Augustine M Choi

Augustine M Choi

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Augustine M Choi

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Heteroplasmy concordance between mitochondrial DNA and RNA.

Sci Rep 2019 Sep 10;9(1):12942. Epub 2019 Sep 10.

Division of Nutritional Sciences, Cornell University, Ithaca, New York, 14853, USA.

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http://dx.doi.org/10.1038/s41598-019-49279-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737107PMC
September 2019

Circulating Mitochondrial DNA as Predictor of Mortality in Critically Ill Patients: A Systematic Review of Clinical Studies.

Chest 2019 Aug 2. Epub 2019 Aug 2.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2019.07.014DOI Listing
August 2019

Necroptosis: a crucial pathogenic mediator of human disease.

JCI Insight 2019 Aug 8;4(15). Epub 2019 Aug 8.

NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1172/jci.insight.128834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693822PMC
August 2019

DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis.

Cells 2019 Aug 20;8(8). Epub 2019 Aug 20.

Department of Integrated Biomedical Science, Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si 31151, Korea.

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http://dx.doi.org/10.3390/cells8080938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721825PMC
August 2019

Shaping the Path for a Global Oncology Academic Career.

JAMA Oncol 2019 Jul;5(7):931-932

Department of Radiation Oncology, Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2019.0555DOI Listing
July 2019

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.

Nat Commun 2019 Jul 29;10(1):3390. Epub 2019 Jul 29.

Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, 10021, USA.

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http://dx.doi.org/10.1038/s41467-019-11327-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662701PMC
July 2019

Apolipoprotein E and periostin are potential biomarkers of nasal mucosal inflammation: a parallel approach of and secretomes.

Am J Respir Cell Mol Biol 2019 Jun 13. Epub 2019 Jun 13.

Yonsei University College of Medicine, Department of Otorhinolaryngology, Seoul, Korea, Republic of ;

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http://dx.doi.org/10.1165/rcmb.2018-0248OCDOI Listing
June 2019

Developing a Culture of Mentorship to Strengthen Academic Medical Centers.

Acad Med 2019 May;94(5):630-633

A.M.K. Choi is Stephen and Suzanne Weiss Dean, Weill Cornell Medicine, and provost for medical affairs, Cornell University, New York, New York. J.E. Moon is director, Dean's Office Initiatives, Weill Cornell Medicine, New York, New York. A. Steinecke is senior director, Academic Affairs Programs and Engagement, Association of American Medical Colleges, Washington, DC. J.E. Prescott is chief academic officer, Association of American Medical Colleges, Washington, DC.

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http://dx.doi.org/10.1097/ACM.0000000000002498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493700PMC
May 2019

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Science 2019 04;364(6436)

Northwestern University, Evanston, IL, USA.

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http://dx.doi.org/10.1126/science.aau8650DOI Listing
April 2019

Rapidly Improving ARDS in Therapeutic Randomized Controlled Trials.

Chest 2019 Mar 22;155(3):474-482. Epub 2018 Oct 22.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY; First Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, University of Athens Medical School, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414787PMC
March 2019

Autophagy and inflammation in chronic respiratory disease.

Autophagy 2018 8;14(2):221-232. Epub 2018 Feb 8.

a Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine , Weill Cornell Medical College , New York , NY , USA.

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http://dx.doi.org/10.1080/15548627.2017.1389823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902194PMC
February 2019

Diurnal Rhythms Spatially and Temporally Organize Autophagy.

Cell Rep 2019 Feb;26(7):1880-1892.e6

Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, Campus Box 8052, 660 South Euclid Avenue, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442472PMC
February 2019

Plasma mitochondrial DNA and metabolomic alterations in severe critical illness.

Crit Care 2018 12 29;22(1):360. Epub 2018 Dec 29.

Renal Division, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, MRB 418, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s13054-018-2275-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310975PMC
December 2018

Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials.

J Crit Care 2018 10 2;47:49-54. Epub 2018 Jun 2.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, United States; First Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, University of Athens Medical School, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2018.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143398PMC
October 2018

Laminin α1 is a genetic modifier of TGF-β1-stimulated pulmonary fibrosis.

JCI Insight 2018 09 20;3(18). Epub 2018 Sep 20.

Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1172/jci.insight.99574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237225PMC
September 2018

Determination of Early Immune Function in Sepsis and Its Influence on Organ Dysfunction. Is a More Pragmatic Outcome on the Horizon?

Am J Respir Crit Care Med 2018 08;198(3):298-300

1 Joan and Sanford I. Weill Department of Medicine and.

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http://dx.doi.org/10.1164/rccm.201803-0470EDDOI Listing
August 2018

Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort.

Radiology 2018 08 5;288(2):600-609. Epub 2018 Jun 5.

