Aung Ko Win

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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Genet Med 2019 Jul 24. Epub 2019 Jul 24.

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41436-019-0596-9DOI Listing
July 2019

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Nat Commun 2019 05 14;10(1):2154. Epub 2019 May 14.

Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://www.nature.com/articles/s41467-019-09775-w
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http://dx.doi.org/10.1038/s41467-019-09775-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517433PMC
May 2019

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

Authors:
Stephanie L Schmit Christopher K Edlund Fredrick R Schumacher Jian Gong Tabitha A Harrison Jeroen R Huyghe Chenxu Qu Marilena Melas David J Van Den Berg Hansong Wang Stephanie Tring Sarah J Plummer Demetrius Albanes M Henar Alonso Christopher I Amos Kristen Anton Aaron K Aragaki Volker Arndt Elizabeth L Barry Sonja I Berndt Stéphane Bezieau Stephanie Bien Amanda Bloomer Juergen Boehm Marie-Christine Boutron-Ruault Hermann Brenner Stefanie Brezina Daniel D Buchanan Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Jose E Castelao Andrew T Chan Jenny Chang-Claude Stephen J Chanock Iona Cheng Ya-Wen Cheng Lee Soo Chin James M Church Timothy Church Gerhard A Coetzee Michelle Cotterchio Marcia Cruz Correa Keith R Curtis David Duggan Douglas F Easton Dallas English Edith J M Feskens Rocky Fischer Liesel M FitzGerald Barbara K Fortini Lars G Fritsche Charles S Fuchs Manuela Gago-Dominguez Manish Gala Steven J Gallinger W James Gauderman Graham G Giles Edward L Giovannucci Stephanie M Gogarten Clicerio Gonzalez-Villalpando Elena M Gonzalez-Villalpando William M Grady Joel K Greenson Andrea Gsur Marc Gunter Christopher A Haiman Jochen Hampe Sophia Harlid John F Harju Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Shu-Chen Huang Jose Maria Huerta Thomas J Hudson David J Hunter Gregory E Idos Motoki Iwasaki Rebecca D Jackson Eric J Jacobs Sun Ha Jee Mark A Jenkins Wei-Hua Jia Shuo Jiao Amit D Joshi Laurence N Kolonel Suminori Kono Charles Kooperberg Vittorio Krogh Tilman Kuehn Sébastien Küry Andrea LaCroix Cecelia A Laurie Flavio Lejbkowicz Mathieu Lemire Heinz-Josef Lenz David Levine Christopher I Li Li Li Wolfgang Lieb Yi Lin Noralane M Lindor Yun-Ru Liu Fotios Loupakis Yingchang Lu Frank Luh Jing Ma Christoph Mancao Frank J Manion Sanford D Markowitz Vicente Martin Koichi Matsuda Keitaro Matsuo Kevin J McDonnell Caroline E McNeil Roger Milne Antonio J Molina Bhramar Mukherjee Neil Murphy Polly A Newcomb Kenneth Offit Hanane Omichessan Domenico Palli Jesus P Paredes Cotoré Julyann Pérez-Mayoral Paul D Pharoah John D Potter Conghui Qu Leon Raskin Gad Rennert Hedy S Rennert Bridget M Riggs Clemens Schafmayer Robert E Schoen Thomas A Sellers Daniela Seminara Gianluca Severi Wei Shi David Shibata Xiao-Ou Shu Erin M Siegel Martha L Slattery Melissa Southey Zsofia K Stadler Mariana C Stern Sebastian Stintzing Darin Taverna Stephen N Thibodeau Duncan C Thomas Antonia Trichopoulou Shoichiro Tsugane Cornelia M Ulrich Franzel J B van Duijnhoven Bethany van Guelpan Joseph Vijai Jarmo Virtamo Stephanie J Weinstein Emily White Aung Ko Win Alicja Wolk Michael Woods Anna H Wu Kana Wu Yong-Bing Xiang Yun Yen Brent W Zanke Yi-Xin Zeng Ben Zhang Niha Zubair Sun-Seog Kweon Jane C Figueiredo Wei Zheng Loic Le Marchand Annika Lindblom Victor Moreno Ulrike Peters Graham Casey Li Hsu David V Conti Stephen B Gruber

J Natl Cancer Inst 2019 Feb;111(2):146-157

Department of Preventive Medicine, USC Norris Comprehensive Cancer Center.

