Axel Meissner

Axel Meissner

UNVERIFIED PROFILE

Are you Axel Meissner?   Register this Author

Register author
Axel Meissner

Axel Meissner

Publications by authors named "Axel Meissner"

Are you Axel Meissner?   Register this Author

58Publications

635Reads

10Profile Views

Metabolism and Disposition of Siponimod, a Novel Selective S1P/S1P Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism.

Drug Metab Dispos 2018 07 7;46(7):1001-1013. Epub 2018 May 7.

PK-Sciences, Novartis Pharma AG, Basel, Switzerland (U.G., Y.J., R.N., W.L., K.S., S.A.-S., E.L., H.B., A.D.J., A.M., G.C., A.G.), and PRA Health Sciences, Raleigh, North Carolina (S.P.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.117.079574DOI Listing
July 2018

[Heart Failure Despite Low BNP-Level: Paradoxon or Pathfinder? - - A Case of Pericarditis constrictiva].

Dtsch Med Wochenschr 2018 May 4;143(10):731-734. Epub 2018 May 4.

Medizinische Klinik II, Klinik für Kardiologie, Rhythmologie und internistische Intensivmedizin, Klinikum Köln-Merheim, Universität Witten-Herdecke, Köln.

View Article

Download full-text PDF

Source
http://www.thieme-connect.de/DOI/DOI?10.1055/a-0600-1645
Publisher Site
http://dx.doi.org/10.1055/a-0600-1645DOI Listing
May 2018

Point-by-point versus multisite electrode mapping in VT ablation: does freedom from VT recurrences depend on mapping catheter? An observational study.

J Interv Card Electrophysiol 2018 Mar 22;51(2):169-181. Epub 2018 Jan 22.

Department of Cardiology, Electrophysiology and Intensive Care, Klinikum Merheim, University Witten/Herdecke/Germany, Ostmerheimer Str. 200, 51109, Cologne, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10840-018-0311-9
Publisher Site
http://dx.doi.org/10.1007/s10840-018-0311-9DOI Listing
March 2018

Interconversion Rates between Conformational States as Rationale for the Membrane Permeability of Cyclosporines.

Chemphyschem 2017 Dec 2;18(23):3309-3314. Epub 2017 Nov 2.

Laboratory of Physical Chemistry, ETH Zürich, Vladimir-Prelog-Weg 2, 8093, Zürich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cphc.201700995DOI Listing
December 2017

High-Density Mapping in Ventricular Tachycardia Ablation: A PentaRay Study.

Cardiol Res 2017 Dec 22;8(6):293-303. Epub 2017 Dec 22.

Department of Cardiology, Electrophysiology and Intensive Care, Klinikum Merheim, University Witten/Herdecke/Germany, Ostmerheimer Str. 200, 51109 Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14740/cr636wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755661PMC
December 2017

Correction to Kinetic Models of Cyclosporin A in Polar and Apolar Environments Reveal Multiple Congruent Conformational States.

J Chem Inf Model 2017 09 12;57(9):2393. Epub 2017 Sep 12.

Laboratory of Physical Chemistry, ETH Zürich , Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jcim.7b00502DOI Listing
September 2017

Comparison of F NMR and C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans.

Drug Metab Dispos 2017 08 31;45(8):900-907. Epub 2017 May 31.

PK Sciences (ADME), Novartis Institutes for Biomedical Research, Basel, Switzerland (A.D.J., C.M., G.C.); and AX, Global Discovery Chemistry, Novartis Institutes for Biomedical Research Basel, Switzerland (A.L., A.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.117.075424DOI Listing
August 2017

Pulmonary vein potential mapping in atrial fibrillation with high density and standard spiral (lasso) catheters: A comparative study.

J Arrhythm 2017 Jun 25;33(3):192-200. Epub 2016 Nov 25.

Department of Cardiology and Angiology, Johanniter-Krankenhaus Rheinhausen GmbH, Kreuzacker 1-7, 47228 Duisburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.joa.2016.10.562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459413PMC
June 2017

Impact of High-Intensity-NIV on the heart in stable COPD: a randomised cross-over pilot study.

Respir Res 2017 05 2;18(1):76. Epub 2017 May 2.

Cologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH Witten/Herdecke University, Faculty of Health/School of Medicine, Köln, Germany.

