Aurelien Marabelle

Aurelien Marabelle

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Aurelien Marabelle

Publications by authors named "Aurelien Marabelle"

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Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies.

Nat Rev Clin Oncol 2019 Oct 8. Epub 2019 Oct 8.

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1038/s41571-019-0272-7DOI Listing
October 2019

Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3 Regulatory T Cells (Tregs) in Human Cancers-Letter.

Clin Cancer Res 2019 Jun 4;25(11):3468. Epub 2018 Dec 4.

INSERM U1015, Gustave Roussy, Université Paris-Saclay, Villejuif, France.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-3740DOI Listing
June 2019

Prevalence and Clinical Patterns of Ocular Complications Associated With Anti-PD-1/PD-L1 Anticancer Immunotherapy.

Am J Ophthalmol 2019 Jun 15;202:109-117. Epub 2019 Feb 15.

Service d'Ophtalmologie, DHU Vision & Handicaps, Centre de référence pour les maladies rares en ophtalmologie (OPHTARA), Hôpital Bicêtre, Assistance Publique Hôpitaux de Paris, Le Kremlin-Bicêtre, France; Université Paris-Sud, Le Kremlin-Bicêtre, France; Immunology of Viral Infections and Autoimmune Diseases, INSERM U1184, Le Kremlin-Bicêtre, France; Department of Immunology of Viral and Auto-immune Disease, UMR1184, CEA, CEA, DSV/iMETI, IDMIT, Fontenay-aux-Roses, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajo.2019.02.012DOI Listing
June 2019

Pathogen Molecular Pattern Receptor Agonists: Treating Cancer by Mimicking Infection.

Clin Cancer Res 2019 May 23. Epub 2019 May 23.

Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1800DOI Listing
May 2019

Reply to: "Acute liver failure due to immune-mediated hepatitis successfully managed with plasma exchange: New settings call for new treatment strategies?"

J Hepatol 2019 Mar 5;70(3):566-567. Epub 2018 Dec 5.

AP-HP Hôpital Paul Brousse, Centre Hépato-Biliaire, Univ Paris-Sud, UMR-S 1193, Université Paris-Saclay Villejuif, DHU Hepatinov, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.11.016DOI Listing
March 2019

Stromal lymphocyte infiltration is associated with tumour invasion depth but is not prognostic in high-grade T1 bladder cancer.

Eur J Cancer 2019 Feb 14;108:111-119. Epub 2019 Jan 14.

Department of Urology, Hôpital Foch, Université Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Suresnes, France.

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http://dx.doi.org/10.1016/j.ejca.2018.12.010DOI Listing
February 2019

PD-Loma: a cancer entity with a shared sensitivity to the PD-1/PD-L1 pathway blockade.

Br J Cancer 2019 01 9;120(1):3-5. Epub 2018 Nov 9.

Département d'Innovation Thérapeutique et d'Essais Précoces, Gustave Roussy, Université Paris-Saclay, Villejuif, F-94805, France.

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http://www.nature.com/articles/s41416-018-0294-4
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http://dx.doi.org/10.1038/s41416-018-0294-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325162PMC
January 2019

Haematological immune-related adverse events induced by anti-PD-1 or anti-PD-L1 immunotherapy: a descriptive observational study.

Lancet Haematol 2019 Jan 4;6(1):e48-e57. Epub 2018 Dec 4.

Service de Médecine Interne and Immunologie Clinique, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France; Université Paris Sud, Centre de Recherche en Immunologie des Infections Virales et des Maladies Auto-Immunes, INSERM, Le Kremlin-Bicêtre, France; Division d'Immunovirologie, Commissariat à l'Energie Atomique et aux Energies Alternatives, Fontenay-aux-Roses, France.

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http://dx.doi.org/10.1016/S2352-3026(18)30175-3DOI Listing
January 2019

Reply to: "Incidence of grade 3-4 liver injury under immune checkpoints inhibitors: A retrospective study".

J Hepatol 2018 12 5;69(6):1397-1398. Epub 2018 Oct 5.

