August B Smit

August B Smit

UNVERIFIED PROFILE

Are you August B Smit?   Register this Author

Register author
August B Smit

August B Smit

Publications by authors named "August B Smit"

Are you August B Smit?   Register this Author

100Publications

1926Reads

10Profile Views

Proteomics of neurodegenerative diseases: analysis of human post-mortem brain.

J Neurochem 2019 Nov 22;151(4):435-445. Epub 2018 Nov 22.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.14603DOI Listing
November 2019

Deficiency Impacts Hippocampal CA1 Neuronal Excitability, Dendritic Architecture, and Affects Spatial Learning.

Front Cell Neurosci 2019 25;13:465. Epub 2019 Oct 25.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncel.2019.00465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843000PMC
October 2019

SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering.

EMBO J 2019 Sep 1;38(17):e101289. Epub 2019 Aug 1.

Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam and VU Medical Center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.2018101289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717895PMC
September 2019

Early restoration of parvalbumin interneuron activity prevents memory loss and network hyperexcitability in a mouse model of Alzheimer's disease.

Mol Psychiatry 2019 Aug 20. Epub 2019 Aug 20.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-019-0483-4DOI Listing
August 2019

The Effects of Sindbis Viral Vectors on Neuronal Function.

Front Cell Neurosci 2019 8;13:362. Epub 2019 Aug 8.

Laboratory for Neuroregeneration, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncel.2019.00362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694438PMC
August 2019

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.

Neuron 2019 07 3;103(2):217-234.e4. Epub 2019 Jun 3.

Department of Functional Genomics, CNCR, VU University and UMC Amsterdam, 1081 HV Amsterdam, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764089PMC
July 2019

Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson's disease.

Acta Neuropathol Commun 2019 06 3;7(1):84. Epub 2019 Jun 3.

Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-019-0736-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545684PMC
June 2019

A Fast and Economical Sample Preparation Protocol for Interaction Proteomics Analysis.

Proteomics 2019 05 18;19(9):e1900027. Epub 2019 Apr 18.

Department of Molecular and Cellular Neurobiology, Faculty of Science, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201900027DOI Listing
May 2019

Memory strength gates the involvement of a CREB-dependent cortical fear engram in remote memory.

Nat Commun 2019 05 24;10(1):2315. Epub 2019 May 24.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, 1081 HV, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41467-019-10266-1
Publisher Site
http://dx.doi.org/10.1038/s41467-019-10266-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534583PMC
May 2019

Combined cellomics and proteomics analysis reveals shared neuronal morphology and molecular pathway phenotypes for multiple schizophrenia risk genes.

Mol Psychiatry 2019 May 29. Epub 2019 May 29.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-019-0436-yDOI Listing
May 2019

Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays.

SLAS Discov 2019 03 25;24(3):362-385. Epub 2019 Jan 25.

1 The Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of BioAnalytical Chemistry, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/2472555218822098
Publisher Site
http://dx.doi.org/10.1177/2472555218822098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484542PMC
March 2019

A Laser Microdissection-Liquid Chromatography-Tandem Mass Spectrometry Workflow for Post-mortem Analysis of Brain Tissue.

Methods Mol Biol 2018 ;1723:371-383

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-7558-7_21DOI Listing
January 2019

Stress vulnerability promotes an alcohol-prone phenotype in a preclinical model of sustained depression.

Addict Biol 2018 Dec 18. Epub 2018 Dec 18.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/adb.12701DOI Listing
December 2018

Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells.

Nat Biotechnol 2018 Oct 15. Epub 2018 Oct 15.

Brain and Mind Research Institute and Center for Neurogenetics, Weill Cornell Medicine, New York, New York, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/nbt.4259
Publisher Site
http://dx.doi.org/10.1038/nbt.4259DOI Listing
October 2018

Comparative Hippocampal Synaptic Proteomes of Rodents and Primates: Differences in Neuroplasticity-Related Proteins.

Front Mol Neurosci 2018 2;11:364. Epub 2018 Oct 2.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fnmol.2018.00364
Publisher Site
http://dx.doi.org/10.3389/fnmol.2018.00364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176546PMC
October 2018

Neuropathology and cognitive performance in self-reported cognitively healthy centenarians.