From the Division of Pulmonary and Critical Care Medicine, Department of Medicine (S.Y.A., A.A.D., F.N.R., R.K.P., G.M.H., I.O.R., G.R.W.), Laboratory of Mathematics in Imaging, Department of Radiology (R.H., J.C.R., G.V.S., J.O.O., R.S.J.E.), and Department of Radiology (H.H.), Brigham and Women's Hospital, 75 Francis St, PBB CA-3, Boston, MA 02115; Department of Medicine, Weil Cornell Medical College, New York, NY (F.J.M., A.M.C.); Departments of Medicine (R.P.B.) and Radiology (D.A.L.), National Jewish Health, Denver, Colo; and Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Ala (S.P.B., M.T.D., J.M.W.).

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http://dx.doi.org/10.1148/radiol.2018172688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069608PMC
August 2018

RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction.

JCI Insight 2018 06 7;3(11). Epub 2018 Jun 7.

Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA.

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http://dx.doi.org/10.1172/jci.insight.98411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124406PMC
June 2018

Danger Signals in the ICU.

Crit Care Med 2018 05;46(5):791-798

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine, New York, NY.

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http://dx.doi.org/10.1097/CCM.0000000000003007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905344PMC
May 2018

NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection.

Am J Physiol Lung Cell Mol Physiol 2018 03 2;314(3):L372-L387. Epub 2017 Nov 2.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine , New York, New York.

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http://www.physiology.org/doi/10.1152/ajplung.00393.2017
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http://dx.doi.org/10.1152/ajplung.00393.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900358PMC
March 2018

The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness.

Am J Respir Crit Care Med 2018 02;197(3):300-309

1 Division of Pulmonary and Critical Care Medicine and.

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http://dx.doi.org/10.1164/rccm.201612-2460PPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811949PMC
February 2018

Carbon monoxide in lung cell physiology and disease.

Am J Physiol Cell Physiol 2018 02 8;314(2):C211-C227. Epub 2017 Nov 8.

Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College , New York, New York.

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http://dx.doi.org/10.1152/ajpcell.00022.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866434PMC
February 2018

Plasma surfactant protein-D as a diagnostic biomarker for acute respiratory distress syndrome: validation in US and Korean cohorts.

BMC Pulm Med 2017 Dec 15;17(1):204. Epub 2017 Dec 15.

Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1186/s12890-017-0532-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731189PMC
December 2017

The "Iron"-y of Iron Overload and Iron Deficiency in Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2017 11;196(9):1103-1112

4 Vascular Biology, National Heart and Lung Institute, Imperial College London, London, United Kingdom; and.

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http://dx.doi.org/10.1164/rccm.201702-0311PPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694836PMC
November 2017

Macrolides protect against infection via inhibition of inflammasomes.

Am J Physiol Lung Cell Mol Physiol 2017 Oct 6;313(4):L677-L686. Epub 2017 Jul 6.

Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China;

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http://dx.doi.org/10.1152/ajplung.00123.2017DOI Listing
October 2017

The Objective Identification and Quantification of Interstitial Lung Abnormalities in Smokers.

Acad Radiol 2017 08 15;24(8):941-946. Epub 2016 Dec 15.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, 75 Francis St., PBB, CA-3, Boston, MA 02115.

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http://dx.doi.org/10.1016/j.acra.2016.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472510PMC
August 2017

Mitochondrial DNA in Sepsis.

Curr Opin Crit Care 2017 Aug;23(4):284-290

aDivision of Pulmonary and Critical Care Medicine, Department of Medicine, New York Presbyterian-Weill Cornell Medical Center bDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.

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http://dx.doi.org/10.1097/MCC.0000000000000427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675027PMC
August 2017

Glucose Transporter 1-Dependent Glycolysis Is Increased during Aging-Related Lung Fibrosis, and Phloretin Inhibits Lung Fibrosis.

Am J Respir Cell Mol Biol 2017 04;56(4):521-531

1 Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, New York.

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http://www.atsjournals.org/doi/10.1165/rcmb.2016-0225OC
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http://dx.doi.org/10.1165/rcmb.2016-0225OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449513PMC
April 2017

Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit.

Crit Care 2017 03 26;21(1):73. Epub 2017 Mar 26.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA.

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http://dx.doi.org/10.1186/s13054-017-1658-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366240PMC
March 2017

Metabolites Associated With Malnutrition in the Intensive Care Unit Are Also Associated With 28-Day Mortality.

JPEN J Parenter Enteral Nutr 2017 02 19;41(2):188-197. Epub 2016 Jul 19.

7 The Nathan E. Hellman Memorial Laboratory, Renal Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1177/0148607116656164DOI Listing
February 2017

Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes.

Crit Care Med 2017 Jan;45(1):58-68

1Center for Experimental Therapeutics and Reperfusion Injury, Harvard Institutes of Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. 3Center for Clinical Investigation, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/CCM.0000000000002014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549882PMC
January 2017

Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators.

