Publications by authors named "Austin Kulasekararaj"

90Publications

Romiplostim in aplastic anaemia - another tool in the armamentarium.

Br J Haematol 2021 Jan 5;192(1):15-16. Epub 2020 Nov 5.

King's College Hospital NHS Foundation Trust, London, UK.

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January 2021

Regulatory cells in immune-mediated aplastic anaemia - not T but B.

Br J Haematol 2020 Aug 4;190(4):486-487. Epub 2020 Jun 4.

Department of Haematological Medicine, King's College Hospital, London, UK.

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August 2020

Secondary HLH is uncommon in severe COVID-19.

Br J Haematol 2020 09 10;190(5):e283-e285. Epub 2020 Aug 10.

Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.

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September 2020

Terminal complement inhibition dampens the inflammation during COVID-19.

Br J Haematol 2020 08 28;190(3):e141-e143. Epub 2020 Jun 28.

Department of Haematological Medicine, King's College Hospital-NHS Foundation Trust, London, UK.

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August 2020

Coombs-positive Paroxysmal Nocturnal Haemoglobinuria.

Oxf Med Case Reports 2020 Mar 30;2020(3):omz125. Epub 2020 Mar 30.

Department of Endocrinology, University College London Hospital, London NW1 2BU, UK.

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March 2020

Ravulizumab for the treatment of paroxysmal nocturnal hemoglobinuria.

Expert Opin Biol Ther 2020 03 14;20(3):227-237. Epub 2020 Feb 14.

Department of Haematological Medicine, King's College Hospital, NHS Foundation Trust and King's College, London, UK.

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March 2020

Second-Generation C5 Inhibitors for Paroxysmal Nocturnal Hemoglobinuria.

BioDrugs 2020 Apr;34(2):149-158

Department of Haematological Medicine, King's College Hospital, National Institute of Health Research/Wellcome King's Clinical Research Facility, London, SE5 9RS, UK.

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April 2020

Mechanisms and therapeutic prospects of thrombopoietin receptor agonists.

Semin Hematol 2019 10 19;56(4):262-278. Epub 2019 Oct 19.

Albert Einstein College of Medicine, New York, NY. Electronic address:

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October 2019

The Role of Real-World Evidence in UK Reimbursement: Case Study of Lenalidomide in Myelodysplastic Syndrome Deletion 5q.

Pharmacoecon Open 2019 Sep;3(3):351-358

King's College Hospital National Health Service Foundation Trust, London, UK.

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September 2019

Prognostic impact of bone marrow fibrosis and dyserythropoiesis in autoimmune hemolytic anemia.

Am J Hematol 2018 08 10;93(4):E88-E91. Epub 2018 Jan 10.

Hematology Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Milan, Italy.

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August 2018

Clonal dominance of PNH- another piece to the jigsaw.

Br J Haematol 2017 04 14;177(1):9-10. Epub 2017 Mar 14.

Department of Haematology, Kings College Hospital, London, UK.

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April 2017

Myelodysplastic syndrome can propagate from the multipotent progenitor compartment.

Haematologica 2017 01 6;102(1):e7-e10. Epub 2016 Oct 6.

Haematopoietic Stem Cell Laboratory, The Francis Crick Institute, Department of Haematological Medicine, London, UK

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January 2017

Association between Transfusion Status and Overall Survival in Patients with Myelodysplastic Syndromes: A Systematic Literature Review and Meta-Analysis.

Acta Haematol 2016 30;136(1):23-42. Epub 2016 Apr 30.

Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK.

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December 2016

CSNK1A1 mutations and isolated del(5q) abnormality in myelodysplastic syndrome: a retrospective mutational analysis.

Lancet Haematol 2015 May 6;2(5):e212-21. Epub 2015 May 6.

Department of Haematological Medicine, King's College London School of Medicine, Rayne Institute, King's College London, London, UK; Department of Haematology, King's College Hospital, King's College London, London, UK. Electronic address:

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May 2015

Sweet spot for cyclophosphamide: a balancing act.

Lancet Haematol 2015 Sep 2;2(9):e350-1. Epub 2015 Sep 2.

Department of Haematological Medicine, Kings College Hospital and Kings College London, Denmark Hill, London SE5 9RS, UK.

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September 2015

SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment.

Nat Commun 2015 Dec 8;6:10004. Epub 2015 Dec 8.

Department of Haematological Medicine, King's College London School of Medicine, London SE5 9NU, UK.

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December 2015

Tissue Iron Distribution Assessed by MRI in Patients with Iron Loading Anemias.

PLoS One 2015 25;10(9):e0139220. Epub 2015 Sep 25.

King's College London, Faculty of Life Sciences & Medicine, Molecular Haematology, London, United Kingdom; King's College Hospital NHS Foundation Trust, Department of Haematology, London, United Kingdom; NHLB/ NIH, Sickle Cell Branch, Bethesda, MD 20892, United States of America.

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May 2016

Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria.

