacher-Priehse Axel Ullrich Pjotr G Knyazev

Oncotarget 2019 Apr 2;10(26):2546-2560. Epub 2019 Apr 2.

Department of Molecular Biology, Max-Planck Institute of Biochemistry, Martinsried, Munich, 82152, Germany.

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April 2019

The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet.

Authors:
Stefan Z Lutz Anita M Hennige Andreas Peter Marketa Kovarova Charisis Totsikas Jürgen Machann Stefan M Kröber Bianca Sperl Erwin Schleicher Fritz Schick Martin Heni Axel Ullrich Hans-Ulrich Häring Norbert Stefan

J Clin Endocrinol Metab 2019 06;104(6):2041-2053

Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.

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June 2019

Discovery of N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors.

Authors:
István Szabadkai Robert Torka Rita Garamvölgyi Ferenc Baska Pál Gyulavári Sándor Boros Eszter Illyés Axel Choidas Axel Ullrich László Őrfi

J Med Chem 2018 Jul 9;61(14):6277-6292. Epub 2018 Jul 9.

Vichem Chemie Research Ltd. , Budapest 1022 , Hungary.

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July 2018

Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans.

Authors:
Stefan Z Lutz Mathias Falcenberg Fausto Machicao Andreas Peter Martin Kächele Elko Randrianarisoa Angela Lehn-Stefan Robert Wagner Jürgen Machann Fritz Schick Martin Heni Axel Ullrich Andreas Fritsche Norbert Stefan Hans-Ulrich Häring Harald Staiger Konstantinos Kantartzis

Sci Rep 2018 05 17;8(1):7745. Epub 2018 May 17.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany.

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May 2018

GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance.

Authors:
Christine Baumann Axel Ullrich Robert Torka

Mol Oncol 2017 10 26;11(10):1430-1447. Epub 2017 Jul 26.

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany.

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October 2017

Sunitinib specifically augments glucose-induced insulin secretion.

Authors:
Stefan Z Lutz Axel Ullrich Hans-Ulrich Häring Susanne Ullrich Felicia Gerst

Cell Signal 2017 08 24;36:91-97. Epub 2017 Apr 24.

German Center for Diabetes Research (DZD e.V.), Germany; Institute for Diabetes Research and Metabolic Diseases IDM of the Helmholtz Center Munich at the Eberhard-Karls-University of Tübingen, Germany; University Hospital Tübingen, Internal Medicine IV, Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Otfried-Müller-Str. 10, 72076 Tübingen, Germany. Electronic address:

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August 2017

Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients.

Authors:
Zhiguang Xiao Silvia Gaertner Alicia Morresi-Hauf Rebecca Genzel Thomas Duell Axel Ullrich Pjotr G Knyazev

Neoplasia 2017 May 7;19(5):385-395. Epub 2017 Apr 7.

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18a, Martinsried, D-82152, Germany. Electronic address:

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May 2017

Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases.

Authors:
Ann-Katrin Sommer Adam Hermawan Frauke Martina Mickler Bojan Ljepoja Pjotr Knyazev Christoph Bräuchle Axel Ullrich Ernst Wagner Andreas Roidl

Oncotarget 2016 Aug;7(31):50461-50476

Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.

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August 2016

Membrane-proximal binding of STAT3 revealed by cancer-associated receptor variants.

Authors:
Vijay K Ulaganathan Axel Ullrich

Mol Cell Oncol 2016 May 24;3(3):e1145176. Epub 2016 Feb 24.

Max Planck Institute for Biochemistry, Department of Molecular Biology , Martinsried, Germany.

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May 2016

Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo.

Authors:
Julia Onken Robert Torka Sören Korsing Josefine Radke Irina Krementeskaia Melina Nieminen Xi Bai Axel Ullrich Frank Heppner Peter Vajkoczy

Oncotarget 2016 Mar;7(9):9876-89

Department of Neurosurgery, Charité, Berlin, Germany.

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March 2016

Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetes.

Authors:
Laura Simon-Szabó Márton Kokas Zoltán Greff Sándor Boros Péter Bánhegyi Lilián Zsákai Csaba Szántai-Kis Tibor Vantus József Mandl Gábor Bánhegyi István Vályi-Nagy László Őrfi Axel Ullrich Miklós Csala György Kéri

Bioorg Med Chem Lett 2016 Jan 28;26(2):424-428. Epub 2015 Nov 28.

MTA-SE Pathobiochemistry Research Group, Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, 1444 Budapest, Hungary; Vichem Chemie Research Ltd, 1022 Budapest, Hungary. Electronic address:

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January 2016

Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site.

Authors:
Vijay K Ulaganathan Bianca Sperl Ulf R Rapp Axel Ullrich

Nature 2015 Dec 16;528(7583):570-4. Epub 2015 Dec 16.

Max Planck Institute for Biochemistry, Department of Molecular Biology, Am Klopferspitz 18, 82152, Martinsried. Germany.

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December 2015

Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.