AP-HP Hôpital Paul-Brousse, Centre Hépato-Biliaire, Univ Paris-Sud, UMR-S 1193, Université Paris-Saclay Villejuif, DHU Hepatinov, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.09.006DOI Listing
December 2018

Hyperprogressive disease: recognizing a novel pattern to improve patient management.

Nat Rev Clin Oncol 2018 12;15(12):748-762

Département d'Innovation Thérapeutique et des Essais Précoces (DITEP), Gustave Roussy, Université Paris Saclay, Villejuif, France.

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http://www.nature.com/articles/s41571-018-0111-2
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http://dx.doi.org/10.1038/s41571-018-0111-2DOI Listing
December 2018

Autres immunothérapies.

Bull Cancer 2018 Dec;105 Suppl 1:S121-S131

Gustave Roussy, Université Paris-Saclay, département d'innovation thérapeutique et d'essais précoces, Villejuif, F-94805, France; Inserm U1015, Gustave Roussy, Villejuif, F-94805, France.

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http://dx.doi.org/10.1016/S0007-4551(18)30397-7DOI Listing
December 2018

Reply to: "Mortality due to immunotherapy related hepatitis".

J Hepatol 2018 10 7;69(4):978-979. Epub 2018 Aug 7.

AP-HP Hôpital Paul-Brousse, Centre Hépato-Biliaire, Villejuif, F-94800, France, DHU Hepatinov, Villejuif, France; Inserm, Unité 1193, Villejuif, Université Paris-Saclay, F-94800, France; Univ Paris-Sud, UMR-S 1193, Université Paris-Saclay, Villejuif, F-94800, France; Univ Paris-Sud, UMR-S 1193, Université Paris-Saclay, Villejuif, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278183226
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http://dx.doi.org/10.1016/j.jhep.2018.07.009DOI Listing
October 2018

A radiomics approach to assess tumour-infiltrating CD8 cells and response to anti-PD-1 or anti-PD-L1 immunotherapy: an imaging biomarker, retrospective multicohort study.

Lancet Oncol 2018 09 14;19(9):1180-1191. Epub 2018 Aug 14.

Gustave Roussy-CentraleSupélec-Therapanacea Centre of Artificial Intelligence in Radiation Therapy and Oncology, Gustave Roussy Cancer Campus, Villejuif, France; Radiomics Team, Molecular Radiotherapy INSERM U1030, Paris-Sud University, Gustave Roussy Cancer Campus, and University of Paris-Saclay, Villejuif, France; Department of Drug Development, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1016/S1470-2045(18)30413-3DOI Listing
September 2018

Reply to: "Immune-related hepatitis with immunotherapy: Are corticosteroids always needed?"

J Hepatol 2018 08;69(2):550-551

AP-HP Hôpital Paul-Brousse, Centre Hépato-Biliaire, INSERM, Unité 1193, Univ Paris-Sud, UMR-S 1193, Université Paris-Saclay, DHU Hepatinov, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.04.019DOI Listing
August 2018

Characterization of liver injury induced by cancer immunotherapy using immune checkpoint inhibitors.

J Hepatol 2018 06 8;68(6):1181-1190. Epub 2018 Feb 8.

AP-HP Hôpital Paul-Brousse, Centre Hépato-Biliaire; Univ Paris-Sud, UMR-S 1193, Université Paris-Saclay; Inserm, Unité 1193, Université Paris-Saclay; Hepatinov, Villejuif, F-94800, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.01.033DOI Listing
June 2018

Detection of immune-related adverse events by medical imaging in patients treated with anti-programmed cell death 1.

Eur J Cancer 2018 06 23;96:91-104. Epub 2018 Apr 23.

Department of Radiology, Gustave Roussy Cancer Campus, Villejuif, France; Université Paris-Saclay, Paris, France.

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http://dx.doi.org/10.1016/j.ejca.2018.03.006DOI Listing
June 2018

Safety and efficacy of anti-programmed death 1 antibodies in patients with cancer and pre-existing autoimmune or inflammatory disease.

