Publications by authors named "Axel Grothey"

100Publications

A new prognostic and predictive tool for shared decision making in stage III colon cancer.

Eur J Cancer 2020 Oct 3;138:182-188. Epub 2020 Sep 3.

Unit of Clinical Epidemiology, Ospedale Policlinico San Martino - IRCCS, Genoa, Italy.

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http://dx.doi.org/10.1016/j.ejca.2020.07.031DOI Listing
October 2020

The Mechanism of Action of Regorafenib in Colorectal Cancer: Q&A.

Clin Adv Hematol Oncol 2019 08;17 Suppl 12(8):16-19

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Japan; Kashiwa, Japan.

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August 2019

Insights Into the Mechanism of Action of Regorafenib in Colorectal Cancer.

Authors:
Axel Grothey

Clin Adv Hematol Oncol 2019 Aug;17 Suppl 12(8):2-4

West Cancer Center and Research Institute, OneOncology, Germantown, Tennessee.

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August 2019

The Mechanism of Action of Regorafenib in Colorectal Cancer: A Guide for the Community Physician.

Clin Adv Hematol Oncol 2019 Aug;17 Suppl 12(8):1-19

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Japan; Kashiwa, Japan.

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August 2019

EGFR inhibition in colorectal cancer with liver metastasis.

Authors:
Axel Grothey

Clin Adv Hematol Oncol 2020 Jun;18(6):319-321

GI Oncology Research, West Cancer Center and Research Institute, Germantown, Tennessee.

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June 2020

Efficacy of Immunotherapy in Microsatellite-Stable or Mismatch Repair Proficient Colorectal Cancer-Fact or Fiction?

JAMA Oncol 2020 Jun;6(6):823-824

West Cancer Center and Research Institute, OneOncology, Germantown, Tennessee.

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http://dx.doi.org/10.1001/jamaoncol.2020.0504DOI Listing
June 2020

In Reply.

Oncologist 2020 May 7. Epub 2020 May 7.

Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.

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http://dx.doi.org/10.1634/theoncologist.2020-0329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267302PMC
May 2020

Evolving role of regorafenib for the treatment of advanced cancers.

Cancer Treat Rev 2020 Jun 20;86:101993. Epub 2020 Feb 20.

BCLC Group, Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBEREHD, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ctrv.2020.101993DOI Listing
June 2020

Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer. Reply.

N Engl J Med 2020 02;382(9):877-878

Vall d'Hebron Institute of Oncology, Barcelona, Spain

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http://dx.doi.org/10.1056/NEJMc1915676DOI Listing
February 2020

EGFR antibodies in resectable metastatic colorectal liver metastasis: more harm than benefit?

Lancet Oncol 2020 03 31;21(3):324-326. Epub 2020 Jan 31.

West Cancer Center and Research Institute, Germantown, TN, USA.

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http://dx.doi.org/10.1016/S1470-2045(20)30003-6DOI Listing
March 2020

Missing tumor measurement (TM) data in the search for alternative TM-based endpoints in cancer clinical trials.

Contemp Clin Trials Commun 2020 Mar 22;17:100492. Epub 2019 Nov 22.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.conctc.2019.100492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909186PMC
March 2020

Molecular Analyses of Left- and Right-Sided Tumors in Adolescents and Young Adults with Colorectal Cancer.

Oncologist 2020 05 17;25(5):404-413. Epub 2019 Dec 17.

Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1634/theoncologist.2019-0552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216442PMC
May 2020

Sequencing beyond the second-line setting in metastatic colorectal cancer: further observations.

Clin Adv Hematol Oncol 2019 Mar;17 Suppl 7(3):16-18

Mayo Clinic Cancer Center, Mayo Clinic, Phoenix, Arizona.

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March 2019

Management of patients with relapsed/refractory metastatic colorectal cancer.

Authors:
Axel Grothey

Clin Adv Hematol Oncol 2019 Mar;17 Suppl 7(3):14-16

West Cancer Center, University of Tennessee, Memphis, Tennessee.

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March 2019

Sequencing beyond the second-line setting in metastatic colorectal cancer.

Clin Adv Hematol Oncol 2019 Mar;17 Suppl 7(3):1-19

Mayo Clinic Cancer Center, Mayo Clinic, Phoenix, Arizona.

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March 2019

Encorafenib, Binimetinib, and Cetuximab in V600E-Mutated Colorectal Cancer.

N Engl J Med 2019 10 30;381(17):1632-1643. Epub 2019 Sep 30.