Authors:
Alexander Grabner Ansel P Amaral Karla Schramm Saurav Singh Alexis Sloan Christopher Yanucil Jihe Li Lina A Shehadeh Joshua M Hare Valentin David Aline Martin Alessia Fornoni Giovana Seno Di Marco Dominik Kentrup Stefan Reuter Anna B Mayer Hermann Pavenstädt Jörg Stypmann Christian Kuhn Susanne Hille Norbert Frey Maren Leifheit-Nestler Beatrice Richter Dieter Haffner Reimar Abraham Johannes Bange Bianca Sperl Axel Ullrich Marcus Brand Myles Wolf Christian Faul

Cell Metab 2015 Dec 1;22(6):1020-32. Epub 2015 Oct 1.

Katz Family Drug Discovery Center and Division of Nephrology and Hypertension, Department of Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, USA; Department of Cell Biology and Anatomy, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, USA. Electronic address:

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December 2015

Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell lines.

Authors:
Simone Gusenbauer Emanuele Zanucco Pjotr Knyazev Axel Ullrich

Mol Cancer 2015 Mar 4;14:54. Epub 2015 Mar 4.

Department of Molecular Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152, Martinsried, Germany.

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March 2015

Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells.

Authors:
Kinga Pénzes Christine Baumann István Szabadkai László Orfi György Kéri Axel Ullrich Robert Torka

Cancer Biol Ther 2014 ;15(11):1571-82

a Department of Molecular Biology; Max-Planck-Institute of Biochemistry ; Martinsried , Germany.

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August 2015

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status.

Authors:
Zhiguang Xiao Bianca Sperl Axel Ullrich Pjotr Knyazev

Oncotarget 2014 Dec;5(24):12877-90

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz, Martinsried, Germany.

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December 2014

PTK7 as a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients, and resistance to anthracycline drugs.

Authors:
Beyhan Ataseven Angela Gunesch Wolfgang Eiermann Ronald E Kates Bernhard Högel Pjotr Knyazev Axel Ullrich Nadia Harbeck

Onco Targets Ther 2014 6;7:1723-31. Epub 2014 Oct 6.

Breast Center, Department of Gynecology and Obstetrics, Ludwig-Maximilian-University Munich, Munich, Germany.

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October 2014

Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth.

Authors:
Emanuele Zanucco Nefertiti El-Nikhely Rudolf Götz Katharina Weidmann Verena Pfeiffer Rajkumar Savai Werner Seeger Axel Ullrich Ulf R Rapp

J Biol Chem 2014 Sep 5;289(39):26804-16. Epub 2014 Aug 5.

From the Department of Molecular Biology, Max Planck Institute of Biochemistry, 85152 Martinsried, Germany,

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September 2014

Discovery and Biological Evaluation of Novel Dual EGFR/c-Met Inhibitors.

Authors:
Bálint Szokol Pál Gyulavári Ibolya Kurkó Ferenc Baska Csaba Szántai-Kis Zoltán Greff Zoltán Orfi István Peták Kinga Pénzes Robert Torka Axel Ullrich László Orfi Tibor Vántus György Kéri

ACS Med Chem Lett 2014 Apr 30;5(4):298-303. Epub 2014 Jan 30.

Vichem Chemie Research Ltd. , 1022 Budapest, Hungary ; MTA-SE Pathobiochemistry Research Group, Department of Medical Chemistry, Semmelweis University , 1085 Budapest, Hungary ; Rational Drug-Design Laboratory Cooperation Research Centre, Semmelweis University , 1085 Budapest, Hungary.

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April 2014

Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy.

Authors:
Robert Torka Kinga Pénzes Simone Gusenbauer Christine Baumann István Szabadkai Lászlȯ Őrfi György Kéri Axel Ullrich

Neoplasia 2014 Apr;16(4):301-18

Department of Molecular Biology, Max Planck Institute of Biochemistry, Martinsried, Germany.

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April 2014

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma.

Authors:
Han Kiat Ho Boon Tin Chua Winnie Wong Kah Suan Lim Vivian Teo Hooi-Tin Ong Xiao Chen Wei Zhang Kam M Hui Mei Lin Go Axel Ullrich

Mol Oncol 2014 Oct 2;8(7):1266-77. Epub 2014 May 2.

Singapore OncoGenome Laboratory, Institute of Molecular and Cell Biology, A*STAR, Singapore; Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany.

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October 2014

[Development and biochemical characterization of EGFR/c-Met dual inhibitors].

Authors:
Bálint Szokol Pál Gyulavári Ferenc Baska Kurkó Ibolya Zoltán Greff Kis-Csaba Szántai Orfi Zoltán István Peták Ullrich Axel Tibor Vantus György Kéri László Orfi

Acta Pharm Hung 2013 ;83(4):121-33

Vichem Chemie Kutató Kft.

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April 2014

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.

Authors:
Magdalena Paolino Axel Choidas Stephanie Wallner Blanka Pranjic Iris Uribesalgo Stefanie Loeser Amanda M Jamieson Wallace Y Langdon Fumiyo Ikeda Juan Pablo Fededa Shane J Cronin Roberto Nitsch Carsten Schultz-Fademrecht Jan Eickhoff Sascha Menninger Anke Unger Robert Torka Thomas Gruber Reinhard Hinterleitner Gottfried Baier Dominik Wolf Axel Ullrich Bert M Klebl Josef M Penninger

Nature 2014 Mar 19;507(7493):508-12. Epub 2014 Feb 19.

IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, 1030 Vienna, Austria.

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March 2014

Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer.