Acta Neuropathol Commun 2018 07 23;6(1):64. Epub 2018 Jul 23.

Alzheimer Centre, Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Postbus 7057, 1007 MB, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-018-0558-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055341PMC
July 2018

Noelin1 Affects Lateral Mobility of Synaptic AMPA Receptors.

Cell Rep 2018 07;24(5):1218-1230

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.06.102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088136PMC
July 2018

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling.

Toxicon 2018 Jun 4;148:213-222. Epub 2018 May 4.

AIMMS Division of BioMolecular Analysis, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxicon.2018.04.022DOI Listing
June 2018

Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease.

Acta Neuropathol Commun 2018 06 4;6(1):46. Epub 2018 Jun 4.

Department of Pathology, Amsterdam Neuroscience, VU University Medical Center, PO Box 7057, 1007, MB, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-018-0540-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985582PMC
June 2018

Complex Genetics of Behavior: BXDs in the Automated Home-Cage.

Methods Mol Biol 2017 ;1488:519-530

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research (CNCR), Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-6427-7_25DOI Listing
January 2018

Comparative Analyses of Data Independent Acquisition Mass Spectrometric Approaches: DIA, WiSIM-DIA, and Untargeted DIA.

Proteomics 2018 01;18(1)

Department of Molecular and Cellular Neurobiology, CNCR, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201700304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817406PMC
January 2018

The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory.

Elife 2017 12 4;6. Epub 2017 Dec 4.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.24192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737659PMC
December 2017

Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains.

PLoS One 2017 26;12(7):e0180912. Epub 2017 Jul 26.

Department of Functional Genomics, Centre for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180912PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529015PMC
October 2017

Individual and Familial Susceptibility to MPTP in a Common Marmoset Model for Parkinson's Disease.

Neurodegener Dis 2016 22;16(5-6):293-303. Epub 2016 Mar 22.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000442574DOI Listing
September 2017

Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease.

J Neurosci 2017 09 21;37(39):9361-9379. Epub 2017 Aug 21.

Department of Regeneration of Sensorimotor Systems, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, 1105 BA, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.0084-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596765PMC
September 2017

Correlation profiling of brain sub-cellular proteomes reveals co-assembly of synaptic proteins and subcellular distribution.

Sci Rep 2017 09 21;7(1):12107. Epub 2017 Sep 21.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-11690-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608747PMC
September 2017

High Content Analysis of Hippocampal Neuron-Astrocyte Co-cultures Shows a Positive Effect of Fortasyn Connect on Neuronal Survival and Postsynaptic Maturation.

Front Neurosci 2017 4;11:440. Epub 2017 Aug 4.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University AmsterdamAmsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnins.2017.00440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543085PMC
August 2017

Gene-set analysis shows association between FMRP targets and autism spectrum disorder.

Eur J Hum Genet 2017 06 19;25(7):863-868. Epub 2017 Apr 19.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2017.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520067PMC
June 2017

Oligodendroglial myelination requires astrocyte-derived lipids.

PLoS Biol 2017 05 26;15(5):e1002605. Epub 2017 May 26.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pbio.1002605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446120PMC
May 2017

Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation.

Front Aging Neurosci 2017 17;9:138. Epub 2017 May 17.

Protein Aggregation and Aging, German Center for Neurodegenerative DiseasesTübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnagi.2017.00138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434662PMC
May 2017

Astrocyte lipid metabolism is critical for synapse development and function in vivo.

Glia 2017 04 7;65(4):670-682. Epub 2017 Feb 7.

Department of Molecular & Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, De Boelelaan 1085, Amsterdam, 1081 HV, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/glia.23120DOI Listing
April 2017

A one-week 5-choice serial reaction time task to measure impulsivity and attention in adult and adolescent mice.

Sci Rep 2017 02 15;7:42519. Epub 2017 Feb 15.

Sylics (Synaptologics B.V.), 1008 BA Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep42519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309744PMC
February 2017

Measuring discrimination- and reversal learning in mouse models within 4 days and without prior food deprivation.

Learn Mem 2016 11 17;23(11):660-667. Epub 2016 Oct 17.

Sylics (Synaptologics B.V.), 1008 BA Amsterdam, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/lm.042085.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066605PMC
November 2016

Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex.