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http://dx.doi.org/10.1093/jnci/djy099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555904PMC
February 2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 01 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Correction: Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1.

Genet Med 2018 10;20(10):1299

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/gim.2017.265DOI Listing
October 2018

Cancer Risks for PMS2-Associated Lynch Syndrome.

J Clin Oncol 2018 Oct 30;36(29):2961-2968. Epub 2018 Aug 30.

Sanne W. ten Broeke, Heleen M. van der Klift, Carli M.J. Tops, Manon Suerink, Frederik J. Hes, Hans F.A. Vasen, Juul T. Wijnen, and Maartje Nielsen, Leiden University Medical Center, Leiden; Encarna Gomez Garcia, Maastricht University Medical Center, Maastricht; Nicoline Hoogerbrugge, Arjen R. Mensenkamp, and Liesbeth Spruijt, Radboud University Medical Center, Nijmegen; Tom G.W. Letteboer, University Medical Center, Utrecht; Theo A.M. van Os and Egbert J.W. Redeker, Academic Medical Center, Amsterdam; Maran J.W. Olderode-Berends and Yvonne J. Vos, University of Groningen; University Medical Center Groningen, Groningen; Anja Wagner, Erasmus Medical Center, Rotterdam, the Netherlands; Stefan Aretz, University of Bonn; University Hospital Bonn, Bonn; Christoph Engel, Leipzig University; Medizinisch Genetisches Zentrum Bayerstr, Leipzig; Magnus von Knebel Doeberitz, University of Heidelberg; German Cancer Research Center, Heidelberg; Pål Møller, University of Witten-Herdecke, Wuppertal; Nils Rahner, Heinrich-Heine-University, Düsseldorf; Hans K. Schackert, Technische Universität Dresden, Dresden; Verena Steinke-Lange, Medizinische Klinik und Poliklinik IV Campus Innenstadt, Klinikum der Universität München, Munich, Germany; Pål Møller, The Norwegian Radium Hospital; Oslo University Hospital, Oslo, Norway; Inge Bernstein, Hvidovre Hospital, Hvidovre, and Aalborg University Hospital, Aalborg, Denmark; Daniel D. Buchanan, Mark Clendenning, John L. Hopper, Mark A. Jenkins, Christophe Rosty, Ingrid Winship, and Aung Ko Win, The University of Melbourne; Daniel D. Buchanan, Ingrid Winship, and Aung Ko Win, Royal Melbourne Hospital, Parkville, Melbourne, Victoria; Rodney Scott, University of Newcastle, Newcastle, New South Wales, Australia; Albert de la Chapelle, Heather L. Hampel, Rachel Pearlman, and Leigha Senter, The Ohio State University Comprehensive Cancer Center, Columbus, OH; Gabriel Capella and Marta Pineda, Institut d'Investigació Biomédica de Bellvitge, Barcelona, Spain; Steven Gallinger, Mount Sinai Hospital, Toronto, Ontario, Canada; Jane C. Figueiredo and Robert Haile, Cedars-Sinai Medical Center, Los Angeles, CA; Loic Le Marchand, University of Hawaii Cancer Center, Honolulu, HI; Annika Lindblom, Karolinska Institutet; Karolinska University Hospital, Stockholm, Sweden; Noralane M. Lindor, Mayo Clinic Arizona, Scottsdale, AZ; Polly A. Newcomb, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA; and Stephen Thibodeau, Mayo Clinic, Rochester, MN.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.4777
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http://dx.doi.org/10.1200/JCO.2018.78.4777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349460PMC
October 2018

Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families.