Eur J Cancer 2018 03 10;91:21-29. Epub 2018 Jan 10.

Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Service de Médecine Interne et Immunologie Clinique, F-94275, Le Kremlin-Bicêtre, France; INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases, F-94276, Le Kremlin-Bicêtre, France; Université Paris Sud, UMR 1184, F-94276, Le Kremlin-Bicêtre, France; CEA, DSV/iMETI, IDMIT, F-92265, Fontenay-aux-Roses, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.12.008DOI Listing
March 2018

Kinetics and nadir of responses to immune checkpoint blockade by anti-PD1 in patients with classical Hodgkin lymphoma.

Eur J Cancer 2018 03;91:136-144

Department of Medicine Oncology, Gustave Roussy Comprehensive Cancer Center, F-94805 Villejuif, France; Gustave Roussy, Université Paris-Saclay, Département D'hématologie, Villejuif F-94805, France.

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http://dx.doi.org/10.1016/j.ejca.2017.12.015DOI Listing
March 2018

Human epidermal receptor family inhibitors in patients with ERBB3 mutated cancers: Entering the back door.

Eur J Cancer 2018 03 3;92:1-10. Epub 2018 Feb 3.

Drug Development Department, Gustave Roussy, Department of Medical Oncology, Faculté de Medicine Paris-Sud XI, Kremlin-Bicêtre, France; Gustave Roussy Department of Medical Oncology, Faculté de Medicine Paris-Sud XI, Kremlin-Bicêtre, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.12.020DOI Listing
March 2018

Hair Repigmentation With Anti-PD-1 and Anti-PD-L1 Immunotherapy: A Novel Hypothesis.

JAMA Dermatol 2018 01;154(1):113

Department of Hematology, CHU Rennes, Rennes, France.

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http://dx.doi.org/10.1001/jamadermatol.2017.4421DOI Listing
January 2018

Challenges and perspectives in the immunotherapy of Hodgkin lymphoma.

Eur J Cancer 2017 11 9;85:67-77. Epub 2017 Sep 9.

Département des Innovations Thérapeutiques et des Essais Précoces, Gustave Roussy, 114 Rue Edouard-Vaillant, F-94805 Villejuif, France; Département d'Oncologie Médicale, Institut Jules Bordet, rue Héger Bordet 1, B-1000 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.ejca.2017.08.014DOI Listing
November 2017

Late-occurring nivolumab-induced cryptogenic organising pneumonia mimicking lung progression in a patient with metastatic non-small cell lung cancer.

Eur J Cancer 2017 11 13;85:155-157. Epub 2017 Sep 13.

Drug Development Department (DITEP), Gustave Roussy, and University Paris-Sud, Villejuif, France; INSERM U981, Gustave Roussy, University Paris XI, Villejuif, France.

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http://dx.doi.org/10.1016/j.ejca.2017.07.049DOI Listing
November 2017

Baseline lymphopenia should not be used as exclusion criteria in early clinical trials investigating immune checkpoint blockers (PD-1/PD-L1 inhibitors).

Eur J Cancer 2017 10 18;84:202-211. Epub 2017 Aug 18.

Drug Development Department, Gustave Roussy Cancer Campus, 94800 Villejuif, France; Department of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94800 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.07.033DOI Listing
October 2017

Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine.

Eur J Cancer 2017 10 29;84:290-303. Epub 2017 Aug 29.

UMR8200 - CNRS, Stabilité Génétique et Oncogenèse, France; Gustave Roussy Cancer Campus, F-94805, Villejuif, France; Université Paris Saclay, Paris Sud - Orsay, F-91400, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049173114
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http://dx.doi.org/10.1016/j.ejca.2017.07.026DOI Listing
October 2017

Microenvironment-Driven Shift of Cohesion/Detachment Balance within Tumors Induces a Switch toward Metastasis in Neuroblastoma.