From the University of Texas M.D. Anderson Cancer Center, Houston (S.K., V.M.); West Cancer Center and Research Institute, OneOncology, Germantown, TN (A. Grothey); Memorial Sloan Kettering Cancer Center, New York (R.Y., A.K.); University Hospital Gasthuisberg and University of Leuven, Leuven, Belgium (E.V.C., J. Dekervel); the Peter MacCallum Cancer Centre, Melbourne, VIC, Australia (J. Desai, C.G.); National Cancer Center Hospital East, Kashiwa, Japan (T.Y.); Hammersmith Hospital, Division of Cancer, Imperial College London (H.W.), and the Sarah Cannon Research Institute and University College London Cancer Institute (H.-T.A.), London, and the Christie NHS Foundation Trust/National Institute for Health Research Manchester Biomedical Research Centre, Manchester (M.B.) - all in the United Kingdom; the University of Campania Luigi Vanvitelli, Naples (F.C.), and Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico, Padua (F.L., S.L.) - both in Italy; Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea (Y.S.H., T.-W.K.); the Netherlands Cancer Institute, Amsterdam (N.S., J.H.M.S.); Oslo University Hospital, Oslo (T.K.G.); Hospital Gregorio Marañón, Madrid (P.G.-A., A.C.F.), and Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, UVic, IOB-Quiron, Barcelona (E.E., J.T.) - both in Spain; Odense University Hospital, Odense, Denmark (P.P., L.S.T.); Pavlov First St. Petersburg State Medical University, St. Petersburg, Russia (S.O.); and Array BioPharma, Boulder, CO (A. Gollerkeri, C.K., K.M., M.P., J.C.-B., L.A., V.S.).

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http://dx.doi.org/10.1056/NEJMoa1908075DOI Listing
October 2019

Case series of dabrafenib-trametinib-induced pyrexia successfully treated with colchicine.

Support Care Cancer 2019 Oct 14;27(10):3869-3875. Epub 2019 Feb 14.

Department of Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s00520-019-4654-2DOI Listing
October 2019

Impact of primary tumour location on efficacy of bevacizumab plus chemotherapy in metastatic colorectal cancer.

Br J Cancer 2018 12 29;119(12):1451-1455. Epub 2018 Nov 29.

University of Southern California, Norris Comprehensive Cancer Center, Keck School of Medicine, 1441 Eastlake Ave, Los Angeles, CA, 90033, USA.

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http://www.nature.com/articles/s41416-018-0304-6
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http://dx.doi.org/10.1038/s41416-018-0304-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288128PMC
December 2018

Echocardiographic Assessment for the Detection of Cardiotoxicity Due to Vascular Endothelial Growth Factor Inhibitor Therapy in Metastatic Renal Cell and Colorectal Cancers.

J Am Soc Echocardiogr 2019 02 17;32(2):267-276. Epub 2018 Nov 17.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota; Division of Cardiology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.echo.2018.09.019DOI Listing
February 2019

Circulating Tumor DNA-Defined Minimal Residual Disease in Solid Tumors: Opportunities to Accelerate the Development of Adjuvant Therapies.

J Clin Oncol 2018 Oct 30:JCO2018789032. Epub 2018 Oct 30.

Arvind Dasari, The University of Texas MD Anderson Cancer Center, Houston, TX; Axel Grothey, The University of Tennessee West Cancer Center, Memphis, TN; and Scott Kopetz, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2018.78.9032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286158PMC
October 2018

Duration of Adjuvant Chemotherapy for Stage III Colon Cancer.

N Engl J Med 2018 07;379(4):396-397

Mayo Clinic, Rochester MN

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http://dx.doi.org/10.1056/NEJMc1805498DOI Listing
July 2018

5-fluorouracil and cardiotoxicity: a review.

Ther Adv Med Oncol 2018 18;10:1758835918780140. Epub 2018 Jun 18.

Department of Medical Oncology, Mayo College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1177/1758835918780140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024329PMC
June 2018

Optimizing Adjuvant Therapy for Localized Colon Cancer and Treatment Selection in Advanced Colorectal Cancer.

J Natl Compr Canc Netw 2018 05;16(5S):611-615

Presented by Axel Grothey, MD, Mayo Clinic Cancer Center, Phoenix, Arizona, and Alan P. Venook, MD, University of California, San Francisco, San Francisco, California.