Authors:
Daniel S W Tan Benjamin Haaland Jia Min Gan Su Chin Tham Indrajit Sinha Eng Huat Tan Kiat Hon Lim Angela Takano Sai Sakktee Krisna Minn Minn Myint Thu Hoe Peng Liew Axel Ullrich Wan-Teck Lim Boon Tin Chua

Mol Cancer 2014 Jan 24;13:13. Epub 2014 Jan 24.

Singapore OncoGenome Laboratory, Institute of Medical Biology, Agency of Science Technology and Research, Singapore, Singapore.

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January 2014

PTK 7 is a transforming gene and prognostic marker for breast cancer and nodal metastasis involvement.

Authors:
Silvia Gärtner Angela Gunesch Tatiana Knyazeva Petra Wolf Bernhard Högel Wolfgang Eiermann Axel Ullrich Pjotr Knyazev Beyhan Ataseven

PLoS One 2014 7;9(1):e84472. Epub 2014 Jan 7.

Department of Gynecology and Obstetrics, Red Cross Hospital, Munich, Germany ; Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung, Essen, Germany.

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September 2014

The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.

Authors:
Shereen Ezzat Lei Zheng Jose C Florez Norbert Stefan Thomas Mayr Maw Maw Hliang Kathleen Jablonski Maegan Harden Alena Stančáková Markku Laakso Hans-Ulrich Haring Axel Ullrich Sylvia L Asa

Cell Metab 2013 Jun;17(6):929-940

Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2M9, Canada.

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June 2013

NEK9 depletion induces catastrophic mitosis by impairment of mitotic checkpoint control and spindle dynamics.

Authors:
Yasuyuki Kaneta Axel Ullrich

Biochem Biophys Res Commun 2013 Dec 9;442(3-4):139-46. Epub 2013 May 9.

Max-Planck-Institute of Biochemistry, Department of Molecular Biology, Martinsried, Germany; Shinagawa R&D Center, Daiichi Sankyo Co. Ltd., Tokyo, Japan. Electronic address:

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December 2013

Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator.

Authors:
Philip Vlaicu Philipp Mertins Thomas Mayr Peter Widschwendter Beyhan Ataseven Bernhard Högel Wolfgang Eiermann Pjotr Knyazev Axel Ullrich

BMC Cancer 2013 Apr 18;13:197. Epub 2013 Apr 18.

Department of Molecular Biology, Max Planck Institute of Biochemistry, Martinsried 82152, Germany.

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April 2013

LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis.

Authors:
Enza Piccolo Nicola Tinari Daniela Semeraro Sara Traini Imma Fichera Albana Cumashi Rossana La Sorda Francesca Spinella Anna Bagnato Rossano Lattanzio Maurizia D'Egidio Annalisa Di Risio Pavlos Stampolidis Mauro Piantelli Clara Natoli Axel Ullrich Stefano Iacobelli

J Mol Med (Berl) 2013 Jan 5;91(1):83-94. Epub 2012 Aug 5.

MediaPharma s.r.l., Via Colle dell'Ara, Chieti, Italy.

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January 2013

Inhibition of doxorubicin-induced HER3-PI3K-AKT signalling enhances apoptosis of ovarian cancer cells.

Authors:
Martin Bezler Jan G Hengstler Axel Ullrich

Mol Oncol 2012 Oct 20;6(5):516-29. Epub 2012 Jul 20.

Max-Planck-Institute of Biochemistry, Department of Molecular Biology, Martinsried, Germany.

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October 2012

Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells.

Authors:
Prajakta S Oak Florian Kopp Chitra Thakur Joachim W Ellwart Ulf R Rapp Axel Ullrich Ernst Wagner Pjotr Knyazev Andreas Roidl

Int J Cancer 2012 Dec 21;131(12):2808-19. Epub 2012 May 21.

Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians Universität München, Munich, Germany.

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December 2012

The FGFR4-G388R polymorphism promotes mitochondrial STAT3 serine phosphorylation to facilitate pituitary growth hormone cell tumorigenesis.

Authors:
Toru Tateno Sylvia L Asa Lei Zheng Thomas Mayr Axel Ullrich Shereen Ezzat

PLoS Genet 2011 Dec 8;7(12):e1002400. Epub 2011 Dec 8.

Ontario Cancer Institute, University Health Network, Toronto, Canada.

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December 2011

Toward the prognostic significance and therapeutic potential of HER3 receptor tyrosine kinase in human colon cancer.

Authors:
Abdelhamid Beji David Horst Jutta Engel Thomas Kirchner Axel Ullrich

Clin Cancer Res 2012 Feb 5;18(4):956-68. Epub 2011 Dec 5.

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Munich, Germany.

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February 2012

PRKX, TTBK2 and RSK4 expression causes Sunitinib resistance in kidney carcinoma- and melanoma-cell lines.

Authors:
Claus Bender Axel Ullrich

Int J Cancer 2012 Jul 28;131(2):E45-55. Epub 2012 Feb 28.

Department of Molecular Biology, Max-Planck-Institute, Martinsried, Germany.

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July 2012

Visceral obesity and inflammation markers in relation to serum prostate volume biomarkers among apparently healthy men.

Authors:
Majed S Alokail Nasser M Al-Daghri Omar S Al-Attas Khalid M Alkharfy Shaun B Sabico Axel Ullrich

Eur J Clin Invest 2011 Sep 7;41(9):987-94. Epub 2011 Mar 7.

Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.

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September 2011

Somatic mutation in the ACK1 ubiquitin association domain enhances oncogenic signaling through EGFR regulation in renal cancer derived cells.

Authors:
Boon Tin Chua Shu Jing Lim Su Chin Tham Wei Jie Poh Axel Ullrich

Mol Oncol 2010 Aug 19;4(4):323-34. Epub 2010 Mar 19.

Singapore OncoGenome Project, Institute of Medical Biology, A* STAR, 8A Biomedical Grove, #06-06 Immunos, Singapore 138648, Singapore.

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August 2010

A single nucleotide change in the mouse genome accelerates breast cancer progression.

Authors:
Nina Seitzer Thomas Mayr Sylvia Streit Axel Ullrich

Cancer Res 2010 Jan 12;70(2):802-12. Epub 2010 Jan 12.

Department of Molecular Biology, Max Planck Institute of Biochemistry, 85152 Martinsried, Germany.

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January 2010

Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma.

Authors:
Markus Reschke Ingvar Ferby Ewa Stepniak Nina Seitzer David Horst Erwin F Wagner Axel Ullrich

Hepatology 2010 Apr;51(4):1383-90

Max-Planck Institute of Biochemistry, Department of Molecular Biology, Martinsried, Germany.

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April 2010

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells.

Authors:
Boon Tin Chua David Gallego-Ortega Ana Ramirez de Molina Axel Ullrich Juan Carlos Lacal Julian Downward

Mol Cancer 2009 Dec 31;8:131. Epub 2009 Dec 31.

Singapore OncoGenome Project, Institute of Medical Biology, A*STAR, 8A Biomedical Grove, 06-06 Immunos, Singapore.

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December 2009

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

Authors:
Jacqueline Reinhard Andrea Horvat-Bröcker Sebastian Illes Angelika Zaremba Piotr Knyazev Axel Ullrich Andreas Faissner

Exp Brain Res 2009 Dec 1;199(3-4):279-97. Epub 2009 Sep 1.

Department of Cell Morphology and Molecular Neurobiology, Faculty of Biology, Ruhr-University Bochum, Universitaetsstr 150, 44780, Bochum, Germany.

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December 2009

Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction.

Authors:
Arnaud Descot Reinhard Hoffmann Dmitry Shaposhnikov Markus Reschke Axel Ullrich Guido Posern

Mol Cell 2009 Aug;35(3):291-304

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany.

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August 2009

Resistance to chemotherapy is associated with fibroblast growth factor receptor 4 up-regulation.

Authors:
Andreas Roidl Hans-Jürgen Berger Sushil Kumar Johannes Bange Pjotr Knyazev Axel Ullrich

Clin Cancer Res 2009 Mar 24;15(6):2058-66. Epub 2009 Feb 24.

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany.

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March 2009

Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy.

Authors:
Marcus Czabanka Mara Vinci Frank Heppner Axel Ullrich Peter Vajkoczy

Int J Cancer 2009 Mar;124(6):1293-300

Department of Neurosurgery, Universitätsmedizin Charitè, Berlin, Germany.

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March 2009

Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention.

Authors:
Han Kiat Ho Sharon Pok Sylvia Streit Jens E Ruhe Stefan Hart Kah Suan Lim Hooi Linn Loo Myat Oo Aung Seng Gee Lim Axel Ullrich

J Hepatol 2009 Jan 12;50(1):118-27. Epub 2008 Oct 12.

Singapore OncoGenome Laboratory, Institute of Medical Biology, A *STAR, 8A Biomedical Grove, #06-06 Immunos, Singapore 138648, Singapore.

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January 2009

UV-induced EGFR signal transactivation is dependent on proligand shedding by activated metalloproteases in skin cancer cell lines.

Authors:
Bhuminder Singh Matthias Schneider Pjotr Knyazev Axel Ullrich

Int J Cancer 2009 Feb;124(3):531-9

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany.

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February 2009

HER3 is a determinant for poor prognosis in melanoma.

Authors:
Markus Reschke Daniela Mihic-Probst Edward Htun van der Horst Pjotr Knyazev Peter J Wild Markus Hutterer Stefanie Meyer Reinhard Dummer Holger Moch Axel Ullrich

Clin Cancer Res 2008 Aug;14(16):5188-97

Department of Molecular Biology, Max-Planck Institute of Biochemistry, Munich, Germany.

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August 2008

Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.

Authors:
Philipp Mertins H Christian Eberl Jörg Renkawitz Jesper V Olsen Michel L Tremblay Matthias Mann Axel Ullrich Henrik Daub

Mol Cell Proteomics 2008 Sep 31;7(9):1763-77. Epub 2008 May 31.

Department of Molecular Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.

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September 2008

Paul Ehrlich's magic bullet concept: 100 years of progress.

Authors:
Klaus Strebhardt Axel Ullrich

Nat Rev Cancer 2008 06 12;8(6):473-80. Epub 2008 May 12.

Klaus Strebhardt is at the Department of Obstetrics and Gynaecology, School of Medicine, J.W. Goethe-University, Theodour-Stern-Kai 7, 60590 Frankfurt, Germany.

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June 2008

Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer.