J Natl Cancer Inst 2018 Oct 30. Epub 2018 Oct 30.

Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/jnci/djy159DOI Listing
October 2018

Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1.

Genet Med 2018 08 9;20(8):890-895. Epub 2017 Nov 9.

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.

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http://www.nature.com/articles/gim2017185
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http://dx.doi.org/10.1038/gim.2017.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943186PMC
August 2018

Reducing the polyp burden in serrated polyposis by serial colonoscopy: the impact of nationally coordinated community surveillance.

N Z Med J 2017 03 3;130(1451):57-67. Epub 2017 Mar 3.

Department of Haematology and Oncology, The Queen Elizabeth Hospital, Australia, School of Medicine, University of Adelaide, Australia, SAHMRI Colorectal Node, Basil Hetzel Institute for Translational Research, Australia.

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March 2017

Risk factors for metachronous colorectal cancer or polyp: A systematic review and meta-analysis.

J Gastroenterol Hepatol 2017 Feb;32(2):301-326

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/jgh.13476DOI Listing
February 2017

Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis.

Aust N Z J Psychiatry 2016 Sep 15;50(9):842-57. Epub 2016 Mar 15.

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia

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http://dx.doi.org/10.1177/0004867416637920DOI Listing
September 2016

Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status.

Int J Colorectal Dis 2016 Aug 10;31(8):1451-7. Epub 2016 Jun 10.

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1007/s00384-016-2615-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949040PMC
August 2016

Determining the familial risk distribution of colorectal cancer: a data mining approach.

Fam Cancer 2016 Apr;15(2):241-51

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 3, 207 Bouverie Street, Parkville, VIC, 3010, Australia.

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http://dx.doi.org/10.1007/s10689-015-9860-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803603PMC
April 2016

Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer.

J Natl Cancer Inst 2016 Feb 18;108(2). Epub 2015 Nov 18.

Herbert Irving C omprehensive Cancer Center and Division of Digestive and Liver Diseases, Columbia University, Medical Center, New York, NY (FK); Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN (RPO); Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, the Netherlands (CL); Statistical and Data Analysis Center, Harvard School Public Health, Boston, MA (CA); Population Sciences Division, Dana-Farber Cancer Institute, Boston, MA (RCM); Department of Oncology (JB) and Genetics Department (IV), University Hospital Vall d'Hebrón, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain (FB); Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St John's, NL, Canada (RG); Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ (NML); Division of Molecular Genetics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (SNT); Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (PN); Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, Victoria, Australia (AKW, MJ, DDB); Unit of Hereditary Digestive Tract Tumors, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (LB, PS); Clinical Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus, OH (HH); Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA (SS); Harvard Medical School, Boston, MA (SS); Department of Public Health, Erasmus Medical Center, Rotterdam, the Netherlands (EWS); Oncogenomics Group, Genetic Epidemiology Laboratory, The University of Melbourne, Parkville, Victoria, Australia (DDB).

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http://dx.doi.org/10.1093/jnci/djv308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862416PMC
February 2016

Response.

J Natl Cancer Inst 2016 Feb 27;108(2). Epub 2015 Dec 27.

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia (DAO, SGD, AKW).

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http://dx.doi.org/10.1093/jnci/djv385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907360PMC
February 2016

Childhood cancers in families with and without Lynch syndrome.

Fam Cancer 2015 Dec;14(4):545-51

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, 3010, Australia.

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http://dx.doi.org/10.1007/s10689-015-9810-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631656PMC
December 2015

Lynch syndrome and cervical cancer.

Int J Cancer 2015 Dec 14;137(11):2757-61. Epub 2015 Jul 14.