Proteomics 2016 10 12;16(20):2698-2705. Epub 2016 Sep 12.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201500400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129514PMC
October 2016

Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development.

Sci Rep 2016 10 17;6:35456. Epub 2016 Oct 17.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics &Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep35456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066275PMC
October 2016

Involvement of astrocyte and oligodendrocyte gene sets in migraine.

Cephalalgia 2016 Jun 7;36(7):640-7. Epub 2015 Dec 7.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, The Netherlands Department of Clinical Genetics, VU University Medical Centre, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0333102415618614DOI Listing
June 2016

The Extracellular Matrix Protein Brevican Limits Time-Dependent Enhancement of Cocaine Conditioned Place Preference.

Neuropsychopharmacology 2016 06 29;41(7):1907-16. Epub 2015 Dec 29.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npp.2015.361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869060PMC
June 2016

At-Line Cellular Screening Methodology for Bioactives in Mixtures Targeting the α7-Nicotinic Acetylcholine Receptor.

J Biomol Screen 2016 Jun 6;21(5):459-67. Epub 2016 Jan 6.

AIMMS Division of BioAnalytical Chemistry, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1087057115625307DOI Listing
June 2016

Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease.

Alzheimers Dement 2016 06 6;12(6):654-68. Epub 2016 Jan 6.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2015.11.002DOI Listing
June 2016

Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1.

EMBO J 2016 06 7;35(11):1236-50. Epub 2016 Apr 7.

Department of Functional Genomics and Clinical Genetics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit (VU) and VU Medical Center, Amsterdam, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.201592244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888233PMC
June 2016

Development of an Online Cell-Based Bioactivity Screening Method by Coupling Liquid Chromatography to Flow Cytometry with Parallel Mass Spectrometry.

Anal Chem 2016 05 20;88(9):4825-32. Epub 2016 Apr 20.

Division of BioAnalytical Chemistry, Vrije Universiteit Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.6b00455DOI Listing
May 2016

Functional characterisation of human synaptic genes expressed in the Drosophila brain.

Biol Open 2016 May 15;5(5):662-7. Epub 2016 May 15.

Brainwave-Discovery Ltd., Hugh Robson Building, 15 George Square, Edinburgh EH8 9XD, UK Institute of Adaptive and Neural Computation, School of Informatics, University of Edinburgh, Edinburgh EH8 9AB, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/bio.016261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874349PMC
May 2016

Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo.

PLoS One 2015 20;10(5):e0127163. Epub 2015 May 20.

Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127163PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438979PMC
April 2016

Impact of genetic variation on synaptic protein levels in genetically diverse mice.

Proteomics 2016 Apr 10;16(7):1123-30. Epub 2016 Mar 10.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201500154DOI Listing
April 2016

Catalytically active tissue transglutaminase colocalises with Aβ pathology in Alzheimer's disease mouse models.

Sci Rep 2016 Feb 3;6:20569. Epub 2016 Feb 3.

Department of Anatomy and Neurosciences, Neuroscience Campus Amsterdam, VU medical center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep20569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738336PMC
February 2016

Sheltering behavior and locomotor activity in 11 genetically diverse common inbred mouse strains using home-cage monitoring.

PLoS One 2014 29;9(9):e108563. Epub 2014 Sep 29.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research (CNCR), Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108563PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180925PMC
November 2015

Time-dependent changes in the mouse hippocampal synaptic membrane proteome after contextual fear conditioning.

Hippocampus 2015 Nov 30;25(11):1250-61. Epub 2015 Mar 30.

Department of Molecular & Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hipo.22432DOI Listing
November 2015

The light spot test: Measuring anxiety in mice in an automated home-cage environment.

Behav Brain Res 2015 Nov 10;294:123-30. Epub 2015 Jun 10.

Section Complex Trait Genetics, Department of Clinical Genetics, VU Medical Center, de Boelelaan 1085, 1081HV, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2015.06.011DOI Listing
November 2015

Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels.

J Cell Biol 2015 Nov 2;211(3):569-86. Epub 2015 Nov 2.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, 1081 HV Amsterdam, Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.201506048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639863PMC
November 2015

Neural ECM in addiction, schizophrenia, and mood disorder.