View Article

Download full-text PDF

Source
http://respiratory-research.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s12931-017-0542-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414301PMC
May 2017

ECG-Guided Surveillance Technique in Cryoballoon Ablation for Paroxysmal and Persistent Atrial Fibrillation: A Strategy to Prevent From Phrenic Nerve Palsy.

Int J Med Sci 2016 10;13(6):403-11. Epub 2016 May 10.

3. Department of Cardiology and Angiology, Johanniter-Krankenhaus Rheinhausen GmbH, Kreuzacker 1-7, 47228 Duisburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/ijms.14383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893553PMC
April 2017

Impact of Cryoballoon Ablation in Hypertrophic Cardiomyopathy-related Heart Failure due to Paroxysmal Atrial Fibrillation. A Comparative Case Series.

Int J Med Sci 2016 1;13(9):664-72. Epub 2016 Aug 1.

Department of Cardiology, Rhythmology and Internal Intensive Care, Klinikum Köln-Merheim, University Witten-Herdecke, Ostmerheimer Str. 200, 51109 Cologne, Germany; Ruhr-University Bochum, Faculty of Medicine, Universitätsstraße 150, 448801 Bochum, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/ijms.16181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027184PMC
March 2017

Pneumocystis jirovecii-induced chronic interstitial lung disease in Waldenström's macroglobulinemia.

Future Microbiol 2017 03 24;12:307-313. Epub 2017 Feb 24.

Kliniken der Stadt Köln gGmbH, Klinikum der Privaten Universität Witten/Herdecke, Institut für Pathologie, Ostmerheimer Str. 200, D-51109 Köln, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fmb-2016-0188DOI Listing
March 2017

Clinical and Subclinical Femoral Vascular Complications after Deployment of two Different Vascular Closure Devices or Manual Compression in the Setting of Coronary Intervention.

Int J Med Sci 2016 20;13(4):255-9. Epub 2016 Feb 20.

1. Department of Cardiology, Johanniter-Hospital Duisburg Rheinhausen, Germany, Kreuzacker 1-7, 47228 Duisburg / Ruhr-University of Bochum, Universitätsstrasse 150, 44801 Bochum.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/ijms.14476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829537PMC
December 2016

Metabolomic changes in CSF of migraine patients measured with H-NMR spectroscopy.

Mol Biosyst 2016 11;12(12):3674-3682

Department of Neurology, Leiden University Medical Center, P.O. 9600, 2300 WB, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c6mb00424eDOI Listing
November 2016

Is it time to rebalance the case mix? A portfolio analysis of direct catheterization laboratory costs over a 5-year period.

Eur J Med Res 2016 Nov 3;21(1):44. Epub 2016 Nov 3.

Schumpeter School of Business and Economics, University of Wuppertal, Gaussstrasse 20, 42119, Wuppertal, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40001-016-0238-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094137PMC
November 2016

Kinetic Models of Cyclosporin A in Polar and Apolar Environments Reveal Multiple Congruent Conformational States.

J Chem Inf Model 2016 08 19;56(8):1547-62. Epub 2016 Jul 19.

Laboratory of Physical Chemistry, ETH Zürich , Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jcim.6b00251DOI Listing
August 2016

Transradial versus transfemoral approach in coronary angiography: a matched pair analysis of cath lab equipment costs.

J Vasc Access 2015 Sep-Oct;16(5):413-7. Epub 2015 May 30.

1 Department of Cardiology, Johanniter-Hospital Duisburg Rheinhausen, Duisburg - Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5301/jva.5000398DOI Listing
July 2016

Update on the cardiovascular profile of fingolimod in the therapy of relapsing-remitting multiple sclerosis (MS).

Mult Scler Relat Disord 2016 Jul 21;8:19-26. Epub 2016 Apr 21.

Department of Neurology und Palliative Medicine, Cologne-Merheim Hospital Cologne-Merheim Hospital, Academic Hospital of the University of Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.msard.2016.04.002DOI Listing
July 2016

Ethanol contamination of cerebrospinal fluid during standardized sampling and its effect on (1)H-NMR metabolomics.

Anal Bioanal Chem 2015 Jun 3;407(16):4835-9. Epub 2015 May 3.

Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00216-015-8663-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446525PMC
June 2015

Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses.

PLoS Genet 2015 Jan 8;11(1):e1004835. Epub 2015 Jan 8.

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands; Department of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287344PMC
January 2015

1H-NMR metabolic profiling of cerebrospinal fluid in patients with complex regional pain syndrome-related dystonia.