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1002/ijc.29641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573262PMC
December 2015

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

Authors:
Timothy H T Cheng Deborah Thompson Jodie Painter Tracy O'Mara Maggie Gorman Lynn Martin Claire Palles Angela Jones Daniel D Buchanan Aung Ko Win John Hopper Mark Jenkins Noralane M Lindor Polly A Newcomb Steve Gallinger David Conti Fred Schumacher Graham Casey Graham G Giles Paul Pharoah Julian Peto Angela Cox Anthony Swerdlow Fergus Couch Julie M Cunningham Ellen L Goode Stacey J Winham Diether Lambrechts Peter Fasching Barbara Burwinkel Hermann Brenner Hiltrud Brauch Jenny Chang-Claude Helga B Salvesen Vessela Kristensen Hatef Darabi Jingmei Li Tao Liu Annika Lindblom Per Hall Magdalena Echeverry de Polanco Monica Sans Angel Carracedo Sergi Castellvi-Bel Augusto Rojas-Martinez Samuel Aguiar Jnr Manuel R Teixeira Alison M Dunning Joe Dennis Geoffrey Otton Tony Proietto Elizabeth Holliday John Attia Katie Ashton Rodney J Scott Mark McEvoy Sean C Dowdy Brooke L Fridley Henrica M J Werner Jone Trovik Tormund S Njolstad Emma Tham Miriam Mints Ingo Runnebaum Peter Hillemanns Thilo Dörk Frederic Amant Stefanie Schrauwen Alexander Hein Matthias W Beckmann Arif Ekici Kamila Czene Alfons Meindl Manjeet K Bolla Kyriaki Michailidou Jonathan P Tyrer Qin Wang Shahana Ahmed Catherine S Healey Mitul Shah Daniela Annibali Jeroen Depreeuw Nada A Al-Tassan Rebecca Harris Brian F Meyer Nicola Whiffin Fay J Hosking Ben Kinnersley Susan M Farrington Maria Timofeeva Albert Tenesa Harry Campbell Robert W Haile Shirley Hodgson Luis Carvajal-Carmona Jeremy P Cheadle Douglas Easton Malcolm Dunlop Richard Houlston Amanda Spurdle Ian Tomlinson

Sci Rep 2015 12 1;5:17369. Epub 2015 Dec 1.

Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/srep17369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664893PMC
December 2015

Incidence and prevalence of non-melanoma skin cancer in Australia: A systematic review.

Australas J Dermatol 2015 Nov 25;56(4):258-67. Epub 2015 Feb 25.

Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/ajd.12282DOI Listing
November 2015

Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.

Genes Cancer 2015 Nov;6(11-12):445-51

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia; Colorectal Oncogenomics Group, Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701223PMC
http://dx.doi.org/10.18632/genesandcancer.85DOI Listing
November 2015

Aspirin, Ibuprofen, and the Risk of Colorectal Cancer in Lynch Syndrome.

J Natl Cancer Inst 2015 Sep 24;107(9). Epub 2015 Jun 24.

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia (DAO, SGD, RC, DDB, GGG, JLH, MAJ, AKW); Oncogenomics Group, Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia (DDB, MC, CR); University of Queensland, School of Medicine, Herston, Queensland, Australia (CR); Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia (IMW, FAM); Genetic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, Australia (IMW, FAM); Departments of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, South Australia, Australia (JPY); SAHMRI Colorectal Node, Basil Hetzel Institute for Translational Research, Woodville, South Australia, Australia (JPY); School of Medicine, University of Adelaide, South Australia, Australia (JPY); Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia (GGG); QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Herston, Queensland, Australia (BL); Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Parkville, Victoria, Australia (FAM); Department of Medicine, University of Colorado School of Medicine, Denver, CO (DJA); Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA (GC); Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada (SG); Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University, CA (RWH); University of Hawaii Cancer Center, Honolulu, HI (LLM); Molecular Genetics Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (SNT); Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, AZ (NML); Public Health Science

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http://dx.doi.org/10.1093/jnci/djv170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651105PMC
September 2015

Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics.