Cancer Cell 2017 10;32(4):427-443.e8

University of Lyon, University of Lyon 1 Claude Bernard Lyon1, NeuroMyoGene Institute, CNRS UMR5310, INSERM U1217, 16 rue Raphael Dubois, F-69000 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.09.006DOI Listing
October 2017

Prevalence of immune-related systemic adverse events in patients treated with anti-Programmed cell Death 1/anti-Programmed cell Death-Ligand 1 agents: A single-centre pharmacovigilance database analysis.

Eur J Cancer 2017 09 10;82:34-44. Epub 2017 Jul 10.

Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Service de Médecine Interne et Immunologie Clinique, F-94275 Le Kremlin-Bicêtre, France; INSERM, U1184, Immunology of Viral Infections and Autoimmune Diseases, F-94276 Le Kremlin-Bicêtre, France; Université Paris Sud, UMR 1184, F-94276 Le Kremlin-Bicêtre, France; CEA, DSV/iMETI, IDMIT, F-92265 Fontenay-aux-Roses, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.05.032DOI Listing
September 2017

iRECIST: A clarification of tumour response assessment in the immunotherapy era.

Eur J Cancer 2017 05 4;77:165-167. Epub 2017 Apr 4.

Early Drug Development Unit (DITEP), Gustave Roussy, Paris Saclay University, Villejuif, France; INSERM U1015, Gustave Roussy, Paris Saclay University, Villejuif, France.

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http://dx.doi.org/10.1016/j.ejca.2017.02.015DOI Listing
May 2017

Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1.

Clin Cancer Res 2017 04 8;23(8):1920-1928. Epub 2016 Nov 8.

Département d'Innovation Thérapeutique et des Essais Précoces (DITEP), Gustave Roussy, Université Paris Saclay, Villejuif, France.

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http://clincancerres.aacrjournals.org/content/early/2016/11/
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http://dx.doi.org/10.1158/1078-0432.CCR-16-1741DOI Listing
April 2017

JAK Mutations as Escape Mechanisms to Anti-PD-1 Therapy.

Cancer Discov 2017 02;7(2):128-130

Gustave Roussy, Université Paris-Saclay, Département d'Innovation Thérapeutique et d'Essais Précoces (DITEP), Villejuif, France.

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http://dx.doi.org/10.1158/2159-8290.CD-16-1439DOI Listing
February 2017

Turning tumour cells into antigen presenting cells: The next step to improve cancer immunotherapy?

Eur J Cancer 2016 11 15;68:134-147. Epub 2016 Oct 15.

CHU Rennes, Service Hématologie Clinique, F-35033, Rennes, France; INSERM, U917, F-35043, Rennes, France. Electronic address:

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http://www.ejcancer.com/article/S0959804916324315/pdf
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https://www.researchgate.net/publication/309184910_Turning_t
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https://linkinghub.elsevier.com/retrieve/pii/S09598049163243
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http://dx.doi.org/10.1016/j.ejca.2016.09.010DOI Listing
November 2016

Moving Immune Checkpoint Blockade in Thoracic Tumors beyond NSCLC.

J Thorac Oncol 2016 11 8;11(11):1819-1836. Epub 2016 Jun 8.

Medical Oncology Unit, University Hospital of Parma, Parma, Italy.

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http://dx.doi.org/10.1016/j.jtho.2016.05.027DOI Listing
November 2016

Abscopal effect in a Hodgkin lymphoma patient treated by an anti-programmed death 1 antibody.

Eur J Cancer 2016 10 18;66:91-4. Epub 2016 Aug 18.

Drug Development Department, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France; Department of Radiation Oncology, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France; INSERM U1030, Molecular Radiotherapy, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France; Univ Paris Sud, Université Paris-Saclay, F-94270, Le Kremlin-Bicêtre, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.06.017DOI Listing
October 2016

Mutational Landscape and Sensitivity to Immune Checkpoint Blockers.

Clin Cancer Res 2016 Sep 7;22(17):4309-21. Epub 2016 Jul 7.