Authors:
Nikolas H Stoecklein Stefan B Hosch Martin Bezler Franziska Stern Claudia H Hartmann Christian Vay Annika Siegmund Peter Scheunemann Paulus Schurr Wolfram T Knoefel Pablo E Verde Uta Reichelt Andreas Erbersdobler Roger Grau Axel Ullrich Jakob R Izbicki Christoph A Klein

Cancer Cell 2008 May;13(5):441-53

Department of Pathology, Division of Oncogenomics, University of Regensburg, D-93053 Regensburg, Germany.

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May 2008

SHPS-1/SIRP1alpha contributes to interleukin-6 signalling.

Authors:
Radoslaw M Sobota Pia J Müller Christina Khouri Axel Ullrich Valeria Poli Tetsuya Noguchi Peter C Heinrich Fred Schaper

Cell Signal 2008 Jul 21;20(7):1385-91. Epub 2008 Mar 21.

Department of Biochemistry, RWTH Aachen University, Pauwelsstrasse 30, D-52074 Aachen, Germany.

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July 2008

AXL is a potential target for therapeutic intervention in breast cancer progression.

Authors:
Yi-Xiang Zhang Peter G Knyazev Yuri V Cheburkin Kirti Sharma Yuri P Knyazev László Orfi István Szabadkai Henrik Daub György Kéri Axel Ullrich

Cancer Res 2008 Mar;68(6):1905-15

Max Planck Institute of Biochemistry, Martinsried, Germany.

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March 2008

Axl and growth arrest-specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme.

Authors:
Markus Hutterer Pjotr Knyazev Ariane Abate Markus Reschke Hans Maier Nadia Stefanova Tatjana Knyazeva Verena Barbieri Markus Reindl Armin Muigg Herwig Kostron Guenther Stockhammer Axel Ullrich

Clin Cancer Res 2008 Jan;14(1):130-8

Clinical Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.

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January 2008

Development of Targeted Therapies in ErbB2-Positive Breast Cancer.

Authors:
Christian Jackisch Josef Rüschoff Axel Ullrich

Breast Care (Basel) 2008;3(s1):3-6. Epub 2008 Apr 24.

Department of Obstetrics and Gynecology and Breast Cancer Center, Klinikum Offenbach GmbH, Kassel, Germany.

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April 2008

Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines.

Authors:
Jens E Ruhe Sylvia Streit Stefan Hart Chee-Hong Wong Katja Specht Pjotr Knyazev Tatjana Knyazeva Liang Seah Tay Hooi Linn Loo Priscilla Foo Winnie Wong Sharon Pok Shu Jing Lim Huimin Ong Ming Luo Han Kiat Ho Kaitian Peng Tze Chuen Lee Martin Bezler Christian Mann Silvia Gaertner Heinz Hoefler Stefano Iacobelli Stephan Peter Alice Tay Sydney Brenner Byrappa Venkatesh Axel Ullrich

Cancer Res 2007 Dec;67(23):11368-76

Institute of Medical Biology, Singapore, Singapore.

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December 2007

Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death.

Authors:
Attila Steták Réka Veress Judit Ovádi Péter Csermely György Kéri Axel Ullrich

Cancer Res 2007 Feb;67(4):1602-8

Department of Molecular Biology, Max-Planck-Institute for Biochemistry, Martinsried, Germany.

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February 2007

Another look at imatinib mesylate.

Authors:
Klaus Strebhardt Axel Ullrich

N Engl J Med 2006 Dec;355(23):2481-2

Department of Obstetrics and Gynecology, School of Medicine, J.W. Goethe University, Frankfurt, Germany.

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December 2006

Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling.

Authors:
Yiguo Wang Dan Du Longhou Fang Guang Yang Chenyi Zhang Rong Zeng Axel Ullrich Friedrich Lottspeich Zhengjun Chen

EMBO J 2006 Nov 19;25(21):5058-70. Epub 2006 Oct 19.

Key Laboratory of Proteomics and Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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November 2006

Endothelin-1 inhibits adipogenesis: role of phosphorylation of Akt and ERK1/2.

Authors:
Indranil Bhattacharya Axel Ullrich

FEBS Lett 2006 Oct 27;580(24):5765-71. Epub 2006 Sep 27.

Department of Molecular Biology, Max Planck Institute for Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.

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October 2006

PTP-PEST phosphatase variations in human cancer.

Authors:
Sylvia Streit Jens Ernst Ruhe Pjotr Knyazev Tatjana Knyazeva Stefano Iacobelli Stephan Peter Heinz Hoefler Axel Ullrich

Cancer Genet Cytogenet 2006 Oct;170(1):48-53

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18a, D-82152 Martinsried, Germany.

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October 2006

ErbB-3 predicts survival in ovarian cancer.

Authors:
Berno Tanner Dirk Hasenclever Katja Stern Wiebke Schormann Martin Bezler Matthias Hermes Marc Brulport Alexander Bauer Ilka B Schiffer Susanne Gebhard Markus Schmidt Eric Steiner Jalid Sehouli Jeanett Edelmann Jürgen Läuter Rüdiger Lessig K Krishnamurthi Axel Ullrich Jan Georg Hengstler

J Clin Oncol 2006 Sep 8;24(26):4317-23. Epub 2006 Aug 8.