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http://www.jnccn.org/lookup/doi/10.6004/jnccn.2018.0038
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http://dx.doi.org/10.6004/jnccn.2018.0038DOI Listing
May 2018

Chemotherapy-Induced Neutropenia as a Prognostic and Predictive Marker of Outcomes in Solid-Tumor Patients.

Drugs 2018 May;78(7):737-745

Division of Medical Oncology, College of Medicine/Oncology, Mayo Clinic, Gonda 10, 200 First St SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s40265-018-0909-3DOI Listing
May 2018

Highlights in metastatic colorectal cancer from the 2018 American Society of Clinical Oncology Gastrointestinal Cancers Symposium: commentary.

Authors:
Axel Grothey

Clin Adv Hematol Oncol 2018 Mar;16 Suppl 6(3):20-23

Mayo Clinic, Rochester, Minnesota.

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March 2018

Duration of Adjuvant Chemotherapy for Stage III Colon Cancer.

N Engl J Med 2018 Mar;378(13):1177-1188

From the Divisions of Medical Oncology (A.G.) and Biomedical Statistics and Informatics (Q.S., J.P.M., L.A.R., D.J.S.), Mayo Clinic, Rochester, MN; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Martino-IST, Genoa (A.F. Sobrero), Ospedale Papa Giovanni XXIII, Bergamo (R.L.), and IRCCS Mario Negri Institute for Pharmacological Research, Milan (V.T.) - all in Italy; Karmanos Cancer Institute, Wayne State University, Detroit (A.F. Shields); National Cancer Center Hospital East, Chiba (T. Yoshino), Yokohama City University School of Medicine, Yokohama (T. Yamanaka), and the University of Tokyo, Tokyo (T.W.) - all in Japan; the Institute of Cancer Sciences, University of Glasgow, Glasgow (J.P.), the University of Oxford, Oxford (R.K.), Christie Hospital, Manchester (M.S.), and University Hospital Southampton, Southampton (T.I.) - all in the United Kingdom; Hôpital Européen Georges-Pompidou, Sorbonne Paris Cite/Paris Descartes University (J.T.), and Saint-Antoine Hospital and Sorbonne Universités, Pierre and Marie Curie University-Paris 6 (T.A.), Paris, and Methodology and Quality of Life Unit, INSERM Unité 1098, Besançon (D.V.) - all in France; the Department of Medical Oncology, University Hospital of Heraklion, Faculty of Medicine, University of Crete, Heraklion (J.S.), and Bioclinic Thessaloniki, Thessaloniki (I.B.) - both in Greece; Dana-Farber Cancer Institute, Boston (J.A.M.); and Duke Cancer Institute, Durham, NC (D.N.).

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http://dx.doi.org/10.1056/NEJMoa1713709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426127PMC
March 2018

Combining Survival and Toxicity Effect Sizes from Clinical Trials: NCCTG 89-20-52 (Alliance).

Int J Stat Med Res 2018 16;7(4):137-146. Epub 2018 Nov 16.

Division of Biomedical Statistics and Bioinformatics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.6000/1929-6029.2018.07.04.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686677PMC
November 2018

Leptomeningeal Carcinomatosis in Colorectal Cancer: The Mayo Clinic Experience.

Clin Colorectal Cancer 2018 06 21;17(2):e183-e187. Epub 2017 Nov 21.

Division of Medical Oncology, Mayo Clinic Rochester, Rochester, MN.

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http://dx.doi.org/10.1016/j.clcc.2017.11.003DOI Listing
June 2018

Continued disappointments with targeted agents in first-line therapy of advanced gastric cancers.

Lancet Oncol 2017 11 25;18(11):1427-1428. Epub 2017 Sep 25.

Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30714-3DOI Listing
November 2017

Napabucasin: An Update on the First-in-Class Cancer Stemness Inhibitor.

Drugs 2017 Jul;77(10):1091-1103

Department of Medical Oncology, Mayo Clinic Rochester, 200 First Street NW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s40265-017-0759-4DOI Listing
July 2017

BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer.

J Clin Oncol 2017 Aug 9;35(23):2624-2630. Epub 2017 May 9.

Jeremy C. Jones, Lindsay A. Renfro, Ben Y. Zhang, Pashtoon M. Kasi, Jesse S. Voss, Alexis D. Leal, Joleen M. Hubbard, Benjamin R. Kipp, Robert R. McWilliams, and Axel Grothey, Mayo Clinic, Rochester, MN; Humaid O. Al-Shamsi, Scott Kopetz, and Robert A. Wolff, The University of Texas MD Anderson Cancer Center, Houston, TX; and Alexa B. Schrock, Andrew Rankin, James Sun, Jeffrey Ross, and Siraj M. Ali, Foundation Medicine, Cambridge, MA.