Faculté de Médicine, Université Paris Saclay, Université Paris-Sud, Le Kremlin Bicêtre, France. Inserm Unit U981, Gustave Roussy, Villejuif, France. DITEP (Département d'Innovations Thérapeutiques et Essais Précoces), Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0903DOI Listing
September 2016

Rapid and objective CT scan prognostic scoring identifies metastatic patients with long-term clinical benefit on anti-PD-1/-L1 therapy.

Eur J Cancer 2016 09 21;65:33-42. Epub 2016 Jul 21.

Université Paris-Saclay, Paris, France; Gustave Roussy, Université Paris-Saclay, Drug Development Department, Villejuif, F-94805, France; Gustave Roussy, Université Paris-Saclay, INSERM U981, Predictive Biomarkers and New Therapeutic Strategies in Oncology, Villejuif, F-94805, France.

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http://dx.doi.org/10.1016/j.ejca.2016.05.031DOI Listing
September 2016

Can immunostimulatory agents enhance the abscopal effect of radiotherapy?

Eur J Cancer 2016 07 18;62:36-45. Epub 2016 May 18.

Department of Radiation Oncology, SIRIC SOCRATES Gustave Roussy Cancer Campus, 114 rue E. Vaillant, 94800 Villejuif, France; Université Paris-Saclay, Faculté de Médecine, 94270 Kremlin Bicêtre, France; INSERM U1030, Molecular Radiotherapy, Gustave Roussy Cancer Campus, Villejuif, France; DITEP, Gustave Roussy Cancer Campus, 114 rue E. Vaillant, 94800 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.03.067DOI Listing
July 2016

Holbrook Kohrt: In Memoriam (1977-2016).

Clin Cancer Res 2016 07;22(14):3695-6

Drug Development Department, INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1181DOI Listing
July 2016

Immunophenotyping of Stage III Melanoma Reveals Parameters Associated with Patient Prognosis.

J Invest Dermatol 2016 05 29;136(5):994-1001. Epub 2016 Jan 29.

INSERM U1015, Gustave Roussy Cancer Center, Villejuif, France; University Paris Saclay, Kremlin Bicêtre, France; Gustave Roussy Cancer Center, Villejuif, France; CIC Biothérapie IGR Curie CIC1428, Gustave Roussy Cancer Center, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2015.12.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156792PMC
May 2016

Stability of ipilimumab in its original vial after opening allows its use for at least 4 weeks and facilitates pooling of residues.

Eur J Cancer 2016 May 23;58:8-16. Epub 2016 Feb 23.

Department of Pharmacy, Henri Mondor University Hospitals, AP-HP, 51 Avenue du Maréchal de Lattre de Tassigny, 94010 Créteil, France.

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http://dx.doi.org/10.1016/j.ejca.2016.01.008DOI Listing
May 2016

[What's next in glioblastoma treatment: Tumor-targeted or immune-targeted therapies?].

Bull Cancer 2016 May 28;103(5):484-98. Epub 2016 Mar 28.

Institut Gustave-Roussy, département de radiothérapie, 114, rue Édouard-Vaillant, 94805 Villejuif, France.

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http://dx.doi.org/10.1016/j.bulcan.2016.02.014DOI Listing
May 2016

Tetraspanin CD81, a modulator of immune suppression in cancer and metastasis.

Oncoimmunology 2016 May 18;5(5):e1120399. Epub 2015 Dec 18.

Department of Medicine, Division of Oncology, Stanford University Medical Center , Stanford, CA, USA.

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http://dx.doi.org/10.1080/2162402X.2015.1120399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910756PMC
May 2016

Prognostic impact of the expression of NCR1 and NCR3 NK cell receptors and PD-L1 on advanced non-small cell lung cancer.

Oncoimmunology 2017 13;6(1):e1163456. Epub 2016 May 13.

Gustave Roussy Cancer Campus (GRCC), Villejuif, France; INSERM, GRCC, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT), GRCC, Villejuif, France; University of Paris Sud XI, Kremlin Bicêtre, France; Department of Immuno-Oncology, GRCC, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2016.1163456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283624PMC
May 2016

Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?

Oncoimmunology 2016 Apr 18;5(4):e1112942. Epub 2015 Dec 18.