Department of Gynecology and Obstetrics, University of Mainz, Mainz, Germany.

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September 2006

Active antimetastatic immunotherapy in Lewis lung carcinoma with self EGFR extracellular domain protein in VSSP adjuvant.

Authors:
Belinda Sánchez Ramírez Eduardo Suárez Pestana Greta Garrido Hidalgo Tays Hernández García Rolando Pérez Rodríguez Axel Ullrich Luis Enrique Férnandez

Int J Cancer 2006 Nov;119(9):2190-9

Vaccine Department, Center of Molecular Immunology, Havana, Cuba.

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November 2006

FGFR4 Arg388 allele is associated with resistance to adjuvant therapy in primary breast cancer.

Authors:
Christoph Thussbas Jorg Nahrig Sylvia Streit Johannes Bange Monika Kriner Ronald Kates Kurt Ulm Marion Kiechle Heinz Hoefler Axel Ullrich Nadia Harbeck

J Clin Oncol 2006 Aug 5;24(23):3747-55. Epub 2006 Jul 5.

Department of Obstetrics and Gynecology, Institute of Pathology, and Institute for Medical Statistics and Epidemiology, Technical University of Munich, Munich, Germany.

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August 2006

Dissecting the epidermal growth factor receptor signal transactivation pathway.

Authors:
Oliver M Fischer Stefan Hart Axel Ullrich

Methods Mol Biol 2006 ;327:85-97

Pfizer Global Research and Development, Sandwich Laboratories, Kent, UK.

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July 2006

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation.

Authors:
Ingvar Ferby Markus Reschke Oliver Kudlacek Pjotr Knyazev Guido Pantè Kerstin Amann Wolfgang Sommergruber Norbert Kraut Axel Ullrich Reinhard Fässler Rüdiger Klein

Nat Med 2006 May 30;12(5):568-73. Epub 2006 Apr 30.

Department of Molecular Neurobiology, Max-Planck Institute of Neurobiology, Klopferspitz 18, 82152 Martinsried, Germany.

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May 2006

Furin-, ADAM 10-, and gamma-secretase-mediated cleavage of a receptor tyrosine phosphatase and regulation of beta-catenin's transcriptional activity.

Authors:
Lars Anders Philipp Mertins Sven Lammich Marta Murgia Dieter Hartmann Paul Saftig Christian Haass Axel Ullrich

Mol Cell Biol 2006 May;26(10):3917-34

Department of Molecular Biology, Max Planck Institute of Biochemistry, Martinsried, Germany.

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May 2006

Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1.

Authors:
Olga Sukocheva Carol Wadham Andrew Holmes Nathaniel Albanese Emily Verrier Feng Feng Alex Bernal Claudia K Derian Axel Ullrich Mathew A Vadas Pu Xia

J Cell Biol 2006 Apr;173(2):301-10

Signal Transduction Laboratory, Division of Human Immunology, Hanson Institute, Institute of Medical and Veterinary Science, Adelaide SA 5000, Australia.

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April 2006

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival.

Authors:
Peter Vajkoczy Pjotr Knyazev Andrea Kunkel Hans-Holger Capelle Sandra Behrndt Hendrik von Tengg-Kobligk Fabian Kiessling Uta Eichelsbacher Marco Essig Tracy-Ann Read Ralf Erber Axel Ullrich

Proc Natl Acad Sci U S A 2006 Apr 3;103(15):5799-804. Epub 2006 Apr 3.

Department of Neurosurgery, Medical Faculty of the University of Heidelberg, D-68167 Mannheim, Germany.

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April 2006

Targeting polo-like kinase 1 for cancer therapy.

Authors:
Klaus Strebhardt Axel Ullrich

Nat Rev Cancer 2006 04;6(4):321-30

Department of Obstetrics and Gynecology, School of Medicine, J.W. Goethe-University, Theodore-Stern-Kai 7, 60590 Frankfurt, Germany.

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April 2006

EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing.

Authors:
Jens E Ruhe Sylvia Streit Stefan Hart Axel Ullrich

Cell Signal 2006 Sep 14;18(9):1515-27. Epub 2006 Feb 14.

Department of Molecular Biology, Max-Planck-Institute for Biochemistry, Am Klopferspitz 18A, D-82152 Martinsried, Germany.

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September 2006

EphB4 controls blood vascular morphogenesis during postnatal angiogenesis.

Authors:
Ralf Erber Uta Eichelsbacher Violetta Powajbo Tobias Korn Valentin Djonov Jihong Lin Hans-Peter Hammes Rainer Grobholz Axel Ullrich Peter Vajkoczy

EMBO J 2006 Feb 19;25(3):628-41. Epub 2006 Jan 19.

Department of Neurosurgery, Faculty for Clinical Medicine of the University of Heidelberg, University Hospital Mannheim, Mannheim, Germany.

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February 2006

Structural basis for Gas6-Axl signalling.

Authors:
Takako Sasaki Pjotr G Knyazev Naomi J Clout Yuri Cheburkin Walter Göhring Axel Ullrich Rupert Timpl Erhard Hohenester

EMBO J 2006 Jan 15;25(1):80-7. Epub 2005 Dec 15.

Max-Planck-Institut für Biochemie, Martinsried, Germany.