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http://ascopubs.org/doi/10.1200/JCO.2016.71.4394
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http://dx.doi.org/10.1200/JCO.2016.71.4394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549454PMC
August 2017

Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancérologie Digestive Database.

J Clin Oncol 2017 Jun 17;35(17):1929-1937. Epub 2017 Apr 17.

Lindsay A. Renfro, Axel Grothey, and Daniel J. Sargent, Mayo Clinic, Rochester, MN; Richard M. Goldberg, The Ohio State University, Columbus, OH; Alberto Sobrero, Ospedale San Martino, Genoa; Alfredo Falcone, University Hospital of Pisa, Pisa, Italy; Richard Adams, Cardiff University, Cardiff; Matthew T. Seymour, St James's Hospital and University of Leeds, Leeds, United Kingdom; Volker Heinemann, University of Munich, Munich; Hans-Joachim Schmoll, University Clinic Halle (Saale), Halle; Rainer Porschen, Klinikum Bremen-Ost Klinik für Innere Medizin, Bremen; Carsten Bokemeyer, University Hospital, Hamburg-Eppendorf, Germany; Jean-Yves Douillard, Centre René Gauducheau, Nantes; Christophe Tournigand, University of Paris Est Creteil; Christophe Tournigand, Assistance Hopitaux Publique de Paris Henri-Mondor Hospital, Créteil; Benoist Chibaudel and Aimery de Gramont, Franco-British Institute, Levallois-Perret, France; Herbert Hurwitz, Duke University Medical Center, Durham, NC; Charles S. Fuchs; Dana-Farber Cancer Institute, Boston, MA; Eduardo Diaz-Rubio, Hospital Clínico San Carlos, Universidad Complutense, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain; Paulo M. Hoff, Hospital Sírio-Libanês and University of São Paulo, São Paulo, Brazil; Fairooz F. Kabbinavar and J. Randolph Hecht, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, CA; Niall C. Tebbutt, Austin Health, Heidelberg, Victoria, Australia; Cornelis J.A. Punt, University of Amsterdam, Amsterdam, the Netherlands; John Souglakos, University of Crete, Heraklion, Greece; Eric Van Cutsem, University Hospital Leuven, Leuven, Belgium; and Leonard Saltz, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.5771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466009PMC
June 2017

Antiangiogenic therapy for refractory colorectal cancer: current options and future strategies.

Ther Adv Med Oncol 2017 Feb 10;9(2):106-126. Epub 2016 Nov 10.

Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1177/1758834016676703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298403PMC
February 2017

European Society for Medical Oncology Copenhagen update: potential practice-changing findings.

Ther Adv Med Oncol 2017 Jan 29;9(1):4-12. Epub 2016 Dec 29.

Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1177/1758834016679105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298453PMC
January 2017

Evidence in Favor of Standard Surgical Treatment for Rectal Cancer.

JAMA Oncol 2017 07;3(7):885-886

Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1001/jamaoncol.2016.5397DOI Listing
July 2017

Role of Biologics in First-Line Treatment of Colorectal Cancer.

J Oncol Pract 2016 12;12(12):1219-1228

Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JOP.2016.018382DOI Listing
December 2016

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

Authors:
Christian Dittrich Michael Kosty Svetlana Jezdic Doug Pyle Rossana Berardi Jonas Bergh Nagi El-Saghir Jean-Pierre Lotz Pia Österlund Nicholas Pavlidis Gunta Purkalne Ahmad Awada Susana Banerjee Smita Bhatia Jan Bogaerts Jan Buckner Fatima Cardoso Paolo Casali Edward Chu Julia Lee Close Bertrand Coiffier Roisin Connolly Sarah Coupland Luigi De Petris Maria De Santis Elisabeth G E de Vries Don S Dizon Jennifer Duff Linda R Duska Alexandru Eniu Marc Ernstoff Enriqueta Felip Martin F Fey Jill Gilbert Nicolas Girard Andor W J M Glaudemans Priya K Gopalan Axel Grothey Stephen M Hahn Diana Hanna Christian Herold Jørn Herrstedt Krisztian Homicsko Dennie V Jones Lorenz Jost Ulrich Keilholz Saad Khan Alexander Kiss Claus-Henning Köhne Rainer Kunstfeld Heinz-Josef Lenz Stuart Lichtman Lisa Licitra Thomas Lion Saskia Litière Lifang Liu Patrick J Loehrer Merry Jennifer Markham Ben Markman Marius Mayerhoefer Johannes G Meran Olivier Michielin Elizabeth Charlotte Moser Giannis Mountzios Timothy Moynihan Torsten Nielsen Yuichiro Ohe Kjell Öberg Antonio Palumbo Fedro Alessandro Peccatori Michael Pfeilstöcker Chandrajit Raut Scot C Remick Mark Robson Piotr Rutkowski Roberto Salgado Lidia Schapira Eva Schernhammer Martin Schlumberger Hans-Joachim Schmoll Lowell Schnipper Cristiana Sessa Charles L Shapiro Julie Steele Cora N Sternberg Friedrich Stiefel Florian Strasser Roger Stupp Richard Sullivan Josep Tabernero Luzia Travado Marcel Verheij Emile Voest Everett Vokes Jamie Von Roenn Jeffrey S Weber Hans Wildiers Yosef Yarden