Pain 2014 Jan 11;155(1):190-6. Epub 2013 Oct 11.

Center for Proteomics and Metabolomics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pain.2013.10.005DOI Listing
January 2014

Current treatment and outcome of coronary in-stent restenosis in Sweden: a report from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR).

EuroIntervention 2013 Sep;9(5):564-72

Medizinische Klinik II, Krankenhaus Köln - Merheim, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4244/EIJV9I5A92DOI Listing
September 2013

(1)H NMR-based metabolic profiling of urinary tract infection: combining multiple statistical models and clinical data.

Metabolomics 2012 Dec 29;8(6):1227-1235. Epub 2012 Feb 29.

Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11306-012-0411-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483096PMC
December 2012

Human in vivo longevity is reflected in vitro by differential metabolism as measured by (1)H-NMR profiling of cell culture supernatants.

Mol Biosyst 2012 Mar 4;8(3):783-9. Epub 2012 Jan 4.

Department of Gerontology and Geriatrics, Leiden University Medical Center, RC Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c2mb05237gDOI Listing
March 2012

Metabonomic investigation of human Schistosoma mansoni infection.

Mol Biosyst 2011 May 19;7(5):1473-80. Epub 2011 Feb 19.

Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c0mb00262cDOI Listing
May 2011

New-onset versus chronic atrial fibrillation in acute myocardial infarction: differences in short- and long-term follow-up.

Clin Res Cardiol 2011 Feb 23;100(2):167-75. Epub 2010 Sep 23.

Department of Cardiology and Pneumology, Medizinische Klinik II (Cardiology and Pneumology), St. Marien Hospital Lünen, Academic Teaching Hospital of the University of Münster, Altstadtstr. 23, 44534, Lünen, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00392-010-0227-6
Publisher Site
http://dx.doi.org/10.1007/s00392-010-0227-6DOI Listing
February 2011

The first three-dimensional visualization of a thrombus in transit trapped between the leads of a permanent dual-chamber pacemaker: a case report.

J Med Case Rep 2010 Nov 11;4:359. Epub 2010 Nov 11.

Department of Cardiology and Angiology, Ruhr-University Bochum/Germany, Hölkeskampring 40, 45625 Herne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1752-1947-4-359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994880PMC
November 2010

Eighteen months follow-up of the clinical efficacy of the high density mesh ablator (HDMA) in patients with atrial fibrillation after pulmonary vein isolation.

J Interv Card Electrophysiol 2010 Oct 16;29(1):43-52. Epub 2010 Jul 16.

Department of Cardiology and Angiology, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10840-010-9498-0DOI Listing
October 2010

Metabolic profiling of accelerated aging ERCC1 d/- mice.

J Proteome Res 2010 Jul;9(7):3680-7

Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr100210kDOI Listing
July 2010

Metabolic classification of South American Ilex species by NMR-based metabolomics.

Phytochemistry 2010 May 2;71(7):773-84. Epub 2010 Mar 2.

Division of Pharmacognosy, Institute of Biology, Leiden University, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phytochem.2010.02.001DOI Listing
May 2010

Comparison of right ventricular functional response to exercise in hypertrophic versus idiopathic dilated cardiomyopathy.

Am J Cardiol 2010 Jan 18;105(1):116-21. Epub 2009 Nov 18.

Department of Cardiology and Angiology, Marienhospital Herne, University of Bochum, Bochum, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjcard.2009.08.662DOI Listing
January 2010

Contrast medium induced nephropathy in patients undergoing percutaneous coronary intervention for acute coronary syndrome: differences in STEMI and NSTEMI.

Clin Res Cardiol 2009 Dec 23;98(12):765-72. Epub 2009 Oct 23.

Department of Cardiology and Pneumology, St. Marien Hospital Lünen, Academic Teaching Hospital of the University of Münster, Lünen, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00392-009-0058-5
Publisher Site
http://dx.doi.org/10.1007/s00392-009-0058-5DOI Listing
December 2009

[Paroxysmal and persistent atrial fibrillation: New therapy concepts for pulmonary vein isolation - First clinical experiences with the High Density Mesh Ablator (HDMA)].

Dtsch Med Wochenschr 2009 Sep 10;134(38):1861-7. Epub 2009 Sep 10.