Prog Brain Res 2014 ;214:263-84

Department of Molecular & Cellular Neurobiology, Center for Neurogenomics & Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, HV Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-444-63486-3.00012-8DOI Listing
August 2015

Within-strain variation in behavior differs consistently between common inbred strains of mice.

Mamm Genome 2015 Aug 28;26(7-8):348-54. Epub 2015 Jun 28.

Sylics (Synaptologics BV), PO box 71033, 1008 BA, Amsterdam, The Netherlands,

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00335-015-9578-7
Publisher Site
http://dx.doi.org/10.1007/s00335-015-9578-7DOI Listing
August 2015

Social defeat-induced anhedonia: effects on operant sucrose-seeking behavior.

Front Behav Neurosci 2015 7;9:195. Epub 2015 Aug 7.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnbeh.2015.00195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528167PMC
August 2015

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.

Biochim Biophys Acta 2015 Jul 21;1854(7):827-33. Epub 2015 Feb 21.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, De Boelelaan 1085, Amsterdam 1081 HV, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbapap.2015.02.008DOI Listing
July 2015

GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome.

J Neurosci 2015 Jun;35(22):8462-79

Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal, Department of Life Sciences, University of Coimbra, 3004-517 Coimbra, Portugal,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.3567-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605323PMC
June 2015

FXR2P Exerts a Positive Translational Control and Is Required for the Activity-Dependent Increase of PSD95 Expression.

J Neurosci 2015 Jun;35(25):9402-8

KU Leuven, Center for Human Genetics and Leuven Institute for Neuroscience and Disease, Leuven, Belgium, VIB Center for the Biology of Disease, 3000 Leuven, Belgium, University of Rome Tor Vergata, Department of Biomedicine and Prevention, 00133 Rome, Italy

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.4800-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605191PMC
June 2015

Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.

Toxins (Basel) 2015 Jun 24;7(7):2336-53. Epub 2015 Jun 24.

AIMMS Division of BioAnalytical Chemistry, Faculty of Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/toxins7072336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516916PMC
June 2015

A 1-night operant learning task without food-restriction differentiates among mouse strains in an automated home-cage environment.

Behav Brain Res 2015 Apr 17;283:53-60. Epub 2015 Jan 17.

Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01664328150002
Publisher Site
http://dx.doi.org/10.1016/j.bbr.2015.01.020DOI Listing
April 2015

C-terminal interactors of the AMPA receptor auxiliary subunit Shisa9.

PLoS One 2014 3;9(2):e87360. Epub 2014 Feb 3.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087360PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911953PMC
December 2014

Proteomic analysis of gliosomes from mouse brain: identification and investigation of glial membrane proteins.

J Proteome Res 2014 Dec 4;13(12):5918-27. Epub 2014 Nov 4.

Department of Molecular & Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam , 1081 HV Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr500829zDOI Listing
December 2014

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

J Proteome Res 2014 Dec 19;13(12):5695-706. Epub 2014 Nov 19.

Department of Molecular and Cellular Neurobiology, and ‡Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University , De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr500697bDOI Listing
December 2014

Optogenetic dissection of medial prefrontal cortex circuitry.

Front Syst Neurosci 2014 9;8:230. Epub 2014 Dec 9.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije University Amsterdam Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnsys.2014.00230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260491PMC
December 2014

Prefrontal gamma-aminobutyric acid type A receptor insertion controls cue-induced relapse to nicotine seeking.

Biol Psychiatry 2014 Nov 11;76(9):750-8. Epub 2014 Feb 11.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics & Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopsych.2014.02.001DOI Listing
November 2014

Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.

Mol Cell Proteomics 2014 Nov 20;13(11):2975-85. Epub 2014 Jul 20.

From the ‡Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, De Boelelaan 1085, 1081HV Amsterdam, The Netherlands;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M113.032086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223485PMC
November 2014

Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action.

Biol Psychiatry 2014 Oct 24;76(8):648-55. Epub 2014 Feb 24.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopsych.2014.02.011DOI Listing
October 2014

Display of individuality in avoidance behavior and risk assessment of inbred mice.

Front Behav Neurosci 2014 16;8:314. Epub 2014 Sep 16.

Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, VU University Amsterdam Amsterdam, Netherlands ; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, VU University Amsterdam Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnbeh.2014.00314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165351PMC
October 2014

mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells.

Cell Rep 2014 Oct 9;9(2):646-60. Epub 2014 Oct 9.

Institute of Molecular Health Sciences, Department of Biology, Swiss Federal Institute of Technology Zurich, ETH Zürich, CH-8093 Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.09.001DOI Listing
October 2014

Specific glial functions contribute to schizophrenia susceptibility.

Schizophr Bull 2014 Jul 16;40(4):925-35. Epub 2013 Aug 16.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, the Netherlands;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/schbul/sbt109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059439PMC
July 2014

TRIM3 regulates the motility of the kinesin motor protein KIF21B.

PLoS One 2013 24;8(9):e75603. Epub 2013 Sep 24.

Department of Molecular Neurogenetics, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075603PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782429PMC
July 2014

Functional gene-set analysis does not support a major role for synaptic function in attention deficit/hyperactivity disorder (ADHD).

Genes (Basel) 2014 Jul 22;5(3):604-14. Epub 2014 Jul 22.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/genes5030604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198920PMC
July 2014

A sustained depressive state promotes a guanfacine reversible susceptibility to alcohol seeking in rats.

Neuropsychopharmacology 2014 Apr 6;39(5):1115-24. Epub 2013 Nov 6.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npp.2013.311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957105PMC
April 2014

Novel cell separation method for molecular analysis of neuron-astrocyte co-cultures.

Front Cell Neurosci 2014 30;8:12. Epub 2014 Jan 30.

Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam Amsterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncel.2014.00012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906515PMC
February 2014

Miniaturized bioaffinity assessment coupled to mass spectrometry for guided purification of bioactives from toad and cone snail.

Biology (Basel) 2014 Feb 13;3(1):139-56. Epub 2014 Feb 13.

AIMMS Division of BioMolecular Analysis, Faculty of Sciences, VU University Amsterdam, De Boelelaan 1081, 1083 HV Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biology3010139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009767PMC
February 2014

Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling.

PLoS One 2013 28;8(5):e63862. Epub 2013 May 28.

Department of Neuroregeneration, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063862PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665836PMC
January 2014

Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.

Nat Commun 2013 ;4:1875

Division of Biochemistry and Center for Biomedical Genetics, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms2900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674282PMC
December 2013

Analytical workflow for rapid screening and purification of bioactives from venom proteomes.

Toxicon 2013 Dec 16;76:270-81. Epub 2013 Oct 16.

AIMMS Division of BioMolecular Analysis, Faculty of Sciences, De Boelelaan 1081, 1083 HV Amsterdam, Amsterdam VU University, The Netherlands; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, VU University Amsterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxicon.2013.10.013DOI Listing
December 2013

Enhanced alcohol self-administration and reinstatement in a highly impulsive, inattentive recombinant inbred mouse strain.

Front Behav Neurosci 2013 30;7:151. Epub 2013 Oct 30.

1Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnbeh.2013.00151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812782PMC
November 2013

Ventromedial prefrontal cortex pyramidal cells have a temporal dynamic role in recall and extinction of cocaine-associated memory.

J Neurosci 2013 Nov;33(46):18225-33

Departments of Molecular and Cellular Neurobiology and Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, 1081 HV, The Netherlands, Department Bioengineering, Stanford University School of Medicine, Stanford, California 94305, Departments of Psychiatry and Cell Biology and Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.

View Article

Download full-text PDF

Source
http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2412-13.2
Publisher Site
http://dx.doi.org/10.1523/JNEUROSCI.2412-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828471PMC
November 2013

Inferring protein-protein interaction complexes from immunoprecipitation data.

BMC Res Notes 2013 Nov 15;6:468. Epub 2013 Nov 15.