INSERM, U1015, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 507, Villejuif, France; Drug Development Department, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1112942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839322PMC
April 2016

Prime time for immune-checkpoint targeted therapy at ASCO 2015.

Oncoimmunology 2016 Mar 12;5(3):e1068494. Epub 2015 Aug 12.

Gustave Roussy Cancer Campus, Villejuif, France; INSERM, U1015, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1068494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839368PMC
March 2016

Two cases of immune thrombocytopenia associated with pembrolizumab.

Eur J Cancer 2016 Feb 10;54:172-174. Epub 2015 Dec 10.

APHP, service de médecine interne et immunologie, Hôpital Bicêtre, F-94270 Le Kremlin Bicêtre, France; University of Paris-Sud, F-94043 Kremlin-Bicêtre, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2015.10.073DOI Listing
February 2016

Rationale for anti-OX40 cancer immunotherapy.

Eur J Cancer 2016 Jan 30;52:50-66. Epub 2015 Nov 30.

DITEP, Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, 94805 Villejuif, France; INSERM U1015, Gustave Roussy Cancer Institute, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2015.08.021DOI Listing
January 2016

[PD-L1 expression: An emerging biomarker in non-small cell lung cancer].

Ann Pathol 2016 Jan 14;36(1):94-102. Epub 2016 Jan 14.

Département de biopathologie, MESOPATH, centre Léon-Bérard, 28, rue Laënnec, 69008 Lyon, France; Université Joseph-Fourier, Inserm U823, institut Albert-Bonniot, Grenoble, France.

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http://dx.doi.org/10.1016/j.annpat.2015.11.004DOI Listing
January 2016

Foxp3+ cells are running the show in patients with surgically resected nonsmall cell lung cancer.

Eur Respir J 2015 Dec;46(6):1541-3

Gustave Roussy Cancer Campus, Villejuif, France Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France Drug Development Department, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1183/13993003.01595-2015DOI Listing
December 2015

Upcoming innovations in lung cancer immunotherapy: focus on immune checkpoint inhibitors.

Chin Clin Oncol 2015 Dec;4(4):48

IGustave Roussy, Université Paris-Saclay, F-94805 Villejuif, France.

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http://dx.doi.org/10.3978/j.issn.2304-3865.2015.12.06DOI Listing
December 2015

Tetraspanin CD81 promotes tumor growth and metastasis by modulating the functions of T regulatory and myeloid-derived suppressor cells.

Cancer Res 2015 Nov 1;75(21):4517-26. Epub 2015 Sep 1.

Department of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1021DOI Listing
November 2015

How should we use anti-CTLA-4 antibodies?

Eur J Cancer 2015 Nov;51(17):2686-8

Gustave Roussy Cancer Campus Grand Paris, 114 rue Edouard Vaillant, 94805 Villejuif, France.

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http://dx.doi.org/10.1016/j.ejca.2015.09.002DOI Listing
November 2015

T-cell-based Immunotherapy: Adoptive Cell Transfer and Checkpoint Inhibition.

Cancer Immunol Res 2015 Oct;3(10):1115-22

Department of Medicine, Division of Oncology, Stanford University, Stanford, California.

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http://cancerimmunolres.aacrjournals.org/cgi/doi/10.1158/232
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http://dx.doi.org/10.1158/2326-6066.CIR-15-0190DOI Listing
October 2015

Tumor-targeted and immune-targeted monoclonal antibodies: Going from passive to active immunotherapy.

Pediatr Blood Cancer 2015 Aug 21;62(8):1317-25. Epub 2015 Mar 21.

Antibody and Vaccine Group, Cancer Research UK Experimental Cancer Medicine Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1002/pbc.25508DOI Listing
August 2015

Immune checkpoint modulation for non-small cell lung cancer.

Clin Cancer Res 2015 May;21(10):2256-62

Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2959DOI Listing
May 2015

Dual antibody therapy to harness the innate anti-tumor immune response to enhance antibody targeting of tumors.

Curr Opin Immunol 2015 Apr 7;33:1-8. Epub 2015 Jan 7.

