Publications by authors named "Austin G Smith"

23Publications

Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production.

J Org Chem 2019 04 22;84(8):4615-4628. Epub 2019 Mar 22.

Chemical Development , Boehringer Ingelheim Pharmaceuticals , Ridgefield , Connecticut 06877 , United States.

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http://dx.doi.org/10.1021/acs.joc.8b03001DOI Listing
April 2019

Development of a Commercial Process To Prepare AMG 232 Using a Green Ozonolysis-Pinnick Tandem Transformation.

J Org Chem 2019 04 2;84(8):4763-4779. Epub 2019 Jan 2.

Pivotal Drug Substance Technologies , Amgen Inc ., One Amgen Center Drive , Thousand Oaks , California 91320 , United States.

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http://dx.doi.org/10.1021/acs.joc.8b02390DOI Listing
April 2019

Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells.

Biol Open 2012 Jan 1;1(1):58-65. Epub 2011 Nov 1.

Wellcome Trust Centre for Stem Cell Research, University of Cambridge , Tennis Court Road, Cambridge CB2 1QN , UK ; Department of Biochemistry, University of Cambridge , Tennis Court Road, Cambridge CB2 1QN , UK.

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http://dx.doi.org/10.1242/bio.2011029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507162PMC
January 2012

Rhodium-catalyzed enantioselective vinylogous addition of enol ethers to vinyldiazoacetates.

J Am Chem Soc 2012 Nov 29;134(44):18241-4. Epub 2012 Oct 29.

Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1021/ja3092399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549400PMC
November 2012

Polarity inversion of donor-acceptor cyclopropanes: disubstituted δ-lactones via enantioselective iridium catalysis.

J Am Chem Soc 2011 Nov 31;133(46):18618-21. Epub 2011 Oct 31.

Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA.

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http://pubs.acs.org/doi/abs/10.1021/ja2090993
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http://dx.doi.org/10.1021/ja2090993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218199PMC
November 2011

Cyclopropane-aldehyde annulations at quaternary donor sites: stereoselective access to highly substituted tetrahydrofurans.

Org Lett 2011 Apr 11;13(8):1996-9. Epub 2011 Mar 11.

Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, USA.

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http://dx.doi.org/10.1021/ol200395eDOI Listing
April 2011

Imaging-based chemical screens using normal and glioma-derived neural stem cells.

Biochem Soc Trans 2010 Aug;38(4):1067-71

Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.

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http://dx.doi.org/10.1042/BST0381067DOI Listing
August 2010

The ground state of pluripotency.

Biochem Soc Trans 2010 Aug;38(4):1027-32

Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.

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http://dx.doi.org/10.1042/BST0381027DOI Listing
August 2010

Dynamic kinetic asymmetric synthesis of substituted pyrrolidines from racemic cyclopropanes and aldimines: reaction development and mechanistic insights.

J Am Chem Soc 2010 Jul;132(28):9688-92

Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, USA.

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http://dx.doi.org/10.1021/ja1032277DOI Listing
July 2010

Lewis acid-promoted Friedel-Crafts alkylation reactions with alpha-ketophosphate electrophiles.

Org Lett 2010 Apr;12(8):1784-7

Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, USA.

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http://dx.doi.org/10.1021/ol100410kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852482PMC
April 2010

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors.

FASEB J 2010 Mar 22;24(3):700-11. Epub 2009 Oct 22.

Klinikum rechts der Isar and Deutsches Herzzentrum, Technical University of Munich, I. Medical Department, Molecular Cardiology, Ismaninger Strasse 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1096/fj.09-139477DOI Listing
March 2010

Neuroepithelial cells supply an initial transient wave of MSC differentiation.

Cell 2007 Jun;129(7):1377-88

Laboratory for Stem Cell Biology, Riken Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, 650-0047, Japan.

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http://dx.doi.org/10.1016/j.cell.2007.04.028DOI Listing
June 2007

Notch promotes neural lineage entry by pluripotent embryonic stem cells.

PLoS Biol 2006 May 11;4(5):e121. Epub 2006 Apr 11.

Centre Development in Stem Cell Biology, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.0040121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431581PMC
May 2006

Osteogenic and chondrogenic differentiation of embryonic stem cells in response to specific growth factors.

Bone 2005 May 24;36(5):758-69. Epub 2005 Mar 24.

Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh EH9 3JQ, United Kingdom.

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http://dx.doi.org/10.1016/j.bone.2004.07.019DOI Listing
May 2005

SoxB transcription factors specify neuroectodermal lineage choice in ES cells.

Mol Cell Neurosci 2004 Nov;27(3):332-42

Institute for Stem Cell Research, University of Edinburgh, Edinburgh, EH9 3JQ, United Kingdom.

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http://dx.doi.org/10.1016/j.mcn.2004.08.002DOI Listing
November 2004

Defined conditions for neural commitment and differentiation.

Methods Enzymol 2003 ;365:327-41

Institute for Stem Cell Research, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, Scotland, EH9 3JQ, UK.

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http://dx.doi.org/10.1016/s0076-6879(03)65023-8DOI Listing
January 2004

An unpaired mouse centromere passes consistently through male meiosis and does not significantly compromise spermatogenesis.

Chromosoma 2003 Dec 8;112(4):183-9. Epub 2003 Nov 8.

Institute for Stem Cell Research, The University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, EH9 3JQ, UK.

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http://dx.doi.org/10.1007/s00412-003-0260-6DOI Listing
December 2003

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.

Nat Biotechnol 2003 Apr 10;21(4):443-7. Epub 2003 Mar 10.

Biotec, Technische Universität Dresden, GmbH, c/o Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstr. 108, Dresden, Germany 01307.

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http://dx.doi.org/10.1038/nbt804DOI Listing
April 2003

Changing potency by spontaneous fusion.

Nature 2002 Apr 13;416(6880):545-8. Epub 2002 Mar 13.

Centre for Genome Research, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh EH9 3JQ, UK.

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http://dx.doi.org/10.1038/nature729DOI Listing
April 2002

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

Mol Cell Biol 2002 Mar;22(5):1526-36

Stem Cell Regulation Research, Area of Molecular Therapeutics, Course of Advanced Medicine, Osaka University Graduate School of Medicine, Suita C, Osaka 565-0871, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134688PMC
http://dx.doi.org/10.1128/mcb.22.5.1526-1536.2002DOI Listing
March 2002