ESMO Open 2016 29;1(5):e000097. Epub 2016 Sep 29.

Department of General Medical Oncology , University Hospitals Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1136/esmoopen-2016-000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070299PMC
September 2016

Lack of Caudal-Type Homeobox Transcription Factor 2 Expression as a Prognostic Biomarker in Metastatic Colorectal Cancer.

Clin Colorectal Cancer 2017 06 17;16(2):124-128. Epub 2016 Sep 17.

Department of Oncology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2016.09.003DOI Listing
June 2017

Further Evaluating the Benefit of Adjuvant Chemotherapy for Colon Cancer.

J Clin Oncol 2016 Oct;34(30):3711-3712

Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2016.68.4886DOI Listing
October 2016

Adverse event development in clinical oncology trials - Authors' reply.

Lancet Oncol 2016 07;17(7):e264-e265

Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/S1470-2045(16)30245-5DOI Listing
July 2016

Chemotherapy Maintenance.

Cancer J 2016 May-Jun;22(3):199-204

From the *Hematology/Oncology and †Division of Medical Oncology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/PPO.0000000000000195DOI Listing
January 2017

Adjuvant Therapy for Colon Cancer: Small Steps Toward Precision Medicine.

JAMA Oncol 2016 Sep;2(9):1133-4

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1001/jamaoncol.2016.2304DOI Listing
September 2016

Therapy: Colorectal cancer: how to teach an old drug new tricks.

Nat Rev Gastroenterol Hepatol 2016 07 25;13(7):384-5. Epub 2016 May 25.

Department of Surgical Oncology and Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77230-1402, USA.

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http://dx.doi.org/10.1038/nrgastro.2016.87DOI Listing
July 2016

Current Options for Third-Line Treatment of Metastatic Colorectal Cancer.

Clin Adv Hematol Oncol 2016 Mar;14(3 Suppl 3):1-15

University of California Irvine, Irvine, California.

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March 2016

Determinants of Early Mortality Among 37,568 Patients With Colon Cancer Who Participated in 25 Clinical Trials From the Adjuvant Colon Cancer Endpoints Database.

J Clin Oncol 2016 Apr 8;34(11):1182-9. Epub 2016 Feb 8.

Winson Y. Cheung, British Columbia Cancer Agency, Vancouver, British Columbia; Chris O'Callaghan, Queen's University, Kingston, Ontario, Canada; Lindsay A. Renfro, Axel Grothey, Steven R. Alberts, and Daniel J. Sargent, Mayo Clinic, Rochester, MN; David Kerr, University of Oxford, Oxford; Chris Twelves, University of Leeds and St James Institute of Oncology, Leeds, United Kingdom; Aimery de Gramont, Franco-British Institute, Levallois-Perret; Thierry Andre, Hospital Saint-Antoine and Pierre and Marie Curie University, Paris; Jean-Francois Seitz, La Timone Hospital, Aix-Marseille University, Marseille, France; Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY; Katherine A. Guthrie, Fred Hutchinson Cancer Center, Seattle, WA; Roberto Labianca, Ospedale Giovanni XXIII, Bergamo; Guido Francini, University of Siena, Siena, Italy; Eric Van Cutsem, University Hospital Leuven, Leuven, Belgium; Daniel G. Haller, University of Pennsylvania, Philadelphia; and Greg Yothers, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1200/JCO.2015.65.1158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933130PMC
April 2016

Adjuvant Therapy After Resection of Metastatic Colorectal Cancer: Clear Proof of Principle in This Setting.