Cancer Epidemiol Biomarkers Prev 2015 Jul 14;24(7):1130-7. Epub 2015 May 14.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Epidemiology, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491038PMC
July 2015

PIK3CA Somatic Mutation Status in Relation to Patient and Tumor Factors in Racial/Ethnic Minorities with Colorectal Cancer.

Cancer Epidemiol Biomarkers Prev 2015 Jul 20;24(7):1046-51. Epub 2015 May 20.

Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490937PMC
July 2015

Mendelian randomization study of height and risk of colorectal cancer.

Int J Epidemiol 2015 Apr 20;44(2):662-72. Epub 2015 May 20.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA, Department of Medicine and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA, Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA, Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Estonian Genome Center, University of Tartu, Tartu, Estonia, Divisions of Endocrinology and Genetics and Center for Basic Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA, Department of Genetics, Harvard Medical School, Boston, MA, USA, Broad Institute, Cambridge, MA, USA, Genetics of Complex Traits, University of Exeter Medical School, Exeter, UK, Queensland Brain Institute, University of Queensland, Brisbane, QLD, Australia, University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, QLD, Australia, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark, Department of Medical Sciences, Uppsala University, Uppsala, Sweden, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA, CHU Nantes, Service de Génétique Médicale, Nantes, France, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, USC Norris

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http://dx.doi.org/10.1093/ije/dyv082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481609PMC
April 2015

Short-term risk of colorectal cancer in individuals with lynch syndrome: a meta-analysis.

J Clin Oncol 2015 Feb 22;33(4):326-31. Epub 2014 Dec 22.

Mark A. Jenkins, James G. Dowty, Driss Ait Ouakrim, John D. Mathews, John L. Hopper, and Aung Ko Win, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia; John L. Hopper, Institute of Health and Environment, School of Public Health, Seoul National University, Seoul, Korea; Youenn Drouet, Christine Lasset, and Valérie Bonadona, Université Lyon 1, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5558 Laboratoire de Biométrie et Biologie Évolutive, Villeurbanne; and Youenn Drouet, Christine Lasset, and Valérie Bonadona, Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1200/JCO.2014.55.8536DOI Listing
February 2015

Rising incidence of early-onset colorectal cancer in Australia over two decades: report and review.

J Gastroenterol Hepatol 2015 Jan;30(1):6-13

Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, South Australia, Australia; South Australian Health and Medical Research Institute (SAHMRI) Colorectal Node, Basil Hetzel Institute for Translational Research, Woodville, South Australia, Australia; School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1111/jgh.12792DOI Listing
January 2015

Family history and risk of endometrial cancer: a systematic review and meta-analysis.

Obstet Gynecol 2015 Jan;125(1):89-98

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1097/AOG.0000000000000563DOI Listing
January 2015

Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome).

Appl Clin Genet 2014 6;7:183-93. Epub 2014 Oct 6.

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.2147/TACG.S48625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199650PMC
October 2014

Fertility and apparent genetic anticipation in Lynch syndrome.

Fam Cancer 2014 Sep;13(3):369-74

Deakin University Department of Surgery, Geelong Hospital, Ryrie Street, Geelong, VIC, 3227, Australia,

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http://dx.doi.org/10.1007/s10689-014-9714-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357528PMC
September 2014

Family history of colorectal cancer is not associated with colorectal cancer survival regardless of microsatellite instability status.

Cancer Epidemiol Biomarkers Prev 2014 Aug 2;23(8):1700-4. Epub 2014 Jun 2.

Epidemiology Department, University of Washington; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington;

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119483PMC
August 2014

Risk of prostate cancer in Lynch syndrome: a systematic review and meta-analysis.

Cancer Epidemiol Biomarkers Prev 2014 Mar 14;23(3):437-49. Epub 2014 Jan 14.