N Engl J Med 2015 Sep;373(11):1032-9

From Department of Haematology, St. James's University Hospital, Leeds (R.J.K., A.H.), and Haematological Medicine, Kings College Hospital, London (A.K.) - both in the United Kingdom; University of Ulm and German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen, Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Ulm (B.H., H.S.), and Department of Hematology, University Hospital of Essen, Essen (A.R.) - both in Germany; PNH Subcommittee of the Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation, Leiden (B.H., A.K., A.M.R., L.T., H.S., R.P.L.), and Radboud University Medical Center, Nijmegen (P.M.) - both in the Netherlands; Department of Clinical Haematology, the Royal Melbourne Hospital and University of Melbourne, Parkville, VIC, Australia (J.S.); Department of Hematology, University Hospital, Rennes (S.G.), Clinical Immunology, Department of Internal Medicine, University Hospital of Lille, Lille (L.T.), and Assistance Publique-Hôpitaux de Paris, Service d'Hématologie-Greffe, Hôpital Saint-Louis, University Paris Diderot, Sorbonne Paris Cité, Centre de Référence Aplasie Médullaire-HPN, and Filière de Santé Maladie Rare Immuno-Hématologique (MARIH), Paris (R.P.L.) - all in France; Jane Anne Nohl Division of Hematology, Keck School of Medicine of University of Southern California, Los Angeles (I.C.W.); Department of Hematology, Helsinki University Central Hospital, Helsinki (E.A.); Hematology, Department of Clinical Medicine and Surgery, Federico II, University of Naples, Naples, Italy (A.M.R.); Hematology and Thromboembolism, McMaster University, Hamilton, ON, Canada (C.J.P.); and ICON Clinical Research, San Francisco (M.P.T.).

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September 2015

Chronic relapsing remitting Sweet syndrome--a harbinger of myelodysplastic syndrome.

Br J Haematol 2015 Sep 12;170(5):649-56. Epub 2015 May 12.

Department of Dermatology, King's College Hospital, London, UK.

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September 2015

Successful treatment of aplastic anaemia associated with HIV infection with eltrombopag: implications for a possible immunomodulatory role.

AIDS 2014 Nov;28(18):2786-8

aDepartment of Haematological Medicine, King's College Hospital bKing's College London, London cHIV Medicine Brighton & Sussex University Hospitals NHS Trust, Brighton, UK.

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November 2014

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome.

Blood 2014 Oct 18;124(17):2698-704. Epub 2014 Aug 18.

Department of Haematological Medicine, King's College London School of Medicine, London, United Kingdom; and Department of Haematology, King's College Hospital, London, United Kingdom.

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October 2014

Nonmyeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia.

Biol Blood Marrow Transplant 2014 Nov 10;20(11):1711-6. Epub 2014 Jul 10.

Department of Hematological Medicine, King's College Hospital, London, United Kingdom; Department of Haematological Medicine, King's College London, London, United Kingdom. Electronic address:

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November 2014

Aplastic anaemia.

Hematology 2014 Jan 25;19(1):60-1. Epub 2013 Nov 25.

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January 2014

Management of the refractory aplastic anemia patient: what are the options?

Hematology Am Soc Hematol Educ Program 2013 ;2013:87-94

1King's College Hospital and.

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December 2014

Haematopoietic stem cell transplantation for acquired aplastic anaemia.

Curr Opin Hematol 2013 Nov;20(6):515-20

aHaematology Department, Kings College Hospital bKings College London, London, UK.

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November 2013

Management of the refractory aplastic anemia patient: what are the options?

Blood 2013 Nov 19;122(22):3561-7. Epub 2013 Sep 19.

King's College Hospital, and.

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November 2013

Recent advances in understanding the molecular pathogenesis of myelodysplastic syndromes.

Br J Haematol 2013 Sep 19;162(5):587-605. Epub 2013 Jul 19.

Department of Haematological Medicine, King's College London School of Medicine, London, UK.

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September 2013

Utility of peripheral blood for cytogenetic and mutation analysis in myelodysplastic syndrome.

Blood 2013 Jul 12;122(4):567-70. Epub 2013 Jun 12.

Department of Haematological Medicine, King's College London, Rayne Institute, London, United Kingdom.

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July 2013

Bilateral retinal vasculopathy associated with autosomal dominant dyskeratosis congenita.

Eur J Ophthalmol 2013 Sep-Oct;23(5):772-5. Epub 2013 May 3.

Medical Retina Department, Moorfields Eye Hospital NHS Foundation Trust, London, UK.

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February 2014

Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies.

Haematologica 2013 Sep 24;98(9):1397-406. Epub 2013 Jan 24.

Department of Haematological Medicine, King’s College London, Leukaemia Sciences Laboratories, The Rayne Institute, Denmark Hill Campus, London UK.

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September 2013

SnapShot: Acute myeloid leukemia.

Cancer Cell 2012 Nov;22(5):698-698.e1

Department of Haematological Medicine, King's College London, London SE5 9NU, UK.

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November 2012

The non-transplant treatment of myelodysplastic syndromes-what's on the horizon?

Semin Hematol 2012 Oct;49(4):350-60

Department of Haematological Medicine, King's College London School of Medicine, London, UK.

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October 2012

TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression.

J Clin Oncol 2011 May 25;29(15):1971-9. Epub 2011 Apr 25.

Center for Experimental Hematology M54, Karolinska Institutet, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.

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May 2011

Portacaths are safe for long-term regular blood transfusion in children with sickle cell anaemia.

Arch Dis Child 2011 Nov 6;96(11):1082-4. Epub 2010 Jul 6.

Department of Paediatric Haematology, King's College London School of Medicine, King's College Hospital, Denmark Hill, London SE5 9RS, UK.

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November 2011