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January 2006

Drug discovery in the kinase inhibitory field using the Nested Chemical Library technology.

Authors:
György Kéri Zsolt Székelyhidi Péter Bánhegyi Zoltán Varga Bálint Hegymegi-Barakonyi Csaba Szántai-Kis Doris Hafenbradl Bert Klebl Gerhard Muller Axel Ullrich Dániel Erös Zoltán Horváth Zoltán Greff Jenö Marosfalvi János Pató István Szabadkai Ildikó Szilágyi Zsolt Szegedi István Varga Frigyes Wáczek László Orfi

Assay Drug Dev Technol 2005 Oct;3(5):543-51

Peptide Biochemistry Research Group of Hungarian Academy of Sciences in Department of Medicinal Chemistry and Pathobiochemistry and Rational Drug Design Laboratory Cooperative Research Center, Semmelweis University, Budapest, Hungary.

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October 2005

GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways.

Authors:
Stefan Hart Oliver M Fischer Norbert Prenzel Esther Zwick-Wallasch Matthias Schneider Lothar Hennighausen Axel Ullrich

Biol Chem 2005 Sep;386(9):845-55

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18A, D-82152 Martinsried, Germany.

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September 2005

FGFR4 GLY388 isotype suppresses motility of MDA-MB-231 breast cancer cells by EDG-2 gene repression.

Authors:
Christiane Regina Stadler Pjotr Knyazev Johannes Bange Axel Ullrich

Cell Signal 2006 Jun 18;18(6):783-94. Epub 2005 Aug 18.

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18a, D-82152 Martinsried, Germany.

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June 2006

Identification of MMP-15 as an anti-apoptotic factor in cancer cells.

Authors:
Reimar Abraham Juliane Schäfer Mike Rothe Johannes Bange Pjotr Knyazev Axel Ullrich

J Biol Chem 2005 Oct 9;280(40):34123-32. Epub 2005 Aug 9.

Department of Molecular Biology, Max-Planck-Institute for Biochemistry, 82152 Martinsried, Germany.

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October 2005

Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling.

Authors:
Klaus Godl Oliver J Gruss Jan Eickhoff Josef Wissing Stephanie Blencke Martina Weber Heidrun Degen Dirk Brehmer László Orfi Zoltán Horváth György Kéri Stefan Müller Matt Cotten Axel Ullrich Henrik Daub

Cancer Res 2005 Aug;65(15):6919-26

Axxima Pharmaceuticals AG, Munich, Germany.

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August 2005

Identification of a transcriptionally active hVH-5 pseudogene on 10q22.2.

Authors:
Ingemarie R Berger Marcus Buschbeck Johannes Bange Axel Ullrich

Cancer Genet Cytogenet 2005 Jun;159(2):155-9

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18a, D-82152 Martinsried, Germany.

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June 2005

Combined inhibition of vascular endothelial growth factor and platelet-derived growth factor signaling: effects on the angiogenesis, microcirculation, and growth of orthotopic malignant gliomas.

Authors:
Mohammad Reza Farhadi Hans Holger Capelle Ralf Erber Axel Ullrich Peter Vajkoczy

J Neurosurg 2005 Feb;102(2):363-70

Department of Neurosurgery, University Hospital, Faculty of Clinical Medicine, University of Heidelberg, Mannheim, Germany.

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February 2005

Anti-HER-3 MAbs inhibit HER-3-mediated signaling in breast cancer cell lines resistant to anti-HER-2 antibodies.

Authors:
Edward Htun van der Horst Marta Murgia Martin Treder Axel Ullrich

Int J Cancer 2005 Jul;115(4):519-27

Department of Molecular Biology, Max Planck Institute for Biochemistry, Martinsried, Munich, Germany.

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July 2005

Abl-kinase-sensitive levels of ERK5 and its intrinsic basal activity contribute to leukaemia cell survival.

Authors:
Marcus Buschbeck Sebastian Hofbauer Luciano Di Croce Gyorgy Keri Axel Ullrich

EMBO Rep 2005 Jan;6(1):63-9

Department of Molecular Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18a, 82152 Martinsried, Germany.

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January 2005

TaqMan-based quantification of invasive cells in the chick embryo metastasis assay.

Authors:
Edward Htun van der Horst Jörg H Leupold Rainer Schubbert Axel Ullrich Heike Allgayer

Biotechniques 2004 Dec;37(6):940-2, 944, 946

U3Pharma, Martinsried, Germany.

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December 2004

Strategies to overcome resistance to targeted protein kinase inhibitors.

Authors:
Henrik Daub Katja Specht Axel Ullrich

Nat Rev Drug Discov 2004 Dec;3(12):1001-10

Axxima Pharmaceuticals AG, Max-Lebsche-Platz 32, 81377 München, Germany.

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December 2004

The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling.

Authors:
Marcus Buschbeck Axel Ullrich

J Biol Chem 2005 Jan 17;280(4):2659-67. Epub 2004 Nov 17.

Max-Planck-Institute of Biochemistry, Department of Molecular Biology, D-82152 Martinsried, Germany.

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January 2005

Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma.

Authors:
Edward Htun van der Horst Igor Weber Axel Ullrich

Int J Cancer 2005 Feb;113(5):689-98

Department of Molecular Biology, Max Planck Institute for Biochemistry, Munich, Germany.