Authors' Affiliation: Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-1165DOI Listing
March 2014

Colorectal cancer and self-reported tooth agenesis.

Hered Cancer Clin Pract 2014 Mar 10;12(1). Epub 2014 Mar 10.

Department of Health Sciences Research, Mayo Clinic, 13400 East Shea Blvd,, Scottsdale, AZ 85259, USA.

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http://hccpjournal.biomedcentral.com/articles/10.1186/1897-4
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http://dx.doi.org/10.1186/1897-4287-12-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975307PMC
March 2014

Criteria and prediction models for mismatch repair gene mutations: a review.

J Med Genet 2013 Dec 16;50(12):785-93. Epub 2013 Aug 16.

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1136/jmedgenet-2013-101803DOI Listing
December 2013

Response.

J Natl Cancer Inst 2013 Dec 29;105(23):1837-8. Epub 2013 Oct 29.

Affiliations of authors: Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1093/jnci/djt308DOI Listing
December 2013

Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid?

Int J Cancer 2013 Oct 18;133(7):1762-3. Epub 2013 Apr 18.

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http://dx.doi.org/10.1002/ijc.28179DOI Listing
October 2013

BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome.

Am J Surg Pathol 2013 Oct;37(10):1592-602

*Department of Anatomical Pathology †Northern Cancer Translational Research Unit ††Familial Cancer Clinic, Royal North Shore Hospital ∥Department of Pathology, SYDPATH, St Vincents Hospital, Darlinghurst ¶Faculty of Medicine, University of NSW ¶¶Sydney Medical School, University of Sydney, Sydney, NSW §§Department of Molecular and Cellular Pathology ‡Department of Pathology, School of Medicine, University of Queensland ‡‡Envoi Specialist Pathologists, Herston §Cancer and Population Studies Group, Queensland Institute of Medical Research, Brisbane, QLD ∥∥Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Carlton, Vic., Australia #Department of Neuropathology, Institute of Pathology, Ruprecht-Karls University **Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1097/PAS.0b013e31828f233dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773060PMC
October 2013

Is prostate cancer a Lynch syndrome cancer?

Authors:
Aung Ko Win

Asian J Androl 2013 Sep 1;15(5):588-9. Epub 2013 Jul 1.

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http://dx.doi.org/10.1038/aja.2013.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881640PMC
September 2013

Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer.

Cancer Epidemiol 2013 Aug 26;37(4):424-7. Epub 2013 Mar 26.

Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.canep.2013.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684005PMC
August 2013

Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome.

J Natl Cancer Inst 2013 Feb 5;105(4):274-9. Epub 2013 Feb 5.

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Melbourne School of Population Health, Level 3, 207 Bouverie St, University of Melbourne, VIC 3010 Australia.

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http://dx.doi.org/10.1093/jnci/djs525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576323PMC
February 2013

The Australasian Colorectal Cancer Family Registry.

Med J Aust 2012 Nov;197(9):480-1

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November 2012

Risk prediction models for colorectal cancer: a review.

Cancer Epidemiol Biomarkers Prev 2012 Mar 14;21(3):398-410. Epub 2011 Dec 14.

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0771DOI Listing
March 2012

Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.

Cancer Prev Res (Phila) 2012 Feb 5;5(2):328-35. Epub 2011 Dec 5.

Department of Preventive Medicine, Genetic Epidemiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273599PMC
February 2012

Increased cancer risks in myotonic dystrophy.

Mayo Clin Proc 2012 Feb 10;87(2):130-5. Epub 2012 Jan 10.

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.mayocp.2011.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498332PMC
February 2012

Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis.

Fam Cancer 2011 Mar;10(1):1-9

Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Melbourne School of Population Health, The University of Melbourne, Melbourne, VIC 3010, Australia.

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http://dx.doi.org/10.1007/s10689-010-9399-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228836PMC
March 2011