Medizinische Klinik II, Abteilung für Kardiologie und Angiologie, Ruhr-Universität Bochum, Herne.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0029-1237524DOI Listing
September 2009

Multiple cardiac metastases from a malignant melanoma causing consecutive pulmonary embolism.

Herz 2009 Aug;34(5):410-1

Department of Cardiology and Angiology, Marienhospital Herne, Ruhr University Bochum, Herne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00059-009-3253-2DOI Listing
August 2009

Effects of exercise on the duration of diastole and on interventricular phase differences in patients with hypertrophic cardiomyopathy: relationship to cardiac output reserve.

J Nucl Cardiol 2009 Mar-Apr;16(2):233-43. Epub 2009 Jan 22.

Department of Cardiology and Angiology, Marienhospital Herne, University of Bochum, Hölkeskampring 40, 44625, Herne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12350-008-9031-3DOI Listing
July 2009

Prevalence of ventricular discordance and its relation to functional capacity in idiopathic dilated cardiomyopathy.

Clin Res Cardiol 2009 Jun 13;98(6):371-8. Epub 2009 Mar 13.

Department of Cardiology and Angiology, Marienhospital Herne, University of Bochum, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00392-009-0009-1DOI Listing
June 2009

Massive pericarditis constrictiva calcarea with compression of the right ventricle and consecutive pulmonary embolism.

Eur J Echocardiogr 2009 Mar 23;10(2):344-6. Epub 2009 Jan 23.

Department of Cardiology and Angiology, Marienhospital Herne, Ruhr-University Bochum, Hölkeskampring 40, D-44625 Herne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ejechocard/jen331DOI Listing
March 2009

Disproportionate shortening of diastolic time and cardiac performance in asymptomatic patients with aortic regurgitation.

J Heart Valve Dis 2009 Jan;18(1):9-17

Department of Cardiology and Angiology, Marienhospital Herne, University of Bochum, Germany.

View Article

Download full-text PDF

Source
January 2009

Liver TAG transiently decreases while PL n-3 and n-6 fatty acids are persistently elevated in insulin resistant mice.

Lipids 2008 Nov 2;43(11):1039-51. Epub 2008 Sep 2.

Department of Biochemistry and Molecular Biology II, University Medical Center, 20246, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11745-008-3220-3DOI Listing
November 2008

Loss of diastolic time as a mechanism of exercise-induced diastolic dysfunction in dilated cardiomyopathy.

Am Heart J 2008 Jun 19;155(6):1013-9. Epub 2008 Mar 19.

Department of Cardiology and Angiology, University of Bochum, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ahj.2008.01.027DOI Listing
June 2008

Impact of irrigated energy application on the right coronary artery hemodynamics: FFR measurement in patients who underwent ablation of common type atrial flutter.

J Interv Card Electrophysiol 2008 Jan 1;21(1):35-42. Epub 2008 Feb 1.

Department of Cardiology and Angiology, Ruhr-University Bochum/Germany, Bochum, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10840-007-9188-8DOI Listing
January 2008

Quality of life and occurrence of atrial fibrillation in long-term follow-up of common type atrial flutter ablation: ablation with irrigated 5 mm tip and conventional 8 mm tip electrodes.

Clin Res Cardiol 2007 Nov 31;96(11):794-802. Epub 2007 Aug 31.

Medizinische Klinik II, Schwerpunkte Kardiologie und Angiologie Ruhr-Universität Bochum, Hölkeskampring 40, 44625, Herne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00392-007-0559-zDOI Listing
November 2007

[Disproportionate shortening of left ventricular diastolic duration in patients with dilated cardiomyopathy].

Med Klin (Munich) 2007 Sep;102(9):707-13

Medizinische Klinik II (Schwerpunkte Kardiologie und Angiologie), Marienhospital Herne, Ruhr-Universität, Bochum.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00063-007-1089-1DOI Listing
September 2007

NMR studies of the fifth transmembrane segment of sarcoplasmic reticulum Ca2+-ATPase reveals a hinge close to the Ca2+-ligating residues.

FEBS Lett 2003 Jun;544(1-3):50-6

Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology, University of Aarhus, Langelandsgade 140, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0014-5793(03)00448-4DOI Listing
June 2003

Optimizing delays in the MBOB, broadband HMBC, and broadband XLOC NMR pulse sequences.

J Magn Reson 2002 Jun;156(2):282-94

Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark.

View Article

Download full-text PDF

Source
June 2002