Crit Care Med 2016 Dec;44(12):e1236-e1245

1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.2Department of Anesthesiology, Perioperative and Pain Medicine, Center for Experimental Therapeutics and Reperfusion Injury, Harvard Institutes of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.3Department of Pediatric Newborn Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.4Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY.

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http://dx.doi.org/10.1097/CCM.0000000000001999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113254PMC
December 2016

Autophagy in Pulmonary Diseases.

Am J Respir Crit Care Med 2016 11;194(10):1196-1207

Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1164/rccm.201512-2468SODOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114440PMC
November 2016

Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma.

Sci Rep 2016 11 4;6:36097. Epub 2016 Nov 4.

Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1038/srep36097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095883PMC
November 2016

The role of necroptosis in pulmonary diseases.

Respir Investig 2016 Nov 7;54(6):407-412. Epub 2016 Jun 7.

Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resinv.2016.03.008DOI Listing
November 2016

NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages.

Nat Med 2016 09 25;22(9):1002-12. Epub 2016 Jul 25.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.4153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204248PMC
September 2016

Autophagy in lung disease pathogenesis and therapeutics.

Redox Biol 2015 2;4:215-25. Epub 2015 Jan 2.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY, USA.

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http://dx.doi.org/10.1016/j.redox.2014.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803789PMC
June 2016

Autophagy and Obesity-Related Lung Disease.

Am J Respir Cell Mol Biol 2016 05;54(5):636-46

Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1165/rcmb.2016-0045PSDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455357PMC
May 2016

Mitochondria in lung disease.

J Clin Invest 2016 Mar 1;126(3):809-20. Epub 2016 Mar 1.

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http://dx.doi.org/10.1172/JCI81113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767339PMC
March 2016

Autophagy: Friend or Foe in Lung Disease?

Ann Am Thorac Soc 2016 Mar;13 Suppl 1:S40-7

2 Joan and Sanford I. Weill Department of Medicine, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1513/AnnalsATS.201507-450MGDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466160PMC
March 2016

Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis.

PLoS One 2015 18;10(3):e0121246. Epub 2015 Mar 18.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121246PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364993PMC
February 2016

Short-term Exposure to Ambient Fine Particulate Matter Increases Hospitalizations and Mortality in COPD: A Systematic Review and Meta-analysis.

Chest 2016 Feb 12;149(2):447-458. Epub 2016 Jan 12.

Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China; Soochow University, Suzhou, China. Electronic address:

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http://dx.doi.org/10.1378/chest.15-0513DOI Listing
February 2016

Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease.

Am J Respir Cell Mol Biol 2016 Feb;54(2):151-60

2 Joan and Sanford I. Weill Department of Medicine, New York-Presbyterian Hospital, New York, New York; and.

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http://dx.doi.org/10.1165/rcmb.2015-0231TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821045PMC
February 2016

Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation.

Transl Res 2016 Jan 23;167(1):7-34. Epub 2015 Jun 23.

Joan and Sanford I. Weill Department of Medicine, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, NY.

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http://dx.doi.org/10.1016/j.trsl.2015.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857893PMC
January 2016

The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases.

Antioxid Redox Signal 2015 Dec 17;23(17):1329-50. Epub 2015 Aug 17.

1 Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital , New York, New York.

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http://dx.doi.org/10.1089/ars.2015.6407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685486PMC
December 2015

Carbon monoxide in the treatment of sepsis.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 23;309(12):L1387-93. Epub 2015 Oct 23.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, New York; and Division of Pulmonary and Crit Care Medicine, Weill Cornell Medical College, New York, New York

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http://dx.doi.org/10.1152/ajplung.00311.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683310PMC
December 2015

Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia.

Am J Physiol Lung Cell Mol Physiol 2015 Oct 28;309(8):L834-46. Epub 2015 Aug 28.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina; Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina; Department of Pathology, Duke University Medical Center, Durham, North Carolina;

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http://dx.doi.org/10.1152/ajplung.00240.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609940PMC
October 2015

Fatty acid synthesis and NLRP3-inflammasome.

Oncotarget 2015 Sep;6(26):21765-6

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical Center, New York, NY, USA.

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http://www.oncotarget.com/fulltext/4781
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http://dx.doi.org/10.18632/oncotarget.4781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673109PMC
September 2015

Impaired oxidative phosphorylation regulates necroptosis in human lung epithelial cells.

Biochem Biophys Res Commun 2015 Aug 14;464(3):875-80. Epub 2015 Jul 14.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.07.054DOI Listing
August 2015

Midkine: In the Middle of the Pathogenesis of Acute Respiratory Distress Syndrome-associated Lung Fibrosis?