Department of Medicine, Division of Oncology, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2014.12.010DOI Listing
April 2015

Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients.

Sci Transl Med 2015 Apr;7(283):283ra55

Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, 94805 Villejuif, France. INSERM U1015, GRCC, 94805 Villejuif, France. University of Paris Sud XI, 94805 Villejuif, France. Center of Clinical Investigations in Biotherapies of Cancer, CICBT507, GRCC, 94805 Villejuif, France.

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http://dx.doi.org/10.1126/scitranslmed.aaa2327DOI Listing
April 2015

Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications.

Oncoimmunology 2015 Apr 2;4(4):e1008814. Epub 2015 Mar 2.

Gustave Roussy Cancer Campus ; Villejuif, France ; INSERM , U1138; Paris, France ; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Center de Recherche des Cordeliers ; Paris, France ; Université Paris Descartes/Paris V; Sorbonne Paris Cité ; Paris, France.

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http://www.tandfonline.com/doi/full/10.1080/2162402X.2015.10
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http://dx.doi.org/10.1080/2162402X.2015.1008814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485728PMC
April 2015

Paradigm shift in oncology: targeting the immune system rather than cancer cells.

Mutagenesis 2015 Mar;30(2):205-11

Centre de Recherche en Cancérologie de Lyon, 28 Promenade Léa et Napoléon Bullukian, 69008 Lyon, France and Léon Bérard Comprehensive Cancer Center, 28 rue Laennec, 69008 Lyon, France

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http://dx.doi.org/10.1093/mutage/geu073DOI Listing
March 2015

TWIST1 is a direct transcriptional target of MYCN and MYC in neuroblastoma.

Cancer Lett 2015 Feb 1;357(1):412-418. Epub 2014 Dec 1.

Université Lyon 1, F-69000 Lyon, France; Centre Léon Bérard, F-69008 Lyon, France; Pôle des Sciences Cliniques, Lyon, F-69008, France. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.11.056DOI Listing
February 2015

Radiotherapy and toll-like receptor agonists.

Semin Radiat Oncol 2015 Jan;25(1):34-9

Department of Medicine, Stanford University, Stanford, California. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10534296140008
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http://dx.doi.org/10.1016/j.semradonc.2014.07.006DOI Listing
January 2015

Trial watch: Tumor-targeting monoclonal antibodies for oncological indications.

Oncoimmunology 2015 Jan 3;4(1):e985940. Epub 2015 Feb 3.

Gustave Roussy Cancer Campus ; Villejuif, France ; INSERM; U1138 ; Paris, France ; Equipe 11 labellisée par la Ligue Nationale contre le Cancer; Centre de Recherche des Cordeliers ; Paris, France ; Université Paris Descartes/Paris V; Sorbonne Paris Cité ; Paris, France.

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http://dx.doi.org/10.4161/2162402X.2014.985940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368132PMC
January 2015

New insights into the mechanism of action of immune checkpoint antibodies.

Oncoimmunology 2014;3(8):e954869. Epub 2014 Aug 3.

Division of Oncology; Stanford University; Department of Medicine ; Stanford, CA USA.

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http://dx.doi.org/10.4161/21624011.2014.954869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292403PMC
August 2014

Intratumoral immunization: a new paradigm for cancer therapy.

Clin Cancer Res 2014 Apr;20(7):1747-56

Authors' Affiliations: Centre de Recherche en Cancérologie de Lyon, UMR INSERM U1052 CNRS 5286, Centre Léon Bérard, Université de Lyon, Lyon, France; and Division of Oncology, Stanford University, Department of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979477PMC
April 2014

Intratumoral anti-CTLA-4 therapy: enhancing efficacy while avoiding toxicity.

Clin Cancer Res 2013 Oct 21;19(19):5261-3. Epub 2013 Aug 21.

Authors' Affiliations: Department of Medicine, Division of Oncology, Stanford University, Stanford, California; and Centre de Recherche en Cancérologie de Lyon (CRCL), UMR INSERM U1052 CNRS 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817012PMC
October 2013