Oncology (Williston Park) 2016 Jan;30(1):50-1, 53

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January 2016

Association between DPYD c.1129-5923 C>G/hapB3 and severe toxicity to 5-fluorouracil-based chemotherapy in stage III colon cancer patients: NCCTG N0147 (Alliance).

Pharmacogenet Genomics 2016 Mar;26(3):133-7

aDepartment of Molecular Pharmacology and Experimental Therapeutics (MPET), Mayo Clinic Cancer Center bAlliance Statistics and Data Center cDivision of Medical Oncology dDivision of Gastroenterology, Mayo Clinic, Rochester, Minnesota eDepartment of Surgery, Cancer Prevention and Control Program, University of Hawaii Cancer Center, Honolulu, Hawaii fDepartment of Medicine, Center for GI Oncology, The University of Chicago Medicine, Chicago, Illinois gDivision of Hematology Oncology, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee hSurgical Oncology Associates of South Texas, San Antonio, Texas iDepartment of Hematology Oncology, Lehigh Valley Health Network, John and Dorthy Morgan Cancer Center, Allentown, Pennsylvania jDepartment of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan kDepartment of Hematology/Oncology, Division of Medical Oncology, The Ohio State University Medical Center, Columbus, Ohio, USA lDepartment of Medicine, Division of Medical Oncology, University of British Columbia, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/FPC.0000000000000197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738010PMC
March 2016

Regorafenib in the treatment of colorectal cancer.

Expert Opin Pharmacother 2016 4;17(1):137-45. Epub 2015 Dec 4.

b Department of Medical Oncology , Mayo Clinic , Rochester , MN 55905 , USA.

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http://dx.doi.org/10.1517/14656566.2016.1118054DOI Listing
June 2016

Molecular profiling in the treatment of colorectal cancer: focus on regorafenib.

Onco Targets Ther 2015 15;8:2949-57. Epub 2015 Oct 15.

Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.2147/OTT.S79145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610887PMC
October 2015

Introduction to special issue on biomarker-based clinical trial designs in oncology.

Chin Clin Oncol 2015 Sep;4(3):28

Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.3978/j.issn.2304-3865.2015.09.05DOI Listing
September 2015

Is obesity an advantage in patients with colorectal cancer?

Expert Rev Gastroenterol Hepatol 2015 14;9(11):1339-42. Epub 2015 Sep 14.

a 1 Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1586/17474124.2015.1089170DOI Listing
August 2016

Calcium and Magnesium Use for Oxaliplatin-Induced Neuropathy: A Case Study to Assess How Quickly Evidence Translates Into Practice.

J Natl Compr Canc Netw 2015 Sep;13(9):1097-101

From the Department of Oncology, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, and Health Care Policy & Research, Mayo Clinic, Rochester, Minnesota; and Optum Labs, Cambridge, Massachusetts.

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http://dx.doi.org/10.6004/jnccn.2015.0134DOI Listing
September 2015

Regorafenib in metastatic colorectal cancer: optimal dosing and patient selection recommendations.

Authors:
Axel Grothey

Clin Adv Hematol Oncol 2015 Aug;13(8):514-7

May Clinic, Rochester, Minnesota.

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August 2015

Maintenance therapy in the treatment of metastatic colorectal cancer. Axel Grothey, MD.

Authors:
Axel Grothey

Oncology (Williston Park) 2015 Aug;29(8):560, 594

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August 2015

Evaluating Continuous Tumor Measurement-Based Metrics as Phase II Endpoints for Predicting Overall Survival.

J Natl Cancer Inst 2015 Nov 21;107(11). Epub 2015 Aug 21.

Department of Mathematics, Vassar College, Poughkeepsie, NY (MWA); Department of Biostatistics, Analytical Science, Takeda Pharmaceuticals, Deerfield, IL (XD); Department of Health Sciences Research, Mayo Clinic, Rochester, MN (JM, DJS, SJM); Biometrics and Data Management Department, Novartis Pharmaceuticals Corporation, East Hanover, NJ (YH); Department of Oncology, Mayo Clinic, Rochester, MN (AG); European Organisation for Research and Treatment of Cancer (EORTC), Brussels, Belgium (JB).

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http://jnci.oxfordjournals.org/content/107/11/djv239.full.pd
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv23
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http://dx.doi.org/10.1093/jnci/djv239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643633PMC
November 2015