Am J Respir Crit Care Med 2015 Aug;192(3):271-2

1 New York-Presbyterian Hospital-Weill Cornell Medical Center Weill Cornell Medical College New York, New York and.

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http://www.atsjournals.org/doi/10.1164/rccm.201506-1084ED
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http://dx.doi.org/10.1164/rccm.201506-1084EDDOI Listing
August 2015

The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells.

Biochem Biophys Res Commun 2015 Jul 30;463(3):440-6. Epub 2015 May 30.

Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.05.103DOI Listing
July 2015

mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation.

Cell Rep 2015 Jul 25;12(1):102-115. Epub 2015 Jun 25.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858438PMC
July 2015

Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages.

Am J Physiol Lung Cell Mol Physiol 2015 May 13;308(10):L1058-67. Epub 2015 Mar 13.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, New York; and Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, New York

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http://dx.doi.org/10.1152/ajplung.00400.2014DOI Listing
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May 2015

Effect of early versus late or no tracheostomy on mortality and pneumonia of critically ill patients receiving mechanical ventilation: a systematic review and meta-analysis.

Lancet Respir Med 2015 Feb;3(2):150-158

Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medical College, New York, NY, USA.

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February 2015

Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.

Am J Physiol Lung Cell Mol Physiol 2014 Nov 12;307(10):L746-57. Epub 2014 Sep 12.

Center for Experimental Therapeutics and Reperfusion Injury, Harvard Institutes of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233292PMC
November 2014

Emerging role of selective autophagy in human diseases.

Front Pharmacol 2014 5;5:244. Epub 2014 Nov 5.

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical Center, New York-Presbyterian Hospital - Weill Cornell Medical College New York, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220655PMC
November 2014

Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins.

Biochem Cell Biol 2014 Oct 6;92(5):370-8. Epub 2014 Aug 6.

a Division of Pulmonary and Critical Care Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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October 2014

Metabolomic derangements are associated with mortality in critically ill adult patients.

PLoS One 2014 30;9(1):e87538. Epub 2014 Jan 30.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America ; Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America.

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September 2014

Molecular regulation of autophagy and its implications for metabolic diseases.

Curr Opin Clin Nutr Metab Care 2014 Jul;17(4):329-37

Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medical College, New York, New York, USA.

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July 2014

The impact of autophagy on cell death modalities.

Int J Cell Biol 2014 4;2014:502676. Epub 2014 Feb 4.

Weil Cornell Medical College, 525 East 68th Street, Room M-522, Box 130, New York, NY 10065, USA.

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June 2014

Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2014 Jun 11;306(11):L1016-25. Epub 2014 Apr 11.

Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China; State Key Laboratory of Respiratory Diseases, Guangzhou, China

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http://dx.doi.org/10.1152/ajplung.00268.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747911PMC
June 2014

Mitochondria in lung biology and pathology: more than just a powerhouse.

Am J Physiol Lung Cell Mol Physiol 2014 Jun 18;306(11):L962-74. Epub 2014 Apr 18.

Columbia University Medical Center, Department of Physiology and Cellular Biophysics, New York, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042189PMC
June 2014

RETRACTED: Effect of early versus late or no tracheostomy on mortality of critically ill patients receiving mechanical ventilation: a systematic review and meta-analysis.

Lancet Respir Med 2014 06 26. Epub 2014 Jun 26.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medical College, New York, NY, USA.

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June 2014

"Ciliophagy": The consumption of cilia components by autophagy.

Autophagy 2014 Mar 7;10(3):532-4. Epub 2014 Jan 7.

Division of Pulmonary and Critical Care Medicine; Brigham and Women's Hospital and Harvard Medical School; Boston, MA USA; Pulmonary and Critical Care Medicine; Weill Cornell Medical College; New York, NY USA.

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http://dx.doi.org/10.4161/auto.27641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077895PMC
March 2014

Epigenetics and the unfolded protein response in the lung: emerging role for microRNAs.

Am J Respir Crit Care Med 2014 Feb;189(3):239-40

1 Division of Pulmonary, Allergy, Critical Care and Sleep Medicine The Ohio State University Columbus, Ohio and James Comprehensive Cancer Center The Ohio State University Columbus, Ohio.

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February 2014

Cecal ligation and puncture-induced sepsis as a model to study autophagy in mice.

J Vis Exp 2014 Feb 9(84):e51066. Epub 2014 Feb 9.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122027PMC
February 2014

Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation.

PLoS Med 2013 Dec 31;10(12):e1001577; discussion e1001577. Epub 2013 Dec 31.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America ; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876981PMC
December 2013

Autophagy: An Integral Component of the Mammalian Stress Response.

J Biochem Pharmacol Res 2013 Sep;1(3):176-188

Weill Cornell Medical College, New York, NY 10065, USA.

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September 2013