Biosystems Data Analysis, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-0500-6-468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874675PMC
November 2013

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

Authors:
Stephan Ripke Colm O'Dushlaine Kimberly Chambert Jennifer L Moran Anna K Kähler Susanne Akterin Sarah E Bergen Ann L Collins James J Crowley Menachem Fromer Yunjung Kim Sang Hong Lee Patrik K E Magnusson Nick Sanchez Eli A Stahl Stephanie Williams Naomi R Wray Kai Xia Francesco Bettella Anders D Borglum Brendan K Bulik-Sullivan Paul Cormican Nick Craddock Christiaan de Leeuw Naser Durmishi Michael Gill Vera Golimbet Marian L Hamshere Peter Holmans David M Hougaard Kenneth S Kendler Kuang Lin Derek W Morris Ole Mors Preben B Mortensen Benjamin M Neale Francis A O'Neill Michael J Owen Milica Pejovic Milovancevic Danielle Posthuma John Powell Alexander L Richards Brien P Riley Douglas Ruderfer Dan Rujescu Engilbert Sigurdsson Teimuraz Silagadze August B Smit Hreinn Stefansson Stacy Steinberg Jaana Suvisaari Sarah Tosato Matthijs Verhage James T Walters Douglas F Levinson Pablo V Gejman Kenneth S Kendler Claudine Laurent Bryan J Mowry Michael C O'Donovan Michael J Owen Ann E Pulver Brien P Riley Sibylle G Schwab Dieter B Wildenauer Frank Dudbridge Peter Holmans Jianxin Shi Margot Albus Madeline Alexander Dominique Campion David Cohen Dimitris Dikeos Jubao Duan Peter Eichhammer Stephanie Godard Mark Hansen F Bernard Lerer Kung-Yee Liang Wolfgang Maier Jacques Mallet Deborah A Nertney Gerald Nestadt Nadine Norton Francis A O'Neill George N Papadimitriou Robert Ribble Alan R Sanders Jeremy M Silverman Dermot Walsh Nigel M Williams Brandon Wormley Maria J Arranz Steven Bakker Stephan Bender Elvira Bramon David Collier Benedicto Crespo-Facorro Jeremy Hall Conrad Iyegbe Assen Jablensky Rene S Kahn Luba Kalaydjieva Stephen Lawrie Cathryn M Lewis Kuang Lin Don H Linszen Ignacio Mata Andrew McIntosh Robin M Murray Roel A Ophoff John Powell Dan Rujescu Jim Van Os Muriel Walshe Matthias Weisbrod Durk Wiersma Peter Donnelly Ines Barroso Jenefer M Blackwell Elvira Bramon Matthew A Brown Juan P Casas Aiden P Corvin Panos Deloukas Audrey Duncanson Janusz Jankowski Hugh S Markus Christopher G Mathew Colin N A Palmer Robert Plomin Anna Rautanen Stephen J Sawcer Richard C Trembath Ananth C Viswanathan Nicholas W Wood Chris C A Spencer Gavin Band Céline Bellenguez Colin Freeman Garrett Hellenthal Eleni Giannoulatou Matti Pirinen Richard D Pearson Amy Strange Zhan Su Damjan Vukcevic Peter Donnelly Cordelia Langford Sarah E Hunt Sarah Edkins Rhian Gwilliam Hannah Blackburn Suzannah J Bumpstead Serge Dronov Matthew Gillman Emma Gray Naomi Hammond Alagurevathi Jayakumar Owen T McCann Jennifer Liddle Simon C Potter Radhi Ravindrarajah Michelle Ricketts Avazeh Tashakkori-Ghanbaria Matthew J Waller Paul Weston Sara Widaa Pamela Whittaker Ines Barroso Panos Deloukas Christopher G Mathew Jenefer M Blackwell Matthew A Brown Aiden P Corvin Mark I McCarthy Chris C A Spencer Elvira Bramon Aiden P Corvin Michael C O'Donovan Kari Stefansson Edward Scolnick Shaun Purcell Steven A McCarroll Pamela Sklar Christina M Hultman Patrick F Sullivan

Nat Genet 2013 Oct 25;45(10):1150-9. Epub 2013 Aug 25.

1] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827979PMC
October 2013

Interaction proteomics of the AMPA receptor: towards identification of receptor sub-complexes.

Amino Acids 2013 May 24;44(5):1247-51. Epub 2013 Jan 24.

Department of Molecular and Cellular Neurobiology, Faculty of Earth and Life Sciences, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, De Boelelaan 1085, Amsterdam, 1081 HV, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00726-013-1461-9DOI Listing
May 2013