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February 2005

Effect of tumor-associated mutant E-cadherin variants with defects in exons 8 or 9 on matrix metalloproteinase 3.

Authors:
Margit Fuchs Christine Hermannstädter Katja Specht Pjotr Knyazev Axel Ullrich Erika Rosivatz Raymonde Busch Peter Hutzler Heinz Höfler Birgit Luber

J Cell Physiol 2005 Mar;202(3):805-13

Technische Universität München, Klinikum rechts der Isar, Institut für Allgemeine Pathologie und Pathologische Anatomie, München, Germany.

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March 2005

Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.

Authors:
Beatrix Schäfer Beatrice Marg Andreas Gschwind Axel Ullrich

J Biol Chem 2004 Nov 26;279(46):47929-38. Epub 2004 Aug 26.

Department of Molecular Biology, Max-Planck Institute of Biochemistry, Martinsried D-82152, Germany.

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November 2004

Protein tyrosine kinase Syk modulates EGFR signalling in human mammary epithelial cells.

Authors:
Anja Ruschel Axel Ullrich

Cell Signal 2004 Nov;16(11):1249-61

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.

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November 2004

Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.

Authors:
Ling Zhao Stefan Hart JrGang Cheng J Joseph Melenhorst Brian Bierie Matthias Ernst Colin Stewart Fred Schaper Peter C Heinrich Axel Ullrich Gertraud W Robinson Lothar Hennighausen

J Biol Chem 2004 Oct 30;279(42):44093-100. Epub 2004 Jul 30.

Laboratory of Genetics and Physiology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA.

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October 2004

Involvement of the FGFR4 Arg388 allele in head and neck squamous cell carcinoma.

Authors:
Sylvia Streit Johannes Bange Alexander Fichtner Stephan Ihrler Wolfgang Issing Axel Ullrich

Int J Cancer 2004 Aug;111(2):213-7

Department of Molecular Biology, Max Planck Institute for Biochemistry, Martinsried, Germany.

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August 2004

Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor.

Authors:
Oliver M Fischer Stefan Hart Andreas Gschwind Norbert Prenzel Axel Ullrich

Mol Cell Biol 2004 Jun;24(12):5172-83

Department of Molecular Biology, Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany.

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June 2004

Cell surface growth factor receptor molecules as targets for cancer therapy.

Authors:
Oliver M Fischer Andreas Gschwind Axel A Ullrich

Discov Med 2004 Jun;4(22):166-71

Pfizer, Ltd., Sandwich, UK.

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June 2004

Characterization of a conserved structural determinant controlling protein kinase sensitivity to selective inhibitors.

Authors:
Stephanie Blencke Birgit Zech Ola Engkvist Zoltán Greff László Orfi Zoltán Horváth György Kéri Axel Ullrich Henrik Daub

Chem Biol 2004 May;11(5):691-701

Axxima Pharmaceuticals AG, Max-Lebsche-Platz 32, 81377 Munich, Germany.

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May 2004

Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling.

Authors:
Luca Cardone Annalisa Carlucci Adele Affaitati Alessandra Livigni Tiziana DeCristofaro Corrado Garbi Stelio Varrone Axel Ullrich Max E Gottesman Enrico V Avvedimento Antonio Feliciello

Mol Cell Biol 2004 Jun;24(11):4613-26

Dipartimento di Biologia e Patologia Molecolare e Cellulare, via S. Pansini, 5, 80131 Naples, Italy.

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June 2004

Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells.

Authors:
Oliver M Fischer Silvia Giordano Paolo M Comoglio Axel Ullrich

J Biol Chem 2004 Jul 29;279(28):28970-8. Epub 2004 Apr 29.

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18A, D-82152 Martinsried, Germany.

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July 2004

The discovery of receptor tyrosine kinases: targets for cancer therapy.

Authors:
Andreas Gschwind Oliver M Fischer Axel Ullrich

Nat Rev Cancer 2004 05;4(5):361-70

Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

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May 2004

Interplay between mycobacteria and host signalling pathways.

Authors:
Anil Koul Thomas Herget Bert Klebl Axel Ullrich

Nat Rev Microbiol 2004 Mar;2(3):189-202

Axxima Pharmaceuticals AG, Max-Lebsche-Platz 32, 81377 Munich, Germany.

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March 2004

The ability of protein tyrosine phosphatase SHP-1 to suppress NFkappaB can be inhibited by dominant negative mutant of SIRPalpha.

Authors:
Nickolay Neznanov Lubov Neznanova Roman V Kondratov Donald M O'Rourke Axel Ullrich Andrei V Gudkov

DNA Cell Biol 2004 Mar;23(3):175-82

Department of Virology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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March 2004

Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor.

Authors:
Stefan Hart Oliver M Fischer Axel Ullrich

Cancer Res 2004 Mar;64(6):1943-50

Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18A, D-82152 Martinsried, Germany.

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March 2004

Peptide-mediated inhibition of neutrophil transmigration by blocking CD47 interactions with signal regulatory protein alpha.

Authors:
Yuan Liu Miriam B O'Connor Kenneth J Mandell Ke Zen Axel Ullrich Hans-Jörg Bühring Charles A Parkos

J Immunol 2004 Feb;172(4):2578-85

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.

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February 2004